Three years ago British journalist Dom Phillips and Brazilian indigenous defender Bruno Pereira vanished while on a reporting trip near Brazil’s remote Javari valley. The Guardian’s Latin America correspondent Tom Phillips investigates what happened in the first episode of a new six-part investigative podcast series. Find episode 2 – and all future episodes – by searching for “Missing in the Amazon”

As Elon Musk and Donald Trump continue to sling accusations at each other on their social media platforms, Jonathan Freedland speaks to Susan Glasser of the New Yorker about what caused it to all fall apart

Last week Robert F Kennedy Jr, Donald Trump’s health chief and a longtime vaccine sceptic, presented a report on children’s health by the Make America Healthy Again (Maha) commission. The study singled out the negative impact of vaccines, ultra-processed foods, environmental chemicals, lack of exercise and “over-medicalisation”. This week, Jonathan Freedland speaks to Jessica Glenza about the long-term implications of the Maha movement’s influence on US policy

As scepticism grows over Joe Biden’s mental and physical health during his presidency, Jonathan Freedland speaks to Bakari Sellers, a political commentator and former Democratic state lawmaker, about what the party needs to do to regain trust after the fallout from the 2024 election

From a trip to the Middle East to talks between Russia and Ukraine, it’s a busy week for Donald Trump and US foreign policy. Jonathan Freedland speaks to the Guardian’s global affairs correspondent, Andrew Roth, about the big players behind the US president’s deals and decisions on the world stage

Jonathan Freedland and the senior Washington editor of Semafor, Elana Schor, discuss what the US president is choosing to make a priority, and what he’s neglecting in return

To mark his 100th day in office, Donald Trump sat down with the Time journalist Eric Cortellessa, who here speaks to Jonathan Freedland about what he learned from his hour-long interview with the US president

The US justice department says it did not fire a former pardon attorney, Liz Oyer, after she refused to recommend reinstating Mel Gibson’s gun rights. But Oyer tells Jonathan Freedland a different story, one she believes points to a wider crackdown by the Trump administration on the rule of law in America

This week, Harvard University, the oldest and wealthiest in the US, defied Donald Trump a list of demands. The Trump administration responded by freezing $2.2bn in federal funding for the Ivy League school. This week, Jonathan Freedland speaks to the Harvard professor Ryan Enos to consider why the university is pushing back, how far this fight may go and why other universities are watching closely

After doubling down on his promise not to pause his latest tariffs, Donald Trump has announced a 90-day pause for most countries except China. Why did he change his mind? Jonathan Freedland speaks to James Bennet of the Economist about who might have forced the president’s hand, and what could happen next

In a special episode, Jonathan Freedland and Annie Karni of the New York Times look at what seems to be a long-term question for US politics. With Republicans fighting each other in the House and Senate, and Democrats struggling to command the room, is Congress broken? Annie’s new book with Luke Broadwater is called Mad House: How Donald Trump, Maga Mean Girls, a Former Used Car Salesman, a Florida Nepo Baby, and a Man With Rats in His Walls Broke Congress

The Guardian’s Rachel Leingang speaks to Nikki McCann Ramirez, from Rolling Stone magazine, about Donald Trump’s decision to upend US trade policy and reports that Elon Musk could soon be leaving his role as a special government employee Send your questions and feedback to politicsweeklyuk@theguardian.com Help support the Guardian by going to theguardian.com/politcspodus

As Donald Trump and his top officials scrabble to respond to the Signal leak scandal, Jonathan Freedland and the New Yorker’s Susan Glasser discuss the fallout of this security breach, and why the US president is attacking the media instead of the people who let a journalist read potentially classified material

This week a Democratic lawmaker became the first to officially call for the senate minority leader, Chuck Schumer, to step down. The veteran Democrat angered many in his party last week when he backed a Republican funding bill that averted a government shutdown. But this is just one example of a party in crisis trying to oppose the Trump administration, with very little power in Congress.This week, we hear from representatives Jamie Raskin of Maryland, Ro Khanna of California, Julie Johnson of Texas, and Maxwell Frost of Florida on how they would like their party to move forward. Plus, Jonathan Freedland asks the senior Democratic strategist Waleed Shahid what the party’s strategy should beSend your questions and feedback to politicsweeklyamerica@theguardian.comHelp support the Guardian. Go to theguardian.com/politcspodus

This week, Jonathan Freedland speaks to Heather Boushey, an economist and former adviser to Joe Biden, about what Donald Trump’s long game is with his trade war, and how voters will view his handling of the economy should there be a ‘Trumpcession’Send your questions and feedback to politicsweeklyamerica@theguardian.comHelp support the Guardian by going to theguardian.com/politcspodusListen to Science Weekly’s episode on the chaos Trump has unleashed on science

This week, Donald Trump picked fights with Canada, Mexico, Ukraine, US veterans and every Democrat sitting in Congress for his State of the Union address. Chris Michael and Joan E Greve discuss why the US president is turning up the heat on longtime allies, whether Democrats are responding successfully and, in the end, who loses out if Trump’s tactics fail?Send your questions and feedback to politicsweeklyamerica@theguardian.comHelp support the Guardian by going to theguardian.com/politcspodus

This week, Donald Trump continued to dominate the world stage, welcoming a procession of global leaders to Washington, including Keir Starmer. But while the ‘special relationship’ is front and centre in the UK, attention in the US is very much elsewhere. As the president goes full steam ahead with his domestic agenda, there are warning signs for Trump in the polls. So, could he be in trouble at home? And how could the Democrats take advantage? Jonathan Freedland speaks to Stanley Greenberg, the bestselling author, Democratic pollster and political strategist who played a crucial role in the elections of Bill Clinton and Tony Blair

In a matter of days, Donald Trump completed the most radical shift in US foreign policy in decades, bringing Putin back into the fold while sidelining Europe. He claims to have brought the end of the war in Ukraine in sight, but with Volodymyr Zelenskyy and the rest of Europe excluded from the US-Russia talks, are we really any closer to peace? And, at what price?Jonathan Freedland speaks to veteran US diplomat Kurt Volker, who served as Trump’s special representative for Ukraine during his first term, and the Guardian’s US live news editor Chris Michael Send your questions and feedback to politicsweeklyamerica@theguardian.com Help support the Guardian by going to theguardian.com/politcspodus

On the first day of his second term in office, Donald Trump suggested he wanted the US to ‘expand’ its territory. Few thought he could actually mean taking Canada and making it the 51st state. But could he actually do that? Jonathan Freedland speaks to the reporter Leyland Cecco in Toronto about the possibility of the two North American allies merging, what Canadians think about it, and why this existential threat has had an impact on Canadian national politics Send your questions and feedback to politicsweeklyamerica@theguardian.com Help support the Guardian by going to theguardian.com/politcspodus

Between Donald Trump’s suggestion that the US could take control of the Gaza Strip, forcibly removing Palestinians from their homes, and Elon Musk’s continued efforts to dismantle the US federal government, the critics are lining up. The Democrat senator Andy Kim is one of them. But what can he, his party, or anybody else do to stop the president and his non-elected billionaire pal? He speaks to Jonathan Freedland