On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the pleasure of chatting with the globally minded and endlessly curious Alette Ramos Hunt, PhD, Global Director, Digital Innovation & AI for Drug Discovery at Novartis. From being a third culture kid (Danish dad, Filipino mom, born in Japan, raised in Hong Kong) to becoming one of the sharpest voices connecting biotech, digital health, and AI, Alette brings perspective that’s as international as it is insightful. We explored her fascinating path from studying proteins in Glasgow to driving AI innovation in pharma, and how she’s bridging the gap between molecules, humans, and machines. She reminded us that practical AI and game-changing AI both have a place - one makes us efficient, the other makes us dream bigger. It’s an episode filled with humility, humor, and yes.. human intelligence - proving that even in a world of algorithms, empathy still leads the way. Fun mentions as always: Chandana Fitzgerald Jeff Weness Milind Kamkolkar [00:00-02:00] Bloopers, sunshine, and background banter. [00:03-05:00] Alette’s third-culture upbringing — Japan, Hong Kong, Denmark. [00:05-07:00] Boarding school, biochemistry, and falling in love with proteins. [00:10-12:00] From academia to Pfizer — bringing science to life. [00:13-15:00] Leap to HealthXL — discovering digital health beyond the lab. [00:18-21:00] Entering Novartis — pre-ChatGPT AI strategy and innovation cycles. [00:22-25:00] Practical AI vs. game-changing AI — redefining productivity. [00:24-28:00] AI and drug discovery — startups, partnerships, and collaboration. [00:29-34:00] Lessons on open-minded leadership and partnering with purpose. [00:36-39:00] Jim’s classic closing story and Alette’s advice: Value your strengths, cherish your partners.

On episode #178 of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had a blast chatting with Jonathan Pearce, the thoughtful and forward-looking CEO of Masterlete - and previously the co-founder and CEO of Zipnosis, the company that pioneered asynchronous telemedicine long before it was mainstream. From balancing athlete-grade performance with mental resilience to building a company that refuses to compromise between data and empathy, Jon brings his trademark blend of humility and precision. He also opened up about his own mental health journey, reminding us that resilience isn’t just a leadership skill - it’s a human one. It’s an episode that reminds us - even in a world of algorithms and wearables, the human spirit still defines the win. 🔹 Top 5 Key Takeaways 💻 Lessons from Zipnosis: how DTC missteps became powerful playbooks 🤖 AI enables personalization - not replacement 🔥 Burnout prevention is the next performance edge 📊 From wearables to wisdom: data needs translation 🎯 Leadership = clarity, curiosity, and constant iteration Fun mentions as always: Pat Sukhum John Brownlee 00:00–02:30 — Welcome & banter: from sports metaphors to startup scars02:31–07:00 — Jon’s journey: building Masterlete and learning from athlete ecosystems07:01–12:30 — Data + empathy: the dual pillars of sustainable coaching12:31–16:00 — AI’s promise (and limits) in personal performance16:01–20:00 — Burnout and resilience: redefining “peak” for long-term success20:01–25:00 — The role of digital health platforms in preventive care25:01–30:00 — Leadership lessons: clarity, curiosity, and iteration in practice30:01–34:00 — Future of athlete engagement and real-time feedback34:01–38:00 — Building human connection in scalable tech models38:01–End — Lightning round + advice to Jon’s younger self

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the pleasure of catching up with the one and only Mike McSherry, serial entrepreneur and CEO of Xealth, whose journey goes from quitting Microsoft in Australia to co-founding Boost Mobile, to building the infrastructure behind digital health prescriptions - and now joining forces with Samsung. We covered everything from startups, serendipity, and Surescripts, to what it means to be insanely curious (his words!) and to always find your foxhole friends. Oh, and there may have been a few humble-brags about being the guy who helped power billions of Android phones ad their keyboards. 🦾 🔹 Top 5 Key Takeaways 💡 Curiosity drives innovation - be “insanely curious” about everything. 📈 Luck favors persistence - serendipity comes from hard work. 🤝 Build with trust - surround yourself with “foxhole friends.” 🏥 Healthcare is hard - slow, bureaucratic, but worth transforming. 🌍 Samsung + Xealth - connecting home devices to health data. Fun mentions as always: HLTH USA Samsung Electronics UPMC Providence 📋 00:00 – 02:00 | Catching up with Jim & Eugene, Vegas talk, and welcoming Mike. 📋 02:00 – 06:00 | Mike’s journey from Microsoft to Australia’s biggest web dev company. 📋 06:00 – 09:00 | Lessons from being a “Navy brat” and world traveler. 📋 09:00 – 13:00 | Founding Boost Mobile and its wild telecom legacy. 📋 13:00 – 17:00 | From Nuance to Providence: the path into healthcare. 📋 17:00 – 22:00 | Building Xealth as the “Surescripts for digital health.” 📋 22:00 – 27:00 | Selling to providers and the hard reality of healthcare economics. 📋 27:00 – 33:00 | Integrating with Epic & Cerner: the friend-or-foe dance. 📋 33:00 – 41:00 | The Samsung acquisition story and its big vision for connected health. 📋 41:00 – 49:00 | The future of ambient healthcare and consent-driven data. 📋 49:00 – 52:00 | Mike’s advice: be curious, find your foxhole friends, stay humble.

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the pleasure of hosting Jeff Weness, VP of Growth & Strategy at RefinedScience. From small-town Minnesota roots to global ventures in digital health and now tackling cancer with AI, Jeff’s journey is as unexpected as it is inspiring. We joked about handstands, Russian accents, and Netflix DVDs (yes, mailed in red envelopes!), but his career lessons are pure gold: listen deeply, solve real problems, and don’t be afraid to reinvent yourself. 🚀 🔑 Top 5 Key Takeaways 🎓 Career pivots can fuel long-term impact 🧑‍🤝‍🧑 Partnerships drive innovation in healthcare 🖥️ Geek Squad in hospitals = genius move 💊 Molecule + digital = future of pharma 🤖 AI is reshaping oncology discovery Fun mentions as always: Daniel Couchman Kendall Health Podcast Network John Brownlee Click Therapeutics, Inc. David Benshoof Klein Curio Digital Therapeutics Inc. HealthRHYTHMS Optum 📋 00:00–03:00 | Happy Wednesday banter & Jeff joins 📋 03:00–07:00 | Minnesota roots, 4-H, and Russia exchanges 📋 07:00–11:00 | Insurance career and pivot to MBA/venture 📋 11:00–14:00 | Best Buy innovation & Geek Squad in hospitals 📋 14:00–18:00 | Corporate partnerships at Children’s Minnesota 📋 18:00–23:00 | UnitedHealth & Optum Labs: data, R&D, and digital health 📋 23:00–28:00 | Otsuka: digital therapeutics, patience, and cultural insights 📋 28:00–33:00 | The molecule + digital debate in pharma 📋 33:00–38:00 | Refined Science: AI, oncology, and drug rescue 📋 38:00–46:00 | Cancer prevalence, longevity, and Jeff’s advice: listen deeply

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I welcomed Mark S. Gaunya, GBA, LIA - benefits innovator, wrestling fanatic, rugby convert, and author - who’s on a mission to transform healthcare from a cost center into an asset. From cutting weight in high school wrestling to cutting healthcare costs, Mark brings equal parts grit, vision, and humor to the conversation. Some highlights: 🤼 Wrestling built resilience, discipline, and vision. 📊 Finance background fuels entrepreneurial leadership. 🏥 Healthcare system works well but for the system itself.... 📖 Insurance captives and small businesses We also talked about his new book "Captivated Health: Take Control. Gain Transparency. Leverage Confidence " (pre-order on Amazon - https://www.amazon.com/Captivated-Health-Control-Transparency-Confidence-ebook/dp/B0FDLRTN3M/ref=sr_1_1?crid=2K4OHVOK90G8X&dib=eyJ2IjoiMSJ9.Tm_j3D1shFbNcCw4NyAf7g.KQWzsyxI7bcNVqKl8zp1DYjpRcHsutI26QEvGZx-fIw&dib_tag=se&keywords=Captivated+Health%3A+Take+Control.+Gain+Transparency.+Leverage+Confidence&qid=1758741583&sprefix=captivated+health+take+control.+gain+transparency.+leverage+confidence%2Caps%2C168&sr=8-1) Fun mentions as always: Megan Donnell, MBA, PHR, SHRM-CP, Amanda Goltz, Jennifer Borislow CLU [00:00–02:00] Welcome & pronunciation of “Gaunya” [02:00–06:00] Family roots in healthcare & entrepreneurship [06:00–10:00] Wrestling, resilience, and rugby adventures [10:00–15:00] Finance background → entrepreneurial foundation [15:00–20:00] Transition to insurers: Blue Cross, Cigna, Destiny [20:00–26:00] Leadership lessons, early management challenges [26:00–34:00] Captivated Health model & balance sheet strategy [34:00–39:00] Captives, PBMs, and real employer ROI stories [39:00–49:00] NABIP Consumer Bill of Rights & policy vision [49:00–55:00] Advice to younger self: “Pick wisely”

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I welcomed Jason Campana, the freshly minted CEO of LifeSpeak Inc. who once learned business the hard way - running a painting company without knowing how to paint. From questionable brush strokes to scaling global wellness platforms, Jason’s career is proof that grit beats polish. Fun mentions as always: John Brownlee Kyle Rolfing Jason Von Bank Michael Held All Roads Lead to Minneapolis – Serendipitous intro & John Brownlee connection (00:00–02:00) Jason’s Early Hustle – Bootleg CDs & paper routes (02:00–04:00) College Pro Days – Painting houses, cold sales, and leadership lessons (04:00–07:00) From Paint to Fitness – Joining Fitness on Request → Wellbeats (07:00–10:00) Scaling Corporate Wellness – Pivot to digital, COVID growth, LifeSpeak acquisition (10:00–13:00) Going Public (and Back Private) – IPO, acquisitions, lessons learned (13:00–19:00) Holistic Wellbeing at LifeSpeak – Fitness, mental health, caregiving, substance use (16:00–20:00) AI & Integration – Personalization, platform unification, future of prevention (20:00–24:00) M&A Lessons – Integration pains, cultural challenges, COO perspective (25:00–28:00) What’s Next – New go-to-market, partnerships, prevention at scale (40:00–45:00)

After a summer podcasting break, Jim Joyce and I are back and on this episode of #TheShot of #DigitalHealth Therapy, we finally cornered the legendary Erik de Heus, CEO of SkinVision (yes, only 173 episodes in… shame on us). From biking along Amsterdam canals to catching curveballs in Dutch baseball, to scaling energy startups and now leading SkinVision, Erik’s story is a mix of persistence, humility, and “just follow your dream” wisdom. If you’ve ever wondered how a kid bossing his friends on the playground ends up building digital health business that catch melanoma early and save lives at scale - this one’s for you. Fun mentions as always: Steve Seuntjens HLTH Inc. Martin Kelly ⧉ 00:00 – 02:00 | Opening banter – Jim & Eugene finally get Erik on the mic. ⧉ 02:00 – 06:00 | Early career & HP days – Amsterdam to California and back. ⧉ 06:00 – 09:00 | Childhood & sports – Football, baseball, and bossing friends. ⧉ 10:00 – 15:00 | Energy startup journey – From inception to €500M revenue. ⧉ 15:00 – 20:00 | Scaling challenges – Processes, people, and persistence. ⧉ 22:00 – 28:00 | Philips DirectLife – Competing with Fitbit + coaching layer. ⧉ 30:00 – 33:00 | Birth of PHS Capital – Early digital health investing. ⧉ 34:00 – 41:00 | SkinVision origins – Melanoma detection at scale. ⧉ 42:00 – 47:00 | Aligning incentives – Insurance, NHS, and consumer trust. ⧉ 47:00 – 54:00 | Erik’s advice & future vision – Follow your dream, validate the problem.

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I sit down with the Browns-abandoning, innovation-obsessed Peter Antall, MD. From dissecting cadavers to dissecting telehealth workflows, Peter shares his remarkable journey from pediatrician to healthtech pioneer - building national networks, taming 50 state regulations, and now, nudging GLP-1 users into long-term success. We also find out what gross anatomy has to do with true love. 💀❤️ Fun mentions as always: Olia Hibbard Naomi Allen Roy Schoenberg MD MPH Ido Schoenberg Ken Cahill Murray Brozinsky Julia Hu Neko Health 00:00 – Intro, garage jokes, and Peter’s warm welcome 02:30 – Growing up in Cleveland, med school romance 06:30 – Pediatrics, oncology dreams & the innovation gene 09:00 – Writing Pocket Pediatrician & symptom logic 11:00 – First telehealth forays: Specialists on Call 12:30 – Joining Amwell & the shift to consumer-grade video 18:00 – Why video > audio in clinical care 21:00 – Regulatory nightmare: 50 states, 7 were clear 23:30 – Never a malpractice case: 6M+ visits at Amwell 26:00 – AI note-taking & ambient documentation in care 30:00 – Going public with Amwell & moving on 31:30 – Brightline: Kids’ behavioral health & point solution woes 34:30 – Loneliness across all ages—tech as remedy or divider? 38:00 – Why Lark: scalable, daily AI + coach care 44:00 – GLP-1 support model: 80% persistence at 7 months 48:00 – Advice to young Peter: Think big, disrupt wisely

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I freeze time (and nearly our toes) with the extraordinary Dr Jack Kreindler -longevity doctor, tech founder, and Antarctic explorer. This is only our second-ever long-form episode, and we couldn't be more honored to have Jack join us for it. From designing UX with Douglas Adams to running diagnostics in sub-zero temperatures, Jack shares wisdom at the intersection of tech, healthspan, and philosophy. Yes, there's creatine. Yes, there's metaphysics. And yes, you’ll want to rethink your bedtime and your bucket list. It’s a ride through resilient humans, wild biohacks, and the hilarious humility of medicine in the age of AI. Dont miss this episode: Fun mentions as always: Daniel Kraft, MD Jordan Shlain, MD Peter H. Diamandis ☀️Maneesh Juneja Vishal Gulati 00:00:00 - Jack’s origin story: From tech to medicine 00:05:00 - UX with Douglas Adams & first tech ventures 00:12:00 - Founding CHHP & insights into performance science 00:21:00 - Commitment, coaching, and who makes it through 00:30:00 - The biohacking movement: Hope, hype, and hazards 00:41:00 - The pursuit of longevity vs acceptance of death 00:49:00 - Preventive diagnostics & experience design (Neko, Echo) 00:58:00 - AI in medicine: Augmenting empathy & reducing burnout 01:06:00 - WellFounded & experiential medicine adventures 01:18:00 - South Pole expedition & commencement reflections

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I went from cowbells to code to campaign trails with the one and only Owen McCarthy. We covered a LOT: ✅ Bootstrapping MedRhythms from a napkin sketch to FDA approval ✅ Licensing Stevie Wonder’s music to help stroke patients walk again ✅ Why Maine needs robotic homes (and maybe fewer regulations) ✅ How it feels to run for Governor with a quick thought on the Big Beautiful Bill ✅ oh... and even spoke about the very real Uncle Thump (not Trump) Owen’s journey from logging trucks to legislative vision is the very definition of full circle. And spoiler: you don’t want to miss his advice to future founders 👇 Fun Mentions as always: Steve Seuntjens Marco Mohwinckel Roberto Ascione William Stevens Tech Tour Brian Harris Ann Mond Johnson Megan Coder 00:00–02:00 — Opening from Switzerland: Cowbells, Confessions & TechTour Hosts kick off with scenic vibes and introduce Owen from a mountaintop moment. 02:00–04:30 — Roots in Rural Maine: Logging, Cows & College Dreams Owen shares his upbringing in Patten, Maine, with stories of family, hard work, and dad’s unforgettable advice. 04:30–08:30 — From Engineering to Entrepreneurship: How MedRhythms Started From water treatment sales to Harvard to building a healthtech company with heart (and rhythm). 08:30–14:00 — Bootstrapping to Breakthrough: MedRhythms, Brian Harris & Real Outcomes The early days of therapy, scaling manually, and why universal music licensing took 18 months. 14:00–16:30 — Working with Stevie Wonder: Music, IP, and Big Biz Buy-In The surprising (and charming) tale of pitching Universal and name-dropping Stevie mid-deal. 16:30–21:00 — Defining DTx: Alliance Building, Policy Work, and Lessons Learned What it takes to create an industry from scratch, and why “starting with reimbursement” matters. 21:00–24:00 — The Case for Rural Tech: Healthcare Access in Remote Maine Why digital care and EMS are urgent lifelines in the U.S.’s oldest and second-most rural state. 24:00–27:30 — Jumping into Politics: What Drove Owen to Run for Governor Owen reflects on his decision to run, family conversations, and chasing calm in the hurricane. 27:30–37:30 — Platform Breakdown: Housing, Energy, Healthcare & Modular Dreams A detailed look at his policies: robotic homes, energy equity, and cancer care via telehealth. 37:30–43:00 — Legacy, Leadership & Advice to Future Founders From Uncle Thump to reimbursement-first strategy, Owen gets real about impact and longevity.

Who knew that picking up that Yellow pages at age 24 would lead to Big Brothers Big Sisters Twin Cities ? In this episode #169 of #TheShot of #DigitalHealth Therapy, Jim Joyce & I spoke to Pat Sukhum who took us from attic-living startup grit to changing lives at scale - 2200 youths and counting. We talked Definity Health (sold to United), RedBrick Health (sold to Virgin), Thai food, and why the humble leader is the fiercest force for good. There’s wisdom, there’s vulnerability, there’s even an IRS - Harvard study drop. Pat proves you can be both a CEO and a sidekick, and still lead with heart. Just a few highlights: 🧒 Mentorship isn’t charity, it’s shared transformation. 🤝 Relationships power nonprofit scale and social change. 🧭 Belief plus humility = true leadership growth. 💙 Oh - and don’t forget to say hi to your inner shy kid. Fun mentions as always: John Brownlee Kyle Rolfing Dave Dickey Anthony Miller Daniel Couchman Kendall TimestampTopic Summary[00:00:00]–[00:02:00]Show intro and Pat joins the session[00:02:00]–[00:04:00]Pat’s Minnesota roots and Thai-American identity[00:04:00]–[00:07:00]Early assimilation and family background[00:07:00]–[00:10:00]High school, identity crisis, and Carleton College[00:10:00]–[00:13:00]Deloitte days and founding Definity Health[00:13:00]–[00:17:00]The Big Brothers Big Sisters call and early match[00:17:00]–[00:22:00]Consumer-driven care and Definity’s acquisition[00:22:00]–[00:26:00]RedBrick Health and behavior change lessons[00:26:00]–[00:30:00]Consulting, Bind, and learning to sell[00:30:00]–[00:45:00]CEO transition, mission-driven work, and future vision

⚠️ Warning: Listening to this episode may cause spontaneous inspiration, side effects include rethinking innovation, falling in love with Denmark, and Googling “intelligent bricks.” Meet Anne C. Fleischer — engineer, innovator, former LEO Pharma exec, and now leading Consumer Engagement & New Business Models for Obesity at Novo Nordisk. She grew up in a village so small that your soccer team was whoever showed up to class that day. She wanted to be a helicopter pilot or a doctor, but got motion sickness and couldn’t get into med school...... So she built a new path- literally - constructing heart pump mannequins, NFC-enabled pavement tiles, and eventually digital health products that helped millions. 💥 This episode is a masterclass in doing things differently—with a sense of humor, a killer vision, and a very Danish ability to keep it real. PS. See the link below in comments for a new partnerships portal that the team at Novo announced today at HLTH Europe Fun mentions as always: Malin Johansson Anish Shindore Steve Seuntjens Erik de Heus SkinVision Chandana Fitzgerald Jonathan Weiner Rich Scarfo HLTH Inc. Michael Pace Marina Borukhovich Ali Hashemi Tom Hale 00:00 From Danish Countryside to Dreams of Medicine 07:00 Engineering Meets Creativity 11:00 Building Intelligent Bricks & Early Innovations 13:00 From Fuel Cells to Pharma Strategy 15:00 Founding Leo Innovation Lab 19:00 Build vs. Buy: Pharma’s Digital Dilemma 22:00 Creating Leo Ventures 24:00 Novo Nordisk: Tackling Obesity with Empathy 29:00 Feelings That Shape Health Outcomes 44:00 Anne’s Advice: Speak Boldly, Share Your Purpose

Picture this: you’re 7 years old, just got rejected from every game on the block, so you cannonball into the YMCA pool… 15 years later, you’re one of the top U.S. swimmers. Fast forward another few decades, you’re sitting at a desk once occupied by Andy Molnar at Pear, building the digital health reimbursement movement one payer at a time. 🧠💥 This week on #TheShot of #DigitalHealth Therapy Jim Joyce and I dive into OG territory with Michael Pace, the swimming, startup-slaying, palm-loving advisor. 🔍 MAHA Movement 🖥️ Digital Health’s Role in New Administration Policies 💊 DTx and the Reimbursement Policy 🧠 PDURS Software Guidelines: Pharma Meets Digital 🧩 Trump's executive order on pharma pricing... 👇 Hit play.

Ever wonder what happens when a German economics grad skips the surf lessons in Sydney and builds one of Australia’s fastest-scaling startups? Farina Schurzfeld did exactly that — and then turned the same operational firepower toward mental health. In this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I speak with Farina who shares her journey from launching Groupon in Australia to co-founding Selfapy (Germany’s leading digital mental health platform) and taking it through the bureaucratic gauntlet of DiGA approval - before stepping back to build AndRobin, a sidekick-for-hire growth and ops squad. 💻 Fast growth isn't sustainable without long-term thinking and ethical grounding. 🛒 What scales in e-commerce doesn’t always translate to regulated, B2B-driven systems. 🏥 Selfapy didn’t start with DiGA—but became a pioneer anyway. They built for users, then adapted as policy opened the reimbursement door. 🛠️ Startups need senior operators, not just advisors or consultants AndRobin fills the Series A void with hands-on executional leadership. 🚪 Step out when your superpower isn’t needed anymore 👇If you're in digital health, health tech, or just building something that matters - this one’s for you Fun mentions as always: Roberto Ascione Frontiers Health Andrew Mason Bundesinstitut für Arzneimittel und Medizinprodukte hims & hers

What do William Wallace, smart pill bottles, and pharma sales have in common?They all showed up in this week's #TheShot of #DigitalHealth Therapy. Jim Joyce and I had a chat with Innes Meldrum - Scottish-born, New Jersey-rooted CEO of AdhereTech. Innes unpacks his journey from flunking high school to running $Big brands and now cracking one of healthcare’s stickiest problems: medication adherence. We covered: 🤖 Tech vs. human behavior in adherence 🧩 Pharma’s paradox (have to watch to get more) 🧠 Leadership = authenticity + heart 🫥 Tech must be invisible for patients 📈 Adherence is greater than acquisition in long run Big lessons. Big heart. Big impact. 🎧 Listen now and learn why belief might just be your biggest asset. Fun mentions as always: Josh Stein Dave Griffiths 🇮🇪 Kaiser Permanente YourCoach.Health 00:00 – 03:00 — Opening Banter & Setup Eugene, Jim & Innes kick things off across time zones with laughs and backstory. 03:00 – 08:00 — From Scotland to Kentucky Innes shares his multicultural roots, flunking high school, and a summer teaching soccer in the US. 08:00 – 14:00 — Career Leap: Tech to Pharma The unexpected journey from engineering at Nortel to global marketing at Novartis. 14:00 – 18:00 — Mental Health & Authentic Leadership How neuroscience drew Innes in—and why emotional connection is key to commercial success. 18:00 – 22:00 — Joining AdhereTech Why Innes took the CEO seat and what surprised him when he arrived. 22:00 – 27:00 — Solving the Adherence Problem A dive into AdhereTech’s smart pill bottle and how it’s changing patient behavior. 27:00 – 32:00 — Pharma Economics & Ownership Gaps The financial burden of non-adherence—and who really owns the problem in healthcare. 32:00 – 36:00 — Stress, Behavior, and Health Coaching Exploring the real reasons patients don’t take meds—and how health coaching can help. 36:00 – 41:00 — Resilience & System Innovation Innes reflects on leadership growth, system constraints, and building a startup culture. 41:00 – 45:00 — Future Vision & Final Advice A keynote moment: belief, purpose, and what Innes would tell his younger self.

What do angel investing, cosmonaut training, and funding a 10-year health community project have in common? Esther Dyson. Obviously. In our latest episode #164 of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the pleasure to catchup with Esther. We covered: 💸 Why she funded Wellville to rebuild social fabric in underserved communities (and what she really learned) 🧬 What 23andMe got right — and what it didn’t... 📕 Her next chapter: writing "Term Limits", a book about being human in the age of infinite AI 🧠 And why “making new mistakes” is a better life motto than “move fast and break things” Esther’s wisdom is as timeless as her curiosity — and we’re just glad she finally made it on #TheShot. 😅 Fun mentions as always: Matthew Holt Unity Stoakes Marina Borukhovich Rick Brush Peter H. Diamandis Linda Avey Stepan Pachikov Anne Wojcicki 🧭 Section Breakdown (Topics + Timestamps): Intro & Background Setup Esther joins & shares how this podcast started as a pandemic experiment. ⏱️ 00:00 – 04:00 Esther’s Life Journey in 3 Speeds From Oppenheimer roots to Forbes to cosmonaut training. ⏱️ 04:00 – 08:00 Cosmonaut Training & Health Discovery How a space detour saved her life. ⏱️ 08:00 – 12:00 Wellness Habits & Biohacking Wisdom Swimming, eating early, and NOT eating at cocktail parties. ⏱️ 12:00 – 14:00 Becoming an Angel Investor How a million-dollar challenge turned her into an investor. ⏱️ 14:00 – 17:00 Why She Started Wellville From judging the Healthcare XPrize to 10 years of social fabric repair. ⏱️ 18:00 – 25:00 Hard Truths About Systems & Poverty Trust, grants-as-drugs, and funding that's actually fair. ⏱️ 25:00 – 27:00 On Government, Prevention & Food Systems Sugar taxes, vaccines, and the real trends that matter. ⏱️ 27:00 – 29:00 23andMe’s Rise, Fall, and Lessons She got the education, not the return. ⏱️ 29:00 – 33:00 Term Limits & Being Fully Human Why we need constraints, not infinity — and why Pam the hygienist is the real hero. ⏱️ 35:00 – 44:00

Imagine starting life with a speech impediment and ending up as a Broadway's beatboxing, improv master - that’s Anthony Veneziale’s journey! A presentation and storytelling expert, Grammy-nominated star of both Broadway and film, he is the co-creator of the acclaimed Freestyle Love Supreme, an improvised, hip hop, live musical performance with a rolling cast of characters including the likes of Lin-Manuel Miranda, Christopher Jackson and Daveed Diggs. Anthony proves that the best ideas come from embracing yes, and... Jim Joyce and I had a blast on today's episode of #TheShot of #DigitalHealth today as it was packed with epic freestyle moments, brain science, and enough energy to light up all of Las Vegas. 🏆 🔥 Bonus: We even got Anthony to drop a custom freestyle rap about ClearIP! If you want to laugh, learn, and maybe rethink how improv can revolutionize creativity, mental health, and business, this one’s for you. 🎧👇 Top 3 Key Insights 🎭 Improv fuels confidence, creativity & problem-solving 🧠 Brain science proves improv enhances cognition & mental agility 💡 Saying ‘Yes, And’ unlocks innovation & business success Fun mentions as always: Matthew Holt Daniel Couchman Kendall Roberto Ascione Kristin Milburn Frontiers Health Rachel Loui Christie Pitts Matt Loeb #YesAnd #Improvisation #Creativity #Neuroscience #MentalFitness #FreestyleInnovation Podcast Breakdown 1️⃣ Welcome & Icebreaker (00:00 - 03:00) 👉 Hosts discuss podcast rankings, meeting Anthony, and app testing. 2️⃣ Anthony’s Origin Story (03:00 - 07:00) 👉 From speech therapy struggles to founding Freestyle Love Supreme. 3️⃣ The Birth of Freestyle Love Supreme (07:00 - 10:00) 👉 How a college improv troupe shaped his career & led to Broadway. 4️⃣ The Magic of Improv (10:00 - 14:00) 👉 Why improv is a tool for confidence, creativity & problem-solving. 5️⃣ Neuroscience & Improv (14:00 - 19:00) 👉 Brain science behind improv, fMRI studies, and cognitive benefits. 6️⃣ Mindless, Inc. & AI-Powered Games (19:00 - 25:00) 👉 AI-driven mental fitness games & their impact on mental health. 7️⃣ The Art of Freestyle & Startup Pitches (25:00 - 29:00) 👉 Freestyling startup pitches at AARP & turning ideas into rap. 8️⃣ Clear IP Freestyle Moment (29:00 - 33:00) 👉 Anthony creates an impromptu rap about Jim’s startup. 9️⃣ The Power of Yes, And (33:00 - 36:00) 👉 How embracing ‘yes, and’ can transform business & creativity. 🔟 Closing Advice & Big Takeaways (36:00 - End) 👉 Anthony’s wisdom for entrepreneurs & creators.

🎤 Music as medicine? More like a prescription for good vibes! 🎶 In our latest episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I jammed with Rachel Francine, CEO of Musical Health Technologies aka SingFit, the company bringing singing-based therapy to people worldwide. Turns out, belting out tunes can be as powerful as a prescription—especially for dementia care 🤯 Rachel’s journey? From growing up in a beanbag factory (yes, really) with an opera-singing inventor dad, to riding every major tech wave before it was cool. Now, she’s scaling music therapy to change lives at scale—because, let’s be real, we could all use some more dopamine and less stress. What’s next? SingFit is making waves in care homes, hospitals, and even football clubs.. Top 5 Key Takeaways 🎵 Singing is therapy 🧠 Music unlocks memories 💊 Less meds, more music Singing reduces anxiety & agitation 🎤 Singing reduces anxiety & agitation 🌍 Scaling music therapy Fun mentions as always: Andy Tubman Chandana Fitzgerald Francesca Wuttke Ali Parsa Jorge Juan Fernández García ⏱️ [00:00 - 04:00] | Intro & Banter Jim & Eugene joke about podcast delays, St. Patrick’s Day, and Irish gifts to the White House. ⏱️ [04:00 - 10:00] | Meet Rachel Francine: A Life in Tech From VHS vs. Beta to CitySearch, Rachel recounts her wild career journey. ⏱️ [10:00 - 15:00] | Growing Up in a Beanbag Factory with an Opera-Singing Inventor Dad Yes, really. Also, how patents were dinner table conversations. ⏱️ [15:00 - 20:00] | From Nashville to Music Tech: The Road to SingFit Rachel’s experience in the music industry & early digital platforms. ⏱️ [20:00 - 27:00] | What is SingFit? And Why Singing is Medicine Explaining the science of active music therapy and its impact. ⏱️ [27:00 - 33:00] | Case Studies: Dementia, Autism & Mental Health How singing reduces agitation, anxiety, and even hospital visits. ⏱️ [33:00 - 37:00] | Scaling Music Therapy: The Market Challenge Why music therapists are rare & how SingFit is bridging the gap. ⏱️ [37:00 - 40:00] | The Future of SingFit & Big Announcements Coming Expansion to B2C, football clubs, and a mystery mega-partnership. ⏱️ [40:00 - 42:00] | Jim’s “Famous Last Question” Rachel’s advice? Follow the money & understand the music business. ⏱️ [42:00 - End] | Wrap-Up & Subscribe! Final thoughts, audience shout-outs, and the importance of hitting that subscribe button.

#TheShot of #DigitalHealth Therapy took a deep dive with Payal Bhandari M.D. ,and let’s just say... minds were blown, hearts were inspired, and Jim Joyce almost started singing “Country Roads” when he heard Payal was from West Virginia. 🎶 From AI & diagnostics to functional medicine vs. traditional care, Payal didn't hold back. If you think your annual check-up is comprehensive, wait until she tells you how our health system is stuck in the past and why your microbiome is screaming for attention. 🧐 We tackled everything—personalized medicine, integrative care, RFK Jr.'s "Make America Healthy Again" movement, and why your data is so valuable.. If you want science, heart, and a side of humor in your healthcare discussions, this is the episode for you! 🎙️ 🔥 Top 5 Key Takeaways 1️⃣ 🧠 Data knows more than you think about you.. 2️⃣ 💊 Traditional & functional medicine should be friends, not foes. 3️⃣ 📊 AI + biomarkers = precision medicine goldmine. 4️⃣ 💰 U.S. healthcare system = sick care, not healthcare. 5️⃣ 🎵 Music is medicine. Literally. Fun mentions as always: Mark Hyman, MD Sandra Scheinbaum, Ph.D. Larry Shore MD, FAAFP Matthew Holt Lucy Reynales Ritesh Patel ViVE Marina Borukhovich

Ever wonder what happens when you mix a lawyer’s mindset, cold-calling resilience, and a deep love for healthcare investment? You get Richard Lungen, a guy who turned rejection into an art form and convinced 100+ healthcare execs to hand over $$$ for HC9 Ventures. 💰💡 From almost becoming a prosecutor to building provider networks before networks were cool, Richard’s journey is packed with wisdom, war stories, and a deep appreciation for just how hard healthcare really is. We covered everything from sales tactics to the power of listening to quarterly reports like it’s the latest #TheShot of #DigitalHealth Therapy podcast with Jim Joyce. If you're an entrepreneur trying to break into healthcare, here’s your golden ticket to understanding how to navigate this industry—spoiler alert: it’s a LONG game. 🏆 Top 5 Key Takeaways 🚀 📞 Cold calling still works – Just know your target! 📊 Listen to earnings calls – They’re free market intelligence! ⏳ Healthcare sales take years – So start now. 🦾 Know your audience – Investors & buyers don’t want guesses. 💡 .... and great advice from Richard to entrepreneurs.. Fun mentions: Pete Antunes John Wray Tim Wentworth Charlie Falcone #DigitalHealth #HealthcareInvestment #VentureCapital #Entrepreneurship #HC9Ventures #TheShotPodcast