In this episode of The Deep Dive, supported by RevGenetics, we explore how the world’s oldest people may hold the key to treating one of the rarest aging diseases, Hutchinson-Gilford Progeria Syndrome (HGPS).
HGPS is caused by a mutation in the LMNA gene, which produces a toxic protein called progerin that causes rapid aging. However, super centenarians, people who live beyond 110 years, have a special LMNA gene variant that helps protect their cells from progerin damage.
Researchers now believe this longevity variant could help protect children with HGPS from early heart problems, especially diastolic dysfunction, an early sign of heart failure. This study offers new hope for immediate heart protection and a better understanding of how some humans naturally resist aging.
Join us as we explore the connection between genetic longevity and progeria research, and what it could mean for longer, healthier lives.
Supported by RevGenetics – Science-Based Supplements For Healthy Aging
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Referenced Study:
Supercentenarian LMNA Variant and HGPS – Nature Cell Discovery
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#Progeria #HGPS #LongevityResearch #SuperCentenarians #LMNAGene #RevGenetics #HealthyAging #AntiAgingScience #HeartHealth #Progerin #GeneticLongevity #CellularResilience #LongevityPodcast #AgeReversal #ScienceBreakthroughs #CardiovascularResearch #LongevityPotential #DeepDivePodcast #RevGeneticsSupport