In this podcast, we provide a summary of the scientific consensus on Menopause and highlight resources for women looking to understand how they can address the multifaceted challenges and management strategies associated with the menopausal transition, focusing on both the physical and psychosocial impacts. A significant theme is the importance of lifestyle medicine, advocating for prescriptive resistance exercise to combat bone and muscle loss (osteoporosis and sarcopenia) and targeted nutrition (like the Mediterranean diet and adequate protein/Vitamin D intake) to manage cardiometabolic risks. This may help women alongside evidence-based medical interventions like Menopausal Hormone Therapy (MHT) and Cognitive Behavioral Therapy (CBT) for symptom management.We also created a companion guide for men on our youtube channel
Have more questions on how to handle Menopause and its symptoms? Use our Notebook and ask your own questions.
For more science and technology insight check out our research site Bear Wynd Technology
Vibe coding is a new approach to creating software where you use everyday language to tell an Artificial Intelligence (AI) tool what you want to build, rather than writing lines of computer code yourself.
This development style, coined by AI researcher Andrej Karpathy, shifts the focus from manual coding to guiding AI assistants through a conversational process.
Essentially, you "talk" or "text" to the AI, and it generates the functional code for you.Here's how it generally works:
1. Describe Your Idea: You start by giving the AI a high-level description of what you want your app or software feature to do, using plain English. For example, you might say, "Create a basic HTML landing page with a headline and a button".
2. AI Generates Code: The AI interprets your request and produces the initial code, often along with explanations or comments.
3. Refine and Iterate: You review the AI's output, test it, and provide feedback or new instructions to make changes, add features, or fix issues. This back-and-forth conversation helps you refine the project until it meets your vision.
Learn more about this exciting new area and how to get started.
Pets are cool until their hair is falling out and they won't stop scratching.
When do you go to the Vet? Is it their food?
Answers to these questions and more.
Market Research is a vital skill that Founders and Product developers need to be successful.This podcast summarizes a step by step process for creating a quantative approach to market comparisons.
Learn more at Bear Wynd's research site
The webpage also includes a free web tool to create your first comparison.
This Podcast explores various facets of AI agent and chatbot development and deployment, highlighting both technical solutions and significant industry challenges. Several sources introduce diverse open-source chatbot platforms like Botpress, Microsoft Bot Framework, Rasa, and Tock, detailing their functionalities and target users, from visual builders to code-driven frameworks. Concurrently, other documents address crucial data management and integration issues faced by organizations of all sizes, emphasizing problems with data quality, legacy systems, security, and the need for automation in the age of AI.
Vaccines are incredibly effective- maybe one of the most effective medicines that science has ever created.
Listen to understand what you need to know about how to make the right decisions for you and your family.
Disclosure: This episode was made using AI to generate the podcast hosts. All other steps; gather the information, reviewing information for accuracy, reviewing the script and post-production were performed by a scientist.
Vaccines offer profound health and economic benefits for individuals and communities. Globally, vaccines have saved an estimated 150 million children over the last 50 years, notably reducing infant mortality by 40%. Measles vaccination alone averted over 60 million deaths from 2000-2023.
For young adults, staying current with immunizations is vital for maintaining personal health and independence, preventing dangerous diseases and their severe complications like brain damage or death.
Vaccination also protects vulnerable individuals who cannot be immunized, fostering community immunity.Economically, routine childhood immunizations in the U.S. for those born 1994-2023 are projected to prevent 508 million illnesses and 1.1 million deaths, leading to net societal savings of $2.7 trillion—an estimated $11 saved for every $1 invested. Beyond direct prevention, vaccines contribute to improved cognition and school attainment, enhancing long-term economic productivity. Emerging evidence also suggests certain vaccines, like the shingles vaccine, may reduce dementia risk.
Welcome back to the podcast. Episode 1 of this seasom starts a new educational series "What You Need to Know"
IMPORTANT DISCLOSURE:
This episode has AI generate hosts. We felt that the back and forth was a better way to create a conversations that feel real to listeners.
We want to be very clear that all evidence and information used to curate the script was exclusively from published, peer-reviewed sources. All 12 sources were each reviewed and the podcast itself was then reviewed for accuracy.
More about Medical Marijuana:
We are tackling one of the fastest growing over the counter medicines in North America; Cannabis AKA Weed, Bud- just to name a few names.
The new "TASE" website will be dedicated to educational resources that are based on the medical communities insight to help all of use make good decisions.
Learn more here: Through A Scientist's Eyes- Learn About Science page
For our Youtube page we have a related video that delves into Cannabis from another angle.
What Should You Do Before Using?
If you're thinking about trying cannabis for health reasons, here are some smart steps:
Cannabis and its parts (THC and CBD) might offer some relief for certain conditions, especially pain, MS spasms, and some cancer-related symptoms. However, it's really important to be careful. The effects can vary, there are potential side effects and drug interactions, and the products aren't always regulated.
BOTTOM LINE:
Always talk to a healthcare professional before you start using cannabis for any health reason. They can help you make an informed decision that's best for your health.
How do explore the question of how to make a brain? How did genomic sequencing and genetic manipulation change the nature and speed of the research. This episode goes through my journey as a brain scientist as the human genome project was just in its infancy.
There is an intimate relationship between gene expression, developmental biology and the environment. In this episode we will discuss how this plays out to shape humans using a thought experiment: getting the human species ready to survive on other planets.
It is the science behind an on-going SciFi short story that I have been writing for a few years now: Acchret's Children
How do you translate signals into action? How do you remember your actions?
For the cell, similar to a computer, it is a series of additive changes- in this case to the packaging of DNA that make it either easier or more difficult for the DNA to be accessed by RNA polymerase, the ultimate control of gene expression.
How did normal cell biology let scientists come up with mRNA vaccines "so fast"...about 80 years of research went into these overnight vaccines.
These brand new vaccines are built an enormous amount of data on vaccines here are a few of the ones I read:
https://www.sciencefriday.com/articles/the-origin-of-the-word-vaccine/https://www.immunology.org/celebrate-vaccines/public-engagement/guide-childhood-vaccinations/how-vaccines-work
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253346/
https://vk.ovg.ox.ac.uk/vk/how-do-vaccines-work
Video explanation of immunity and vaccines and More detailed medical term one
NCBI- Pubmed findable science articles on the history of mRNA for vaccinces
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597572/
https://www.frontiersin.org/articles/10.3389/fimmu.2019.00594/full
https://www.nature.com/articles/s41541-020-0159-8
https://www.nejm.org/doi/full/10.1056/NEJMcibr2009737
CDC information on the current mRNA viruses for COVID19
https://www.cdc.gov/vaccines/covid-19/hcp/mrna-vaccine-basics.html
https://www.cdc.gov/vaccines/covid-19/info-by-product/pfizer/index.html
https://www.cdc.gov/vaccines/covid-19/info-by-product/moderna/index.html
How do we regulate a gene? In this episode I'll go through some of the experimental biology that lead us to understand the "Who, What, When and Why" of a gene. This will be a deep dive that takes the basic question of how do DNA, RNA and Protein relate and provide some "meat" on the bones.
Some related videos and sites that visualize some of these concepts:
As we start our journey together, I think it's important to start with something that's topical and as you can imagine the most topical thing for most of us in 2021 is the pandemic. If want to dig deeper here are some resources
"mRNA vaccines — a new era in vaccinology | Nature Reviews Drug Discovery" https://www.nature.com/articles/nrd.2017.243
"Three decades of messenger RNA vaccine development - ScienceDirect" https://www.sciencedirect.com/science/article/abs/pii/S1748013219301483
Katalin Karikó spent the 1990s collecting rejections.
"Essentials of Cell Biology | Learn Science at Scitable" https://www.nature.com/scitable/ebooks/essentials-of-cell-biology-14749010/contents/
Lewis Thomas
Search for more videos on Cell Biology "search for Introduction to Cell Biology"
Specific YouTube channels me or my kids use for science learning:
https://youtube.com/c/inanutshell
Khan academy (website or Youtube channel)
Biology4kids (website or Youtube channel)
This episode is a quick introduction to who I am and what this series is about:
A weekly exploration of the process of science, working back from something that the average person knows and exploring the Iceberg of facts, experiments and failure that went into shaping that Iceberg
