What is autism? Is it truly on the rise, along with the broader concept of ‘neurodivergence’? With one in six children now identified as having special educational needs, could this increase be due to over-diagnosis, genetic factors, or something more? In this episode, I’m joined by three pioneers in the field—experts with extensive experience working with thousands of children diagnosed with autism. Together, we uncover the true scale of the issue and explore why our children's mental and physical health is under attack. Joining me are: Dr. Lorene Amet – Director of The Lauriston Centre in the UK, holding a PhD in Molecular Biology from the University of Oxford and a Master’s in Autism Education. She has conducted postdoctoral research at Princeton and Edinburgh universities. Beth Lambert – Founder of Documenting Hope, a non-profit dedicated to children's health. She’s a teacher and the author of A Compromised Generation: The Epidemic of Chronic Illness in America’s Children, as well as co-author of Brain Under Attack. Dr. Heather Tallman Ruhm – A board-certified physician with a Master’s degree in Public Health Policy. She has over a decade of experience as a college professor and serves as a medical advisor for Documenting Hope. Together, we dive deep into what’s beneath the surface - examining why our children's well-being is increasingly under threat. Further Information Read more in my book Upgrade Your Brain and on my website www.patrickholford.com Book for charity Food for the Brain's online practitioner conference 'Our Children's Brains are in Crisis' on Thursday 24 April, 9.00am - 5.45pm (for health practitioners).  Book webinar Optimising Neurodivergence, Thursday 24 April, 6.30pm (open to all).    

To what extent is a child’s mental health set in pregnancy? What can women do in pregnancy to ensure optimal mental health for their child? Also, what happens to women’s brains and mental health when their nutrition is sub-optimal in pregnancy? How can we help children and teenagers to achieve their full potential for mental health? In this podcast, I'm speaking to Julia Rucklidge, Professor of Clinical Psychology in the Department of Psychology and the Director of the Mental Health and Nutrition Research Group at the University of Canterbury in New Zealand. Learn more on my website - nutrition for Children's Health and Pregnancy as well as my books Optimum Nutrition for your Child and Optimum Nutrition Before, During and After Pregnancy.

To what extent is your health destiny pre-determined? Is it nature or nurture – what you eat and how you live that determines your health history? My guest in this podcast is a specialist in nutrigenomics. That is the field of rich interactions between your genes and your environment. Emma Beswick is not only a nutrigenomic expert but also a graduate from the Institute for Optimum Nutrition so she knows her stuff about nutrition too and is very much hands on, running one of the best gene testing companies in this field: LifecodeGX. In this podcast she demystifies genes and explains how they work, how we can identify our genetic uniqueness and the direct knock on effect that has on your personal optimum nutrition.  Go to my website for more information on nutrition. Sign up to my E-News on the home page of my website at www.patrickholford.com to receive news updates. Do follow my podcast channel to be informed of new podcast as they are released. Share with friends and family to help them achieve optimum health. 

Dr Christopher Palmer is a Harvard psychiatrist and researcher working at the interface of metabolism and mental health. He is an Assistant Professor of Psychiatry at Harvard Medical School and the Founder and Director of the Metabolic and Mental Health Program and Director of the Department of Postgraduate and Continuing Education, both at Harvard and at the McLean Hospital. He is author of the best-selling book, Brain Energy, in which he argues that mental disorders are metabolic disorders impacting the brain, and is leading the way to a paradigm shift in psychiatry towards new ways of understanding and treating mental health. Go to my website for more information on nutrition and mental health as well as the ketogenic diet. See also my book Upgrade Your Brain. Sign up to my E-News at www.patrickholford.com to receive news updates.

The latest iteration of the highly influential Lancet Commission on dementia prevention, authored by numerous professors from around the world, led by University College London’s psychiatry Professor Gill Livingston has, for the third time, ignored the hardest hitting evidence for homocysteine lowering B vitamins, misrepresented the science on omega-3 and concluded that the evidence for ‘unhealthy diet’ didn’t meet their high bar for inclusion as a modifiable risk factor. Several eminent professors are up in arms and have written to the Lancet. In this podcast I interview three of them – Professor Joshua Miller, Professor of Nutritional Science at Rutgers University; omega-3 expert Professor William Harris from the Fatty Acid Research Institute (FARI) and Professor Richard Johnson from Colorado University’s School of Medicine - to explore how the establishment continue to side-line nutrition. Read more on Alzheimer's, Dementia and brain health on my website.  Read the Lancet report.  More about Food for the Brain.

I’m talking to Steve Bennett, author of The Fibre First Diet, a book which proposes that simply re-ordering the foods you eat can trim your waistline and prevent diseases. We get under the hood of what’s really going on and how to gain control of your weight and health without feeling deprived. We will explore insulin resistance and how to reverse it, what really drives hunger, quick solutions to cut your cravings and why not all fibres are created equal. Also, the Japanese fibre that doctors prescribe to help reverse diabetes. Find out about his book The Fibre First Diet.  Find out more on weight-loss and blood sugar balance on my website.

Keeping your brain young is a science. Ageing happens because of oxidation (think wrinkly skin). Nowhere is there more oxidation activity than the brain because your brain uses more energy than any other organ and generates more oxidants. There are 7 key antioxidants which, together recycle each other. These are vitamin C, E, glutathione, anthocyanins, co-enzymeQ10 and alpha lipoic acid. There’s a second line of defence involving B vitamins and minerals such as selenium and zinc. In this podcast I’ll be talking with the antioxidant expert Associate Professor David Vauzour, Dr Filip Van Hulle, a leading expert in CoQ10 and brilliant analytical chemist Dr Konrad Kowalski who has developed a simple test to find out how your brain is ageing and what to do about it. What anti-ages your brain also anti-ages your body. Listen to this podcast to add years to your life and life to your years. Find out more about how to Upgrade Your Brain.

In this podcast, I bring the three top scientists who know more about fats and the brain than any others - Professor Michael Crawford, visiting Professor at Imperial College London and head of the Institute of Brain Chemistry and Human Nutrition, Professor William Harris from the Fatty Acid Research Institute (FARI) and neuroscientist Dr Simon Dyall, a director of of the International Society for the Study of Fatty Acids and Lipids -  to get inside our brains. I’m most interested in the point of disagreement, the contradictions, the evidence that doesn’t fit the model. So often, by stirring things up we learn something new. Is it all about omega DHA? So why is evidence for EPA sometimes working even better for mental health? What about phospholipids? Is it all about choline, which is just one of five phospholipids. Where does vitamin D, a fat based hormone fit in? These are some of the topics we explore. Find out more about the Upgrade Your Brain campaign on my website.

My guest today is Dan Kittredge, who knows more about what makes food nutritious than anyone I know.  Dan Kittredge has been an organic farmer for more than 30 years and is the founder and executive director of the Bionutrient Food Association (BFA), a non-profit whose mission is to “increase quality in the food supply.”  Known as one of the leading proponents of “nutrient density,” Dan works to demonstrate the connections between soil health, plant health, and human health. Out of these efforts was born the Bionutrient Institute, which has engineered a prototype of a hand-held consumer spectrometer, designed to test nutrient density at point of picking or purchase.  He has decades of experience literally testing growing methods and measuring the nutrient density both in plants and livestock. As people extol the benefits of organic, zero-dig, regenerative farming and the harms of our herbicide and pesticides laden food supply, Dan has actually been measuring and working out what farmers and growers have to do to get the healthiest soil for the healthiest plants. Not only am I honoured to have Dan as my podcast guest but also he’s coming to our farm in the Black Mountains in June to teach us, and others, how to grow super-nutritious food. See foodforthebrain.org/kittredge-workshop

Ask the man in the street what’s driving Alzheimer’s and they’ll probably say a third is in the genes. Or that it’s just what happens when you age. Neither of these statements are true. Alzheimer’s is a largely preventable disease and my guests today are tackling the two fundamental questions. Firstly, what are the positive and negative behaviours – diet, lifestyle, environment – that prevent and drive dementia? And secondly, how do you change those behaviours. In today’s podcast I talk with Assistant Professor Tommy Wood, from the University of Washington about the what, then Dr Kristina Curtis, a behavioural scientist and honorary lecturer at the University College London who heads the Applied Behaviour Change team, about the how of behaviour change. Go to my website for more information on nutrition and mental health See also my book Optimum Nutrition for the Mind. In April I'll be publishing my new book Upgrade Your Brain - sign up to my E-News at www.patrickholford.com to receive news updates and book availability. 

My podcast guest is Dr Georgia Ede, MD, a Harvard-trained, board-certified psychiatrist based in Northampton, Massachusetts, USA. Her interest in nutrition arose after discovering a new way of low carb ketogenic eating that reversed several bewildering health problems. Her speciality is nutritional and metabolic psychiatry and ketogenic diets. Her passion is empowering people with psychiatric conditions to reduce or eliminate the need for medications by changing how they eat. But which changes are worth making, and why? That’s both the subject of her new book Change Your Diet Change Your Mind, just out, and this podcast. Go to my website for more information on ketogenic dieting in the Go Hybrid section and for nutrition and mental health See also my book Optimum Nutrition for the Mind. In April I'll be publishing my new book Upgrade Your Brain - sign up to my E-News at www.patrickholford.com to receive news updates and book availability. 

My guest today is Uma Naiidoo who founded and directed the first and only hospital-based program in Nutritional, Lifestyle and Metabolic Psychiatry and is Director of Nutritional and Psychiatry Service at Massachusetts General Hospital and serves on the faculty of Harvard Medical school. Her books Your Brain on Food and The Food Mood Connection are bestsellers in the US. Here we focus on anxiety and her new book How to Calm Your Mind with Food - out yesterday. For more on nutrition and anxiety see the Anxiety topic on my website. Also see my book The Stress Cure.    

My podcast guest today is a legend in the world of omega-3. Dr Bill Harris is Professor in the Department of Medicine in the Sanford School of Medicine at the University of South Dakota. He has been a front runner in measuring omega-3 status and developed the omega-3 index, running studies on the effects of omega-3, with more than 300 published pieces of research to date, backed by five National Institutes of Health grants. Perhaps best known for his expertise in relation to omega-3 and heart health. He obtained his PhD doctorate in Human Nutrition from the University of Minnesota and did post-doctoral fellowships in Clinical Nutrition and Lipid Metabolism with Dr Bill Connor at the Oregon Health Sciences University back in the 1980’s. He has had his finger on the pulse of omega-3 research ever since. In this podcast, we are discussing his latest study on omega-3 status as a predictor of Alzheimer’s and  dementia risk.  Read more about Alzheimer's and Dementia on my website. Also see my book Upgrade Your Brain.

Homo sapiens brain size is 20% less than it was 29,000 years ago. IQ is also falling 7% a generation. Mental illness is on the increase. Why?   Why are our brains shrinking?   Today’s guest is Professor Michael Crawford. He discovered that brains are made out of omega-3 DHA in the 1970s. He is the Director of the Institute of Brain Chemistry and Human Nutrition.   At Chelsea & Westminster he has shown that pregnant women lacking omega-3 make a ‘filler fat’ called oleic acid, blood levels of which predict brain developmental and cognitive problems in their babies. His new book The Shrinking Brain explains why humanity is devolving, with dire consequences, unless we take action now to put nutrition and brain health at the top of the agenda.   Find out more about brain health on my website.     

For a change, in this month’s podcast I’m interviewed by Philly J Lay,  a long-standing advocate for our health and that of our planet. She is passionate in her belief that everything is connected and that when we learn to heal ourselves, we will start to heal this beautiful planet. After a near death experience and years of grief, resulting in a range of chronic illnesses, she discovered personalised natural medicine and the associated miracles of the body and power of the mind, which she wrote about in her first book, The Natural Wellness Journal. In this podcast she interviews me about my health journey and why I’m passionate about the power of optimum nutrition on mental health. We'll be covering: Understanding Alzheimer's Disease: Explore the basics of Alzheimer's disease, including its symptoms and prevalence. The Impact of Nutrition: Discover how nutrition plays a pivotal role in brain health and the prevention of Alzheimer's. Brain-Boosting Foods: Insights into specific foods and nutrients that can support cognitive function and reduce the risk of Alzheimer's. Nutrition and Lifestyle: Learn about the holistic approach to Alzheimer's prevention, including the role of lifestyle factors such as exercise and stress management. The Importance of Early Intervention: Understand the significance of early dietary interventions in promoting brain health throughout life. Visit my website to learn more about optimum nutrition and mental health. Or see my books The Optimum Nutrition Bible, Optimum Nutrition for the Mind and The Alzheimer's Prevention Plan.

We are told serotonin deficiency causes depression; too much cholesterol excess causes heart disease; too much acid causes heartburn. Now we are being told too much amyloid causes Alzheimer’s.  These statements are the key rationale for selling antidepressants, cholesterol lowering drugs, antacids and soon, anti-amyloid antibody injections. But are they true or are they myth stories designed to sell drugs, cloaked in dubious circumstantial evidence, backed up by medical guidelines, but not by the actual science or what actually causes these diseases? Join me in conversation with award-winning medical journalist, Jerome Burne.  Read more in my blogs and reports on my website.

Why does your brain fuel on either glucose or ketones, derived from fat? Why do the brains of babies need ketones for rapid building on their neural network? Can eating fats, such as C8, help prevent or reverse brain ageing? Do you have to go ketogenic to get the benefit? How can a ketogenic diet or supplements help mental health and mental illness? To answer these and other questions and explore the whole role ketones and fat play in your brain health, my podcast guest this month is the leading world expert, Professor Stephen Cunnane, who heads the Brain Research Team at Sherbrooke University in Sherbrooke, Quebec, Canada. Professor Stephen Cunnane holds the clinical research chair in ketotherapeutics. His research is focused on how ketogenic interventions (supplements, diets) can help prevent Alzheimer’s, slow down cognitive decline and deliver more ‘brain power’. We will also be talking about the latest research showing how ketogenic diets can help Parkinson’s, epilepsy and other mental and neurological conditions including their effects on mood and anxiety. Find out more about Ketogenic dieting and mind health on my website.      

The number of children diagnosed with autistic spectrum disorders has escalated from 1 in 250 to 1 in 58 last year in the US. Although often described as ‘genetic’ obviously the genes haven’t changed, so what’s going on in the environment that’s driving this rapid breakdown in neurodevelopment? Paul Shattock OBE has spent his life researching autism, and is the Chair of the ESPA (Education and Services for People with Autism) and former director of the Autism Research Unit at the University of Sunderland. There he showed that many autistic children had ‘casomorphins’ and ‘gliadorphins’ – opioids created from wheat and milk when the gut is leaky – in their urine. This is but one of many factors linked to increasing risk for ASD and other neurodevelopmental problems. We’ll be having a frank discussion about everything from vitamins to vaccines, essential fats to environmental toxins - learning from a man whose dedicated decades to finding out what’s going on and how to help children and their families. For more information about nutrition and brain health go to the mind health topic on my website or see Optimum Nutrition for the Mind.

Professor Thomas Seyfried is renowned in the field of cancer for helping keep people with aggressive cancers stay alive by following his science-based protocols. How? That’s what we will find out. Thomas Seyfried is Professor of Biology at Boston College and received his PhD in Genetics and Biochemistry from the University of Illinois back in 1976 when genetics was in its infancy. He was Assistant Professor in the Department of Neurology at Yale University School of Medicine. He has received Lifetime Achievement Awards from the Academy of Complimentary and Integrative Medicine among others and the Uncompromising Science Award from the American College of Nutrition for his work on cancer. Tom has over 200 peer-reviewed publications to his name and is author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer. You can read more about cancer and my ketogenic/low carb Hybrid diet on my website. 

In this podcast I interview two pioneers in making food healthy, from the soil up. Bob Quinn is a botanist with a PhD in plant biochemistry, who helped convert thousands of acres across Montana to growing ancient grains (Kamut) organically. He was the first in Montana to mill whole grain, organic flour starting in 1986.  By 1991 he had certified his entire 3 generation family wheat and cattle ranch as organic.  He continues to experiment to improve regenerative organic systems and find better ways to grow dry land vegetables, fruit trees and berries in Montana, not only rebuilding the soil, but also the farming community for the benefit of health for all. Tim Parton is a Farm Manager in South Staffordshire in the UK. Tim farms in a biological way maximizing the value of nutrition to get the best out of the crops. He does not use insecticides, seed treatments, growth regulators or fungicides, as when the plant is balanced the need for synthetic inputs drops away. Tim has won many awards including Soil Farmer of the Year 2017, Arable Innovator of the Year 2019, Sustainable Farmer of the Year 2019 and Innovation Farmer of the Year 2020. Together, we’ll explore the journey between the soil and your health and why soil degeneration, and modern farming practices are partly responsible for declining mental and physical health. We will also explore the fundamental principles of regenerative farming and gardening. See more information on my website and nutrition and the environment. Find more about my rap Fight the Flour.