Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known ...
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Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known ...
Behind the Article: A Perspective on the Discovery of Enzyme Activators
SLAS Discovery Author Insights
9 minutes
2 years ago
Behind the Article: A Perspective on the Discovery of Enzyme Activators
Welcome to the SLAS Discovery Author Insights podcast! Today we are joined by Antonia Turberville and Geoffrey A. Holdgate to discuss their recent perspective article titled "A perspective on the discovery of enzyme activators". This article sheds light on the largely under-explored area of enzyme activation in drug discovery.Despite the successful application of enzyme activators in various therapeutic interventions, the field remains under-represented and poorly exploited. Antonia and Geoff...
SLAS Discovery Author Insights
Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known ...
