Can better sex really re-wire your brain for calm, confidence, and joy? Clinical sexologist Dr. Suzanne Mulvihill sits down with behavioral neuroscientist and certified sex therapist Dr. Nan Wise, author of the award-winning Why Good Sex Matters, to find out. Drawing on her groundbreaking fMRI studies, Dr. Wise explains how stimulating the clitoris, vagina, cervix and even the nipples lights up a tucked-away area she nicknames the “brain crotch,” creating a flood of feel-good chemicals that boost mood, ease pain, and sharpen focus.
What you’ll learn in plain language:
How pleasure rewires the nervous system
Regular sexual play (solo or partnered) increases blood flow, releases natural painkillers and endocannabinoids, and may even beat sudoku for brain health.
Why stress is the real bedroom villain
Chronic cortisol keeps bodies stuck in “fight or flight.” A simple trick; inhale, then exhale a little longer, helps shift the brain into safety so arousal can build.
Trauma-informed tips for reclaiming desire
From micro-dosing cannabis to gentle, curiosity-driven touch, Dr. Wise shares tools that foster neuroplasticity and dissolve old fear loops.
The orgasm gap (and why women can have longer, multiple peaks)
Her research shows female orgasms last longer and recruit wider brain networks than male orgasms, and you can train those pathways at any age.
The real story behind her late-career PhD, the surprising role of the vagus nerve, and why she calls pleasure “essential healthcare, not a luxury.” Press play and discover science-backed ways to feel safer, happier, and more connected in and out of the bedroom.
What really happens when a gentle shift in consciousness meets long-standing sexual blocks? In this episode of The Orgasm Hour, host Dr. Suzanne Mulvehill sits down with psychiatrist and philosopher Dr. Michael A. Schwartz to talk about cannabis, the brain’s own molecule DMT, and other mild mind-opening tools that can soften old trauma pathways and make space for pleasure.
Together they cover:
How Dr. Schwartz’s early research at the National Institutes of Health explored psychedelics before they were banned
Why cannabis is a “low-risk doorway” for women who struggle to let go and orgasm
What DMT is, and how your brain already makes it
Simple, safe steps for finding a trained guide and starting with tiny doses instead of going it alone
The science of dissolving rigid thought loops so new, healthy neural “roads” can form and support desire and connection
Press play to hear real stories, clear explanations, and practical advice on using supervised altered states to heal past hurt and unlock fuller intimacy.one small, mindful step at a time.
Ever wondered what actually happens when you bring a little cannabis into the bedroom? In this episode of The Orgasm Hour, clinical sexologist Dr. Suzanne Mulvehill sits down with researcher and sexologist Amanda Moser, whose nationwide study of more than 1,000 adults (ages 18-85) is the largest modern look at cannabis and intimacy. Together they break down the findings in plain language:
More spark, stronger finish: Over 70 percent of users felt higher desire and more intense full-body orgasms when they used cannabis before sex.
No performance drop-off: Men reported steadier erections and sometimes longer stamina, overturning the old “weed kills erections” myth.
Multiple-O magic & pain relief: Women were far likelier to reach multiple orgasms and found relief from pelvic pain and endometriosis cramps.
Amanda shares easy, beginner-friendly tips such as micro-dosing, infused lube, and homemade suppositories to enjoy the benefits without feeling “too high.” The duo also covers the golden rule of set and setting to keep anxiety away, plus simple communication moves that turn honest talk into foreplay and end the habit of faking pleasure.
Key Topics
How cannabis boosts desire, touch, taste, and overall pleasure
Starter guides to flower, edibles, concentrates, and lubes
Fixes for paranoia or past bad highs
Communication and consent tricks that deepen connection
Turning pleasure, not orgasm, into the main goal
Press play and discover scienc`e-backed, real-world ways to make intimacy feel better for you and your partner.
In this first episode of The Orgasm Hour, Dr. Suzanne Mulvehill, a clinical sexologist, and Dr. Sebastian Marincolo, author of The Art of the High, explore how cannabis can help unlock sexual pleasure and address orgasm difficulties. Dr. Mulvehill shares her personal journey and how cannabis played a crucial role in overcoming 30 years of sexual struggles. Dr. Marincolo brings his expertise in neurophysiology to discuss how cannabis impacts the brain, enhancing focus, emotional connection, and sensory experience.
Join them as they break down the science, share personal stories, and provide actionable insights on how cannabis can be used to enhance sexual health and personal well-being.
Key Topics:
Overcoming orgasm difficulties with cannabis
The science of cannabis and sexual pleasure
Personal stories and practical advice on cannabis use
Listen now to learn how cannabis can help you unlock new dimensions of pleasure.
The Orgasm Hour is a one-of-a-kind podcast hosted by Dr. Suzanne Mulvehill, a clinical sexologist, orgasmologist, and cannabis and female orgasm researcher who overcame a 30-year orgasm challenge—with the help of cannabis. This groundbreaking show explores the science of orgasm, the role of cannabis and sexual health, and real stories from women who have overcome orgasm difficulty—a struggle that affects nearly half of the female population but is rarely talked about openly.
Through in-depth interviews with scientists, researchers, and courageous women, we break the silence, bust myths, and dive into the psychological and physiological aspects of orgasm. Our mission is to unlock orgasm, empower healing, build sexual confidence, and inspire personal growth for women seeking to reclaim their pleasure.
Whether you're curious about female sexuality, battling your own orgasm issues, or interested in the intersection of cannabis and sex, this podcast offers research-based insight, hope, and tools for transformation.
Search terms: orgasm, female orgasm, cannabis and sex, orgasm difficulty, sexual wellness, women's pleasure, clinical sexology, sexual healing, sexual confidence, sex research, sexual empowerment