What’s cancer got to do with crabs, artist Jackson Pollock, and artificial intelligence? It’s not a riddle; these are some of the things we’ll explore with surgeon Grant Stuart, computer scientist Mateja Jamnik and radiologist Evis Sala. In this episode, we’ll discover how artificial intelligence is making it easier for doctors to diagnose and treat cancer and we’ll share some cancer facts that are both amazing and disturbing. We also learn about the WIRE clinical trial for kidney cancer. WIRE evaluates the effectiveness of giving a short course of drug treatment to patients in the one-month “window of opportunity” between diagnosis and surgery. Patients on the WIRE trial also undergo a suite of new imaging techniques that have been brought together for the first time globally in this clinical trial.

Is antimicrobial resistance (AMR) the greatest threat to human health? In this episode, we discuss how the misuse and overuse of antimicrobials in humans and agriculture have accelerated bacteria, viruses, and other pathogens’ ability to mutate and develop resistance against the treatments designed to curb and control them. We talked with molecular biologist Stephen Baker, virologist Ian Goodfellow and infectious disease epidemiologist Caroline Trotter about the magnitude of the problem and how it is not a problem of the future, but of the now. Along the way, we discuss whether post COVID19, are we in a better position now to deal with the next pandemic? Can we predict when it might happen? And if it does happen, will we deal with it any differently?

What causes dementia? And how do we diagnose and treat it? Is there anything we can do to stop ourselves from developing dementia? These are the crucial questions we’ll be exploring with clinical neuropsychologist Barbara Sahakian, sociologist Richard Milne, and neurologist James Rowe. In this episode, we’ll find out more about what dementia actually is, some surprising factors that increase a person’s risk of developing dementia, and computer games that can actually help detect and diagnose dementia.

COVID-19 has disrupted the lives of everyone, including children and young people, beyond recognition. So much so, that the proportion of children aged six to 16 with probable mental health disorders has increased from one in nine in 2017 to one in six in both 2020 and 2021. In this episode, we talked with Professor of Child and Adolescent Psychiatry, Tamsin Ford, Professor of Health Neuroscience Paul Fletcher and behavioural epidemiologist Dr Esther van Sluijs about growing concern over the recent and widespread deterioration of adolescent mental health and what can be done about it. We cover everything from the prevalence of mental health problems and eating disorders, sedentary behaviour and mentally passive activities, to how mental illness is represented in video games and how video games can be used to engage the public with mental illness in the right way. Along the way, we hear about mental health before and during the Covid-19 pandemic. This episode was produced by Nick Saffell, James Dolan, Naomi Clements-Brod and Annie Thwaite.

What role do our genes play in influencing our body weight and what we like to eat? Why do some people gain weight more easily than others, and is it all down to genes or are there other factors at play? In this episode, we talked with a clinician and scientist Sadaf Farooqi, health psychologist Theresa Marteau, and geographer Thomas Burgoine about the multitude of factors that go into influencing our eating behaviours. Along the way, we hear about the crucial importance of the environment in influencing our eating behaviour, including “zoning” - the effort to keep fast food outlets no more than 400 yards from schools, and learn how our food has become more calorific over the past 20 to 30 years. Our guests discuss how ultimately, communicating information about obesity doesn’t necessarily change our behaviour towards food, as we are much more influenced by our genes and environment than what's inside our heads. This episode was produced by Nick Saffell, James Dolan, Naomi Clements-Brod and Annie Thwaite.

Season 3 is here, and we’re back discussing all things Health! Welcome (or welcome back) to Mind Over Chatter, the Cambridge University Podcast. One series at a time, we break down complex issues into simple questions. In this third series, we’re talking all about Health. We’ll be exploring both physical and mental health, and we’ll discuss causes, treatments and preventions for issues like dementia, cancer, infectious diseases and obesity. We’re going to be talking to interesting people from all over the University of Cambridge, including geographers, surgeons, computer scientists, molecular microbiologists, sociologists… and many more! We’ll cover everything from infectious diseases and how we can use vaccines to prevent them, to Tinder for bacteria; from artificial intelligence helping us tackle cancer, to Grandpa JPEG and all the Little Pixels, from adolescent mental health and eating disorders to Senua, the Pict warrior hero of the blockbuster video game Hellblade; from obesity and the gene-environment debate, to how a room full of Twixes is like a room full of Borg (resistance is futile); and from dementia and new approaches to its diagnosis and treatment, to “Tau Tangles” - the new brand of Greek noodle.

Our reproductive capabilities are changing in exciting ways, altering our fundamental understanding of fertility, reproduction, and even parenthood. In this episode, we asked our guests what the consequences of novel reproductive technologies are likely to be, and how they will impact the future of human reproduction. Alice Reid told us about how reproduction has changed over the last 200 years and the likely demographic impact of assisted reproduction, while Lucy Van de Wiel introduced the important ways in which reproductive technologies must be considered in the context of wide social and political issues. Thorsten Boroviak shared his exciting and cutting-edge research on developing new reproductive technologies. We cover topics ranging from egg-freezing, so-called ‘three-parent-babies, and the importance of studying the embryonic development of primates. This episode was produced by Nick Saffell, James Dolan and Naomi Clements-Brod. Annie Thwaite and Charlotte Zemmel provide crucial research and production support for Series 2.

Artificial Intelligence can be found in every aspect of our lives. From A-level grade predicting algorithms to Netflix recommendations, AI is set to change the choices we make and how our personal information will be used. In this episode, we explore the future of AI - its potential benefits and harms - with our three guests. Beth Singler told us about the different cultural consequences of AI, and how the way we think about the future of AI reflects more about society today than the future itself. John Zerilli shared his views on the consequences of AI for democratic decision-making, and Richard Watson urged us to conceive of the future of AI in terms of ‘scenario planning’, rather than predicting the future directly. We cover topics ranging from how to make AI ‘ethical’, how the media representation of AI can colour the public’s perception of what the real issues are, and the importance of an international AI regulatory system. This episode was produced by Nick Saffell, James Dolan and Naomi Clements-Brod. Annie Thwaite and Charlotte Zemmel provide crucial research and production support for Series 2.

Our society is more unequal than ever, as the top 1% control over 44% of the world’s wealth while 689 million people are living on less than $1.90 per day. In this episode, we asked our guests what the future of fairness, justice, and equality should look like, and how their research can help to bring about a fairer society. Alexa Hagerty and Natalie Jones shared how injustice can be thought of as an existential risk to humanity, while Esra Ozyurek introduced us to the importance of understanding that different people have different needs, making equality insufficient to bring about justice. We cover topics ranging from distributive justice, the virtues and vices of empathy, and the role AI will play in shaping equality in the years to come. This episode was produced by Nick Saffell, James Dolan and Naomi Clements-Brod. Annie Thwaite and Charlotte Zemmel provide crucial research and production support for Series 2.

Our wellbeing is essential to our overall quality of life. But what is wellbeing? Why is it so hard to pin down? How is it different to mental health, and what can we do to understand, measure and improve it? We talked with psychologist and neuroscientist Dr Amy Orben, psychiatrist Dr Tamsin Ford, and welfare economist Dr Mark Fabian to try and get to grips with wellbeing. In doing so, we learnt about the negative (and positive!) effects of the pandemic, how wellbeing differs for children and adults, and the influence of ever-evolving technology on our wellbeing.

We all have theories about what the future might look like. But what did the future look like in the past? And how have the advent of new technologies altered how people viewed the future? We talked with curator of modern sciences and historian of Victorian science Dr Joshua Nall, professor of Digital Humanities and director of Cambridge Digital Humanities Professor Caroline Bassett, and Junior Research Fellow in the history of artificial intelligence Dr Jonnie Penn in our attempt to understand how the future was thought of in the past. Along the way we discussed utopias and dystopias, the long history of science fiction, and how the future might come back to haunt us!

Hello and welcome back to Mind Over Chatter! This second series is all about the future - and in this first episode we’re going to be considering what the future even is… Have you ever wondered how time works? It turns out, the answer is a lot more complicated than we thought. Join our wondering and wonderful conversation with philosopher of science Matt Farr, professor of psychology Nicky Clayton, and professor of linguistics and philosophy, Kasia Jaszczolt. We’ll be talking about everything from physics to linguistics… and from broken eggs to Einstein’s theory of relativity.

In this last episode of the series, we’ll be exploring how stories work for and against climate change. We cover a lot of ground: from hippos and polar bears to how many times ‘sex’ and ‘tea’ were mentioned on TV between 2017 and 2018… so what’s all of this got to do with sustainability and climate change? Join us to find out! Our storytelling experts this time are Richard Staley (lecturer in the history and philosophy of science, Sarah Dillon (author, researcher and broadcaster) and Martin Rees (cosmologist, astrophysicist, and Astronomer Royal).

How and what we eat, and where our food comes from, these everyday choices that we often think very little about, have become increasingly relevant to climate change. With a global population projected to reach 10 billion by 2050, it is not unreasonable to ask: how are we going to feed all these people... and without causing more damage? In this episode we’ll cover everything from how climate change will affect the way we grow and eat food, to the pros and cons of ‘non-poo’ fertiliser. Sound appetising? Giles Oldroyd, professor of plant science at the new Cambridge Crop Science Centre, Helen Anne Curry, lecturer in the history of modern science and technology, and developmental economist, Shailaja Fennell, helped us connect the dots between food and climate change. They discuss how we ensure people around the world will still have food to eat as the climate becomes more unpredictable.

The future is becoming harder to predict thanks to climate change and a global pandemic. But a large part of what the future will look like is in our own hands. The biggest challenge to creating a better future may be political rather than scientific or technological. In this episode, Diane Coyle, professor of public policy, Laura Diaz Anadon, professor of climate change policy, and architectural engineer, Ruchi Choudhary, join us to talk about how we can build a future that might not be anything like the past. We cover topics like innovation, GDP, and how the uncertainty created by climate change can help propel policy and economic decisions. Plus, we look at some of the benefits that come with building a greener future together.

Last episode, we talked about how we got to where we are now with climate change, but do we even know what’s going on with climate change right now? In this episode we’ll talk about what tipping points we’re approaching, how and why we’re still struggling to gain momentum toward action on climate change, and what difference it would make if carbon dioxide was a brown smelly substance. To figure all of this out, we talked to a mathematician, Emily Shuckburgh, an engineer Hugh Hunt and a psychologist, Sander van der Linden. Along the way, we discuss solutions like geoengineering, creating a fake news ‘vaccine’ and opportunities for businesses to be more transparent about how their activities contribute to climate change.

Climate change is likely to affect almost every area of our lives… but how did we get to this point? When and why did we first take notice of climate change? And why has climate change evaded our collective attention and action for so long? We talked with professor of human geography, Mike Hulme, science historian and journalist Dr Sarah Dry and environmental economist Dr Matthew Agarwala to try to figure all of this out. Along the way, we discovered new ways of thinking about climate change, from a tragic story where the issue is constantly caught between opposing forces, to more hopefully thinking of it as a source of generative change and innovation.