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The Interactome
Interactome Media
41 episodes
1 week ago
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Life Sciences
Science
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All content for The Interactome is the property of Interactome Media and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
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Life Sciences
Science
Episodes (20/41)
The Interactome
Episode 39: Hurricane Season
Note: This episode was recorded on September 17, 2025. When you think of meteorology, you probably think of someone giving a weather forecast on TV. But predicting the weather requires a whole team of scientists, from those who run simulations in labs to researchers on boats, and even a few who fly planes into storms to get measurements up close. In this episode, we invite Colorado State University graduate student Delián Colón-Burgos to teach us all about forecasting hurricanes. She guides us through the field of hurricane meteorology, from what a hurricane is to how scientists are updating forecasting models to reflect our changing seas. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps: 0:00 Intro1:23 Introducing Delián!3:08 What is a Meteorologist?6:42 Seasonal Forecasting8:26 How do hurricanes get named?10:06 Delián's Origin Story13:32 Defining a Hurricane24:26 How are storms forecast?32:13 Delián's work43:57 Predictions going into hurricane season49:13 "The Calm Before the Storm"52:17 Effects of climate change on hurricanes54:35 Closing thoughts58:33 Outro
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1 week ago
59 minutes

The Interactome
Episode 38: Process Engineering
Description coming soon! Have you ever wondered how new medications go from being a research project to being safely used in hospitals and clinics around the world? In this episode of the Interactome, host Sam talks about their work on technical challenges in the field of process development. From the different types of therapeutic molecules to how horseshoe crabs keep patients safe, this episode covers many of the steps on the path between a potential medication working in a petri dish to saving lives. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:58 Biotherapeutics vs Small Molecule13:52 Research Process Lines20:24 Research Grade Pharmaceuticals vs Pharmaceutical Grade25:22 Upstream and Downstream28:47 Suspension vs Adherence of Cells40:25 Soap42:14 How do you Know if it's Safe for a Person?49:57 Clinical Trials59:50 Getting the Drug into the Person1:19:59 Conclusion
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3 months ago
1 hour 21 minutes 41 seconds

The Interactome
Episode 37: Epigenetics
The age old nature vs. nurture question is complicated, especially when genetics are involved. On this episode, we dive into the concept of “epigenetics,” which translates to “above the genome.” Joe, Sam and Natalie cover how your environment can play a role in how your genes are expressed, how you can have different kinds of cells from the same DNA, and … jello? You’ll walk away with an understanding of why your DNA is a lot more like a cook book than you think. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:04 Jean-Baptiste Lamarck6:19 Licking Rats9:55 Nature vs Nurture14:22 The Need for Epigentics20:36 The Mechanisms of Epigenetics40:52 Licking Rats Part 255:21 Outro
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5 months ago
56 minutes 52 seconds

The Interactome
Episode 36: Noninvasive Neuroengineering
The human brain is arguably the most complex organ in the body - and its hard to do experiments on it in a lab setting without invasive tools like electrodes and injections in the brain itself. But what if we had less invasive tools for understanding the brain in the lab? Join Sarah and Joe as they talk with Schuyler, an MD-PhD candidate, about the wild world of non-invasive neuroengineering... and Dungeons & Dragons! Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Szablowski Lab: https://www.szablowskilab.org/ Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:09 Meet Schuyler!5:25 What is an MSTP?7:00 What does everyone do for fun?14:00 Breaking down Noninvasive Neural Engineering30:34 When will these techniques be used in clinical trial?32:58 Acoustically Targeted Chemo Genetics51:25 Can this be applied to space medicine?1:01:48 Outro  
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6 months ago
1 hour 4 minutes 11 seconds

The Interactome
Episode 35: Space Robotics
When you think of health care, space probably doesn’t come to mind! But the emerging field of space robotics can provide groundbreaking insights to the world of medicine! This episode, Texas A&M robotics engineer Emily Wilkinson  sits down with Natalie and Sarah to discuss her career journey, current research, and her NASA internship (where she met Sarah!). Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.comTexas A&M RAD Lab: https://rad.engr.tamu.edu/ Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:49 Meet Emily!2:54 Getting to NASA11:48 The Internship15:09 How Emily and Sarah Met27:20 Emily's Current Job and How She Got There36:36 Projects That Emily's Lab Does47:19 A Day in the Life of Emily1:00:09 Radiation Testing1:08:53 Outro
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7 months ago
1 hour 14 minutes 31 seconds

The Interactome
Episode 34: Understanding Urban Planning
Whether it's the city, the suburbs, or somewhere else, have you ever stopped to think about why place where you live is designed the way that it is? That's thanks to urban planners, of which our guest this episode - Angela Lei - is! Join Angela, Sam, and Sarah as they discuss what urban planners and engineers do in terms of zoning, considerations made for pedestrians, and a little bit of history around Boston's Chinatown. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:20 Meet Angela!3:51 What is Urban Planning/Engineering?8:53 Exurbs14:37 Zoning21:51 Transit Oriented Development (TOD)30:47 Urban Planning's Impact on the Environment33:48 Boston's Chinatown40:46 Defining Borders and Splitting Land43:37 Pedestrianism and Climate Resiliency45:38 What Can You do to Impact Urban Planning in Your City47:00 The Inner Belt and the Highway That Never Was59:34 Redesigning a City Built for Cars1:13:20 Outro
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8 months ago
1 hour 14 minutes 58 seconds

The Interactome
Episode 33: Spectacular Space Medicine
What do doctors and astronauts have in common? Turns out, it’s more than you might think! On this episode, Sarah and Maia are joined by Shawna Pandya, MD. Shawna is a physician, astronaut and scientist. Tune in to hear her talk about navigating health care in the most extreme environments, and how she helps patients survive and thrive!   Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com   Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future   Timestamps:0:00 Intro0:47 Meet Shawna!2:39 How Shawna Became an Astronaut11:11 Space is Trying to Kill You18:05 Training for Space27:00 Other Cool Tech Related to Space Medicine29:54 Working on a Team of Highly Skilled Individuals34:29 Shawna's Upcoming Mission42:30 One Piece of Advice for Aspiring Astronauts45:30 Outro
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9 months ago
46 minutes 34 seconds

The Interactome
Episode 32: How to Parent Your AI
AI doesn’t typically make people think of parenting, but when you listen to this episode you’ll be shocked by the similarities! Cole Smith walks us through how to train AI, how it differs from machine learning, and why building an AI system can feel a lot like raising a child. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:15 Meet Cole!2:32 How Did Cole Get Into This Space?4:17 What Exactly is AI?8:42 Classifying AI11:40 The Difference Between AI and ML16:34 What is AI Good At?19:45 What is Generative AI?32:01 What is a Large Language Model?34:41 What Can't AI do?42:49 Bias in AI53:20 Choosing the Right Model59:54 Where Does Cole Think AI is Heading?1:05:38 Outro
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11 months ago
1 hour 6 minutes 48 seconds

The Interactome
Episode 31: Perceiving the Big Picture
Effectively communicating scientific concepts and discoveries is one of the hardest, and most important, ways of bridging gaps between scientists and the general public. But as all things in science, this is easier said than done.  On this episode, Joe, Sam and Natalie chat with New York Times science journalist and bestselling author Jim Robbins. He discusses his approach to writing about untold stories of the natural world, new research, and more. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:02 Meet Jim!4:45 Science Writing vs Science Research6:07 What Does Jim Write About?12:44 Jim's Start: Stories About Grizzly Bears15:51 California Wildfires21:22 Making Important Concepts Meaningful34:02 Navigating the Unknown in Storytelling and in Life49:56 Challenging the Status Quo54:13 What Makes a Good Story?57:04 Maintaining Optimism and Hope1:03:40 Outro
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1 year ago
1 hour 4 minutes 45 seconds

The Interactome
Episode 30: Diet on the Brain
On this episode of the Interactome, special guest Rasa Valiauga joins Natalie and Sarah to discuss the link that our diet has with our brains. Topics include what foods are considered highly glycemic and what that can mean for our bodies, how diabetes links to our diet, and discussing how to trim the fat from sensationalized diet advice and find the facts. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:44 Meet Rasa!7:26 Linking Diet to the Brain12:22 High Glycemic Food16:01 Type 1 and Type 2 Diabetes20:44 Rasa's Research31:12 How to Find the Facts in Sensationalized Headlines39:08 Rasa's Research Part 243:18 What Should be Brought to the Diet Conversation?45:40 Closing Thoughts
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1 year ago
49 minutes 13 seconds

The Interactome
Episode 29: Demystifying the Microbiome
You’ve probably heard of the microbiome, but there’s much more to it than just gut health. Tune in to hear from Bridget O’Connor, career microbiologist, for a discussion on the microbiome, how microbiologists study organisms they can’t see, and more! Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:40 Meet Bridget!10:07 Human Cell Biology vs Microbiology26:03 Microbiome Misconceptions35:53 Dysbiosis37:37 Importance of Strain Variety in Microbiomes50:36 Some Things That Bridget Wishes More People Knew About Microbiology54:35 Outro
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1 year ago
55 minutes 25 seconds

The Interactome
Episode 28: Bird Biology Bonanza
This week, the Interactome team is joined by Dr. Alex Champagne, Associate Professor of Biology at  University of Southern Indiana! The team talks all things bird physiology — the age old question of flight evolution, interesting anatomical structures, and Dr. Champagne’s current work (which just got published, by the way)! After listening to the episode, read about how skin lipids in desert bats suggest wing and tail membranes are important to evaporation cooling! https://www.sciencedirect.com/science/article/abs/pii/S1095643324000473 Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/ Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:26 Meet Alex!7:47 Discussing Bird Physiology and its Relationship with Evolution19:54 Adaptation and Evolution25:10 Alex's Work42:23 Archaeopteryx and Microraptor52:44 Rapid Fire Bird Questions1:04:31 Outro1:06:10 BONUS Everyone's Favorite Birds
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1 year ago
1 hour 9 minutes 33 seconds

The Interactome
Episode 27: Neural Networks
You've probably heard of AI powered neural networks, but are you familiar with biological neural networks? Join Sam, Natalie, and returning guest Youngmin as they compare, contrast, and generally discuss both types of networks. Can a single neuron "think"? And how do neural networks "learn"? We cover these questions and more on this episode of the interactome. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.comYoungmin's channel: https://www.youtube.com/c/ADHDMathematician Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:25 Meet Youngmin (again!)2:50 What is a Biological Neural Network?7:15 Can One Neuron Think?10:01 Suppressed Ommatidium16:30 Is the Adaptation to White Noise A Result of a Neural Network?26:23 Modeling Neurons29:33 How Does a Neural Network "Learn"?40:27 Comparing Biological and Artificial Neural Networks1:00:52 Outro
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1 year ago
1 hour 2 minutes 28 seconds

The Interactome
Episode 26: Wheying In on Proteins
We all know that protein is something in our food, but what else do proteins do? For our final episode of our 3-part series on the Central Dogma, we discuss (one of) the final products of DNA and RNA: proteins! We cover everything from where proteins come from to some of their roles as molecular machines. Along the way, we touch on topics such as how eating protein helps you make muscles to "the protein fold that kills." Correction: X-ray crystallography shoots high-energy photons (x-rays), not electrons, at crystals to obtain their structure. Sam was probably too excited thinking about electron microscopy to catch his mistake.Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:44 What are Proteins?14:41 How are Proteins Made?22:42 Protein Folding30:05 Side Topic on Microscopes38:19 Protein Regulation41:49 Protein DB44:36 When Protein Folding Goes Wrong54:03 Favorite Proteins1:0024 Outro
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1 year ago
1 hour 3 minutes 15 seconds

The Interactome
Episode 25: It’s RNA’s World, And We’re Just Living In It
Welcome to our part 2 of the central dogma of biology series! In this episode, Maia, Joe and Natalie talk all things RNA. Tune in to learn about the molecular structure differences between RNA and DNA, mRNA vaccines, and to hear some polarizing biological theories! Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro5:00 What is RNA?17:02 RNA Structure19:53 The RNA World Hypothesis26:11 Catalysis28:40 The RNA World Hypothesis Part 236:08 Maia's Research on RNA42:17 Joe's RNA Story49:19 RNA Current Events1:00:34 Outro
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1 year ago
1 hour 1 minute 35 seconds

The Interactome
Episode 24: Phishing and Smishing
What’s spookier than identity theft, scams and fraud? In the digital age, cybersecurity is more important than ever. Yet, there are many misconceptions about the field and what it entails. October is cybersecurity month, and to celebrate Sam, Joe and Natalie spoke with SecOp analyst Virginia Gresham. The crew talked about about her role, the importance of protecting your information, and more. Give it a listen, guarantee you’ll learn something new!  Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro1:15 Meet Virginia!6:40 Defining cyber security12:11 Day-to-day incidents15:00 Phishing19:00 Incident reports and security policies24:34 What to do during an incident30:08 What can happen if you are a victim of a cyber attack?32:20 Discussion of online privacy41:00 Ransomware44:38 Best practices for staying safe online51:39 Outro
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2 years ago
53 minutes 5 seconds

The Interactome
Episode 23: Investigative Mindset
Content Warning: this episode discusses dead bodies, violent crime, and international conflictOn this show, we talk a lot about modeling the scientific mindset, but scientists aren’t the only professionals asking tough questions. This week, we’re joined by a retired FBI agent who tells us all about how to ask the right questions and solve problems at hand. Oh, and there’s a surprise connection between our guest and a host, so make sure to tune in! Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.comScott's Channel: https://www.youtube.com/@ExFedHomestead Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro5:30 Keeping an Open Mind16:16 Persistence with a Purpose 25:00 Keeping Calm Under Pressure31:36 It's Ok to Not be an Expert in Everything42:33 Peer Review vs Judge's Review46:58 Peer Reviewer #249:33 Closing Thoughts54:06 Outro
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2 years ago
54 minutes 59 seconds

The Interactome
Episode 22: Lightning McDNA (Genetics)
In this episode, Joe, Maia, and Natalie talk about genetics. They start with the basics, and then delve into how we get our DNA and how it can change over many many years. You're bound to learn something new with this episode of the interactome! Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesTranscript: Margaret DownsIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:27 What is DNA?11:59 What is a genome?12:59 What is a gene?15:53 Introns and Exons19:18 Promoters and Terminator Sequences21:54 How you get your DNA23:51 Genomes Across Species: Plants29:05 Story time: Where did you first hear about DNA?30:45 Genomes Across Species 2: Bacteria34:00 Can genes change?37:50 How gene mutations play into evolution46:34 Outro
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2 years ago
47 minutes 32 seconds

The Interactome
Episode 21: Gateway to GIS
When we think of science, we often think of data being collected in test tubes and laboratories, but lots of data actually exists in the context of mountains, roads, neighborhoods and countries. Join Joe, Sarah and Natalie and special guest Rylee Wrenner as they discuss Geographic Information Science (GIS), which allows researchers to understand the kinds of data that are best visualized on a map. Along the way, they discuss how to make useful models, the centuries-old origins of GIS in epidemiology, and somehow manage to relate GIS to cheese. Join us to learn about GIS and witness our continuing inexplicable obsession with dairy products. And no, we are not sponsored by the cheese section at Trader Joe's. Seriously, Natalie, I shouldn't have to add this to an episode about GIS. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:38 Meet Rylee5:12 What is GIS?12:28 Applications of GIS13:45 Accessing and using GIS17:17 Rylee's work19:39 What disciplines are involved in GIS?22:43 What do you need to get started with GIS?25:03 Obtaining good data for GIS28:29 Data privacy34:57 The cheese party36:34 What makes a good model?38:52 Rylee's long-term GIS goals40:58 Final thoughts43:52 Outro
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2 years ago
44 minutes 54 seconds

The Interactome
Episode 20: Mighty Mitochondria
You might have heard the phrase "the mitochondria is the powerhouse of the cell" back in high school biology class, but what does that mean? Join Joe, Sam, and Maia as they explore everyone's favorite part of the cell. We had some fun with this, so join us as we explain what exactly the mitochondria is, how it works, and what happens if it breaks. Along the way, we'll talk about electron hot potato, grand theft organelle, at least one deadly poison, and, yes, find out that Joe has more than one brain cell. Links:Our Website: https://interactomemedia.wixsite.com/websiteTwitter: https://twitter.com/theinteractome Instagram: https://www.instagram.com/interactome_media/Mastodon: @interactome@universeodon.com Credits:Audio/Video Editing: Sam PickellArtwork: Maia ReyesIntro/Outro Music: Geovane Bruno - Dancing In The Future Timestamps:0:00 Intro2:40 What's in a cell, anyway?6:53 What does mitochondria do?23:19 How did mitochondria become a part of cells?33:08 Discussion of mitochondrial DNA45:24 Mitochondrial related diseases and therapies54:32 Going to space makes your mitochondria unhappy59:10 Outro
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2 years ago
58 minutes 48 seconds

The Interactome