Join Joe Cohen and gerontologist Zora Benhamou, host of the Hack My Age podcast, as they discuss biohacking for women's health, anti-aging, and menopause.
Zora shares her personal experiences and professional insights on topics like the importance of tracking hormones, testing for optimal health, the impact of lifestyle choices, and the use of supplements and alternative therapies. They also discuss the effects of thyroid hormones and the controversial yet effective use of Botox.
Learn actionable tips to optimize your body and mind at any age.
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Timestamps:
00:00 Introduction to the Joe Cohen Show
00:16 Meet Zora Bemo: Gerontologist and Biohacker
00:34 Biohacking and Women's Health
02:26 The Importance of Hormone Tracking
03:35 Joe's Early Biohacking Journey
05:48 The Role of Lab Testing in Biohacking
21:38 Hormone Testing and Menopause
45:47 The Importance of Early Health Preservation
46:15 Botox: Personal Experiences and Opinions
46:25 The Taboo of Botox in the Health World
50:53 Cultural Perspectives on Skincare
52:10 Longevity and Healthy Aging Tips
53:24 Favorite Supplements and Their Effects
55:09 The Role of Serotonin and Sleep
01:00:27 Final Thoughts and Where to Find More
Join Joe Cohen on The Joe Cohen Show as he speaks with Dr. Chris Shade, founder and CEO of Quicksilver Scientific.
In this insightful episode, they dive deep into the world of biohacking, detoxification, and the science behind liposomal supplements. Dr. Shade explains the intricacies of mercury detox, the role of glutathione, the benefits of liposomal delivery systems, and how certain supplements can optimize health.
They also discuss the challenges of current detoxification methods and the incredible advancements in the field, including liposomal technology for enhanced absorption and effectiveness.
This episode is a must-watch for anyone interested in cutting-edge health optimization techniques.
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Timestamps:
(00:00) Introduction to the Joe Cohen Show
(00:17) Meet Dr. Chris Shade
(01:24) The Journey to Healthcare and Detoxification
(02:40) Understanding Liposomes and Their Importance
(05:19) Challenges in Liposomal Supplementation
(10:38) Comparing Glutathione and NAC
(14:37) The Power of Liposomal Delivery Systems
(34:43) Detoxification and Mercury Testing
(37:38) Understanding Mercury Detoxification
(37:52) The Role of Glutathione in Detox
(38:30) Detoxification Protocols and Binders
(39:24) Urine Testing and Mercury Measurement
(39:53) Challenge Testing and Its Limitations
(43:30) Kidney and Liver Function in Detox
(53:07) The Importance of NRF2 Upregulation
(57:52) The Role of Bile Flow in Detox
(01:00:12) Advanced Detoxification Techniques
(01:08:03) Microplastics and Plasma Exchange
(01:10:34) Where to Find Detox Products
Joe Cohen talks with Dr. Ben Weitz, a functional medicine practitioner with over 35 years of experience, about his approach to addressing gut health and autoimmune conditions.
Ben explains how functional medicine focuses on finding and treating root causes, such as diet, lifestyle, microbiome imbalances, and chronic infections, rather than just managing symptoms.
They discuss how conditions like IBS and autoimmune diseases are connected to factors like food sensitivities, toxins, and gut health, and explore various testing methods and treatment strategies.
Ben also shares practical insights from his clinical practice and ongoing work in the functional medicine community.
Tune in to learn how functional medicine practitioners approach complex health issues and what steps you can take to support your gut and immune health.
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Timestamps:(00:00) Introduction
(00:16) Meet Functional Medicine Practitioner Dr. Ben Weitz
(01:20) Understanding Functional Medicine
(02:03) Exploring Gut Health and IBS
(05:09) Autoimmune Diseases: Functional vs. Conventional Medicine
(09:40) Case Studies and Practical Applications
(12:21) Debating the Validity of Functional Medicine Tests
(19:12) Understanding Histidine and Folate Correlation
(20:00) Critique of Biochemical Assumptions in Testing
(21:01) Genetic Conditions and Functional Medicine Tests
(23:02) Protein Consumption and Metabolite Variability
(23:19) Legitimate Tests and Their Validity
(27:37) Stool Testing and Gut Health
(30:54) Addressing Autoimmune Diseases and Chronic Infections
(35:59) Conclusion
Joe sits down with Christian Drapeau, a stem cell expert with over 20 years of research under his belt, to talk about how the body repairs itself, and how we can help it do a better job.
They get into what stem cells actually do, why we lose them as we age, and how that affects recovery, energy, and long-term health. Christian shares simple, natural ways to support stem cell activity, like fasting, exercise, and plant-based supplements.
They also talk about stem cell therapies and how they compare to everyday strategies you can use to support your body’s natural repair system.
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Timestamps:
(00:00) Introduction to the Joe Cohen Show
(00:17) Meet Christian Drapeau
(01:14) Understanding Stem Cells and Their Benefits
(02:00) Natural Ways to Increase Stem Cells
(06:44) Stem Cells and Longevity
(12:19) Stem Cell Supplements vs. Injections
(23:42) Hyperbaric Chambers and Stem Cells
(25:32) Understanding Hyperbaric Chambers
(26:45) Introduction to Stem Cell Enhancing Plants
(27:13) Top Plants for Increasing Stem Cells
(28:00) Mechanisms and Effects of Specific Plants
(32:45) Combining Plants for Optimal Stem Cell Release
(34:35) Active Compounds in Stem Cell Enhancing Plants
(41:59) Stem Cell Supplements and Their Benefits
(46:08) Conclusion and Further Resources
In this episode of The Joe Cohen Show, Joe takes a personal and scientific look at monogamy, exploring why some people feel more content in exclusive relationships than others.
He breaks down what research says about the hormone vasopressin and its role in bonding, loyalty, and long-term attachment, drawing from both animal studies and genetic findings.
Joe also shares a surprising result from his own supplement routine, where taking L-arginine and glycine seemed to shift his natural tendencies toward greater monogamy.
It's a unique mix of biohacking, hormones, and human behavior you won’t want to miss.
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Timestamps:
(00:00) Introduction to the Joe Cohen Show
(00:16) Exploring Monogamy and Personal Tendencies
(02:56) The Role of Vasopressin in Monogamy
(05:44) Vasopressin's Impact on Human Relationships
(14:14) Personal Experiment with Supplements
(22:42) Conclusion and Recommendations
In this special episode, Joe sits down with health coach and SelfDecode Pro user Joline Schaaphok to walk through her personalized health insights using genetic data.
They explore everything from supplement recommendations and food sensitivities to overlooked risk factors like anemia and cardiovascular health. It’s a real-time example of how genetic reports, labs, and lifestyle data can work together to uncover actionable insights.
Whether you're a practitioner, a biohacker, or just curious about precision health, this live analysis offers a behind-the-scenes look at how to turn data into meaningful change.
- Check out SelfDecode: https://selfdecode.com/
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Timestamps:
(00:00) Introduction to the Joe Cohen Show
(00:16) Meet Joline Schaaphok
(02:02) Diving into Joline's Genetic Results
(03:32) Macronutrient and Vitamin Recommendations
(04:41) Food Sensitivities and Allergies
(05:46) Health Overview Report: Genetic and Lifestyle Insights
(09:27) Supplement Recommendations and Customization
(23:29) Refining the Supplement List
(24:08) Optimizing the Daily Regimen
(25:29) Detailed Regimen Breakdown
(28:15) Advanced Filtering Techniques
(33:11) Addressing Anemia and Food Allergies
(39:17) Comprehensive Lab Testing
(40:50) Genetic Insights and Recommendations
(43:10) Final Thoughts and Next Steps
In this episode of the Joe Cohen Show, host Joe Cohen discusses the power of biohacking and precision health with Sasha Powell, a nurse practitioner and integrative healthcare provider.
Sasha shares her experience using DNA data to optimize her patients' health outcomes, focusing on areas like hormone and weight management, mental health, and overall well-being. They dive into the specifics of how genetic insights can personalize treatment plans, leading to better, faster results.
Whether it's diagnosing mental health issues more accurately or managing physical health conditions like diabetes and inflammation, Sasha highlights the transformative impact of personalized medicine.
Tune in to understand why integrating genetic information into healthcare is not just an innovation but a necessity.
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Timestamp:
(00:00) - Introduction to the Joe Cohen Show
(00:16) - Meet Sasha Powell
(00:56) - Using DNA for Personalized Health Solutions
(01:24) - Weight and Hormone Management Strategies
(03:11) - Blood Sugar Regulation and Diet Recommendations
(07:25) - Mental Health and Genetic Insights
(10:59) - The Role of Neurochemistry in Treatment Plans
(13:48) - Personalized Supplement Recommendations
(30:10) - The Importance of Methylation in Health
(34:03) - Utilizing Self Decode for Comprehensive Health Management
(38:31) - Optimizing Quality of Life
(39:06) - Longevity Screener Insights
(39:34) - Clinical Overview Report
(40:30) - Health Overview Report
(41:44) - Lab Data and Clinical Recommendations
(45:15) - Family Planning and Genetic Risks
(45:57) - Integrating Lab Tests and Genetic Data
(48:44) - Using SelfDecode in Clinical Practice
(58:56) - The Future of Healthcare with AI
(01:04:26) - Organic Acids Test and Lab Considerations
(01:08:08) - Concluding Thoughts and Recommendations
In this solo episode, Joe Cohen explores the powerful effects of glutamate on the brain and how elevated levels can drive anxiety, obsessive thoughts, and overstimulation.
He shares insights from personal experiments with supplements like AKG, proline, and arginine and explains how they impacted his mental state, motivation, and focus.
Joe also breaks down the symptoms tied to excess glutamate, from headaches and insomnia to mood swings and neurological issues. He discusses why certain people are more sensitive to glutamate due to genetic differences, and outlines what’s helped him manage it, including specific doses of NAC, glycine, B6, vitamin C, and more.
This episode offers a practical, firsthand look at how glutamate functions, what throws it out of balance, and what can be done to bring it under control.
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Timestamps:
(00:00) - Introduction
(00:16) - Understanding Glutamate and Its Effects
(04:32) - Personal Experiments with Glutamate
(08:22) - Supplements and Strategies to Lower Glutamate
(18:31) - Symptoms and Conditions Related to High Glutamate
(20:20) - Genetic Factors and Glutamate
(22:13) - Conclusion
In this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing.
Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims being sold to consumers.
Krishnan, the mind behind one of the few microbiome platforms used in published research, breaks down what a legitimate test looks like and why most tests on the market fall short, sometimes by as much as 70% in accuracy.
The conversation also explores probiotics in depth, why strain specificity matters, and how consumers can make more informed decisions when navigating this complex and evolving space.
Whether you’re a health professional or someone trying to optimize your gut, this episode will help you separate science from sales.
📌 Topics covered: microbiome testing technology, bioinformatics, probiotic strains, sequencing methods, red flags in wellness tech
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(00:00) - Introduction to the Joe Cohen Show
(00:16) - Meet Kiran Krishnan
(01:07) - Understanding Microbiome Testing
(03:01) - The Importance of Whole Genome Sequencing
(04:48) - Challenges in Microbiome and Genetic Testing
(05:42) - Critique of 16S Ribosomal RNA Sequencing
(11:58) - Issues with Viome and Other Testing Companies
(21:14) - Complexities of Microbiome Mapping
(23:27) - Validating Microbiome Tests
(27:04) - The Future of Microbiome Technology
(28:10) - Advancements in Genome Sequencing
(29:18) - Challenges in Microbiome Analysis
(30:40) - Economic Realities of Sequencing
(31:57) - Company Strategies and Ethics
(33:49) - Benefits of Microbiome Testing
(35:12) - Probiotics and Gut Health
(38:20) - Top Probiotic Strains
(43:00) - Importance of Specific Strains
(52:52) - Concluding Thoughts on Probiotics
Most genetic testing companies promise personalized health insights, but their reports barely scratch the surface, often analyzing just a handful of genetic variants.
In this episode, Joe Cohen shares what happened when the SelfDecode team took a close look at dozens of these reports to understand how and why they fall short and what it actually takes to do it right.
He shares how SelfDecode analyzes hundreds of thousands (sometimes millions) of variants per report, uses advanced technology to generate more accurate results, and integrates labs and lifestyle data to deliver truly actionable recommendations.
If you've ever wondered whether your DNA test was worth the money, this episode is a must-listen.
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- Check out SelfDecode: https://selfdecode.com/
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(00:00) - Introduction
(00:16) - Overview of Genetic Reports
(01:26) - Competitor Analysis and 100X Series
(02:34) - Detailed Breakdown of Genetic Reports
(03:27) - Recreating Competitor Reports
(08:57) - Final Thoughts
In this episode, Joe Cohen talks with Mark Notton, founder of Revive DNA, about how your DNA can shape your sleep, energy, and long-term health.
After helping his wife recover from a chronic autoimmune condition using a personalized nutrition approach, Mark left his executive career at Samsung to launch a health tech company.
Now, Revive DNA is making science-backed, DNA-driven wellness accessible to more people with support from major institutions and powered by OmicsEdge technology.
Tune in for a deep dive into the future of personalized health and what most programs are still getting wrong.
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Timestamps:
(00:00) - Introduction
(00:16) - Meet Mark Noten: Founder of Revive DNA
(01:06) - Mark's Journey into the Health Space
(02:09) - A Personal Health Crisis: Mark's Wife's Story
(04:40) - The Role of DNA in Health and Nutrition
(06:44) - Revive DNA: Technology and Partnerships
(11:53) - Revive DNA App: Features and Benefits
(19:31) - Upcoming Sleep Study with Samsung
(28:43) - Future Directions and Closing Remarks
In this episode, Joe discusses the benefits of the probiotic L. Plantarum, specifically the 299V strain. He talks about its effectiveness in reducing gas, improving mood, exercise recovery, and more.
He shares how he personalizes his probiotic routine using SelfDecode, why the specific strain matters more than the brand, and how he takes higher doses to really feel a difference. If you're dealing with gut issues or just want to understand how probiotics can affect things like immunity, allergies, mood, or even homocysteine levels, there’s a lot in here you’ll find useful.
Tune in to learn more about optimizing your health with probiotics and get personalized recommendations from SelfDecode.
- Check out SelfDecode: https://selfdecode.com/
- Join Joe’s online community: https://thejoecohenshow.com/
Timestamps:
(00:00) - Introduction
(00:16) - Discussing L. Plantarum and Probiotic Recommendations
(01:28) - Joe’s Personal Experiences with Probiotics
(05:28) - Benefits of L. Plantarum
(07:43) - Research and Evidence on L. Plantarum
(09:56) - L. Plantarum's Impact on Various Health Conditions
(12:01) - Probiotics and Skin Health
(13:56) - Probiotics and Metabolic Health
(18:56) - Final Thoughts and Recommendations
Join Joe Cohen in this insightful episode as he interviews Martin Kremmer, CEO and co-founder of BioWatch and FreeAge. Martin, a pioneer in the Danish biohacking scene, shares his company's innovative approach to DNA and epigenetic testing to develop personalized longevity plans.
They discuss the importance of combining different types of data, the future of functional health, and the role of stress management in achieving optimal health. Martin also introduces the Copenhagen Health Week and emphasizes the significance of simple lifestyle changes for long-term health.
Don't miss this comprehensive talk on biohacking, health tech, and much more.
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Is Bryan Johnson’s anti-aging regimen the ultimate blueprint for health, or just another one-size-fits-all approach? In this episode, Joe Cohen breaks down Johnson’s protocol, highlighting what works, what doesn’t, and why personalization is key.
Joe shares his own experiences and expert insights to help you optimize your health on your own terms.
- Discover the pros and cons of Bryan Johnson’s approach
- Why personalization matters more than a strict regimen
- The best practices for sleep, nutrition, and longevity
Join us for a deep dive into the science behind health optimization!
- Check out SelfDecode: https://selfdecode.com/
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Timestamps:
(00:20) - Brian Johnson's Blueprint: An Overview
(00:48) - Personalization in Health Protocols
(01:04) - Sleep and Eating Habits
(03:31) - Critique of Calorie Restriction
(05:10) - Protein Intake and Muscle Building
(08:20) - Skepticism on Brian Johnson's Regimen
(15:50) - Supplement Analysis: Ingredients and Dosages
(25:31) - Joe's Personal Supplement Routine
(28:21) - Blueprint Product Reviews
(32:43) - Evaluating Niacin and B Vitamins
(34:21) - Zinc, Selenium, and Genetic Predispositions
(35:21) - Personal Dosage Preferences
(37:03) - Critique of Supplement Formulas
(37:42) - Advanced Supplements and Personal Experiences
(54:50) - Dietary Choices and Sensitivities
(57:29) - Exercise and Lifestyle Recommendations
In this episode, Joe Cohen sits down with Dr. Brigitte Hanly, CEO, Chief Scientist, and co-founder of Stemaid Institute, to explore the cutting-edge world of stem cell therapy.
They discuss how pluripotent stem cells and exosomes can optimize health, repair injuries, and even slow aging. Joe shares his firsthand experience with the treatments, including their impact on immune function, brain health, and inflammation. Plus, they dive into the ethics of stem cell research and the future of regenerative medicine.
If you’re curious about biohacking, longevity, and the science behind cellular rejuvenation, this is an episode you don’t want to miss!
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Can a single probiotic strain transform your gut, lower cholesterol, and even help with food sensitivities?
In this episode of The Joe Cohen Show, we dive into the fascinating research behind Lactobacillus reuteri. Joe shares his personal experiments and breaks down the science on how L. reuteri may support digestion, reduce inflammation, and even impact weight and skin health.
Should you add this probiotic to your regimen? Tune in to find out!
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Dr. Elena Gross joins Joe Cohen to share her journey from debilitating chronic migraines to becoming a neuroscience researcher and entrepreneur.
They explore the role of mitochondrial dysfunction in migraines, how ketosis can optimize brain energy, and the importance of personalized health approaches. Joe and Elena break down the science behind oxidative stress, genetic risk factors, and key nutrients that support migraine management.
Tune in for expert insights on biohacking migraines and optimizing your brain health!
- Check out SelfDecode: https://selfdecode.com/
- Join Joe’s online community: https://thejoecohenshow.com/
Timestamps:
(04:41) - Ketosis and Heavy Metal Poisoning
(06:18) - Mitochondrial Dysfunction and Migraines
(07:27) - The Role of Neurotransmitters and Inflammation
(10:27) - Energy Deficiency and Brain Function
(22:04) - Genetic Factors and Environmental Triggers
(24:37) - Managing Migraines in Today's World
(36:25) - Understanding Migraine Triggers
(36:48) - Genetic Factors and Pathways
(37:28) - Migraine Diary and Identifying Triggers
(38:12) - Hormonal and Metabolic Influences
(38:31) - Nutritional Supplements and Ketone Bodies
(39:25) - Clinical Trials and Research Insights
(41:32) - Personal Experiences with Treatments
(42:01) - Alternative Therapies and Lifestyle Changes
(48:28) - Genetic Testing and Personalized Medicine
(57:15) - Mitochondrial Function and Chronic Conditions
In this episode of The Joe Cohen Show, Joe shares his honest review of the Genova NutrEval FMV amino acids test.
He discusses the challenges of interpreting the results, the differences between urine and blood samples, and key insights related to antioxidant support, mitochondrial function, and nutrient needs.
Considering the NutrEval test? This episode offers a detailed look at what to expect and important factors to consider.
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What if a simple technique could break down mental barriers, eliminate stress, and unlock peak performance?
Meet Brad Yates, the legendary "EFT Wizard," whose tapping techniques have transformed millions of lives.
In this episode, Joe sits down with Brad to reveal how Emotional Freedom Techniques (EFT) can help you clear emotional blocks, optimize your mindset, and take control of your well-being.
Whether you're an entrepreneur, athlete, or just someone looking to elevate your life—this episode gives you an interesting and new approach to unshakable confidence, success, and inner peace.
- Check out SelfDecode: https://selfdecode.com/l
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Are you curious about the science behind GLP-1 agonists like Ozempic? Want to know how you can naturally support weight loss and blood sugar regulation without relying on medication?
In this episode of The Joe Cohen Show, we dive deep into the world of GLP-1, exploring natural alternatives that can help suppress hunger, enhance metabolism, and optimize your health. From cutting-edge supplements to simple lifestyle tweaks, this episode is packed with actionable insights.
Tune in now to discover:
What GLP-1 agonists do and why they’re trending
The truth about their role in weight loss and diabetes management
Natural ways to stimulate GLP-1 for better health
- Check out SelfDecode: https://selfdecode.com/
- Buy Jo’s Resistant Starch: https://amzn.to/41V6gPH
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