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On The Pen With Dave Knapp
Dave Knapp Man On The Mounjaro, Bleav
136 episodes
5 days ago
Dave Knapp brings you your weekly dose of everything in the news about incretin mimetic, diabetes and obesity therapies, like Zepbound and Mounjaro, Ozempic and Wegovy, and even investigational treatments like CagriSema and Retatrutide!
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Medicine
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Business News,
Health & Fitness
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All content for On The Pen With Dave Knapp is the property of Dave Knapp Man On The Mounjaro, Bleav and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Dave Knapp brings you your weekly dose of everything in the news about incretin mimetic, diabetes and obesity therapies, like Zepbound and Mounjaro, Ozempic and Wegovy, and even investigational treatments like CagriSema and Retatrutide!
Show more...
Medicine
News,
Business News,
Health & Fitness
Episodes (20/136)
On The Pen With Dave Knapp
GLP-1 Microdosing For Weight Loss: Noom CEO Explains Their New Program
GLP-1 microdosing is one of the hottest and most controversial topics in obesity medicine right now. Can lowering your dose instead of quitting completely help you keep the weight off? In this exclusive interview, Noom CEO Geoff Cook responds to questions about microdosing, GLP-1 off-ramping, and how Noom supports patients using medications like Mounjaro, Zepbound, Wegovy, and Ozempic.
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5 days ago
42 minutes 22 seconds

On The Pen With Dave Knapp
Eli Lilly Earnings Call Recap: Stock Tanks on Weight Loss Pill Miss
Zepbound now leads two-thirds of the U.S. obesity market—and that’s just the beginning. In this video, we break down the biggest headlines from Eli Lilly’s latest earnings call, including: ✅ Over 1 million Zepbound vials prescribed in Q2 ✅ New Phase 3 tirzepatide trial for type 1 diabetes ✅ 39% reduction in all-cause mortality (MACE-3) ✅ Orforglipron data and pricing strategy revealed ✅ Retatrutide and the future of complex obesity care ✅ Employer coverage shifts and LillyDirect updates ✅ The real reason behind Lilly’s compounding crackdown ✅ How Canadian generics might replace U.S. compounders 🎯 Whether you’re on GLP-1 meds or just trying to get answers in a system that keeps moving the goalposts, this episode is for you.
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1 week ago
59 minutes 23 seconds

On The Pen With Dave Knapp
Novo Nordisk Blames Compound Semaglutide on Slower Sales
Novo Nordisk Q2 2025 Earnings: What It Means for GLP-1s, Compounded Semaglutide, Amycretin & Obesity Treatment In this breakdown of Novo Nordisk’s Q2 2025 earnings call, I cover the biggest takeaways for anyone using or considering GLP-1 medications like Ozempic, Wegovy, Rybelsus, and semaglutide for obesity, type 2 diabetes, and related comorbidities.
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1 week ago
24 minutes 38 seconds

On The Pen With Dave Knapp
No Compounded Retatrutide Says the FDA + Tons of GLP-1 News
This week Dave covers all the obesity medicine news that will empower you to have more informed conversations with your doctor. This week's topics include: FDA Statement on Non Branded GLP-1 Meds Lilly is Getting to Root Cause Obesity Medicine, Beyond Tirzepatide A Landmark Study for Mounjaro Preview of Upcoming Earnings Calls
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1 week ago
41 minutes 14 seconds

On The Pen With Dave Knapp
LEAKED TRUMP DOCUMENT: Medicare to Cover Zepbound and Wegovy for Obesity
Breaking News Today from the Trump administration on the cost of GLP-1
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2 weeks ago
26 minutes 46 seconds

On The Pen With Dave Knapp
Retatrutide Drops are Crazy // OTP TWD 7.29.25
In this week's epidsode of The Weekly Dose Podcast, Dave covers some whacky versions of Retatrutide that are popping up from interesting sources. He also covers all the big stories in GLP-1 from this past week.
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2 weeks ago
33 minutes 17 seconds

On The Pen With Dave Knapp
Compound GLP-1 Injections : You Won't Believe What The Obesity Society is Saying
This week Dave covers: The Obesity Society congressional hearing slamming compounded #tirzepatide and #semaglutide A study that may show GLP-1 reduces breast cancer tumors: A study that may show GLP-1 increases size of rare neuroenocrine tumors:
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3 weeks ago
24 minutes 4 seconds

On The Pen With Dave Knapp
Connecticut Making Ozempic!? Meet The Mastermind
In this episode of On The Pen: Faces of the Fight, I sit down with Connecticut State Senator Matt Lesser, the lawmaker behind one of the boldest health policy moves in recent memory. We talk about Connecticut’s newly passed bipartisan prescription drug affordability bill and the groundbreaking provision buried inside it — a plan to petition the federal government for permission to manufacture their own GLP-1 medications like Ozempic. Senator Lesser explains how this little-known federal law could allow Connecticut to override pharmaceutical patents in the public interest, why the state is spending over 150 million dollars a year on GLP-1s, and how this approach could bring drug prices down not just in Connecticut, but potentially nationwide. We also dig into timelines, political strategy, and the real-world implications of a state trying to break Big Pharma’s pricing model. If you care about access, affordability, and the future of obesity treatment in America, this is one you don’t want to miss.
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1 month ago
26 minutes 22 seconds

On The Pen With Dave Knapp
SHOCKING: How GLP-1 Protects the Heart Beyond Weight Loss // OTP TWD 7.25.25
Get All The Referenced Links: https://linktr.ee/manonthemounjaro
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1 month ago
20 minutes 20 seconds

On The Pen With Dave Knapp
BREAKING: Insurance Approving Mounjaro Over Zepbound!? What is Going On!?
is CVS forcing Zepbound users to Mounjaro?
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1 month ago
17 minutes 34 seconds

On The Pen With Dave Knapp
Behind the Scenes of the Obesity Drug Battle | Obesity Action Coalition President Interview
Interview with Joe Nadglowski, President of the Obesity Action Coalition (OAC) Host: Dave Knapp (On The Pen) In this compelling and wide-ranging conversation, Dave Knapp welcomes Joe Nadglowski to discuss the critical work of the Obesity Action Coalition. Celebrating its 20th anniversary, the OAC remains the only national nonprofit organization focused on representing people living with obesity. Joe shares his personal journey—including trying seven medications—and explains how the OAC emerged to fill a massive void: the absence of patient voices in legislative and medical decision-making. The discussion highlights: The uphill battle for FDA approval of obesity medications and how OAC helped reshape advisory panels to include patients and obesity experts. The Treat and Reduce Obesity Act (TROA): A bipartisan effort to expand Medicare coverage for obesity treatment and counseling, which has now been introduced in eight consecutive Congressional sessions. The systemic failure of insurance companies, which often exclude obesity care, leaving patients to fend for themselves or rely on compounders and even gray-market alternatives. The importance of access: Joe and Dave argue that all innovation is meaningless unless patients can actually get the medications. Compounding: While OAC officially does not endorse compounded medications due to safety concerns, Joe clarifies that he holds no judgment for patients who use them and acknowledges the systemic failures that drive people to do so. The bigger picture: They touch on PBM reform, drug pricing transparency, and whether “Most Favored Nation” drug pricing policies could make branded medications more affordable. Action steps for viewers: Joe invites the community to join OAC for free, get involved in advocacy through their Action Center, and attend the upcoming YWM (Your Weight Matters) Convention in D.C., which includes an advocacy day on Capitol Hill. The conversation blends personal experience, deep policy insight, and a call to collective action.
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1 month ago
35 minutes 23 seconds

On The Pen With Dave Knapp
Unlocking Zepbound Insurance Coverage + More GLP-1 Good News // otp twd 7.1.25
If you are losing Zepbound coverage, you have got to check this podcast out! Plus Dave covers this week's news in obesity medicine!
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1 month ago
33 minutes 37 seconds

On The Pen With Dave Knapp
Lilly Could Lose Their Tirzepatide Patent! Plus ADA Coverage // OTP TWD 06.24.25
Dave covers some big news from the American Diabetes Association 85th Scientific Sessions. Also, some crazy news on how Eli Lilly could lose their patent on #tirzepatide and what that would mean for obesity medicine.
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1 month ago
26 minutes 52 seconds

On The Pen With Dave Knapp
Faces of The Fight: The Jamie Selzler Story
At 650 pounds, GLP-1 injections helped give Jamie His Life Back. Get Our Newsletter and Help us Grow! https://www.obesity.news Support OTP (all our links): https://linktr.ee/manonthemounjaro
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1 month ago
57 minutes 43 seconds

On The Pen With Dave Knapp
Zepbound Vials Drop, Amycretin Surges, FDA Fast Track, and a Dangerous Trend // TWD 6.17.25
Zepbound’s 12.5 and 15 mg vials are finally being released—but there’s a catch that could cost you over $1,000 if you miss it. We also break down Amycretin’s jaw-dropping 24% weight loss data and Novo’s surprising leap straight to Phase 3. Plus, a new FDA program could fast-track future obesity drugs like CagriSema and Retatrutide. And finally, we issue a serious warning about the rise of research-grade cagrilintide being injected at home. This one’s packed. Let’s go.
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2 months ago
29 minutes 32 seconds

On The Pen With Dave Knapp
GLP-1 Access Progress + The Race for Less Frequent Dosing: OTP TWD 6.10.25
https://www.linktr.ee/manonthemounjaro Ozempic rare eye disease update The the race for once monthly dosing Big insurance wins incoming?!
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2 months ago
22 minutes 33 seconds

On The Pen With Dave Knapp
Lilly Makes Bold Move on GLP Dosing / 8x More Ozempic? / Wegovy Use in Teens
DAVE RECAPS THIS WEEK'S NEWS IN OBESITY MEDICINE
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2 months ago
21 minutes 18 seconds

On The Pen With Dave Knapp
Trump Admin Setting Price Targets for Zepbound and Ozempic, Will Pharma Go Along?
Welcome back to On The Pen: The Weekly Dose, your go-to podcast for breaking GLP-1 and obesity medicine news. In this episode, host Dave Knapp (aka Man On The Mounjaro) dives deep into the week’s biggest updates — from the Trump administration’s bold executive order to enforce Most Favored Nation pricing for drugs like Zepbound and Ozempic, to a major ruling against compounded tirzepatide that could reshape access for patients across the country. We unpack Judge Pittman’s ruling against the Outsourcing Facilities Association, what it means for 503B pharmacies, and why telehealth companies are scrambling to pivot to 503A custom dosing. Plus, we break exclusive news on EMR provider Tebra and payment processor Stripe allegedly threatening doctors with a financial blackout for prescribing compounded GLP-1 medications. Also in this episode: big updates on the On The Pen movement — including hitting #1 on Substack in health and wellness, and the launch of our brand new newsroom, built from the ground up to keep fighting for patient access and accountability in obesity medicine. If you care about access to Ozempic, Wegovy, Mounjaro, Zepbound, compounded semaglutide, or tirzepatide... this is the episode you cannot miss.
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3 months ago
29 minutes 47 seconds

On The Pen With Dave Knapp
Zepbound vs. Wegovy, CVS vs. Patients, and the Executive Order That Changes Everything
CVS just dropped Zepbound in favor of Wegovy — despite new SURMOUNT-5 data proving Zepbound is more effective. In this episode of On The Pen, Dave Knapp breaks down the Most Favored Nation Executive Order, the PBM influence behind the CVS decision, and what patients can do before and after the July 1 coverage change. Featuring a sit-down interview with Joe Zucchi, PA-C, who launched the viral petition to reverse this move.
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3 months ago
41 minutes 2 seconds

On The Pen With Dave Knapp
Compound Tirzepatide Lawsuit + PBM Reform Update // OTP TWD 5.6.25
Dave discussed the latest update in the OFA vs FDA compound tirzepatide battle, as well as this weeks news in obesity medicine.
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3 months ago
26 minutes 31 seconds

On The Pen With Dave Knapp
Dave Knapp brings you your weekly dose of everything in the news about incretin mimetic, diabetes and obesity therapies, like Zepbound and Mounjaro, Ozempic and Wegovy, and even investigational treatments like CagriSema and Retatrutide!