Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known ...
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Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known ...
Special Issue: Advances in Cellular Target Engagement and Target Deconvolution
SLAS Discovery Author Insights
21 minutes
5 years ago
Special Issue: Advances in Cellular Target Engagement and Target Deconvolution
Volume 25 Issue 2, February 2020Podcast Editor Rob Howes discusses the SLAS Discovery 2020 February Special Issue with Martin Main and Andrew Zhang. To read their editorial, click here. In this Special Issue of SLAS Discovery, the authors explore multiple aspects of cellular target engagement; from direct measurement of compound-target interaction using BRET technologies, through measurement of compound induced changes in protein stability and localisation, to in vivo drug distribution and ta...
SLAS Discovery Author Insights
Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known ...