On this episode of The Advancing Healthcare Innovation Show, host Michael Stamatinos sits down with James Wallace, innovator, executive, author, and senior researcher at Harvard Business School for an in-depth conversation about the future of healthcare, the rise of precision medicine, and the role of AI in reshaping how we deliver care.James has built a career at the crossroads of science, technology, and healthcare, and his work spans multiple industries. He is the Founder of The Wellesley Group, a senior researcher at Harvard Business School, and the former CEO of DecisionRx, a company that integrated pharmacogenomics, lab data, and patient engagement into a single precision medicine platform. He is also the author of Precision Medicine: AI and the Science of Personalized Healthcare, a book that blends compelling patient stories with rigorous analysis to show how personalized care can address the healthcare system’s triple crisis of cost, access, and quality.But James’s story doesn’t stop there. His career has also included leadership roles at AmeriLife, TWG Capital, and Anthem, along with a remarkable detour into aerospace as Vice President of Business Development at SpaceX, where he managed a 52-mission launch manifest during a pivotal growth phase. Today, his research and advisory work extend across five continents through the GENiE Group, influencing how healthcare policy and delivery models are evolving worldwide.This episode is not just about frameworks or technology. It’s about the people behind the change. James shares stories from his book including patients like Michael, Jennifer, Emily, Amy, and Susan that bring the concepts of precision medicine to life. These narratives reveal what’s at stake for real people, while offering a roadmap for leaders ready to move beyond “one-size-fits-all” medicine.What You’ll Learn in This Episode:* The personal journey of James Wallace: from Bain & Company to Anthem, to founding The Wellesley Group, to leading DecisionRx, and even a chapter at SpaceX* Behind the book: why James wrote Precision Medicine: AI and the Science of Personalized Healthcare, and the patient stories that made it unforgettable* How precision medicine is uniquely positioned to solve healthcare’s cost, access, and quality crisis* The promise and pitfalls of AI in healthcare...what’s real, what’s hype, and what leaders need to focus on now* Lessons from private equity boardrooms on scaling healthcare innovations without losing sight of impact* Insights from global healthcare systems and what the U.S. can learn from models that are already working overseas* Why policy conversations matter just as much as technology when it comes to making precision medicine real* Leadership lessons James carried from SpaceX into healthcare and how thinking like a rocket company can help health systems move faster* The one challenge James issues to healthcare leaders, innovators, and investors what he believes they should do tomorrow to create ripple effects across the system📣 LIKE, COMMENT & SUBSCRIBEIf this conversation moved you, challenged your thinking, or sparked an idea, share it with someone who needs to hear it. Subscribe for more episodes with healthcare leaders who are not just thinking differently, they’re building differently.About the ShowThe Advancing Healthcare Innovation Show is hosted by Michael Stamatinos, a nationally recognized connector, strategist, and advocate for innovation with purpose. Each week, Michael interviews healthcare leaders who are driving meaningful change—highlighting stories of access, resilience, equity, and transformation.The AHI Show started with the idea of wanting to highlight stories of what healthcare innovation truly looks like in action. Our mission, highlight real people who are really innovating within healthcare. Guests include healthcare entrepreneurs, providers, payers, and professionals from the investment community. We showcase little wins as well as v
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