In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
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In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
Ep. 189 - From Insecurity to Incision: A Top Plastic Surgeon's Unfiltered Advice
The Smartest Doctor in the Room
51 minutes
2 months ago
Ep. 189 - From Insecurity to Incision: A Top Plastic Surgeon's Unfiltered Advice
Ever looked in the mirror and wondered, What if I tweaked this? You’re not alone. Plastic surgery—once reserved for the rich and famous—is now a reality for everyday people seeking confidence and self-improvement. But how do you know if it’s right for you? And what separates a natural-looking result from a "wind tunnel face"?On this episode, host Dean Mitchell sits down with Dr. Robert Freund, a top Manhattan plastic surgeon, inventor of the Teardrop Breast Lift, and author of Cosmetic Breast Surgery and A More Beautiful You. From their shared high school days to their time at Brown University, Dean and Dr. Freund reunite for a candid conversation about the psychology of plastic surgery, teen procedures, the future of anti-aging and much more!Whether you’re considering a procedure or just fascinated by the intersection of medicine and art, this episode is packed with insider insights, ethical dilemmas, and a few wild stories from Dr. Freund (like the time he spent 16 hours reattaching a model’s fingertip).Visit apolloneuro.com and use code: smartmd at checkout to get your hands on the wearable that Dr. Mitchell trusts.Need a certified mold inspector? Reach out to Joseph ReissPhone Number: 908-451-4592 Email: jprconsultants7929@gmail.comVisit Dr. Mitchell's website here: https://www.mitchellmedicalgroup.com
The Smartest Doctor in the Room
In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
