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In this episode, Mikki speaks with Professor Michael Snyder, Chair of Genetics at Stanford University and a global leader in personalised medicine. They explore how our genes, gut microbiome, and lifestyle choices interact to shape metabolic health—and why we all respond so differently to the same foods. Mike shares insights from his groundbreaking research using wearables and genomics to track health in real time, the future of personalised nutrition, and how continuous glucose monitors (CGMs) can help anyone understand their body better. They also discuss the link between viral infections and diabetes, why strength training matters more than you think, and how food truly functions as medicine.
Highlights:
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A lot of “natural” stress aids aren’t harmless—because they actually work. In this Mini Mikipedia, Mikki breaks down how popular adaptogens and nutrients interact with your HPA axis (the body’s stress-response command centre) and when that’s a blessing versus a blind spot. You’ll learn what the evidence says for ashwagandha, rhodiola, holy basil, phosphatidylserine, and why liquorice root is uniquely risky. Mikki covers dose ranges used in studies, who should be cautious (thyroid issues, pregnancy/breastfeeding, low cortisol, meds), how to test cortisol properly, and why cycling supplements beats “more is better.” She also revisits the basics that move the needle—sleep, protein-centred meals, training balance, boundaries, and connection—so supplements can supplement a solid plan, not replace it.
Highlights
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This week on the podcast, Mikki speaks to Hollie Nicholson — trainer, nutrition coach, and creator of the STRONG Method™, a program that’s helped thousands of women over 40 reclaim their confidence, strength, and energy.
In this conversation, they talk about what it really means to train and thrive as a busy woman in midlife. Hollie shares how she found her passion for helping women over 40, the biggest training mistakes she sees, and how her own approach has evolved — from “lifting like cardio” in her twenties to prioritising muscle and recovery now. They dive into mindset shifts, hormonal changes, and the reality of balancing fitness with family and work. Hollie also opens up about how to navigate body changes with compassion, stay consistent when life feels chaotic, and why self-care isn’t selfish — it’s strategic.
Hollie is a French fry–loving, dessert-ordering, early-to-bed Midwest mum of three who feels most alive in the mountains and always has an afternoon Diet Coke in hand. In 2020, she swapped her fifth-grade classroom for a Zoom screen and discovered a dream she didn’t know she had. What began with 40 women in a garage grew into a global movement — and today, Hollie helps women everywhere get stronger, inside and out.
Hollie and her programs can be found here https://www.hollienicholsonstrong.com/about-me
https://www.instagram.com/hollienicholsonstrong/?hl=en
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Calorie cycling isn’t a trick—it’s stress management for your metabolism. In this Mini Micropedia, Mikki explains how sustained restriction can drive adaptive thermogenesis: leptin falls, ghrelin rises, thyroid output dips, NEAT declines, and fat loss stalls. Then she lays out practical cycling options—from simple weekday–weekend shifts to planned carb refeeds, diet breaks, and PSMF days—so you can periodise your intake around training and real life without blowing your deficit. You’ll learn who benefits (and who shouldn’t use it), why protein (≥1.6–2.2 g/kg) and resistance training are non-negotiables, and how to set your weekly calorie budget, distribute it across the week, and interpret scale bumps from glycogen and water. The goal: precision over punishment—an approach you can actually sustain.
Don’t miss Mikki’s webinar “Fat Loss in the Festive Season” on Wednesday 29 October, running at 1:00 pm and 7:00 pm NZT.
Episode Highlights
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This week on the podcast Mikki speaks to Dr CAtherine Crofts in part 2 of their discussion on health about challenging the status quo in nutrition science. Together they take a critical look at the flaws in current dietary guidelines, particularly the persistence of high-carbohydrate, low-fat recommendations despite mounting evidence for alternative approaches.
The conversation dives into how our bodies handle minimally processed versus highly processed carbohydrates, the individuality of carbohydrate tolerance, and why excessive processed carbs play such a central role in driving insulin resistance and chronic disease.
Drawing on evolutionary and anthropological insights, the discussion considers what our history of hunting, brain expansion, and plant consumption suggests about human adaptation to diet. This leads into the striking health shifts seen in indigenous populations exposed to modern foods, and whether refined carbs and oils are the primary culprits or part of a wider cultural disruption.
Dr Catherine Crofts is a pharmacist, researcher, and lecturer based in New Zealand with a special interest in the early detection and prevention of metabolic disease. She completed her PhD at Auckland University of Technology, where she analysed the extensive insulin assay data collected by Dr Joseph Kraft, shedding light on how abnormal insulin responses can precede changes in blood glucose by many years.
Catherine’s work focuses on hyperinsulinemia as a key driver of chronic disease, highlighting the limitations of relying solely on glucose-based measures such as HbA1c or fasting glucose. She has presented internationally on the clinical importance of Kraft’s insulin patterns, advocating for earlier and more nuanced testing to improve long-term health outcomes.
With a background that combines pharmacy practice, clinical research, and teaching, Catherine brings a rare blend of practical experience and scientific insight to the conversation around metabolic health and diabetes prevention.
linkedin.com/in/catherine-crofts-4a25537b?originalSubdomain=nz
https://academics.aut.ac.nz/catherine.crofts
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This week on Mini Mikkipedia, Mikki takes a deep dive into the science of Urolithin A — the “mitochondrial molecule” making waves across the health and longevity world. Is it a genuine breakthrough or just another overhyped supplement? Mikki unpacks the research behind this postbiotic compound, how it supports mitophagy (the clean-up and renewal of mitochondria), and what human studies really show about its impact on strength, endurance, and inflammation. She explores its potential for midlife health, particularly during perimenopause, and weighs it against the proven benefits of exercise, fasting, and a nutrient-dense diet. Expect an evidence-based take on whether it’s worth adding to your stack — or just good marketing dressed in lab coat chic.
Highlights:
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This week on the podcast Mikki speaks to returning guest Dr Mike T Nelson about physiological flexibility and the four physiological intervention points. An OG in the exercise physiology and nutrition space, Mikki and Mike talk about expanding metabolic flexibility, and fuel substrate use, to being flexible and resilient across other domains. They talk about temperature regulation, our pH buffer and lactic acid tolerance, and breath work to enhance our ability to deal with stress.
Dr. Mike T Nelson is a research-fueled Fitness and Nutrition educator. Dr. Mike T. Nelson has spent 18 years of his life learning how the human body works, specifically focusing on how to properly condition it to burn fat and become stronger, more flexible, and healthier.
He’s been called in to share his techniques with top government agencies, universities and colleges, fitness organizations and fanatics. The techniques he’s developed, and the results Mike gets for his clients have been featured in international magazines, in scientific publications, and on websites across the globe. His podcast Flex Diet Podcast is a wealth of information on all of these topics and more.
Mike can be found at: https://miketnelson.com/
Flex Diet Podcast https://open.spotify.com/show/42TdIuiFnDYHNWK9deio5l
Physiologic Flexibility Course Waitlist: https://miketnelsons.samcart.com/products/physflex/
Previous interview: https://podcast.mikkiwilliden.com/204
Mondays Matter Accelerated: https://www.mikkiwilliden.com/mondays-matter-accelerated
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GLP-1 drugs like Ozempic, Wegovy, and Mounjaro have become a cultural phenomenon, transforming appetite regulation and weight loss like nothing before. But with their rise comes a flood of imitators, from flashy “GLP-1 patches” to supplements like Calocurb, all promising the same results without the needles or prescriptions. In this episode, I break down what GLP-1 actually is, how these drugs work, and why they’re so effective—not just for weight but also for cardiovascular outcomes. Then I take a closer look at the patches (spoiler: marketing magic, not science) and Calocurb’s hops extract, which shows some early promise but lacks long-term data. If you’re curious about food noise, appetite regulation, and how to separate science from sales tactics, this one’s for you.
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Fresh off the finish line, Mikki recaps the Grand to Grand Ultra: a 7-day, 6-stage, 275 km journey across Utah–Arizona’s heat, altitude and endless sand. She breaks down the training block (back-to-back days, >100 km weeks, strength, sauna), the gear that mattered (hooded SPF top, RaidLight gaiters, 12 L pack), and a simple, robust fueling plan that worked: ~30–40 g carbs/hour with steady sodium (500–600 mg/h), plus ketones and blackcurrant extract for focus and gut calm. Expect honest lessons from a long day of 87 km—including 1 a.m. dunes—why supported made sense, how “jeffing” saved the legs, and the small camp rituals that sped recovery. It’s a practical, hype-free debrief for anyone eyeing multi-day desert ultras—or just curious how to keep moving when the terrain (and life) gets sandy.
Highlights:
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This week on the podcast Mikki speaks to Claire Turnbull, registered nutritionist about her latest book, End your fight with food. Claire has been a leading voice in health and nutrition for nearly two decades, helping thousands of people rethink their relationship with food, movement, and self-care. In her latest book, she brings together the science of behaviour change with the lived reality of growing up in a culture steeped in dieting, food rules, and body image pressures. What makes her work so powerful is not just her professional expertise, but her willingness to share her own story with honesty and vulnerability — from childhood experiences to struggles with disordered eating, motherhood, and mental health.
In this conversation, we dive into those personal reflections and the practical strategies she’s distilled for readers. We talk about how our early environment shapes food beliefs, the role of habits and the food environment, and why lasting change often comes down to self-belief as much as knowledge.
Claire Turnbull is a registered nutritionist, published author, and holistic wellness expert who founded New Zealand-based Mission Nutrition and findWellness. With a BSc in Dietetics, a diploma in Positive Psychology, and over 20 years of experience, she provides expertise in nutrition, mental health, and healthy lifestyle habits for individuals and businesses. Turnbull is also a regular media contributor, a keynote speaker, and has authored three books, including her latest, End Your Fight with Food, which explores her personal journey and acts as a workbook to help others connect in to what really matters to help heal their relationship with food and themselves
https://www.instagram.com/claire.turnbull/
https://missionnutrition.co.nz/
https://www.claireturnbull.co.nz/
https://www.claireturnbull.co.nz/shop-products/end-your-fight-with-food
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This week on the podcast Mikki chats to Paul Booth, sports nutritionist and exercise physiologist who helped lead Ruth Croft and Tom Evans to victory at the UTMB race in 2025, just gone. Mikki and Paul chat about his background, his thoughts on the 120g of carbs that some athletes are pushing (and subsequently his PhD research is studying) and the specific strategies used by both Tom Evans and Ruth Croft in the 100 mile iconic race. They also discuss other nutritional strategies, how these may relate to age group and midlife athletes.
Paul Booth is a sports nutritionist and exercise physiologist with a specialist focus on ultra-endurance performance. With over 20 years of experience in academia and applied practice, Paul has worked extensively with elite and amateur endurance athletes to optimise fueling, recovery, and race strategies.
He is the Lead Nutritionist for the Salomon International Team and consults with athletes across trail, ultra-running, and endurance sports. His research and practice centre on translating laboratory findings into practical approaches that account for the individual demands of athletes in real-world competition.
As a PhD researcher, Paul’s academic work investigates metabolism and nutrition in ultra-running. He has completed more than 80 ultramarathons and over 150 endurance events across disciplines including trail running, cycling, Ironman, and ski mountaineering. His combination of scientific expertise and personal experience allows him to provide grounded, evidence-based strategies tailored to the unique challenges of endurance sport.
https://www.instagram.com/ultra.endurance.nutritionist/
https://performancegainsnutrition.com/
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This Mini Mikkipedia digs into what truly keeps weight off long-term: self-regulation, flexible restraint, and a rock-solid routine. Mikki shares research-backed insights (inspired by prep for an interview with Brandon DaCruz) showing why maintenance gets easier after 2–5 years as habits hard-wire, and why frequent self-monitoring, meal planning, and clear relapse protocols matter more than “perfect” weeks. We unpack how exercise protects appetite regulation better than diet-only deficits, why consistency across weekends beats weekday austerity, and how identity shift and intrinsic motivation drive staying power. You’ll hear practical ways to course-correct after lapses, limit decision fatigue, and build supportive environments that withstand holidays, stress, and hyper-palatable food cues. Expect zero gimmicks—just evidence-based strategies to help you feel in control and sustain results without white-knuckle dieting.
Highlights
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This week on the podcast Mikki speaks to Prof Arny Ferrando about his work in protein, essential amino acids, protein timing, aging, anabolic resistance, and how to optimise muscle retention and fat loss.
Arny Ferrando is a Professor of Geriatrics at the University of Arkansas for Medical Sciences (UAMS), where he co-directs the Center for Translational Research in Aging & Longevity (CTRAL) and holds the position of Wes Smith Distinguished Chair in Geriatrics for Longevity, Health Promotion and Frailty Prevention.
His research deploys stable isotope techniques to dissect muscle protein metabolism under stress—from spaceflight, burn injury, joint arthroplasty, renal and heart failure, to aging and surgical recovery. He pioneers nutritional, pharmacological, and exercise-based strategies to counteract muscle wasting and functional decline.
After earning a Ph.D. in Nutrition & Physiology from Florida State University, he conducted postdoctoral work at NASA’s Johnson Space Center. He served as a U.S. Army pilot and armor officer, retiring as Lieutenant Colonel. He’s driven by a lifelong athletic spirit: from West Point gymnast to powerlifter, bodybuilder, masters track athlete, and now Krav Maga instructor.
He drives multiple research programs funded by NIH, the U.S. Army, and industry, and since 2023 holds a Visiting Senior Research Scientist appointment at IHMC, extending his work to human performance in extreme environments.
https://www.ihmc.us/groups/arny-ferrando/
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Mikki takes a deep dive into BMI, obesity, and a major shift in how obesity is being redefined in the scientific and medical community. Drawing on a recent Lancet Diabetes & Endocrinology Commission report and new cohort data from the All of Us research program, she unpacks why BMI alone is an inadequate measure, how new definitions of preclinical and clinical obesity provide more nuance, and what this means for individuals, clinicians, and policymakers. This conversation highlights the importance of looking beyond the scale to understand true metabolic risk and the wider societal costs of obesity. Listeners will come away with a clearer understanding of why obesity is being reframed as a chronic systemic condition—and why it matters for health outcomes and resource allocation.
Highlights:
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This week on the podcast Mikki speaks to naturopath Erin O’Hara about a resilient immune system. Erin chats about her early years as a professional athlete before switching gears and diving into natural health and naturopathy. Mikki and Erin chat about signs of a robust versus struggling immune system, whether there is such a thing as ‘boosting’ your immune system and what foundational lifestyle and supplements exist to support immunity.
Erin O’Hara combines her knowledge of Naturopathy and Science to provide an integrative and evidence-based approach to wellbeing. She has been involved in the Health and Wellbeing Industry for about 20 years through extensive University study (BSc and BNatMed), scientific research, and an intrinsic passion for health & wellbeing.
Her functional medicine approach addresses the underlying causes of disease through extensive testing and looking at the interactions among genetic, environmental, and lifestyle factors that can influence your health and cause disease. She utilises the best Evidence-Based Complementary Therapies to work in conjunction with conventional treatments. Drawing from her clinical experience and knowledge she takes quality time with each patient to understand the root cause of the disease, analysing test results, and provides an integrative approach to wellbeing.
Erin works with general naturopathy patients and is very experienced in complex hormonal issues, integrative oncology support, autoimmune conditions, digestive disorders, and mental health. There is no "one size fits all" wellness plan so her consultations are tailored to your individual and unique needs. Erin sees a wide range of patients, from children to elderly, who are seeking to improve their health, heal naturally, or support for an underlying health condition.
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In this Mini Mikkipedia episode, Mikki dives into new research from Dr. Fuchs and Professor Luc van Loon on the critical role of protein and activity in preserving muscle during hospitalization. She explains just how quickly muscle mass can decline with bed rest or critical illness, why standard hospital meals fall short nutritionally, and how inadequate protein and energy intake accelerate muscle loss. Mikki outlines practical strategies—from protein targets and essential amino acids to simple activity or electrical stimulation—to help mitigate muscle wasting. She also highlights the importance of “prehabilitation” before elective surgery. Whether you’re an athlete, a caregiver, or someone preparing for surgery, this episode offers valuable insights on protecting strength when it matters most.
✨ Episode Highlights:
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Mikki catches up with returning guest Marty Kendall to dive into his latest research on data-driven fasting—now evolving into “glucose-guided eating.” Marty explains how using a simple glucometer can help people calibrate hunger, avoid overeating, and make smarter food choices without rigid calorie counting. They discuss what makes this approach effective, who benefits most, and why personal thresholds matter more than one-size-fits-all advice. The conversation also explores nuances around satiety, macronutrient balance, micronutrient density, and even the broader systems—like food costs and guidelines—that shape our eating. If you’re curious about practical, personalised strategies for improving blood sugar, weight, and long-term health, this episode is packed with insights.
Marty Kendall is an engineer who seeks to optimise nutrition using a data-driven approach.
Marty’s interest in nutrition began eighteen years ago to help his wife Monica better control her Type 1 Diabetes.
Since then, he has developed a systematised approach to nutrition tailored for a wide range of goals, contexts and preferences.
Over the past five years, Marty shared his research at OptimisingNutrition.com.
He has developed Nutrient Optimiser and Data-Driven Fasting to guide thousands of people on their journey towards nutritional optimisation.
Marty can be found here: https://optimisingnutrition.com/
Prev appearance https://podcast.mikkiwilliden.com/120
https://podcast.mikkiwilliden.com/182
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In this Mini-Mikkipedia Monday episode, Mikki unpacks the often-confusing concepts of glycemic index, glycemic load, and glycemic response — and why knowing the difference matters. While glycemic index tables are widely used, they don’t always translate into real-world eating, since lab conditions rarely reflect how we actually consume food. Mikki shares insights from her own postgraduate lab days, explains why portion size and food combinations change the picture, and highlights how individual responses can vary dramatically. With research from studies like PREDICT and practical strategies for self-testing, she makes the case that personal glycemic response — not the number on a label — is the most important measure for your health, energy, and satiety.
Episode Highlights:
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