Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

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Primary Care Update

Mark Ebell

193 episodes

6 days ago

Four healthily skeptical primary care physicians discuss the latest in primary care medicine. Join Essential Evidence Editor Mark Ebell MD, Rush University's Kate Rowland MD, MSU Professor of Medicine Gary Ferenchick MD, and POEMs co-founder Henry Barry MD, MS for this fast-paced weekly update on evidence-based primary care.

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Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

Primary Care Update

29 minutes 55 seconds

2 weeks ago

Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

This week, Gary, Kate, Mark and Henry discuss the optimal duration of anticoagulation after a provoked DVT, using low doses of mirtazapine or amitriptyline in adults with insomnia, whether a lower dose of semaglutide is still effective for weight loss, and adding aspirin for patients with coronary heart disease, a stent and who are also on a DOAC for another indication.

Links:

NICE Barrett Esophagus guideline: https://pubmed.ncbi.nlm.nih.gov/38553042/

Essential Evidence Plus: www.essentialevidenceplus.com

Duration of anticoagulation: https://pubmed.ncbi.nlm.nih.gov/40888734/

Mirtazapine or amitriptyline for insomnia: ttps://pubmed.ncbi.nlm.nih.gov/39814428/

Lower dose semaglutide for obesity: https://pubmed.ncbi.nlm.nih.gov/40934115/

Adding aspirin: N Engl J Med . 2025 Oct 23;393(16):1578-1588https://pubmed.ncbi.nlm.nih.gov/40888725/