If you were given some of the worst news in the world, wouldn’t you expect your doctors to use every tool available? What if one of those tools could save millions of lives—and the science is already here? The world’s largest medical cannabis and cancer study—10,000 papers, ranked in the top 5% globally—shows overwhelming evidence that cannabis has medical benefits. If fully embraced, its impact on patients and medicine could be transformative. As science continues to unfold, sometimes it takes skeptics to dive deep and uncover what’s truly there, even when powerful interests push back. This week we sit down with Ryan Castle, Research Director at Whole Health Oncology Institute, to discuss: Medical cannabis: efficacy, placebo, and why it matters less than you think How this study is being used in rescheduling efforts How vested interests fuel anti-cannabis research Chapters 00:00 Introduction to Medical Cannabis Research 03:06 Ryan Castle's Journey into Cannabis Research 05:58 The Meta-Analysis Process Explained 09:00 Understanding the Data and Its Implications 11:54 Skepticism and the Shift in Perspective 15:01 Consensus in Medical Cannabis Research 18:04 Nuances in Cancer Treatment and Cannabis 20:55 Biomarkers and Inflammatory Responses 22:56 Exploring Cannabis and Cancer Outcomes 29:37 Bridging the Gap: Patient-Reported Outcomes 35:32 The Future of Medical Cannabis Research 45:34 The Cancer Playbook: Empowering Patients Summary In this episode, Bryan Fields and Kellan Finney engage with Ryan Castle, Research Director at Whole Health Oncology Institute, to explore the evolving landscape of medical cannabis research. Ryan shares his journey from skepticism to advocacy, detailing the extensive meta-analysis he conducted on the efficacy of cannabis in treating various symptoms and conditions, particularly in oncology. The conversation delves into the challenges of measuring effectiveness, the importance of patient-reported outcomes, and the need for a shift in medical perspectives towards cannabis as a legitimate treatment option. Ryan emphasizes the potential impact of policy changes and the importance of transparency in research, while also discussing the Cancer Playbook initiative aimed at empowering patients with data-driven insights. Takeaways Ryan Castle initially set out to prove that cannabis doesn't work. His extensive research revealed that cannabis is effective for a wide range of conditions. The meta-analysis included over 10,000 studies and 800,000 data points. Cannabis showed efficacy not just for symptoms but also for cancer treatment. Patient-reported outcomes are crucial for understanding cannabis effectiveness. The study found that cannabis can help reduce opioid dependency. There is a significant need for a shift in medical perspectives on cannabis. Transparency in research is essential for building trust in findings. The health impact assessment could reveal the broader benefits of cannabis. The Cancer Playbook initiative aims to empower patients with data-driven insights. Guest Links https://wholehealthoncologyinstitute.com/ Our Links Bryan Fields on Twitter Kellan Finney on Twitter The Dime on Twitter Extraction Teams: Want to cut costs and get more out of every run? Unlock hidden revenue by extracting more from the same input—with Newton Insights. At Eighth Revolution (8th Rev), we provide services from capital to cannabinoid and everything in between in the cannabinoid industry. The Dime is a top 5% most shared global podcast The Dime is a top 10 Cannabis Podcast The Dime has a New Website. Shhhh its not finished. 🎥 YouTube:  The Dime 📸 Instagram:  The Dime https://www.newton-insights.com/