In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
All content for The Smartest Doctor in the Room is the property of Dr. Dean Mitchell and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
Ep. 187 - Small Shifts, Big Results: Nutrition Hacks That Actually Stick with Mia Rigden
The Smartest Doctor in the Room
53 minutes
3 months ago
Ep. 187 - Small Shifts, Big Results: Nutrition Hacks That Actually Stick with Mia Rigden
In this episode of The Smartest Doctor in the Room, Dr. Mitchell sits down with renowned nutritionist, chef, and author Mia Rigden to explore her holistic approach to healthy eating for individuals and families. Mia shares her expert insights on balancing nutrition science with the emotional and practical aspects of food, offering actionable tips for sustainable wellness.Mia also opens up about her work with high-profile clients, her bestselling books FoodWise and The Well Journal, and her mission to make nutritious home cooking accessible through her Substack, Between Meals. Whether you're a busy parent, a fitness enthusiast, or just looking to feel better every day, this conversation is packed with science-backed wisdom you won’t want to miss!Visit miarigden.com for more practical insights!Need a certified mold inspector? Reach out to Joseph ReissPhone Number: 908-451-4592 Email: jprconsultants7929@gmail.comVisit Dr. Mitchell's website here: https://www.mitchellmedicalgroup.com
The Smartest Doctor in the Room
In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to yield better outcomes. We also look at prenatal folate fortification, the potential value of screening parents, the milk and autoimmunity connection in susceptible kids, and clear up myths around the common MTHFR polymorphism. Finally, we connect B12 status, homocysteine, and the different B12 forms used in practice. If you care about evidence based insights on autism research, neurodevelopment, and smart supplementation, this episode is a must listen.
