📖 Episode Description Welcome back to the Byolete Podcast, where we break down the science behind our brand. In this special episode, we take you inside our launch event — a huge milestone for Byolete. We share what it meant to us, the highlights from the day, and the excitement of officially bringing our mission to life. We explore: The vision behind hosting our launch event Key moments and takeaways from the day The people and community that made it possible What’s next for Byolete as we grow from here This is a conversation about celebration, gratitude, and the beginning of an exciting journey for Byolete and our community. 🌐 Discover Byolete’s Products & ServicesLearn more about our tests, consultations, and preventative health tools at www.byolete.co.uk. 📲 Follow Us on InstagramBrand: @ByoleteJessica: @healthwithjessica_Lee: @leesmithfitness ⚠️ DisclaimerThis podcast is for educational purposes only and does not constitute medical advice. Please consult a healthcare professional before making any health-related decisions.

📖 Episode Description Welcome back to the Byolete Podcast, where we break down the science behind our brand. In this episode, we go back to where it all began — why we started Byolete. We share the motivations, challenges, and “aha” moments that shaped our vision for the company. We explore: What sparked the idea to create Byolete The early challenges that tested our resolve How our personal experiences shaped our approach to healthcare The core values that guide everything we do today This is a conversation about our journey, the “why” behind our work, and the mission that drives us to make a real impact in people’s health. 🌐 Discover Byolete’s Products & ServicesLearn more about our tests, consultations, and preventative health tools at www.byolete.co.uk. 📲 Follow Us on InstagramBrand: @ByoleteJessica: @healthwithjessica_Lee: @leesmithfitness ⚠️ DisclaimerThis podcast is for educational purposes only and does not constitute medical advice. Please consult a healthcare professional before making any health-related decisions.

📖 Episode Description Welcome back to the Byolete Podcast, where we break down the science behind our brand and challenge the status quo in healthcare. In this episode, we discuss insulin resistance — often labelled as a blood sugar problem, but in reality, it's a disease of fat metabolism. We explore: Why insulin resistance begins long before blood glucose rises How dysfunctional fat storage is the root cause The limitations of relying solely on fasting glucose and HbA1c for early detection How a proactive approach to metabolic health can prevent chronic disease years in advance This is a conversation about rethinking insulin resistance, reframing metabolic health, and addressing the problem at its root cause — fat metabolism. 🌐 Discover Byolete’s Products & ServicesLearn more about our tests, consultations, and preventative health tools at www.byolete.co.uk. 📲 Follow Us on InstagramBrand: @ByoleteJessica: @healthwithjessica_Lee: @leesmithfitness ⚠️ DisclaimerThis podcast is for educational purposes only and does not constitute medical advice. Please consult a healthcare professional before making any health-related decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we question the widespread use of the 10-year cardiovascular risk calculator — the same tool used in nearly every GP surgery to decide when (and if) to intervene. But if we know cardiovascular disease begins decades before diagnosis, why are we waiting so long to act? We explore how these risk scores overlook younger individuals, fail to account for key biomarkers, and reinforce a system that reacts to illness instead of preventing it. This is a conversation about rethinking risk, redefining prevention, and building a better model for long-term health. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, a patient’s question about statins sparks a much bigger discussion: why do we wait for disease before taking action? We explore how the current healthcare system is designed to treat illness, not prevent it — and why proactive monitoring, individualised data, and early intervention could change everything. This episode lays out the case for a new model of preventative health — one where we track our internal health before symptoms appear, and use that insight to stay well for longer. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we challenge the long-held idea of "bad cholesterol." We break down why LDL cholesterol alone is a poor predictor of cardiovascular risk, and explain why ApoB gives a far clearer picture of what's happening beneath the surface. We also unpack the fact that all cholesterol is the same molecule — and that the terms “good” and “bad” are overly simplistic. If you've ever been told your cholesterol is “normal” or “high,” this episode will give you the nuance that traditional tests often miss. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we shine a light on Lipoprotein(a) — a genetically determined lipid marker that’s often missed in routine testing but plays a major role in cardiovascular disease risk. We explain what Lp(a) is, how it differs from LDL cholesterol, why it's not affected by lifestyle or statins, and what options are emerging for those with elevated levels. If you’ve never heard of Lp(a), or don’t know if you’ve been tested, this is one you won’t want to miss. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we explore a fascinating case study (adapted from Peter Attia) where a patient with low muscle mass presented with unexpected insulin resistance — despite appearing healthy. We highlight why traditional tests often miss metabolic dysfunction, and how tools like the oral glucose tolerance test (OGTT) can reveal problems that fasting glucose and HbA1c can’t. This episode emphasises the need for frequent, dynamic monitoring, especially in individuals who may seem well on the surface but are metabolically at risk. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we break down the 10 most prescribed medications in the UK and highlight how 9 out of 10 are used to treat preventable conditions — from cardiovascular disease to type 2 diabetes and lifestyle-related deficiencies. We explore what each drug does, why it’s prescribed so frequently, and how simple, targeted lifestyle interventions could reduce reliance on medication. This episode reinforces why our approach at Byolete focuses on prevention before prescriptions. ⏱️ Timestamps: 00:00 – Introduction02:30 – Sertraline07:10 – Metformin11:40 – Vitamin D14:21 – Bisoprolol15:53 – Levothyroxine19:14 – Ramipril20:35 – Lansoprazole and Omeprazole27:21 – Amlodipine28:45 – Atorvastatin34:54 – Final thoughts 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we break down insulin resistance — a condition that often goes undetected for up to a decade before type 2 diabetes is diagnosed. Despite its subtle presentation, insulin resistance is at the root of many chronic conditions, including cardiovascular disease, non-alcoholic fatty liver disease (NAFLD), and even certain cancers. We explain the underlying mechanism, why routine check-ups often miss it, and why it's a central biomarker in our preventative health strategy. This episode lays the foundation for future discussions as we explore how insulin resistance connects to other markers on the Byolete panel. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. This episode dives into the underestimated role of triglycerides in cardiovascular disease. Once seen as a secondary marker, triglycerides are now recognised as a major contributor to cardiovascular risk — primarily through their effect on Apo B particle numbers and the formation of atherogenic lipoproteins. We explain how elevated triglycerides may reflect insulin resistance, how they relate to post-meal metabolism, and why we include them in the Byolete blood panel. Plus, we share our own triglyceride levels and what they reveal about our metabolic health. ⏱️ Timestamps: Introduction – 00:00Why triglycerides are an important marker – 05:49 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we unpack Apolipoprotein B (Apo B) — one of the most powerful predictors of cardiovascular risk that most people have never heard of. We explain what Apo B actually measures, how it differs from traditional cholesterol tests, the clinical relevance of particle number versus size and why it is included in the Byolete blood panel. If you’re serious about longevity and heart health, this episode is essential listening.   🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools.   📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness   ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this episode, we break down HbA1c — a key marker of long-term blood sugar control and metabolic health. We explain what HbA1c actually measures, why it's included in the Byolete testing panel, and how it can uncover early signs of insulin resistance, prediabetes, or metabolic dysfunction before symptoms even appear. We also dive into the official reference ranges, what they mean in practice, and share our personal HbA1c results — including how lifestyle, diet, and genetics influence them. If you're training hard but ignoring your blood sugar, this episode is for you. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for educational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

📖 Description: Welcome back to the Byolete podcast, where we discuss the science behind the brand. In this first episode, we share the personal and professional reasons why we created Byolete — a preventative health brand built on science, data, and a deep passion for longevity. You'll hear about our backgrounds in pharmacy and fitness, our own health journeys (including managing a genetic form of diabetes), and why we believe modern health needs a shift toward internal health metrics, not just aesthetics. We also talk about where Byolete is headed — from advanced blood testing to education that empowers individuals to take ownership of their health. 🌐 Explore Our Products & Services: Visit www.byolete.co.uk to learn more about our tests, consultations, and preventative health tools. 📲 Follow Us on Instagram: Brand: @Byolete Jessica: @healthwithjessica_ Lee: @leesmithfitness ⚠️ Disclaimer: This podcast is for informational purposes only. It does not replace medical advice. Always consult with a healthcare professional before making health decisions.

Stay tuned for our upcoming business launch, we will be releasing more details across our social media platforms...   https://www.instagram.com/byolete/profilecard/?igsh=MXdkYTFtYTM3emE4MQ==

Welcome to The Chemist Couple podcast! The National Health Service (NHS) has been the backbone of UK healthcare since 1948, but is it on the brink of collapse? 📉 With rising demand, financial strain, and increasing wait times, we explore whether our generation could be the last to access free healthcare at the point of need. From funding breakdowns to private healthcare costs, we dive deep into what’s really happening with the NHS and what we can do to save it.   ⏱️ Timestamps:   *00:00 - Why discuss the NHS healthcare model? *02:17 - How is the NHS funded and how are these funds allocated? *04:02 - The difficulty in using the NHS properly *06:41 - Are more people using A&E now? *07:28 - How much do NHS services cost the taxpayer? *11:10 - Why are waiting times high in the NHS? *17:08 - Private healthcare cost examples | Pregnancy | Doctor reviews | Medication | Investigations *22:28 - Correct use of NHS examples *24:48 - Incorrect use of NHS examples *33:12 - How to select the correct NHS service | Utilise your pharmacist *37:49 - Utilising preventative health will save the NHS *41:57 - What conditions cause people to be ‘economically inactive’? *44:39 - How the NHS could look in the future *46:44 - Final thoughts   🔔 Subscribe to The Chemist Couple Podcast: Stay on top of the latest science-based preventative health tips. Hit the like button and tell us: What do you think is the biggest challenge facing the NHS today?#NHS #HealthcareCrisis #UKHealthcare #PreventativeHealth #TheChemistCouplePodcast   🎙️ Listen to our podcast: Spotify 🎧: The Chemist Couple PodcastApple Podcasts 🍏: The Chemist Couple Podcast 📩 Sign up for our newsletter to learn how we personally apply science to enhance our lifestyle: Join Here 📺 Watch this episode on YouTube: The Chemist Couple Podcast   📚 Studies & Data Referenced in This Episode:   * Office for National Statistics: Rising ill health and economic inactivity in the UK (2019-2023) – Read Here * NHS England: Making the case for a personalised approach – Read Here * The King’s Fund: Key facts & figures on NHS spending – Read Here * NHS Confederation: Autumn Budget 2024 – What You Need to Know – Read Here * NHS Data Report on Healthcare Spending & Service Demand – Read Here ⚠️ Disclaimer: This podcast is for informational purposes only and should not replace advice from a healthcare professional. If you have any questions, reach out to us. Thanks for watching!

Welcome to The Chemist Couple podcast! VO₂ max is one of the strongest predictors of longevity, but why does it matter? 🚀 We break down the science behind VO₂ max, why maintaining it is crucial, and how you can improve it to enhance your health and lifespan. Don't miss these key insights! ⏱️ Timestamps: 00:00 - Why have we chosen VO₂ max? | Longevity links05:29 - What is VO₂ max? | Why do you need to maintain a high VO₂ max?09:33 - Can you improve your VO₂ max?12:07 - Why do people have a low VO₂ max?15:48 - How can you increase VO₂ max?21:16 - How to test your VO₂ max?25:05 - When should you start optimising your VO₂ max?29:48 - VO₂ max key points   🔔 Subscribe to The Chemist Couple Podcast:Stay on top of the latest science-based preventative health tips. Hit the like button and tell us: Have you ever tested your VO₂ max?#VO2Max #Longevity #CardiorespiratoryFitness #HealthOptimization #TheChemistCouplePodcast 🎙️ Listen to our podcast:Spotify 🎧: The Chemist Couple PodcastApple Podcasts 🍏: The Chemist Couple Podcast 📩 Sign up for our newsletter to learn how we personally apply science to enhance our lifestyle: Join Here 📺 Watch this episode on YouTube: The Chemist Couple Podcast   📚 Studies Referenced in This Episode: "Survival of the fittest: VO₂ max, a key predictor of longevity" – Strasser & Burtscher, Frontiers in Bioscience (2018) "VO₂ max as an indicator of health and fitness" – National Library of Medicine ⚠️ Disclaimer: This podcast is for informational purposes only and should not replace advice from a healthcare professional. If you have any questions, reach out to us. Thanks for watching!

Welcome to The Chemist Couple podcast! With GLP-1 medications like Mounjaro becoming more popular, are we overlooking the risks? From potential nutrient deficiencies to serious health concerns like pancreatitis and diabetic retinopathy, we break it all down. Don't let the hype overshadow the science! ⚠️   ⏱️ Timestamps:   00:00 - The Rise of GLP-1s: Why Are They So Popular? 01:56 - Eating Less = Harm? The Hidden Risks 03:43 - Losing Lean Mass: What You Need to Know 04:55 - The Risk of Vitamin Deficiencies 05:58 - Can You Keep the Weight Off? Leptin Explained 07:51 - Lifestyle Changes: Key to Long-Term Success 10:18 - The ‘Golden Dose’: A Dangerous Shortcut? 11:57 - ‘Microdosing’ GLP-1s: Risky & Unlicensed! 14:31 - Surgery & Aspiration: A New GLP-1 Warning 18:36 - Just How Powerful Are GLP-1s? 19:32 - Diabetic Retinopathy: An Overlooked Side Effect 22:05 - Pancreatitis: A Rare but Serious Risk 23:55 - Fertility, Pregnancy & Breastfeeding: What’s Safe? 29:20 - Planning a Pregnancy? Here’s What to Consider 30:21 - Final Thoughts: Are GLP-1s Worth the Risk?   🔔 Subscribe to The Chemist Couple Podcast: Stay on top of the latest science-based preventative health tips. Hit the like button and tell us: What are your thoughts on GLP-1 medication?   🎙️ Listen to our podcast: Spotify 🎧: The Chemist Couple PodcastApple Podcasts 🍏: The Chemist Couple Podcast 📩 Sign up for our newsletter to learn how we personally apply science to enhance our lifestyle: Join Here 📺 Watch this episode on YouTube: The Chemist Couple Podcast   📚 Studies Referenced in This Episode:   Guyton & Hall Medical Physiology (14th Edition) – General physiology overview Rang & Dale’s Pharmacology (10th Edition) – General pharmacological overview Electronic Medicines Compendium (EMC): Mounjaro (tirzepatide) Summary of Product Characteristics – Read Here Diabetes & Primary Care, Vol 23 No 4 (2021): GLP-1 receptor agonists and diabetic retinopathy – Read Here ⚠️ Disclaimer: This podcast is for informational purposes only and should not replace advice from a healthcare professional. If you have any questions, reach out to us. Thanks for watching!  

Welcome to The Chemist Couple podcast! Is your daily coffee fix affecting your heart? ☕ In this bite-sized episode of The Chemist Couple Podcast, we break down the science behind caffeine’s effects on blood pressure, heart rate, and sleep. 🚀   🔬 Key Takeaways: ✔️ Caffeine blocks adenosine, leading to increased heart rate & blood pressure. ✔️ Safe daily intake: ≤400mg (per the Food and Drug Administration). ✔️ If you have hypertension or heart issues, caffeine might not be ideal. ✔️ It can reduce REM sleep and stay in your system for up to 12 hours! ✔️ Coffee isn’t just caffeine—it’s packed with polyphenols & gut-friendly compounds!   🔍 Episode Breakdown:   * 00:00 - bitesize introduction * 00:23 - What is caffeine? * 00:40 - What are the common sources of caffeine? * 01:08 - What is a safe dose? * 01:34 - How does caffeine affect blood pressure? * 02:26 - How does caffeine affect heart rate? * 03:13 - How does caffeine affect sleep? * 04:15 - Caffeine vs coffee   🔔 Subscribe to The Chemist Couple Podcast:Stay on top of the latest science-based preventative health tips. Hit the like button and tell us: How does caffeine fit into your life?   🎯 Our Takeaway? Stick to ≤400mg/day, avoid caffeine after 12 PM, and opt for decaf if you love the taste!   As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening!   Here is a list of the sources that we used to make this podcast: https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehae871/7928425?login=false - Coffee timing and mortality https://link.springer.com/article/10.1007/s12170-024-00735-8#Sec4 - Pre-workout studies on CVD https://pmc.ncbi.nlm.nih.gov/articles/PMC9939061/- Coffee increasing CVD mortality https://www.sciencedirect.com/science/article/pii/S0273230017302210#abs0015 - Caffeine and cardiovascular health report https://www.sciencedirect.com/science/article/pii/S0273230017302210#sec1 - Caffeine and CVD overview https://www.sciencedirect.com/science/article/pii/S0278691517301709#sec3 - Safe dosing of caffeine Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

Welcome to The Chemist Couple podcast! Are your daily cups of coffee helping or hurting your heart? In this episode, we break down how caffeine affects blood pressure, heart rate, and cardiovascular health, helping you enjoy caffeine wisely without risking your well-being. Whether you're a coffee lover or pre-workout fan, you'll walk away with actionable tips to protect your heart.   🔍 Episode Breakdown: 00:00 Why caffeine and cardiovascular health matter 01:27 What is caffeine? How it blocks adenosine 02:40 Hidden sources of caffeine (it’s not just coffee!) 05:50 What is the toxic dose of caffeine? How your body metabolises it 08:06 What research says about caffeine and heart health 09:18 Coffee vs energy drinks: Does the source matter? 10:18 Is decaf coffee still good for you? 11:40 How caffeine affects blood pressure 16:36 What is a safe daily dose of caffeine? 17:55 When to have caffeine for better heart health 19:50 Caffeine's impact on heart rate and risk of arrhythmias 28:15 How caffeine affects with your sleep 30:40 Is pre-workout harming your cardiovascular system? 33:25 How we’re adjusting our caffeine intake   What You’ll Learn: The surprising relationship between caffeine and heart disease How much caffeine is really safe for your heart Best practices for enjoying caffeine without disrupting sleep or fitness goals   🔔 Subscribe to The Chemist Couple Podcast:Stay on top of the latest science-based preventative health tips. Hit the like button and tell us: How does caffeine fit into your life? #CaffeineHealth #HeartHealth #CoffeeEffects #BloodPressure #HeartRate #ChemistCouplePodcast #HealthyLiving #CaffeineTips   Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA   https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678   Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast   You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q    As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening!   Here is a list of the sources that we used to make this podcast:   https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehae871/7928425?login=false - Coffee timing and mortality https://link.springer.com/article/10.1007/s12170-024-00735-8#Sec4 - Pre-workout studies on CVD https://pmc.ncbi.nlm.nih.gov/articles/PMC9939061/- Coffee increasing CVD mortality https://www.sciencedirect.com/science/article/pii/S0273230017302210#abs0015 - Caffeine and cardiovascular health report https://www.sciencedirect.com/science/article/pii/S0273230017302210#sec1 - Caffeine and CVD overview https://www.sciencedirect.com/science/article/pii/S0278691517301709#sec3 - Safe dosing of caffeine   Guyton & Hall Medical Physiology 14th edition- general physiology overview   Rang & Dale’s Pharmacology 10th edition - general pharmacological overview