The Egg Factor

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The Egg Factor

Center For Human Reproduction

32 episodes

2 days ago

What happens after egg retrieval? For many patients, this part of the IVF process feels like a mystery. In this episode, Dr. Norbert Gleicher sits down with Dr. Cari Nicholas, CHR’s Embryology Lab Supervisor, to walk through the crucial days after retrieval. From fertilization to embryo development, they explain each step inside the lab, how embryologists make decisions about monitoring and transfer timing, and why lab quality plays such an important role in IVF outcomes. This behind-the-scen...

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Health & Fitness

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What happens after egg retrieval? For many patients, this part of the IVF process feels like a mystery. In this episode, Dr. Norbert Gleicher sits down with Dr. Cari Nicholas, CHR’s Embryology Lab Supervisor, to walk through the crucial days after retrieval. From fertilization to embryo development, they explain each step inside the lab, how embryologists make decisions about monitoring and transfer timing, and why lab quality plays such an important role in IVF outcomes. This behind-the-scen...

Show more...

Health & Fitness

Episodes (20/32)

The Egg Factor

Inside the Embryo Lab: What Happens to Your Embryos After Retrieval

What happens after egg retrieval? For many patients, this part of the IVF process feels like a mystery. In this episode, Dr. Norbert Gleicher sits down with Dr. Cari Nicholas, CHR’s Embryology Lab Supervisor, to walk through the crucial days after retrieval. From fertilization to embryo development, they explain each step inside the lab, how embryologists make decisions about monitoring and transfer timing, and why lab quality plays such an important role in IVF outcomes. This behind-the-scen...

2 days ago

48 minutes

The Egg Factor

Remembering Them: Creating Rituals and Meaning Around Infant or Pregnancy Loss

Pregnancy and infant loss are often accompanied by silence, yet healing requires space for remembrance. In this episode, Dr. Sonia Gayete explores how rituals, both private and shared, can help families honor their babies and create meaning after loss. From simple acts like lighting a candle to community events and creative expressions, Dr. Gayete shares ways that families can find comfort, connection, and healing in remembrance. Brought to you by the Center for Human Reproduction (CHR) on th...

1 week ago

7 minutes

The Egg Factor

Medical Miscarriage: What You’re Not Told About Recurrent Loss and Testing Options

When pregnancy loss happens more than once, it is not "just bad luck." It is a medical condition that deserves answers. In this episode, Dr. Norbert Gleicher explains why recurrent pregnancy loss is often overlooked, what standard care misses, and which diagnostic tests can uncover hidden causes. From immune factors to hormonal imbalances, Dr. Gleicher highlights why a one-size-fits-all approach does not work and how deeper investigation can bring hope for the future. Brought to you by the Ce...

2 weeks ago

10 minutes

The Egg Factor

Trying Again After Loss: How to Navigate Fear, Hope, and Healing

Pregnancy loss leaves behind not just grief, but difficult questions about when to try again. In this episode, Dr. David Barad explores the emotional and medical realities of pursuing pregnancy after loss. From navigating fear and uncertainty to holding space for hope, Dr. Barad offers compassionate insight and practical guidance for those considering their next steps on the path to parenthood. Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. ...

3 weeks ago

6 minutes

The Egg Factor

Honoring Grief: What to Say (and What Not to Say) After Pregnancy or Infant Loss

Grief after pregnancy or infant loss is often met with silence or words that miss the mark. In this episode, host Dr. Norbert Gleicher speaks with Dr. Simone Tomasi, consulting psychiatrist at CHR, about the power of language in supporting those who have experienced loss. Together, they explore what to say (and what not to say), how compassion can help families feel seen, and why holding space for grief is an essential part of healing. Brought to you by the Center for Human Reproduction...

1 month ago

24 minutes

The Egg Factor

The long-term health effects of PCOS

In this episode, CHR’s physicians take a closer look at the long-term health effects of PCOS and what patients need to know beyond their 20s and 30s. At CHR, we believe in looking beyond short-term fertility treatment. PCOS is a lifelong condition that requires awareness, individualized care, and ongoing support. Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the f...

1 month ago

6 minutes

The Egg Factor

Breaking down SART outcomes

Success rates are one of the most common ways fertility clinics are compared—but what do the numbers actually mean? In this episode of The Egg Factor, CHR’s Medical Director Dr. Norbert Gleicher and Associate Medical Director Dr. David Barad break down the latest SART (Society for Assisted Reproductive Technology) outcome data. Together, they unpack: How SART collects and reports IVF outcomes across U.S. clinicsWhy success rates can be misleading—especially for patients over 40 or those with ...

1 month ago

14 minutes

The Egg Factor

The Hormone Reset: Understanding the Endocrine and Immune Shifts of Perimenopause and Their Fertility Implications

As fertility declines with age, it's not just about egg quantity—it's about the entire hormonal and immune environment surrounding the ovaries. In this episode of The Egg Factor, CHR’s physicians break down the nuanced changes that happen in the late 30s and 40s, including shifts in estrogen, testosterone, and DHEA levels—and how these changes impact ovarian function and embryo quality. Listen now on Spotify, Apple Podcasts, or wherever you get your podcasts. Brought to you by the Center for ...

1 month ago

17 minutes

The Egg Factor

Lean PCOS & Low Androgens: The Overlooked Diagnosis Sabotaging Fertility Over 35

Not all PCOS is created equal. In this solo episode of The Egg Factor, CHR’s Medical Director Dr. Norbert Gleicher dives into one of the most misunderstood—and frequently missed—diagnoses in reproductive medicine: lean PCOS with low androgens, also known as D-phenotype PCOS. Often overlooked because these patients don’t fit the “typical” PCOS profile, women with D-phenotype are usually thin, have regular periods, and no obvious signs of excess androgens. But as they age—especially after 35—th...

2 months ago

15 minutes

The Egg Factor

Nutrition vs. Medication: Can Diet Alone Influence IVF Success in Women Over 40?

In this solo episode of The Egg Factor, Dr. Norbert Gleicher, Medical Director of CHR, unpacks the complex relationship between nutrition, inflammation, insulin resistance, and reproductive outcomes in women over 40. Drawing on decades of clinical and research experience, Dr. Gleicher dives into how specific micronutrients and metabolic factors influence egg quality, implantation, and miscarriage risk. Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg ret...

2 months ago

13 minutes

The Egg Factor

The Fertility Cliff Reconsidered: What the Data Really Shows for Women 40 and Over

We’ve all heard it: after 40, your chances of conceiving with your own eggs plummet. But is the data behind the so-called "fertility cliff" as clear-cut as it seems? In this episode of The Egg Factor, CHR's Dr. Norbert Gleicher unpacks research, clinical experience, and patient outcomes to challenge the mainstream narrative. He explores how fertility statistics have been widely misinterpreted, why donor eggs are often recommended too quickly, and what ovarian potential really looks like in wo...

2 months ago

11 minutes

The Egg Factor

What Does It Really Mean When Ovaries Age?

We often hear about the biological clock—but what does “ovarian aging” really mean? In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad explain the science behind ovarian aging, how it differs from chronological age, and what it means for fertility—especially for women in their late 30s, 40s, or those diagnosed with low ovarian reserve. Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience an...

2 months ago

16 minutes

The Egg Factor

Inside the Fertility Lab: What Patients Need to Know About Embryos, Grading, & Genetic Testing

What really happens behind the microscope? In this episode of The Egg Factor, Dr. Norbert Gleicher, Dr. David Barad, and world-renowned embryologist Dr. David Albertini take you inside the fertility lab to demystify some of the most misunderstood parts of the IVF process. They break down: -How embryos are graded—and what those grades actually mean -What exactly about morphology is important -The truth about PGT-A (and whether it improves your chances) -How many times can you freeze a human ...

3 months ago

21 minutes

The Egg Factor

The Three Person Embryo: Science, Ethics & the FDA Ban

In this episode of The Egg Factor, Dr. Norbert Gleicher, Dr. David Barad, and Dr. David Albertini unpack one of the most controversial topics in reproductive medicine today: Three-Person IVF—also known as mitochondrial replacement therapy. Together, they break down: - What “three-parent embryos” actually are - The science behind mitochondrial transfer - Why this technique is currently banned by the FDA - And the serious ethical and biological concerns it raises While headlines might portra...

3 months ago

14 minutes

The Egg Factor

Fertility Q&A: Day 3 FETs & Chromosomal Concerns Over 40 with Dr. David Barad and Dr. Norbert Gleicher

In this listener-driven Q&A episode of The Egg Factor, CHR’s Dr. Norbert Gleicher and Dr. David Barad answer two critical questions from our patient community. First up: If you're doing a Day 3 frozen embryo transfer (FET) and had no choice—should you opt for a medicated or modified natural cycle? Then, the doctors tackle a question that weighs heavily on many: What are the most common chromosomal abnormalities seen in women 40 and older, and how do they impact fertility treatment? Known ...

3 months ago

14 minutes

The Egg Factor

Fertility and the Law: What Legislation Really Means for IVF

With headlines swirling about legal threats to IVF and fertility treatment, many patients are left feeling anxious and uncertain. In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad break down the recent legislative developments—and what they actually mean for fertility care in the U.S. Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the fore...

3 months ago

12 minutes

The Egg Factor

Nutrition, Egg Quality, and IVF for Women Over 40: A Conversation with Prima Pharmacy

If you’ve been through multiple IVF cycles without answers—or you’re over 40 and feeling dismissed—this episode is for you. In this candid conversation with Prima Pharmacy, Dr. Norbert Gleicher, Medical Director at the Center for Human Reproduction (CHR), breaks down what really matters in later-in-life fertility care. From the role of immune health and egg quality to anti-inflammatory diets and the truth about “unexplained infertility,” he shares the insights that have helped thousands of pa...

4 months ago

42 minutes

The Egg Factor

Redefining the Odds: Fertility Treatment for Women Over 40

In this empowering episode of The Egg Factor, CHR's Dr. Norbert Gleicher and Dr. David Barad discuss why fertility care for women over 40 demands a completely different approach—and how CHR is leading the way. With a mean patient age of 44, CHR has the oldest IVF patient population of any clinic in the U.S., and possibly the world. The doctors share what makes these patients—and their care—so unique, the protocols that have helped many achieve success after being told it was too late, and why...

4 months ago

11 minutes

The Egg Factor

Breaking Barriers: Fertility Access for HIV+ Patients

In this special Pride Month episode of The Egg Factor, Dr. David Barad and Dr. Norbert Gleicher discuss one of CHR’s proudest milestones: helping HIV+ patients safely and successfully pursue parenthood. Hear the behind-the-scenes story of how CHR helped advocate for a groundbreaking exception to New York State law, allowing HIV-positive individuals to use their sperm in gestational surrogacy. From partnering with the Bedford Research Foundation’s SPAR program to championing updated guidelines...

4 months ago

7 minutes

The Egg Factor

Why Is Infertility on the Rise? Unpacking the Trends with CHR Experts

In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad of the Center for Human Reproduction dig into the social shifts and biological realities contributing to the global rise in infertility. From delayed parenthood and environmental toxins to male fertility decline and autoimmune conditions, they explore the many layers of a complex issue. Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience a...

4 months ago

7 minutes