
If you’ve ever been told “your labs look fine” while your body loudly disagrees, this episode is for you. Lori sits down with Dr. Ali Chappell—nutrition scientist, reproductive endocrinology researcher, and registered dietitian—to reframe PCOS and beyond through the lens of the hormone most of us never test: insulin.
Together they unpack why A1C can look “normal” while fasting or post-meal insulin runs high; how that blocks ovulation, fuels acne and fatigue, and complicates pregnancy; and why menopause symptoms often escalate when insulin creeps up.
Ali breaks down low-insulin living without obsession or calorie counting, clears up the dairy/protein powder debate (yes, we’re looking at you, whey), and shares a simple script for getting your clinician to order the right labs.
You’ll walk away with practical food swaps, a clearer map of the metabolism–hormone connection, and—most importantly—more hope.
Chapters:
00:00 Introduction and Background
02:59 PCOS and Its Impact on Women's Health
06:07 Ali Chappell's Journey with PCOS
08:48 Understanding Insulin Resistance
11:56 The Role of Hormones in PCOS
14:58 Pregnancy and Insulin Levels
17:52 The Importance of Testing Insulin
20:48 Metabolic Issues and Their Consequences
23:49 The Connection Between Insulin and Ovulation
26:42 Conclusion and Key Takeaways
32:01 Understanding Insulin's Role
33:50 The Genetic Influence on Insulin Resistance
36:33 Diet and Insulin Resistance
40:53 The Impact of Insulin on Health
44:37 Natural Remedies for Insulin Resistance
47:54 Rethinking Nutrition: An Insulin-First Approach
55:56 Men's Health and Insulin Resistance
01:02:14 The Need for Insulin Testing
01:05:32 Understanding Insulin and Food Choices
01:08:38 The Impact of Insulin on Weight Management
01:11:29 Navigating Dairy and Its Effects on Insulin
01:20:25 Mental Health and PCOS: Finding Support
01:24:26 Communicating with Healthcare Providers
01:27:20 Introducing the PCOS App and Its Features