Stomach acid is one of the most important digestive secretions in the body and it's still not well-understood by society. In fact, it's often demonized for the wrong reasons. Learn how important it is and how lack of it can lead to many digestive problems.
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Literature of PPI risks:
Nutrient deficiencies: Heidelbaugh JJ. Proton pump inhibitors and risk of vitamin and mineral deficiency: evidence and clinical implications. Ther Adv Drug Saf. 2013 Jun;4(3):125-33. doi: 10.1177/2042098613482484. PMID: 25083257; PMCID: PMC4110863
SIBO/IMO: Lo WK, Chan WW. Proton pump inhibitor use and the risk of small intestinal bacterial overgrowth: a meta-analysis. Clin Gastroenterol Hepatol. 2013 May;11(5):483-90. doi: 10.1016/j.cgh.2012.12.011. Epub 2012 Dec 24. PMID: 23270866
C. Difficile : Trifan A, Stanciu C, Girleanu I, Stoica OC, Singeap AM, Maxim R, Chiriac SA, Ciobica A, Boiculese L. Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis. World J Gastroenterol. 2017 Sep 21;23(35):6500-6515. doi: 10.3748/wjg.v23.i35.6500. PMID: 29085200; PMCID: PMC5643276
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