SLAS Technology Authors Talk Tech

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SLAS Technology Authors Talk Tech

Dave Pechter, M.S.M.E.

29 episodes

2 months ago

In this episode, podcast host David Pechter invites SLAS Technology featured author Dr. Hossam Ibrahim (University College Dublin) to discuss his research on the dissemination of tumor cells to understand the mechanisms behind cancer metastasis. Tune in to hear how the research team developed a migration assay combining 3D models and a physiologically relevant extracellular matrix. Hear about the unique challenges faced by researchers while orchestrating the application of 3D technologies wit...

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In this episode, podcast host David Pechter invites SLAS Technology featured author Dr. Hossam Ibrahim (University College Dublin) to discuss his research on the dissemination of tumor cells to understand the mechanisms behind cancer metastasis. Tune in to hear how the research team developed a migration assay combining 3D models and a physiologically relevant extracellular matrix. Hear about the unique challenges faced by researchers while orchestrating the application of 3D technologies wit...

Show more...

Episodes (20/29)

SLAS Technology Authors Talk Tech

Author Interview: Utilizing 3D Technologies to Study Tumor Cell Dissemination

In this episode, podcast host David Pechter invites SLAS Technology featured author Dr. Hossam Ibrahim (University College Dublin) to discuss his research on the dissemination of tumor cells to understand the mechanisms behind cancer metastasis. Tune in to hear how the research team developed a migration assay combining 3D models and a physiologically relevant extracellular matrix. Hear about the unique challenges faced by researchers while orchestrating the application of 3D technologies wit...

2 years ago

13 minutes

SLAS Technology Authors Talk Tech

Behind the Special Issue: Single Cell Analysis Technologies

Behind the Special Issue: Join podcast host David Pechter as he invites Joseph de Rutte (Partillion Bioscience) to discuss the paper: “Sorting single-cell microcarriers using commercial flow cytometers”. This research was featured in the recent SLAS Technology special issue, Single Cell Analysis Technologies. Listen in as they discuss the unique formation of microscopic, bowl-shaped containers they call nanovials, and the applications of these cell carriers in flow cytometry for functional si...

3 years ago

16 minutes

SLAS Technology Authors Talk Tech

Assay Guidance Manual: Technologies that Matter

Join SLAS Podcast Host Dave Pechter as he welcomes R. Graham Cooks, Ph.D. (Purdue University) and Nicolás M. Morato (Purdue University) to discuss their research, featured in the latest Issue of SLAS Technology. They are joined by Nathan P. Coussens, Ph.D. (Frederick National Laboratory for Cancer Research), guest editor of this special issue. Together, they discuss the article “Automated High-Throughput System Combining Small-Scale Synthesis with Bioassays and Reaction Screening”. Thi...

3 years ago

20 minutes

SLAS Technology Authors Talk Tech

In Conversation: SLAS Editors on Open Access

Join Jill Hronek, SLAS Director of Marketing and Communications, and Ally Jump, SLAS Publishing Manager, as they speak with SLAS Discovery and SLAS Technology’s respective Editors-in-Chief, Robert M. Campbell, Ph.D., (Twentyeight-Seven Therapeutics, Boston, MA USA) and Edward Kai-Hua Chow, Ph.D., (National University of Singapore, Singapore) about SLAS’s new Open Access model for the Society’s two peer-reviewed journals. Beginning January 1, 2022 both SLAS Discovery and SLAS Techn...

4 years ago

13 minutes

SLAS Technology Authors Talk Tech

Low-Cost 3D Bioprinters: State of The Market and Observed Future Trends

Recent innovations and accelerating market availability have led to tremendous growth in demand for affordable 3D bioprinter hardware. Podcast host David Pechter invites SLAS Technology August cover authors Roman Voronov and Anh Tong of the New Jersey Institute of Technology to discuss their review of the market, and their predictions about where it is going. This month's SLAS Technology cover article provides essential insights to researchers entering a market flooded with different ty...

4 years ago

15 minutes

SLAS Technology Authors Talk Tech

Discussion on SLAS Featured Talk: Harnessing Synthetic Biology and Deep Learning to Fight Pathogens

Podcast Editor David Pechter hosts Jim Collins of the MIT Department of Biological Engineering to discuss his talk on the harnessing of deep learning to fight pathogens. The future of medicines using synthetic biology is a rapidly expanding field, with applications including engineered diagnostics, gene and cell therapies, and the deployment of mRNA vaccines to fight the COVID-19 pandemic. The application of deep learning is accelerating this research, facilitating rapid candidate...

4 years ago

16 minutes

SLAS Technology Authors Talk Tech

Special Collection: AI in Process Automation

Volume 26 Issue 1, February 2021 Dave Pechter discusses the February SLAS Technology Special Collection AI in Process Automation with Guest Editor Cenk Undey (Amgen), which includes the following papers: Artificial Intelligence Effecting a Paradigm Shift in Drug Development by Masturah Bte Mohd Abdul RashidArtificial Intelligence (AI) to the Rescue: Deploying Machine Learning to Bridge the Biorelevance Gap in Antioxidant Assays by Sunday Olakunle Idowu and Amos Akintayo FatokunDeep Lear...

4 years ago

12 minutes

SLAS Technology Authors Talk Tech

Special Collection: Advances in Technology to Address COVID-19

Volume 25 Issue 6, December 2020 Dave Pechter discusses the December SLAS Technology Special Collection Advances in Technology to Address COVID-19 with Associate Editor Pak Kin Wong (The Pennsylvania State University), which includes Professor Wong's review Advances in Viral Diagnostic Technologies for Combating COVID-19 and Future Pandemics.

4 years ago

9 minutes

SLAS Technology Authors Talk Tech

Role of Digital Microfluidics in Enabling Access to Laboratory Automation and Making Biology Programmable

Volume 25 Issue 5, October 2020 Dave Pechter discusses with Varun Bhaskar Kothamachu, Ph.D. (Head of Product, Digi.Bio) & Sabrina Zaini (Head of Operations, Digi.Bio) their featured research article, "Role of Digital Microfluidics in Enabling Access to Laboratory Automation and Making Biology Programmable."

5 years ago

13 minutes

SLAS Technology Authors Talk Tech

Special Issue: Carbohydrate Structure Analysis: Methods and Applications

SLAS Technology 25.4 August 2020

5 years ago

13 minutes

SLAS Technology Authors Talk Tech

Traceable Impedance-Based Dispensing and Cloning of Living Single Cells and Impedance-Based Single-Cell Pipetting

Volume 25 Issue 3, June 2020 Dave Pechter discusses with Georges Muller & Yann Barrandon their two featured research articles, "Traceable Impedance-Based Dispensing and Cloning of Living Single Cells" and "Impedance-Based Single-Cell Pipetting." Traceable Impedance-Based Dispensing and Cloning of Living Single Cells: Single-cell cloning is essential in stem cell biology, cancer research, and biotechnology. Regulatory agencies now require an indisputable proof of clonality that current t...

5 years ago

13 minutes

SLAS Technology Authors Talk Tech

CURATE.AI: Optimizing Personalized Medicine with Artificial Intelligence

Volume 25 Issue 2, April 2020 Dave Pechter discusses with Agata Blasiak & Theodore Kee regarding their article, "CURATE.AI: Optimizing Personalized Medicine with Artificial Intelligence." The clinical team attending to a patient upon a diagnosis is faced with two main questions: what treatment, and at what dose? Clinical trials’ results provide the basis for guidance and support for official protocols that clinicians use to base their decisions upon. However, individuals rarely de...

5 years ago

19 minutes

SLAS Technology Authors Talk Tech

Special Issue: Flexible Analytical Devices for Point-of-Care Testing

Volume 25 Issue 1, February 2020 Dave Pechter discusses with Hideaki Tsutsui & Peter Lillehoj regarding February's Special Issue. Over the last decade, flexible analytical devices have received considerable attention in both academia and industry. Compared to conventional analytical devices which are generally made from rigid materials, such as silicon, glass, and plastics, flexible devices offer several unique advantages, such as simplified fabrication, lower costs, enhanced portability...

5 years ago

11 minutes

SLAS Technology Authors Talk Tech

Automated System for Small-Population Single-Particle Processing Enabled by Exclusive Liquid Repellency

Volume 24 Issue 6, December 2019 Dave Pechter discusses with Chao Li the article, "Automated System for Small-Population Single-Particle Processing Enabled by Exclusive Liquid Repellency." Lossless processing and culture of rare cells (e.g., circulating tumor cells, drug-persistent microorganisms) at single-cell level is of great significance in understanding the heterogeneity of carcinogenesis or human pathogenesis caused by microbial infection. Current single-cell isolation techniqu...

5 years ago

10 minutes

SLAS Technology Authors Talk Tech

Special Issue: Engineering Innovations for Fundamental Biology and Translational Medicine

SLAS Technology 24.5 October 2019 Professors at Johns Hopkins University, Claire Hur and Deok-Ho Kim, discuss their special issue, "Engineering Innovations for Fundamental Biology and Translational Medicine." In this special issue of SLAS Technology, the editors showcase reviews and original research reports addressing the accuracy in diagnostic and prognostic tests performed on the patient-derived specimen, an emerging technology demand for personalized medicine. Soojung Claire Hur, Ph.D....

6 years ago

10 minutes

SLAS Technology Authors Talk Tech

Technologies for the Directed Evolution of Cell Therapies

Volume 24 Issue 4, August 2019 UCLA Professor, Dino Di Carlo, discusses his review paper, "Technologies for the Directed Evolution of Cell Therapies." The next generation of therapies is moving beyond the use of small molecules and proteins to using whole cells. Compared with the interactions of small-molecule drugs with biomolecules, which can largely be understood through chemistry, cell therapies act in a chemical and physical world and can actively adapt to that world, amplifying ...

6 years ago

11 minutes

SLAS Technology Authors Talk Tech

Special Collection: Advances in 3D and Organoid Cell Culture

SLAS Technology 24.1 February 2019 Guest Editor Richard M. Eglen of Corning Life Sciences (Tewksbury, MA, USA) talks about a new collection of reviews and original research reports that illustrate how the combination of human iPS cells and 3D cell culture technology provide powerful new approaches to the development of novel and more effective therapies. Free access to the published collection is sponsored by Corning Life Sciences.

6 years ago

13 minutes

SLAS Technology Authors Talk Tech

Improved Fluorescence Methods for High-Throughput Protein Formulation Screening

SLAS Technology 23.6 December 2018 University of Kansas researchers Yangjie Wei and Nicholas Larson talk about how they used a steady-state/lifetime fluorescence-based, high-throughput platform to develop a general workflow for direct formulation optimization under analytically challenging but commercially relevant conditions.

6 years ago

6 minutes

SLAS Technology Authors Talk Tech

Special Issue: The Internet of Things (IoT) in the Life Sciences Laboratory

SLAS Technology 23.5 October 2018 Guest Editor James M. Gill, II, Ph.D., of BFL Consulting (Madison, CT) talks about how the October 2018 issue of SLAS Technology showcases life sciences researchers who are pioneering the use of powerful yet accessible and low-cost IoT technologies in their laboratories. Ten articles illustrate how IoT is being used to optimize factors such as throughput, cost, uptime and result quality.

7 years ago

7 minutes

SLAS Technology Authors Talk Tech

Continuous and Quantitative Purification of T-Cell Subsets for Cell Therapy Manufacturing Using Magnetic Ratcheting Cytometry

SLAS Technology 23.4 August 2018 UCLA’s Coleman Murray, Ph.D., talks about his contribution to the August 2018 special issue of SLAS Technology on Enabling Technology in Cell-Based Therapies by guest editor Chris Puleo and his associates at General Electric Global Research. Murray’s article illustrates an important example of how new technologies are changing automation and processing in cell therapy manufacturing.

7 years ago

7 minutes