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Solving the Puzzle with Dr. Datis Kharrazian
Datis Kharrazian, PhD, DHSc, DC, MS, MMSc, FACN
57 episodes
1 week ago

Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian's experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has innovated through trial and error in working with complex patient cases.

Dr. Kharrazian discusses evidence-based models incorporating diet, nutrition, and lifestyle — protocols hard won through decades of working with tough, complex patient cases. 


His goal is to help teach you effective models for so-called “mystery” symptoms and conditions so you can regain control of your health and life.


Hashimoto's: Solving the Puzzle, is a new online course from Dr. Kharrazian, who is the originator of evidence-based strategies for managing autoimmune Hashimoto's hypothyroidism. This course has the most complete and current information for managing Hashimoto's available.


You can find more information at drknews.com.

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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Health & Fitness
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All content for Solving the Puzzle with Dr. Datis Kharrazian is the property of Datis Kharrazian, PhD, DHSc, DC, MS, MMSc, FACN and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian's experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has innovated through trial and error in working with complex patient cases.

Dr. Kharrazian discusses evidence-based models incorporating diet, nutrition, and lifestyle — protocols hard won through decades of working with tough, complex patient cases. 


His goal is to help teach you effective models for so-called “mystery” symptoms and conditions so you can regain control of your health and life.


Hashimoto's: Solving the Puzzle, is a new online course from Dr. Kharrazian, who is the originator of evidence-based strategies for managing autoimmune Hashimoto's hypothyroidism. This course has the most complete and current information for managing Hashimoto's available.


You can find more information at drknews.com.

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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Health & Fitness
Episodes (20/57)
Solving the Puzzle with Dr. Datis Kharrazian
Episode 57: Dr. Joseph Pizzorno’s Insights on Functional Medicine and Environmental Health

In this episode, Dr. Kharrazian is joined by renowned physician Dr. Joseph Pizzorno, a pioneering voice in environmental medicine and toxicology. Together, they dive into the hidden world of environmental toxins—discussing the staggering number of chemicals we're exposed to every day, why testing for toxins can be more complex than most realize, and which common exposures may be silently sabotaging our health.


Dr. Pizzorno reveals the challenges in accurately measuring toxic load, the wide differences in our bodies’ abilities to detoxify, and why focusing on exposure and biological damage is often more useful than hunting for specific chemicals in the blood or urine. You'll learn about practical strategies for identifying and reducing toxin exposure, the synergistic effects of multiple chemicals, and simple steps you can take to support your body’s natural defenses.


  • For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
  • For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
  • For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/


00:00 Assessing Exposure and Detox Challenges

03:37 "Assessing Synergistic Environmental Toxins"

07:09 "Toxic Load vs. Disease Correlation"

11:24 Tea Habits and Water Concentration

16:24 Chemical Impact on Neurological Health

17:48 Persistent Human-Made Molecules

23:20 Bisphenols Lowering Children's IQ

26:18 Chemical Food Sources & Glyphosate Exposure

28:26 Cerrillini's Impact on Glyphosate Regulation

32:50 "Assessing Kidney Toxicity via EGFR"

36:44 "Enhancing Body Detoxification"

37:42 "Detox Strategy: Sweat and Monitor"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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1 week ago
39 minutes 57 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 56: Labs To Monitor In Patients With Hemochromatosis

In today’s episode, Dr. Christy Sutton breaks down the crucial markers to monitor for iron overload, from classic liver enzymes and iron panels to the often-overlooked cardiovascular and autoimmune risk factors that can clue you into complications before they become serious. You’ll learn about ancillary labs to watch for side effects in the liver, kidneys, brain, hormones, cardiovascular system, and more. Dr. Sutton unpacks the practical nuances of interpreting test results, why “mildly elevated” liver enzymes should never be dismissed, and how overlapping factors like copper, magnesium, and vitamin deficiencies can shape both diagnosis and management. 


Join Dr. Christy Sutton's 6-hour Kharrazian Institute Master Class on Iron Overload & Undiagnosed Anemias and learn the protocols 90% of practitioners miss.

Enroll: pages.kharrazianinstitute.com/sutton-anemia


  • For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
  • For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
  • For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/


00:00 Hemochromatosis Patient Lab Monitoring

04:45 Glutathione Testing and Liver Health

06:35 Type 1 Diabetes and Celiac Link

12:24 Hemochromatosis and Cardiovascular Risk

16:29 Copper and Ceruloplasmin Testing Insights

19:49 Copper, Iron, Zinc: Balancing Act

24:09 "Solving The Puzzle" Podcast Promo







Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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3 weeks ago
25 minutes 21 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 55: Navigating Anemia

Anemia affects millions but is often misunderstood or oversimplified. Anemia isn’t just about having low iron. It means you don’t have enough healthy red blood cells or hemoglobin to get vital oxygen to your tissues, organs, and brain. 

Host Chrissy Sutton breaks down the many different forms of anemia, from iron-deficiency to anemia of inflammation, and even discusses why you can actually have too much iron and still be anemic.


We’ll explore how to spot anemia not just with lab work, but by recognizing physical signs like paleness, fatigue, brittle nails, and even changes in your tongue and the whites of your eyes. Dr. Sutton highlights why anemia is more than just feeling tired—it’s tied to everything from exercise intolerance and heart palpitations to developmental delays in children and increased risk for disorders like ADHD.


This episode also unpacks the confusing overlap between high ferritin from inflammation versus hemochromatosis, goes in-depth on the impact of pregnancy and menstruation on iron levels, and shares actionable tips for both clinicians and patients. 


To learn more, enroll in the Master Class “Iron Overload and Undiagnosed Anemias” at https://pages.kharrazianinstitute.com/sutton-anemia


  • For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
  • For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
  • For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/


00:00 Anemia and Heart Strain Connection

10:13 Low Iron Risks in Pregnancy

11:40 Early Pregnancy Iron Supplementation

18:14 Acid Reducers Impact Iron Levels

26:50 Pregnancy: Nutrient Absorption Challenges

31:43 "Decoding Iron Deficiency Causes"

34:08 Iron Deficiency Anemia Symptoms

40:51 Vitamin A Deficiency Risk Factors

47:24 "Copper's Role in Iron Regulation"

53:34 Diagnosing Hemolytic Anemia

54:26 Managing Aplastic Anemia Basics

01:01:52 Lead Cabinet Toxicity Solved

01:06:09 Ferritin Management Without Blood Removal

01:11:14 Digestive Challenges of Low Stomach Acid




Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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4 weeks ago
1 hour 11 minutes 54 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 54: Understanding Dyslexia and Childhood Processing Disorders

In this episode, Dr. Kharrazian dives into childhood developmental disorders, with a special focus on dyslexia and processing challenges. Learn why children struggle with reading, writing, or social interaction and how sensory and motor coordination issues are linked to brain development.


The conversation breaks down the different types of developmental disorders, from learning and sensory processing to motor skills, psychological health, and communication abilities. Dr. Kharrazian will clarify what dyslexia really is and explore its genetic roots, signs, symptoms, and why early diagnosis is critical. 


You’ll also hear insights on sensory processing disorders, motor tics, behavioral challenges, and how functional medicine can support children—and adults—facing these challenges by optimizing brain health and development. 


To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.

  • For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
  • For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
  • For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/


00:00 Identifying Learning Disorder Pathways

05:15 Dyslexia Awareness and Diagnosis Progress

15:37 "Dyslexia-Induced Cognitive Fatigue"

19:40 Early Dyslexia Impact on Children

25:35 Dyslexia: Genetics and Coping Strategies

30:01 Dyslexia Screening: Nine Yes Indicators

33:17 Supporting Dyslexia: Diagnosis and Brain Health

37:23 Factors Impacting Brain Development

46:34 Neurorehab: Develop Weak Brain Areas

48:17 Sensory and Motor Disorders in Autism

54:02 Frontostriatal Pathway and Tics

01:00:47 "Understanding PANDAS/PANS in Children"

01:08:19 Comprehensive Child Development Disorder Checklist

01:09:25 "Pediatric Functional Medicine Overview"

01:14:30 Functional Medicine & Nutrition Education




Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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1 month ago
1 hour 15 minutes 41 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 53: Functional Medicine Approaches to Childhood Neurodevelopmental Disorders

In this episode, Dr. Kharrazian dives into the rising rates and complexities of childhood developmental disorders, such as autism, ADHD, dyslexia, and sensory processing issues, and discusses why so many parents and even healthcare professionals feel overwhelmed or unsupported when it comes to helping these children thrive.

Whether you’re a healthcare practitioner, parent, or someone interested in the foundations of healthy brain development, this conversation will give you an understanding of childhood developmental challenges and actionable tools to make a difference. 


To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.

  • For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
  • For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
  • For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/


00:00 "Muscle Mass Essential for Longevity"

03:05 Sarcopenia Significantly Increases Mortality Risk

08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise

10:56 Gut-Muscle Axis: Impact on Fitness

13:09 Gut-Muscle Connection: Sarcopenia Insights

17:33 Muscle Metabolism and Protein Sufficiency

20:02 Protein Intake Crucial for Muscle Maintenance

25:30 Muscle Issues: Causes and Solutions

27:26 Creatine: Muscle Boost and Benefits

32:19 Accelerated Muscle Aging Process

35:52 Improving Muscle Metabolism with Autophagy

38:58 Statins Linked to Muscle Dysfunction

40:00 Statin Impact on Muscle Health

43:08 Trigger Points and Myofascial Pain

48:17 Myofascial Syndromes and Muscle Dysfunction

52:52 Functional Medicine Training and Resources


Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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1 month ago
1 hour 26 minutes 47 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 52: The Impact of Bone and Joint Health on Chronic Illness Recovery

In this episode, Dr. Datis Kharrazian explains what happens to our muscles as we age and why maintaining muscle mass is crucial for mobility, bone density, cognition, metabolic and immune health, and recovery from chronic illness. You’ll hear actionable insights about sarcopenia (age-related muscle loss), the muscle-gut connection, the power of myokines, and how hormones, nutrition, and strategic exercise can make a life-or-death difference.


You’ll hear evidence-based guidance on protein intake, key nutrients, common causes of dysfunctional muscle metabolism, and how to identify and address issues like statin-induced myopathy and abnormal muscle tone.


To dive deeper, enroll in the Kharrazian Institute’s Degenerative Joint, Muscle, and Bone Conditions Course.

Sign up here: https://pages.kharrazianinstitute.com/ki-bone-joint


  • For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
  • For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
  • For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/


00:00 "Muscle Mass Essential for Longevity"

03:05 Sarcopenia Significantly Increases Mortality Risk

08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise

10:56 Gut-Muscle Axis: Impact on Fitness

13:09 Gut-Muscle Connection: Sarcopenia Insights

17:33 Muscle Metabolism and Protein Sufficiency

20:02 Protein Intake Crucial for Muscle Maintenance

25:30 Muscle Issues: Causes and Solutions

27:26 Creatine: Muscle Boost and Benefits

32:19 Accelerated Muscle Aging Process

35:52 Improving Muscle Metabolism with Autophagy

38:58 Statins Linked to Muscle Dysfunction

40:00 Statin Impact on Muscle Health

43:08 Trigger Points and Myofascial Pain

48:17 Myofascial Syndromes and Muscle Dysfunction

52:52 Functional Medicine Training and Resources


Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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1 month ago
54 minutes 3 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 51: How Bone, Joint, and Muscle Health Influences Chronic Disease Recovery

In this episode, you’ll learn how movement directly influences your metabolism, immune system, brain function, and even the diversity of your gut microbiome. Dr. Kharrazian explains the critical role of messenger proteins released during physical activity, why maintaining muscle mass and bone density is key to longevity, and how inflammation can undermine your body’s ability to recover.


  • For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
  • For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
  • For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/


00:00 Introduction to the Podcast

00:30 How Physical Movement Impacts Health

01:54 Bone Volume, Osteopenia, and Health Consequences

02:56 Toxic Chemicals, Bone Loss, and Aging

03:50 Muscle Mass, Sarcopenia, and Mortality

04:38 Movement, Depression, and Brain Chemistry

05:15 Movement, Myokines, and Immune Function

05:59 Microbiome Diversity, Gut Health, and Inactivity

06:32 Overtraining Syndrome and its Red Flags

07:11 Exercise, Mitochondrial Health, and Chronic Disease

07:49 Movement & Brain Health: Repair, Mood, and Cognitive Disorders

08:25 Sedentary Lifestyle in Children & Sarcopenia Risks

09:45 Medical Management of Osteoporosis and Arthritis

10:55 Inflammation, Muscular and Skeletal Degeneration

12:16 Body Fat, Skinny Fat, and Inflammation

12:46 Insulin Surges and Systemic Inflammation

13:31 Microbiome, Leaky Gut, and Chronic Inflammatory Disease

16:04 Food, Environmental Toxins, and Inflammation

18:09 Protein Intake and Recovery from Chronic Disease

19:12 Sleep, Sleep Apnea, and Bone Health

19:57 Regenerative Medicine Therapies

21:34 Conclusion and Podcast Resources



Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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2 months ago
22 minutes 25 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 50: The Role of Relationships and Support in Managing Autoimmunity

Welcome to "Solving the Puzzle with Dr. Datis Kharrazian." In this episode, we dive into the environmental and lifestyle factors that impact autoimmunity. From evaluating case reviews to understanding the significance of relationships, stress, and sleep, we explore how these elements shape autoimmune diseases. Discover how proper lifestyle medicine is crucial, and why it’s more than just about supplements. Learn about sleep disorders, chemical exposures, and the role of circadian rhythms in modulating the immune system. For more details, visit drknews.com.


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Patient Screening and Case Review Process

07:55 Sleep's Impact on Immune Function

11:27 Rheumatoid Arthritis: Sleep's Vital Role

16:15 Stress, Autoimmunity, and IL-17 Dynamics

22:13 Exercise & Autoimmunity: Personalized Approach

26:57 Chemical Bio-Transformation: Can vs. Can't

31:17 Chemical Sensitivity and Immune Response

37:45 BPA Study on Autoimmunity Impact

44:16 "Identifying Active Heavy Metal Exposure"

50:48 Chemical & Immune Tolerance Issues

54:42 Avoiding Challenge Tests: Prioritize Immune Reactivity

01:01:47 Optimizing Liver Detox and Nutrition

01:06:54 Glutathione Protocol for Heavy Metals

01:11:03 Glutathione Inhalation for Lung Health

01:14:38 Dr. Kharrazian Podcast Resources


Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

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6 months ago
1 hour 15 minutes 49 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 49: Navigating Parasitic Infections

In this episode of "Solving the Puzzle with Dr. Datis Kharrazian," we dive into the intricate world of gastrointestinal health, focusing specifically on the common pathogen Helicobacter pylori (H. pylori) and various parasites affecting the human body. Dr. Kharrazian as explores the pathophysiological mechanisms of these infections, their clinical presentations, and the potential systemic health issues they can trigger, including autoimmune diseases, cardiovascular risks, and gastrointestinal disturbances. 


Learn more at drknews.com


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 H. Pylori Pathogenesis Explained

05:45 H. Pylori: Symptoms and Risks

11:58 H. Pylori's Broad Health Impact

19:24 Urea Breath Test for H. Pylori

25:40 Digestive Health Supplement Strategies

32:05 Malaria Symptoms and Transmission Overview

36:49 Dormant Malaria Parasite Reactivation

39:24 Asymptomatic Malaria: Hidden Transmission Risk

46:07 Parasite Transmission Via Poor Hygiene

51:12 Deworming Benefits for HIV Patients

57:24 Mixed Results in Autoimmune Disease Treatment

01:04:05 "Chronic Infections and Immune Function"

01:06:46 Sleep's Role in Immunity

01:14:47 Bile Acids: Key Immune Regulators

01:21:25 Mucosal Immunity and Microbiome Health

01:22:37 Factors Affecting Microbiome Diversity




Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.



Hosted on Acast. See acast.com/privacy for more information.

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8 months ago
1 hour 26 minutes 17 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 48: Neurological Health and Interventions with Randy Vawdry, NP-C

In today's episode, Dr. Kharrazian interviews Randy Vawdry, NP-C, a respected nurse practitioner who has carved a niche in the realm of functional medicine. With a background ranging from nursing home care to urgent care, Randy brings a wealth of practical experience to our discussion about neurological health and treatment. We dive into his innovative approaches to neurological health, exploring how metabolic health, hormone optimization, and understanding traumatic brain injuries can revolutionize patient care. Randy shares invaluable insights from his clinical practice and educational endeavors, shedding light on how practitioners can master the complexities of brain health to improve outcomes for themselves, their patients, and even their loved ones.


SIGN UP HERE: http://pages.kharrazianinstitute.com/vawdrey-neurological-disorders


Learn more at kharrazianinstitute.com

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Master Class with Expert Clinician

04:26 Optimizing Neurological Health Priorities

06:35 Value of Mastering Functional Medicine

10:16 Prioritize Brain Health for Practitioners

13:18 Simplifying Complex Concepts

17:40 Lifestyle Medicine and Hormone Optimization

20:41 Rethinking Functional Medicine Approach

24:35 Functional Medicine's Inexperience Problem

28:33 "Symptoms Are the Disease"

29:17 Lifestyle Choices and Alzheimer's Prevention

33:59 "Promoting Continuous Glucose Monitoring"

37:19 Master Class on Neurological Care

39:27 Podcast Disclaimer and Dr. Kharrazian's Disclosures

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.



Hosted on Acast. See acast.com/privacy for more information.

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9 months ago
40 minutes 5 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 47: Chronic Lyme Disease and Mold Illnesses

This episode dives into the complex world of chronic infections, with a particular focus on the far-reaching impacts of Lyme disease and mold-related illnesses. We explore the debilitating symptoms of chronic Lyme disease, from severe fatigue and chronic joint pain to the potential for neurological damage and heart complications. Our discussion highlights the often-misunderstood overlap between ongoing infections and autoimmune responses, revealing how mismanagement of Lyme can lead to persistent health challenges. Mold illness and mycotoxins are also discussed.


Learn more at drknews.com


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Ticks must be removed quickly to prevent Lyme.

03:13 Bull's-eye rash indicates Lyme disease; treat immediately.

08:29 Chronic Lyme disease severely impacts daily functioning.

10:31 Lyme disease disrupts metabolism, causing persistent symptoms.

16:05 Infection triggers lasting brain inflammation, causing issues.

17:06 Bacteria location influences Lyme disease symptoms severity.

20:19 Post Lyme syndrome involves neurological autoimmune issues.

25:21 Chronic Lyme impacts include autoimmunity, microbiome issues.

29:01 Mold triggers allergies; toxic mold releases mycotoxins.

33:14 Sensitivity to mold varies; immune reactions differ.

33:54 Common cleaning methods can't completely remove mold.

39:37 Mycotoxins influence intestinal permeability and healing.

42:48 Mycotoxins trigger immune reactions, affecting mold-sensitive individuals.

45:11 Gut dysbiosis is influenced by mycotoxins and immunity.

48:42 Mold sensitization can cause lifelong health issues.

52:02 Mold spores cause symptoms; mycotoxins affect everyone.


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10 months ago
55 minutes 11 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 46: Navigating Chronic Infections

In this episode, Dr. Kharrazian discusses chronic infections and antibiotic resistance. Topics include hidden pathogen reservoirs, the role of biofilms in persistent illnesses, and why future generations may struggle with basic bacterial treatment. Hear about innovative strategies like probiotics, fecal transplants, and natural disruptors combating resistant strains. Discover how maintaining immune health is key to battling evolving bacteria and learn practical tips to protect yourself.


Learn more at drknews.com


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Bacteria classified by Gram stain, cause illness.

07:25 Intestinal permeability leads to severe systemic inflammation.

10:58 Systemic inflammation, endotoxemia: barrier breakdown, severe illness.

20:21 Mycobacterium tuberculosis can reactivate when immunocompromised.

26:06 Biofilms cause 80% of chronic bacterial infections.

28:25 Biofilms influence IBS and ulcerative colitis severity.

33:04 Biofilms cause persistent infections and antibiotic resistance.

38:51 Combine medication and natural medicine for bacterial biofilms.

45:30 Genetic predisposition causes recurrent E. coli infections.

50:48 Poor hygiene impacts multiple body systems significantly.

55:28 Bacteria developed resistance, antibiotics became ineffective.

01:05:44 Probiotics with antibiotics reduce post-surgery complications.

01:11:30 Antibiotics disrupt crucial short chain fatty acid levels.

01:13:13 Use antibiotics, probiotics, and short-chain fatty acids.

01:18:06 Candida aids immunity but causes problems if overpopulated.






Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.



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11 months ago
1 hour 20 minutes 31 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 45: Understanding Chronic Viral Infections

In this episode Dr. Kharrazian explores the world of chronic infections, such as Epstein-Barr Virus (EBV), Hepatitis C, Covid, and Human Cytomegalovirus (CMV), and their impact on our immune system. He explores how some pathogens hide within our bodies and reemerge when our immunity is compromised.


He discusses the latest research linking these infections to autoimmune diseases and even cancer, and emphasizes the importance of enhancing our immune defenses rather than just relying on antiviral treatments. He covers a wide range of topics from the basics of virology, the dynamics of long COVID, and the sobering realities of Hepatitis C and Human Papillomavirus (HPV), to the ripple effects of viral infections on our overall health.


Learn more at drknews.com


For patient-oriented courses, visit https://drknews.com/online-courses/


For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 MHC proteins activate cells to fight infection.

06:16 Long COVID factors: comorbidities, age, severity, inflammation, genetics

13:50 Viral infection can trigger chronic inflammatory conditions.

17:27 Long COVID linked to persistent antinuclear antibodies.

22:53 Autoantibodies may form due to SARS-CoV-2 infection.

27:28 Hepatitis B virus vaccine increases MS risk.

33:58 Alphaviruses include herpes, 53% exhibit antibodies.

39:30 Cytomegalovirus linked to autoimmune diseases, immune manipulation.

45:39 Chronic Epstein Barr causes inflammation, cancer risk.

52:02 Hepatitis C symptoms: diverse and system-wide impacts.

57:33 High treatment costs spark global protests, denials.

01:00:33 PCR measures viral load; biomarkers assess liver damage.

01:06:08 Identify underlying health issues causing recurring infections.



Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.



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1 year ago
1 hour 7 minutes 35 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 44: Chronic Infections and the Immune System

This episode explores the world of the immune system's response to pathogens and chronic infections. Dr. Kharrazian discusses the intricate mechanisms pathogens use to evade the immune system, leading to chronic infections and reactivations. He speaks on the impact of immune compromise, genetic factors, and other environmental influences on the severity of infections and autoimmune diseases. He also discusses the pivotal role of protein intake, the formation of antibodies, and the potential link between pathogen-induced inflammation and neurodegenerative diseases.


Learn more at drknews.com


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Different pathogens have unique effects on health.

06:30 Local infection can trigger widespread systemic inflammation.

10:32 Chronic infections can reactivate and cause autoimmunity.

18:51 Pathogens can lead to Alzheimer's disease development.

24:38 Inflam aging causes inflammation and body pain.

27:47 Blood contains complement systems, T and B cells, and innate adaptive immunity. Persistent pathogens hide in tissues, evade immune barriers. Chronic infections indicate immune system issues.

33:02 Complement proteins indicate pathogenic load in blood.

40:40 Importance of proteins in immune system activation.

46:00 Genetics impacts response to viral infections.

49:28 Weakened immunity can cause severe cytokine storms.

55:02 Tick and pathogen invasion into tissues explained.

58:53 Micronutrient deficiencies can impact immune compromise significantly.


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1 year ago
1 hour 2 minutes 50 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 43: Hormonal Imbalance Overview

In this episode, Dr. Datis Kharrazian discusses hormone disorders and their impact on puberty, perimenopause, menopause, and andropause. He discusses the onset of hormone-related issues, such as puberty and perimenopausal transition, and provides evidence-based strategies for addressing menstrual irregularities, hormone imbalances, adrenal function, and more. Dr. Kharrazian also delves into the effects of hormone replacement therapy (HRT), the role of essential fatty acids and seed oils, and the impacts of stress on hormone levels. Additionally, he answers questions on hormone therapy, hormone depletion, and the evaluation of pituitary tumors. Listeners will gain insights into managing hormone-related health conditions and understanding the complexities of the endocrine system.


Learn more at drknews.com


For patient-oriented courses, visit https://drknews.com/online-courses/


For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Addressing imbalances, electrolyte depletion, and functional medicine.

04:42 Underweight PCOS patients need specific health care.

07:17 Chart discussed general symptoms, diagnostic steps, treatment.

10:32 Analyze protein and fat intake for health.

15:30 Weight loss can release stored toxins and hormones.

18:29 Steroids and sleep, light, sound sensitivity strategies.

20:14 Perimenopausal insomnia and low testosterone concerns addressed.

23:31 Podcast content not a substitute for medical advice.


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1 year ago
24 minutes 9 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 42: Hormone Therapy Strategies

In this episode, Dr. Kharrazian provides insights on growth hormone deficiency, testosterone replacement therapy, strategies for PCOS and infertility, and much more. From discussing the use of growth hormone stimulating peptides to addressing heavy menstrual bleeding and gallbladder issues, this episode offers evidence-based approaches to optimizing endocrine function.


Learn more at drknews.com


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Gradual use of HRT therapy based on age.

08:27 Customized hormone therapy starts with low doses.

13:03 Testosterone therapy aids weight loss in men.

20:15 Testosterone replacement therapy may benefit men with diabetes.

23:10 Testosterone replacement therapy in men is safe.

30:20 Men with low testosterone treated with injections.

35:05 Managing testosterone levels in men, potential issues.

38:09 Dietary and lifestyle strategies impact hormones clinically.

48:13 Music therapy, blood sugar, ketogenic diet, sleep issues.

52:33 Nutraceuticals impact insulin resistance; fasting benefits.

56:09 Women in menopause may experience gallbladder issues.

01:03:26 Nutraceutical protocols, insulin signaling, PCOS treatment options.

01:10:20 Evaluate hypoglycemia, insulin resistance, and dietary history.

01:16:18 Decide on hormone therapy based on risks.

01:17:43 Understanding aging and its impact on health.

01:22:32 Podcast content not a substitute for medical advice.



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1 year ago
1 hour 23 minutes 10 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 41: Understanding Hormone Disorders

In this episode we dive into the intricate web of hormone imbalances, menstrual disorders, and andropause. We explore the impact of estrogen and progesterone imbalances on the menstrual cycle, as well as the role of prostaglandin imbalances in conditions like dysmenorrhea and PMS. We also uncover the complexities of andropause in males and address the various symptoms and treatment options available.


Learn more at drknews.com

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com


00:00 Female and male hormone transition patterns summarized.

08:51 BMI impacts endocrine system, genetic factors matter.

12:40 Excessive estrogen production causes gynecomastia in men.

18:51 Prostaglandins influence menstrual pain and discomfort.

26:21 Causes of heavy or light menstrual bleeding.

32:24 High DHE and testosterone levels suggest PCOS.

33:24 PCOS symptoms can normalize with metabolic control.

38:45 PCOS pathophysiology, treatment, and clinical manifestations.

45:19 Adrenal glands help manage perimenopausal symptoms.

49:33 Hormonal changes in perimenopause cause inflammatory response.

59:03 Inflammation and hormones affect women's health.

01:03:18 Menopause can worsen underlying health conditions.

01:06:44 Adulthood: decline in male function and symptoms.

01:13:49 LH levels range indicates potential hormone balance.

01:16:27 Free testosterone is crucial, especially as we age.

01:25:04 Normal range testosterone, relative hypogonad men, DHT.

01:27:26 Male and female hormone disorders patterns explained.



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1 year ago
1 hour 29 minutes 48 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 40: Hormone Balancing through Gut Health

In this episode, Dr. Kharrazian delves into the world of hormone imbalances, microbiome diversity, and the impact of polyphenols and phytoestrogens. He discusses evidence-based strategies for autoimmune disease, brain health issues, and chronic health conditions, and sheds light on the pivotal role of gut health in estrogen metabolism. He also addresses nutraceutical support for insulin resistance and regulating testosterone.

 

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


00:00 Transitioning off HRT may benefit from modulators.

06:05 Flavonoids affect estrogen receptor, 4 key foods.

10:05 Healthy microbiome diversity enhances effectiveness of soy products.

11:16 Carbs impact conversion of phytoestrogens efficiently.

16:29 Gut health crucial for managing estrogen disorders.

18:57 Diet, lifestyle, supplements affect microbiome diversity.

20:53 Liver pathways detoxifying hormones, potential competition. Nutrients aid hepatic inflammation support.

26:51 Essential fatty acids are critical for health.

30:29 Prostate glands cause pelvic issues, need support.

34:19 Men's testosterone, estrogen testing, insulin resistance, obesity, blood sugar imbalances, hypoglycemia, insulin resistance, dietary guidelines.

36:02 Optimize diet to prevent blood sugar crashes.

39:41 Review found herbal medicines improve PCOS symptoms.

42:41 Aggressive protocol for PCOS using nutraceuticals.

47:19 Nutraceuticals may protect serotonin cells, boost testosterone.

50:44 Botanicals boost testosterone levels but may vary.

53:42 Glial cells switch to pro-inflammatory state. Hormone changes amplify neuroinflammation.

56:35 Peptides stimulate hormones, potential for endocrine treatment.

58:37 Dr. Kharrazian's podcast and blog information.


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1 year ago
59 minutes 42 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 39: Hormone Imbalance & Obesity

In this episode, Dr. Kharrazian provides insight into the impact of obesity on male and female hormone imbalances, infertility, and the body's endocrine system. From the role of adipose tissue to the effects of hormone replacement therapy, this episode explores the complexities of hormone balance and offers evidence-based strategies for managing these crucial aspects of health. Dr. Kharrazian discusses blood glucose management, gut health, and the impact of hormone deficiencies on mitochondrial function and other aspects of physiology.


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


Learn more at drknews.com


Timestamps:

00:00 Hormones impact mitochondria, affecting cellular function.

09:31 Mitochondrial health affects recovery and signaling pathways.

12:00 Hormone replacement may fix mitochondrial dysfunction. Stress affects mitochondria.

16:22 Certain genetic factors can increase health risks.

25:26 Aromatization causes body fat increase, vicious cycle.

31:00 Estrogen drop in women leads to fat tissue.

32:52 Steroid use can disrupt endocrine system balance.

42:35 Healthy adrenal function is crucial in perimenopause.

48:03 Adrenal gland imbalances and stress responses summarized.

53:04 Insulin resistance causes blood sugar roller coaster.

57:10 Symptom patterns indicating early stages of insulin resistance.

01:02:30 Gut bacteria convert chemicals and hormones.

01:08:19 Hormone deficiency causes leaky gut, affecting health.

01:12:26 Inflammatory diets cause low testosterone levels.

01:20:18 Hormones critical for health and disease prevention.

01:23:28 Hormone imbalances affect brain recovery and health.

01:28:20 For more info visit drknews.com/podcast.


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1 year ago
1 hour 29 minutes 43 seconds

Solving the Puzzle with Dr. Datis Kharrazian
Episode 38: Hormone Imbalance and Environmental Toxins

In today's episode, we dive into the impact of hormone imbalance on overall health. From the critical role of adequate sleep in hormone regulation to the potential effects of environmental chemicals on endocrine function, Dr. Kharrazian shares valuable insights and evidence-based strategies for managing hormone imbalances.


For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/


Learn more at drknews.com


00:00 Toxic chemicals in everyday products, impacts on health.

09:13 Endocrine disrupting chemicals impact female reproductive function.

12:57 Endocrine disrupting chemicals impact PCOS in females.

18:47 Endocrine disrupting chemicals impact serious health conditions.

22:17 Inflammation impacts male testosterone and female infertility.

32:18 Aquifers impact water supply with hormones, pharmaceuticals.

34:54 Use multiple layers of water filtering systems.

43:10 Air pollution impacts cortisol and microbiome health.

48:26 Intense exercise is important for hormonal balance.

52:57 Low or high body mass affects hormones.

58:06 Injections are crucial for male obesity issues.

01:03:36 Muscle mass affects health risks in obesity.

01:08:32 Suppressed FSH, low TSH, hormone-related issues.

01:12:27 Hormones, sleep, and strategies for better rest.

01:19:50 Minimum needed protein is 1g/lb body weight.

01:24:18 Blood sugar: Hypoglycemia vs insulin resistance management.


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1 year ago
1 hour 27 minutes 14 seconds

Solving the Puzzle with Dr. Datis Kharrazian

Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian's experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has innovated through trial and error in working with complex patient cases.

Dr. Kharrazian discusses evidence-based models incorporating diet, nutrition, and lifestyle — protocols hard won through decades of working with tough, complex patient cases. 


His goal is to help teach you effective models for so-called “mystery” symptoms and conditions so you can regain control of your health and life.


Hashimoto's: Solving the Puzzle, is a new online course from Dr. Kharrazian, who is the originator of evidence-based strategies for managing autoimmune Hashimoto's hypothyroidism. This course has the most complete and current information for managing Hashimoto's available.


You can find more information at drknews.com.

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.