Ziprasidone and quetiapine. One goes better fast, one slow. Also the mystery of ghost pills, and a research update on pramipexole.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5528-how-to-start-a-psych-medication-iv)Published On: 09/08/2025Duration: 13 minutes, 47 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

The FDA just approved the cyclobenzaprine (Tonmya, Flexeril) for fibromyalgia. We look at three risks that medication raises in psychiatry.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5523-a-new-fda-approval-brings-new-psychiatric-risks)Published On: 09/01/2025Duration: 16 minutes, 42 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

The FDA just approved Ketarx for surgical pain, but the company has its eyes on depression.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5511-a-new-ketamine)Published On: 08/15/2025Duration: 18 minutes, 30 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Meds that require special skill to start: Atomoxetine and prazosin, plus a new FDA warning on stimulants.CME: (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5478-copy-of-how-to-start-a-psych-medication) Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5497-how-to-start-a-psych-medication-iii)Published On: 08/18/2028Duration: 08 minutes, 28 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Meds that require special skill to start: Antipsychotics, Cobenfy, and a research update on antidepressant metabolism in Asians.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5478-copy-of-how-to-start-a-psych-medication)Published On: 08/11/2025Duration: 12 minutes, 19 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Before you cook, oil the pan; before you plant that spring lawn, aerate the soil. Before you start a psych med, these are six things you need to have in place.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5476-how-to-start-a-psych-medication)Published On: 08/04/2025Duration: 13 minutes, 18 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

We interview psychoanalyst William Meyer on a therapeutic approach to postpartum depression.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5461-therapy-for-postpartum-depression)Published On: 07/28/2025Duration: 14 minutes, 18 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

We look at how often postpartum depression converts to bipolar, and what that means for treatment.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5451-bipolar-in-the-postpartum)Published On: 07/21/2025Duration: 10 minutes, 27 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Today, we are focusing on how families are responding mentally and emotionally to disaster, and how children process loss when a parent or caregiver dies.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5447-grief-parenting-and-recovery-after-a-disaster)Published On: 07/17/2025Duration: 19 minutes, 48 secondsJoshua Feder, MD, and Mara Goverman, LCSW, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Brexanolone has quietly exited the pharmaceutical stage, and we look at what that means for its stand-in, zuranolone (Zurzuvae), in postpartum depression. CME: (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5442-environmentally-induced-narcissism)Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5445-so-long-brexanolone)Published On: 07/14/2025Duration: 12 minutes, 50 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

We explore the DSM-style criteria for Hubris Syndrome, a variation of narcissism that can be induced by too much power and adoration.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5442-environmentally-induced-narcissism)Published On: 07/07/2025Duration: 11 minutes, 44 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Two ways to approach narcissism in therapy, and how AI can ramp up the problem. CME: (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5440-psychopharm-secrets-coming-off-meds)Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5441-narcissism)Published On: 06/30/2025Duration: 10 minutes, 44 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

There’s a hidden placebo response to watch for when patients stop meds on their own.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5440-psychopharm-secrets-coming-off-meds)Published On: 06/23/2025Duration: 13 minutes, 43 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

We look at a hidden placebo effect that can confuse the picture when starting a medication.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5438-psychopharm-secrets-starting-meds)Published On: 06/16/2025Duration: 13 minutes, 22 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Artificial Intelligence is full of medical information. Here’s how to use it wisely. CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5389-ai-in-practice)Published On: 06/09/2025Duration: 18 minutes, 48 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

A teen is using substances—how do you decide what kind of treatment makes sense? Outpatient therapy? A more structured program? We’re breaking it down.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5384-teen-substance-use-choosing-the-right-care)Published On: 06/02/2025Duration: 20 minutes, 08 secondsJoshua Feder, MD, and Mara Goverman, LCSW, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Imagine turning 18 and suddenly being responsible for every major life decision. Yikes. That includes medical, financial, and personal, without guidance. For many young adults with developmental disabilities, these transitions can be overwhelming. How can clinicians and families provide the right level of support while respecting autonomy or at least encouraging it? That's what we're exploring today.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5380-empowering-decision-making-in-developmental-disabilities)Published On: 05/25/2025Duration: 13 minutes, 06 secondsJoshua Feder, MD, and Mara Goverman, LCSW, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Many families struggle to find OCD treatment for their children. Specialty-trained therapists are limited, and wait lists are usually long. Online therapy is an option, but how well does it work? Today, we discuss a study that examines online cognitive behavioral therapy with exposure and response prevention for kids with OCD.CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5372-expanding-access-to-ocd-treatment)Published On: 05/19/2025Duration: 11 minutes, 16 secondsJoshua Feder, MD, and Mara Goverman, LCSW, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Today, we’re tackling a big question: How young is too young to treat children with medication for ADHD?CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5363-preschoolers-and-stimulants-when-is-medication-the-right-call-for-adhd)Published On: 05/12/2025Duration: 14 minutes, 36 secondsJoshua Feder, MD, and Mara Goverman, LCSW, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

MTHFR is a genetic test that aims to clarify who will respond to methylfolate in depression. But is it worth testing for?CME: Take the CME Post-Test for this Episode (https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5362-should-you-test-mthfr)Published On: 05/05/2025Duration: 18 minutes, 52 secondsChris Aiken, MD, and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.