Sickle cell anemia is a genetic disorder caused by a mutation in the hemoglobin gene (HBB), resulting in the production of abnormal hemoglobin (HbS). The sickled red blood cells are less effective at transporting oxygen, break down prematurely (causing anemia), and can block blood vessels, leading to pain and organ damage.

In this Episode Dr. Auma takes us throgh the Pathophysiology and the Management like:

Pain relief during crises (NSAIDs, opioids)

Hydroxyurea to reduce crises

Blood transfusions to manage anemia

Vaccinations and antibiotics to prevent infections

Hydration and oxygen therapy during crises

Overall, treatment focuses on alleviating symptoms, preventing complications, and improving quality of life.