In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
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In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
Ep. 191 - COVID's Cognitive Shadow: Unraveling the Mystery of Brain Fog with Returning Guest Dr. Terry Harville
The Smartest Doctor in the Room
1 hour 12 minutes
2 months ago
Ep. 191 - COVID's Cognitive Shadow: Unraveling the Mystery of Brain Fog with Returning Guest Dr. Terry Harville
Brain fog—a term once absent from the medical lexicon—has become one of the most debilitating and puzzling symptoms of Long COVID. But what exactly is happening inside the body to cause this cognitive impairment? Is it just inflammation, or is there a more complex mechanism at play?In this episode, we sit down with leading immunologist Dr. Terry Harville, Medical Director of the Special Immunology Laboratory at the University of Arkansas for Medical Sciences. Dr. Harville takes us on a deep dive into the unique relationship between the SARS-CoV-2 virus and the human immune system, explaining why this zoonotic virus is so effective at causing long-term neurological issues. This isn't just about forgetfulness; it's a serious medical condition that could be a harbinger of something much worse.If you or someone you know is struggling with the cognitive effects of Long COVID, this episode is an essential listen, packed with scientific insights and actionable treatment strategies from an expert on the front lines.Visit apolloneuro.com and use code: smartmd at checkout to get your hands on the sleep wearable that Dr. Mitchell trusts.Need a certified mold inspector? Reach out to Joseph ReissPhone Number: 908-451-4592 Email: jprconsultants7929@gmail.com
The Smartest Doctor in the Room
In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
