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The Hematology Podcast
Sanofi
24 episodes
2 weeks ago
Send us a text The integration of artificial intelligence (AI) into routine clinical practice is poised to revolutionize the diagnosis and treatment of hematologic diseases. AI-based models are already capable of automatically identifying cell populations including malignant cells, and facilitating early disease detection and prognosis. However, the efficacy of these tools depends on their correct application and interpretation, and hematologists need a basic understanding of machine learning...
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Health & Fitness
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Send us a text The integration of artificial intelligence (AI) into routine clinical practice is poised to revolutionize the diagnosis and treatment of hematologic diseases. AI-based models are already capable of automatically identifying cell populations including malignant cells, and facilitating early disease detection and prognosis. However, the efficacy of these tools depends on their correct application and interpretation, and hematologists need a basic understanding of machine learning...
Show more...
Health & Fitness
Episodes (20/24)
The Hematology Podcast
Transforming Hematology: The Power of AI
Send us a text The integration of artificial intelligence (AI) into routine clinical practice is poised to revolutionize the diagnosis and treatment of hematologic diseases. AI-based models are already capable of automatically identifying cell populations including malignant cells, and facilitating early disease detection and prognosis. However, the efficacy of these tools depends on their correct application and interpretation, and hematologists need a basic understanding of machine learning...
Show more...
1 month ago
41 minutes

The Hematology Podcast
ITP - Beyond platelet count
Send us a text Immune Thrombocytopenia (ITP) is an autoimmune disorder characterized by a low platelet count, which can lead to increased bleeding and bruising. In this episode, we will discuss the pathophysiology, clinical implications, and advancements in ITP. Our guest today, Professor Waleed Ghanima, is a renowned hematologist at Østfold Hospital and the University of Oslo in Norway. Prof. Ghanima has extensive experience in the field of hematology and has contributed significantly to res...
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3 months ago
45 minutes

The Hematology Podcast
High risk Multiple Myeloma - an update
Send us a text A new genomic definition of high-risk multiple myeloma (HR-MM) has been recently proposed by IMS/IMWG. The associated peer-reviewed publication is planned to be released in Spring 2025. Expert guest in this episode is Professor Monique Minnema, haematologist at the University Hospital in Utrecht in The Netherlands. She is an international expert with focus on diagnosis and treatment of malignant haematological diseases including Multiple Myeloma and Waldenström disease. She jus...
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3 months ago
41 minutes

The Hematology Podcast
TMA or Thrombotic microangiopathy - from Symptoms to Treatment
In this episode of The Hematology Podcast, we will delve into the complex world of thrombotic microangiopathy, or TMA. This condition encompasses a group of disorders characterized by small blood clots forming in the smallest blood vessels, leading to various complications. Diagnosing TMA can be particularly challenging due to its overlapping symptoms with other conditions and the need for specialized tests.In today’s episode, we have the honor of welcoming Professor Riitta Lassila to the stu...
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7 months ago
35 minutes

The Hematology Podcast
Decoding Multiple Myeloma genetic profile: The Power of Liquid Biopsy-Derived DNA
In this episode, we dive into the fascinating world of liquid biopsy-derived DNA as a revolutionary tool for comprehensive mutation profiling in multiple myeloma. This innovative approach offers a non-invasive way to analyse genetic alterations, potentially transforming how we diagnose and monitor this complex hematological cancer. Join us as we explore the promises and challenges of using liquid biopsies to decode the genetic landscape of multiple myeloma and its implications for personalize...
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8 months ago
21 minutes

The Hematology Podcast
Transfusion Dependent Thalassemia - the Severe Spectrum
In this episode, we focus on Thalassemia major, a severe form of the disease. In a previous episode, we discussed Thalassemia minor and intermedia with Professor Dr. Bart Biemond from Amsterdam UMC. Now, we will delve deeper into the challenges and treatments associated with Thalassemia major. Prof. Biemond is still with us to share his expertise.Professor Bart Biemond is a hematologist at the Amsterdam UMC in The Netherlands. Bart is head of the Hemoglobinopathy Expert Center and an active m...
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8 months ago
44 minutes

The Hematology Podcast
AML - from basics to future prospectives
Acute myeloid leukemia (AML) is a hematopoietic stem cell-derived myeloid malignancy characterized by manifold genetic aberrations and poor overall survival. Standard treatment for newly diagnosed fit AML patients is intensive chemotherapy. Relapse is, however, a challenge in more than 40% of AML patients. AML is also a disease with a large degree of individual heterogeneity, which creates challenges both for diagnostics and for developing targeted treatment options. Our guest is Björn G...
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1 year ago
30 minutes

The Hematology Podcast
Smoldering Multiple Myeloma – to treat or not to treat?
Smoldering multiple myeloma (SMM) is an intermediate condition that lies between Monoclonal gammopathy of undetermined significance (MGUS) and active multiple myeloma along the spectrum of clonal plasma cell proliferative disorders. Smoldering multiple myeloma may take years to become active multiple myeloma. In some cases, people who have this condition never develop active multiple myeloma. In this episode we have the pleasure of having the Norwegian haematologist Fredrik Schjesvold wi...
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1 year ago
26 minutes

The Hematology Podcast
Thalassemia - a blind spot
Thalassemia is a hereditary blood disorder, in which the synthesis of hemoglobin chains is impaired. Consequently, people with thalassemia minor may have slight to severe anemia which usually does not cause any problems. Thalassemia major in contrast is a severe disorder with need of transfusion and complications with iron overload. In this episode we will mainly discuss thalassemia minor and intermedia. Our guest today Professor Bart Biemond is a hematologist at the Amsterdam UMC ...
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1 year ago
40 minutes

The Hematology Podcast
Causes, symptoms and diagnosing ASMD – A rare lysosomal storage disorder
Today we will discuss a rare, inherited metabolic disorder known as ASMD, acid sphingomyelinase deficiency (or historically known as Niemann-Pick types A, A/B, and B). This genetic condition is very rare. It can be diagnosed, after suspicion, by different screening test. But symptoms may vary greatly, and has overlap with several other disorders, and the road to an accurate diagnosis can therefore be challenging. In today’s episode we have the pleasure of welcoming Professor David Cassim...
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1 year ago
38 minutes

The Hematology Podcast
MGRS- Monoclonal Gammopathy of Renal Significance
Monoclonal gammopathy of renal significance (MGRS) is a hemato-nephrological term referring to a heterogeneous group of kidney disorders characterized by direct or indirect kidney injury caused by a monoclonal immunoglobulin (MIg) produced by a B cell or plasma cell clone that does not meet current hematologic criteria for therapy. MGRS-associated kidney diseases are diverse and can result in the development of end stage kidney disease (ESKD). In this episode we have the pleasure of having th...
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1 year ago
25 minutes

The Hematology Podcast
Sickle cell disease - A hereditary blood disorder
Sickle cell disease (SCD) is a hereditary blood disorder, where red blood cells have the shape of a C or sickle - hence the name. Sickle cells have a shorter lifespan than normal red blood cells, which causes anemia. Additionally, sickle cells may block blood vessels, especially during infections, dehydration, stress or fatigue, causing complications for the patients. Our guest today Professor Bart Biemond is a haematologist at the Amsterdam UMC in The Netherlands. Bart is head of the He...
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1 year ago
1 hour 2 minutes

The Hematology Podcast
Extramedullary disease in Multiple Myeloma
Extramedullary disease (EMD) represents an aggressive form of multiple myeloma, characterized by the ability of myeloma cells to form tumors outside the bone marrow independently. Scientific research is continuously evolving, leading to discoveries of new treatments and improvements to current options. However, EMD in myeloma remains challenging from a therapeutic and biological perspective, and today the prognosis for patients with the disease is generally poor. Experts call for a bett...
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1 year ago
22 minutes

The Hematology Podcast
Recent findings in MGUS
Monoclonal gammopathy of undetermined significance, called MGUS, is a blood condition which indicates occurrence of clonal cells that secrete monoclonal immunoglobulins. MGUS as such, is not a harmful disease, and usually doesn’t require treatment. However, every year 1 percent of MGUS patients go on to develop myeloma or lymphoma. In this episode we have the pleasure of having the Icelandic Professor Sigurdur Kristinsson with us. He specialises in internal medicine and hematology. He ha...
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2 years ago
44 minutes

The Hematology Podcast
Waldenström Macroglobulinemia: a clinical update
Waldenström Macroglobulinemia is a rare type of non-Hodgkin lymphoma affecting B-cells. Waldenström Macroglobulinemia is characterised by high levels of circulating antibodies, immunoglobulin M, which is made and secreted by the cells involved in the disease. It is usually an indolent disease with no or limited symptoms. Therefore, patients with Waldenström Macroglobulinemia are often follow closely in “Watchful Waiting” until the disease and symptoms require onset of treatment. Our gues...
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2 years ago
43 minutes

The Hematology Podcast
Mental health during and after cancer treatment
Mental health includes our emotional, psychological and social well-being. A physical illness can have a severe impact on mental health. As health care professionals we often focus primarily on treatment and how to handle side effects and complications. The mental aspect of a disease is taking the back seat. How is mental health affected by a cancer diagnosis and treatment. And what does mental health mean for the patient's ability to cope with treatment and for the final outcome of treatment...
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2 years ago
40 minutes

The Hematology Podcast
Challenges in diagnosing Gaucher and other rare inherited metabolic disorders
In this episode we will discuss rare, inherited metabolic disorders in general, as well diseases such as Gaucher and other diseases. These genetic conditions are very rare. They can be diagnosed, after suspicion, by different screening test. But symptoms may vary greatly within these disorders and the road to an accurate diagnosis can therefore be challenging. Guest in this episode is Professor Allan Lund. He is a board-certified specialist in pediatrics with expert training in rare pediatric...
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2 years ago
37 minutes

The Hematology Podcast
Hemoglobinopathies
Hemoglobinopathies have previously been rare in the Nordic population but with increasing migration we now meet many patients with different types of thalassemias and hemoglobin variants. It is important to recognize these conditions and diagnosis can sometimes be challenging. In this episode we will meet an expert in hemoglobin disorders who will discuss classification and diagnostic procedures. Britta Landin is associate professor and senior consultant at the Karolinska University Hos...
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3 years ago
36 minutes

The Hematology Podcast
MRD as primary endpoint
Minimal residual disease (MRD) can today be evaluated in individual patient after treatment using various methods with high sensitivity. MRD indicates remaining malignant cells that could be a source of relapse of the disease. Could MRD also be used as an efficient endpoint in the design of new clinical studies? With help from Professor Ola Landgren, we will look into the crystal ball and discover what the future may hold for MRD.Host for the podcast is the Swedish hematologist Mats Mer...
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3 years ago
40 minutes

The Hematology Podcast
Minimal Residual Disease (MRD) - Cost vs Benefit
Detection of Minimal Residual Disease (MRD) is becoming more important in different fields of hematology including Multiple Myeloma. Over the past decades we’ve been able to improve the sensitivity of detecting minimal levels of MRD through innovations in molecular biology. But should MRD always be treated? Will it give a better outcome for the patient? And do the benefits outweigh the costs?”Host for the podcast is the Swedish hematologist Mats Merup. Special guest in this episod...
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3 years ago
27 minutes

The Hematology Podcast
Send us a text The integration of artificial intelligence (AI) into routine clinical practice is poised to revolutionize the diagnosis and treatment of hematologic diseases. AI-based models are already capable of automatically identifying cell populations including malignant cells, and facilitating early disease detection and prognosis. However, the efficacy of these tools depends on their correct application and interpretation, and hematologists need a basic understanding of machine learning...