In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
All content for The Smartest Doctor in the Room is the property of Dr. Dean Mitchell and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
Ep. 194 - When Water Turns Toxic: Mold, Floods, and How to Protect Your Home with Joseph Reiss
The Smartest Doctor in the Room
42 minutes
1 month ago
Ep. 194 - When Water Turns Toxic: Mold, Floods, and How to Protect Your Home with Joseph Reiss
What should you do when water damage strikes—whether it’s a burst pipe, a flooded basement, or a slow leak you didn’t notice until it was too late? In this episode, Dr. Mitchell sits down with trusted mold inspector Joseph Reiss to unpack the essentials of mold prevention, testing, and remediation. They cover what to do in the first 24 hours after water damage, why carpets are mold magnets, how to safely contain and remove contaminated materials, and which testing methods actually help identify hidden mold.Joseph also shares insights on flood-proof home design, how to avoid costly mistakes, and what to look for in professionals who truly understand water and mold management. Whether you’re a homeowner, renter, or health-conscious listener, this conversation offers practical steps to protect your home—and your health—from toxic mold.
The Smartest Doctor in the Room
In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.