In this episode of Weight Loss Simplified, Jennifer Powter sits down with Marcelle Pick, OB/GYN, NP, to expose the hidden connection between stress, adrenal dysfunction, and weight gain.
If you’re exhausted, struggling to lose weight despite doing “everything right,” or constantly overwhelmed, your adrenals may be the missing link. Marcelle unpacks how chronic stress disrupts hormones, metabolism, and overall health—while Western medicine largely ignores the problem.
Discover why traditional weight loss advice fails women with adrenal dysfunction, how stress fuels weight gain, and the exact steps you can take to restore balance.
In this episode:
00:00 - Introduction: Why adrenal health is critical for women over 40
01:22 - Meet Marcelle Pick: Her 40+ years of clinical experience in women’s health
03:50 - What are the adrenal glands, and why do they matter?
05:21 - The stress response: How your body reacts to modern-day pressure
07:02 - The real impact of chronic stress on hormones, metabolism, and energy
08:50 - Why most women are misdiagnosed with thyroid issues instead of adrenal dysfunction
10:49 - Signs your adrenals are struggling: Fatigue, stubborn weight, brain fog, and more
12:26 - The link between perimenopause, menopause, and adrenal health
14:00 - Breaking the cycle: Practical strategies to restore adrenal function
16:33 - How diet, sleep, and lifestyle choices impact stress and cortisol
17:06 - The danger of fasting for women with adrenal dysfunction
19:42 - How unresolved trauma affects stress levels and weight loss resistance
22:32 - Why women need strong social support for long-term health
23:39 - Reconnecting with intuition: Why self-care isn’t selfish
25:30 - The wake-up call: How to listen to your body before it breaks down
27:11 - Why traditional medicine treats symptoms, not root causes
29:26 - First steps to take if you suspect adrenal dysfunction
30:18 - Free adrenal support guide: How to assess and start healing
Episode Resources:
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