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Trends from the Trenches

Bio-IT World

38 episodes

1 month ago

Rare diseases do not receive enough attention for the impact they have on patients and their families. This is what AlphaRose’s founder and CEO Casey McPherson learned after his daughter was diagnosed with a rare condition. In a conversation with host Ari Berman, McPherson shares how he switched from music to founding his own pharmaceutical company, what technologies AlphaRose is developing, and how his company is creating environments that allow innovation and iteration. He also shares his t...

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Rare diseases do not receive enough attention for the impact they have on patients and their families. This is what AlphaRose’s founder and CEO Casey McPherson learned after his daughter was diagnosed with a rare condition. In a conversation with host Ari Berman, McPherson shares how he switched from music to founding his own pharmaceutical company, what technologies AlphaRose is developing, and how his company is creating environments that allow innovation and iteration. He also shares his t...

Show more...

Episodes (20/38)

Trends from the Trenches

Episode: 37 - A Father’s Mission to Find a Cure: Casey McPherson on Rare Disease Research

Rare diseases do not receive enough attention for the impact they have on patients and their families. This is what AlphaRose’s founder and CEO Casey McPherson learned after his daughter was diagnosed with a rare condition. In a conversation with host Ari Berman, McPherson shares how he switched from music to founding his own pharmaceutical company, what technologies AlphaRose is developing, and how his company is creating environments that allow innovation and iteration. He also shares his t...

1 month ago

30 minutes

Trends from the Trenches

Episode: 36 - David Hewlett on Making Learning Fun and Data Standardization

David Hewlett, founder of Tech Bandits, makes learning fun and creates an environment where children—the future generation of scientists—can feel comfortable with curiosity. With host Ari Berman, Hewlett delves into his acting career, which consists of a wide range of scientist roles, and the origins of Tech Bandits. He also shares his thoughts on how science needs to be communicated better (and why scientists need to know how to present their work to the world), what technology can help with...

4 months ago

36 minutes

Trends from the Trenches

Episode: 35 - A Farewell to Stan Gloss: Founding BioTeam, Words of Wisdom, and More

In this special transition episode of Trends from the Trenches, Ari Berman, CEO of BioTeam, takes the mic as the new host of the Trends from the Trenches podcast and speaks with founding host Stan Gloss, co-founder of BioTeam. During their conversation, they cover Stan’s journey as an entrepreneur, including the valuable lessons learned along the way, words of wisdom for people on similar paths, and what he is most proud of during his time at the company. Stan also discusses the impact dyslex...

5 months ago

28 minutes

Trends from the Trenches

Episode: 34 - Discussing HPCs and Research Computing With Dirk Petersen

In the first Trends from the Trenches episode of 2025, host Stan Gloss and Dirk Petersen, Director of Supercomputing Center at Oregon State University, talk about the state and role of HPCs in a world that’s focused on AI. Petersen offers his thoughts and insights on working with AI teams, how to converge the traditional HPC user with the AI user, the “Wild West” of AI infrastructure and computing power, and how AI is driving a renaissance in scientific computing and high-performance computin...

8 months ago

29 minutes

Trends from the Trenches

Episode:33 - Renee Iacona Discusses AI/ML Expertise, Data Management, and Oncology

In this episode of Trends from the Trenches, host Stan Gloss and Renee Iacona, vice president of Oncology Biometrics, Oncology R&D at AstraZeneca, discuss the process of matching patients with the right treatments, data management (particularly around oncology), and the value of knowledge graphs. Iacona mentions the importance of having scientists who understand AI/ML and AI/ML experts who understand science. She also shares what AstraZeneca is doing with AI, how oncology has changed over...

10 months ago

29 minutes

Trends from the Trenches

Episode: 32 - Rémy Evard on Organizing Trials, Declining Resources, and AI Development

In this episode of Trends from the Trenches, host Stan Gloss discusses high-performance computing and its progress over the years with Rémy Evard, chief digital officer and head of technology at Memorial Sloan Kettering Cancer Center (MSK). They delve into the impact of cloud technology, the rapid development of AI (and the overexcitement around it), and the current industry-wide issue of maintaining healthcare quality during a time of declining resources. Evard also shares the responsibiliti...

1 year ago

25 minutes

Trends from the Trenches

Episode: 31 - Tom Plasterer on Going From Pharma to Start-Up, Graph Technology, and More

In this episode of Trends from the Trenches, host Stan Gloss speaks with industry veteran Tom Plasterer, managing director of life sciences innovation at XponentL Data. Plasterer shares his journey of how he became an industry leader, how his time at BG Medicine (then known as Beyond Genomics) helped him with his time at AstraZeneca, what graph technology is and its benefits, and why he returned to start-up companies with XponentL Data. He also gives advice based on his 20+ years of experienc...

1 year ago

29 minutes

Trends from the Trenches

Episode: 30 - Howard Jacob On Funding, Rare Diseases, and the Origins of ARCH

In this episode of Trends from the Trenches, host Stan Gloss speaks with Howard Jacob, vice president of genomics research at AbbVie. They discuss Jacob’s beginnings at AbbVie, data siloing and “my data vs. our data” issues, and the role of funding in plan execution and leadership support. Jacob also delves into the origins of the AbbVie R&D Convergence Hub (ARCH—winner of a 2023 Bio-IT World Innovative Practices Award), how they secured a sizable investment for its development, leveragin...

1 year ago

30 minutes

Trends from the Trenches

Episode 29 - Discussing Compute Research and Support in Academia With Ruth Marinshaw

Tune into this month’s episode of Trends from the Trenches, where host Stan Gloss and Ruth Marinshaw, CTO of Research Computing at Stanford University, talk about the accomplishments and challenges of supporting a diverse population of researchers in academia. Marinshaw also delves into building a reliable and trustworthy service, computational infrastructure as an essential tool for the lab, what FAIR data means to her at Stanford, and her thoughts on AI and its impact. Trends fro...

1 year ago

24 minutes

Trends from the Trenches

Episode: 28 - Bio-IT World Expo: Trends from the Trenches with Ari Berman

In this special episode of the Trends from the Trenches podcast, listen in on the Trends from the Trenches session at this year’s Bio-IT World Conference & Expo. Ari Berman, PhD, CEO of BioTeam, delivers a candid talk about the technologies driving data-intensive science, from the most worthwhile to the most overhyped to the most relevant. Learn what’s happening now with computing, storage, data transfer, networks, cloud, data science, machine learning, and more. Trends ...

1 year ago

51 minutes

Trends from the Trenches

Episode: 27 - Law to Biotech: Joseph La Barge on Starting a Company and the Future of Gene Therapy

In this month’s episode of Trends from the Trenches, host Stan Gloss speaks with Joseph La Barge. La Barge trained as an attorney but has spent most of his career building biotech businesses and securing funding. He shepherded Spark Therapeutics through its acquisition by Roche and has since joined Apertura Gene Therapy as CEO. He and Stan talk about the entrepreneurship journey, gene expression and capsid engineering, and Apertura’s future goals and projects. Links from this episode: &...

1 year ago

25 minutes

Trends from the Trenches

Episode: 26 - Embracing Change and Overcoming Resistance With Adama Ibrahim

Change can be scary, but it can also bring new opportunities and lead to growth and innovation. In this episode of Trends from the Trenches, host Stan Gloss from BioTeam and Adama Ibrahim, VP of Digital Strategy & Change Management at Novo Nordisk, delve into a conversation about humanity’s natural resistance to change, why it is important to overcome that resistance, and how change is the key to making progress. Ibrahim also shares how Novo Nordisk is supporting research organizations th...

1 year ago

33 minutes

Trends from the Trenches

Episode: 25 - Effective Data Management Strategies With Dr. Becky Upton

It’s no secret that the industry is drowning in data. That’s why data management strategies are needed now more than ever to speed up discoveries and bring new solutions to the market. In this episode of Trends from the Trenches, host Stan Gloss discusses data management strategies with Becky Upton, Ph. D., President of Pistoia Alliance. Dr. Upton shares how her organization is maximizing data management efficiency, such as delivering data at scale and harnessing AI to expedite R&D, and h...

1 year ago

22 minutes

Trends from the Trenches

Episode: 24 - Tom Miller Discusses How to Turn Your Research Into Your Own Company

Going from one field to the next can be a tricky thing to navigate. In this episode of Trends from the Trenches, host Stan Gloss speaks with Tom Miller, Co-Founder and CEO of Iambic Therapeutics, about his journey from academia as a professor at the California Institute of Technology to getting B-Round funding as the CEO of his own start-up. Miller discusses why he started his company, what inspired him to turn his research into an entrepreneurial venture, and how combining physics and data c...

1 year ago

25 minutes

Trends from the Trenches

Episode: 23 - Setting Global Wide Data Sharing Standards With Dr. Heidi Rehm

In this episode of Trends from the Trenches, host Stan Gloss speaks with Heidi Rehm, PhD, Chair Elect of the Global Alliance for Genomics and Health (GA4GH), about data sharing policies and standards that can advance both genomics and health. Rehm discusses the benefits of data sharing on a global scale, how organizations can reduce friction of people’s usage and adoption of standards, and successful examples of implementation. She also shares her thoughts on the future of AI, “data citizensh...

2 years ago

30 minutes

Trends from the Trenches

Episode: 22 - Exploring Generative AI And How It Can Improve Healthcare With Roche’s Bryn Roberts

In the latest episode of the Trends from the Trenches podcast, host Stan Gloss and Bryn Roberts, PhD, Global Head of Data & Analytics at Roche Information Solutions explore the Why and the How behind AI. What used to be “happily left a bit in the background” is now main stage thanks to everyone’s new interest in ChatGPT. Roberts recommends applying pharma’s Target Product Profiles (TPPs) to AI products as well: understanding what a tool or model should do, who its users are, how it will b...

2 years ago

32 minutes

Trends from the Trenches

Episode: 21 - Generative AI, Digital Twins, and the Future of Pharmaceutical Innovation

After the “magical moment of hope” when the first human genome was sequenced, Jeanne Kehren switched from veterinary medicine to the pharmaceutical industry. Today, she is the SVP of Digital & Commercial Innovation and CIO at Bayer Pharmaceuticals and works in various areas, including sustainability, digital health, and digital transformation. In this episode of Trends from the Trenches, host Stan Gloss speaks with Kehren about what drew her to pharmaceuticals, the potential future of dig...

2 years ago

42 minutes

Trends from the Trenches

Episode: 20 - Exploring the Benefits of AI

A few years ago, artificial intelligence was in its developmental stages. Today, it is widely used by various industries and several companies are exploring new ways to utilize its tremendous potential. In this episode of Trends from the Trenches, Stan Gloss speaks with Jarrod Anderson, Senior Director of Artificial Intelligence at ADM, who discusses prioritizing projects, selecting the best team members, and overcoming the biggest challenges that companies encounter in the machine learning s...

2 years ago

35 minutes

Trends from the Trenches

Episode: 19 - Research Consumers: Understanding How Data Can—And Can Not—Answer Questions about Customer Needs

In this episode of Trends from the Trenches, Stan Gloss speaks with Efosa Ojomo, director of the Global Prosperity Group at the Clayton Christensen Institute (CCI) and coauthor of The Prosperity Paradox: How Innovation Can Lift Nations Out of Poverty, about the parallels between consumption economy and life sciences research. Ojomo discusses how relying on data metrics does not necessarily provide full insight on what a consumer audience needs, why it is important to also look at non-consumer...

2 years ago

34 minutes

Trends from the Trenches

Episode: 18 - Bryn Roberts on Data Citizenship and Changing Data Culture

Bryn Roberts has spent thirty years in informatics and data, most recently at Roche and before that at AstraZeneca. Now as Global Head of Data and Analytics at Roche Information Solutions, Roberts applies his career-long learnings to the current era of data in life sciences, offering advice for building data citizenship, creating a FAIR data culture, and avoiding vendor lock-in. Links from this episode: Bryn Roberts: Reflections on Pharma’s Scientific Computing Journey Bio-IT Worl...

2 years ago

26 minutes