Join us for an in-depth discussion on Acute-on-Chronic Liver Failure (ACLF) with Dr. Christina Lindenmeyer, board-certified transplant hepatologist at the Cleveland Clinic and founder of their groundbreaking Medical Intensive Liver Unit (MILU).
Dr. Lindenmeyer, who serves as Vice Chair of the AASLD ACLF Special Interest Group, breaks down the essential definitions and diagnostic criteria of ACLF, explores evidence-based management strategies, and shares insights from her extensive research in liver failure and transplantation.
We are excited to announce we have two new fellow hosts, Vlad Fomin and Dilara Hatipoglu! They are so excited to spend the year with you all learning about the liver. Listen to the end as we debut a brand new lightning round!
In Liver we trust.
On this episode of Liver Talks, Gideon Hirschfield, the Lily and Terry Horner Chair in Autoimmune Liver Disease Research and Professor at the University of Toronto, comes on to talk about the latest advances in primary biliary cholangitis.
Also, we bid Patrick Lee adieu and set the stage for new fellow leads!
Hosts:
Patrick Lee
Adam Winters
Alex Vogel
Guests:
Gideon Hirschfield
Edited by:
Taylor Gouterman
Enjoy a fantastic talk with the master of portal hypertension, Guadalupe Garcia-Tsao. Perfect for listening whilst in transit to or from San Diego for AASLD!
We are looking for interested trainees to take the reins of fellow lead for Liver Talks next academic year (2025-2026). Feel free to e-mail liverfellownetwork@gmail.com if you are interested in learning more.
Hosts:
Patrick Lee
Adam Winters
Alex Vogel @AlexSVogel
Guests: Guadalupe Garcia-Tsao @ggarciatsao Edited by: Taylor Gouterman
Music Credits: “Tropkicks”, Broke for Free “Something Elated”, Broke for Free “Take Me Higher”, Jahzzar “RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.http://brokeforfree.com/https://jahzzar.bandcamp.com/https://blankkytt.bandcamp.com
Big time guest alert!
Dr. Michael Lucey joins us to talk about all things ALD - including early LT and whether or not he uses steroids or steroids + NAC for severe AH. Which is it? You'll have to listen!
Hosts:
Patrick Lee
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Michael Lucey
Robert Wilechansky @WilechanskyMD
Edited by:
Taylor Gouterman
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com
After a respite, Liver Talks is back with a very special guest. We talk to Norah Terrault, Chief of Gastroenterology and Hepatology at Keck Medical Center of USC, about her career, the MASLD nomenclature change, and her work with AASLD. Then, Rob Wilechansky is back to walk us through the latest and greatest published in Hepatology.
Hosts:
Patrick Lee
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Norah Terrault @norahterrault
Robert Wilechansky @WilechanskyMD
Edited by:
Taylor Gouterman
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
Adam and Alex start by introducing the new fellow lead for Liver Talks, Patrick Lee - a GI fellow at USC. The bulk of the episode is spent discussing a recent paper Adam published about finding your first hepatology job after fellowship. They discuss when and how to apply, what to prioritize, and negotiation tactics. Finally, Rob Wilechansky drops by to discuss a PBC clinical trial recently published in Hepatology.
Jobs Paper: https://pubmed.ncbi.nlm.nih.gov/37309214/
PBC Trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344437/
Hosts:
Patrick Lee
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Robert Wilechansky @WilechanskyMD
Edited by:
Taylor Gouterman
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
On this episode of Liver Talks, Alex and Adam are joined by Amit Singal, HCC expert and Chief of Hepatology at UT Southwestern, for a fascinating conversation about the latest and greatest in HCC.
Then, a new segment is born featuring Rob Wilechansky, a transplant hepatology fellow at MGH and Hepatology's editorial fellow, in which they discuss an exciting new article from a recent issue of the journal.
AASLD HCC Guideline: https://journals.lww.com/hep/fulltext/9900/aasld_practice_guidance_on_prevention,_diagnosis,.441.aspx
Tropifexor plus cenicriviroc combination versus monotherapy in non-alcoholic steatohepatitis: Results from the Phase 2b TANDEM study:
https://pubmed.ncbi.nlm.nih.gov/37162151/
Hosts
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Amit Singal @docamitgs
Robert Wilechansky @WilechanskyMD
Edited by:
Taylor Gouterman
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
Alex and Adam are thrilled to host Liver Talks' first time return guest, Dr. Patty Pringle Bloom from the University of Michigan, to talk all about the microbiome and its relationship to liver disease, the International Society for Hepatic Encephalopathy and Nitrogen Metabolism, "lunatic asylums" in Germany and much more!
ISHEN: https://www.ishen.org/
Dr. Bloom's work (a curated selection):
FMT in HE: https://pubmed.ncbi.nlm.nih.gov/35384391/
Post-transplant ascites: https://pubmed.ncbi.nlm.nih.gov/37219847/
Hosts
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
Patty Pringle Bloom @BloomPringle
Edited by:
Taylor Gouterman
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
There are new NASH Guidelines and we're gonna talk about them. Who better to chat with than lead author Dr. Mary Rinella? Probably nobody! But first, the precarities of being an NY Jets fan (sorry) and a heads up about the Liver Meeting abstract deadline.
AASLD NASH Guidelines:
https://journals.lww.com/hep/Fulltext/2023/05000/AASLD_Practice_Guidance_on_the_clinical_assessment.31.aspx
Hosts
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Mary Rinella @marurinella
Edited by:
Taylor Gouterman
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
On this episode of Liver Talks, Adam and Alex welcome their very good friend Dr. Ani Kardashian from the Keck School of Medicine at USC's Division of Gastroenterology and Liver Disease (3:40). She discusses her work focusing on the effect of food insecurity in patients with chronic liver disease, as well as her interest in disparities research. It's a fascinating conversation that has profound implications on clinical practice.
The episode ends with a review of some simple screening tools to help identify patients at risk of food insecurity (41:24)
Work Referenced in the Episode
Dr. Kardashian's work on food insecurity
https://pubmed.ncbi.nlm.nih.gov/36173037/
https://pubmed.ncbi.nlm.nih.gov/34958747/
Dr. Kardashian's encompassing review on disparities in liver disease
https://pubmed.ncbi.nlm.nih.gov/35993341/
Hosts
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Ani Kardashian @AniKardashianMD
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
Adam and Alex catch up with outgoing AASLD president Dr. Laurie DeLeve just prior to the very peaceful transition of power (5:03). They discuss her initiatives for the society over the past year, her interest in mentorship, and if a shared language can be found between basic scientists and clinicians. Plus a new and exciting answer for favorite liver cell!
Our hosts wrap the episode celebrating Alex passing his GI boards and review their respective study strategies (33:50).
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Laurie DeLeve
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
We are joined by Dr. Patty Pringle Bloom and Dr. Parita Patel for a very, very special (and fun) episode of Liver Talks. We talk about the first job search timeline, contracts, lawyers, asking for protected time, getting the tea on the prospective work place--all from the perspective of a clinician, clinician-educator and clinician-researcher. We laughed, we tried to keep Alex--currently undergoing the job search process--from crying and we talked about Love is Blind.
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guests:
Patty Pringle Bloom @bloompringle
Parita Patel @ParitaPatelMD
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
In this episode, Alex and Adam talk with Dr. Sonali Paul of the University of Chicago about the challenges and disparities faced by LGBTQI+ patients and providers. They delve into the dearth of training that surrounds caring for this population, why GI in particular may be missing the mark, and interventions and initiatives that are available to trainees seeking to combat these issues.
Articles by Dr. Paul:
Join the LFN Workroom: https://liverfellow.org/post/the-workroom
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
Sonali Paul @spaulliver
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
On this episode of Liver Talks, Alex and Adam are joined by Dr. Nadim Mahmud of the University of Pennsylvania to discuss his training and career, surgical risk stratification in cirrhosis--notably the creation of his group's VOCAL-Penn score--and tips for getting involved in Big Data.
VOCAL-Penn Instrument: https://www.vocalpennscore.com/
Risk Prediction Models for Post-Operative Mortality in Patients With Cirrhosis: https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep.31558
External Validation of VOCAL-Penn: https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/lt.26060
Join the LFN Workroom: https://liverfellow.org/post/the-workroom
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
Nadim Mahmud @nadimmahmud
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
They made a podcast!
Adam and Alex start by discussing the new LFN initiative: the Workroom--an online community for trainees in GI and hepatology. Then, they welcome in W. Ray Kim, Chief of the Division of Gastroenterology and Hepatology at Stanford University, to discuss his group's latest permutation of the MELD formula, updated for the modern era. Dr. Kim talks about his personal connection with liver disease, important nuance inherent to the new formula, and where MELD may fall short--both currently and in the future. It's a fascinating conversation to start our third year or, sure Alex, season.
Join the Workroom: https://liverfellow.org/post/the-workroom
MELD 3.0 Paper: https://www.gastrojournal.org/article/S0016-5085(21)03469-7/fulltext
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
W. Ray Kim @WRayKimMD
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
With the Liver Meeting rapidly approaching, Adam and Alex talk with current AASLD president Dr. Raymond Chung about his career path, advice for trainees, his most anticipated sessions and much, much more (2:10-50:00). To wrap up, Adam plugs the new transplant hepatology application process starting this coming later this year and the Liver Meeting session dedicated to it, while Alex discusses his poster presentation. (50:30-55:00).
Liver Meeting session for prospective trainees:
Sunday, November 14th 9:00-9:45am
The Liver Meeting Digital Experience
Alex's Poster: Spironolactone, but not furosemide, is associated with the development of hyponatremia in patients with cirrhosis and ascites: is the 100:40 ratio truly optimal? #2016
Feedback? Want to suggest a topic or a guest? E-mail us @ liverfellownetwork@gmail.com or tweet tweet us @Liver_Talks.
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
Raymond Chung @raychungmd
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
Adam and Alex welcome in Dr. Adam Mikolajczyk to discuss his advice for those applying to GI or hepatology fellowships, his recent paper on mandating hepatology education for internal medicine residents and the implications for the hepatology work-force and a career in medical education (4:00-30:00). After, they go over another Alex Vogel original publication about endoscopy "love languages" and talk about their own, personal love languages. (31-43:37)
Dr. Mikolajczyk's paper on mandating hepatology education: https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep4.1792
Alex's love languages paper: https://link.springer.com/article/10.1007/s10620-021-07207-8
Feedback? Want to suggest a topic or a guest? E-mail us @ liverfellownetwork@gmail.com or tweet tweet us @LiverFellow.
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
Adam Mikolajczyk @AdamMikMD
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
Adam and Alex have a chat about life changes (0:04-3:00) before welcoming in Dr. Elliot Tapper for a far-reaching conversation, touching upon mentorship and "menteering", how to say NO as a trainee and, naturally, Bravo reality TV (3:04-36:19). Then, Adam teases a new and welcome change to the transplant hepatology fellowship application process. Finally, Alex discusses his new publication in Liver Transplantation studying the impact of early liver transplant for alcoholic hepatitis on cost and healthcare utilization (36:30-47:00).
Dr. Tapper's "menteering" paper: https://www.gastrojournal.org/article/S0016-5085(17)30228-7/fulltext
Alex's paper on the healthcare utilization and costs for transplantation in ALD: https://pubmed.ncbi.nlm.nih.gov/34133847/
Feedback? Want to suggest a topic or a guest? E-mail us @ liverfellownetwork@gmail.com or tweet tweet us @LiverFellow.
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
Elliot Tapper @ebtapper
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
Dr. David Goldberg from the University of Miami joins the podcast to discuss organ procurement and allocation, how his research has influenced public policy, and much more. [1:15-31:15] Then, Adam and Alex plug a few things they've read over the past month and how they intersect with current events. [32:00-39:58]
The Death of Hahnemann Hospital: https://www.newyorker.com/magazine/2021/06/07/the-death-of-hahnemann-hospital
The Heartbeat of Wounded Knee: https://www.penguinrandomhouse.com/books/316457/the-heartbeat-of-wounded-knee-by-david-treuer/
Feedback? Want to suggest a topic or a guest? E-mail us @ liverfellownetwork@gmail.com or tweet tweet us @LiverFellow.
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Guest:
David Goldberg @DrLiver
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
Adam and Alex talk with Dr. Anjana Pillai from the University of Chicago about her early career (tip: the line at Starbucks may be more fruitful than LinkedIn), liver cancer and starting the HCC-TAG conference (https://www.hcc-tag.org) [1:54-38:16]. Then they discuss the recent study on early-career burnout from Hepatology Communications from this past January [39:44-48:43].
National Early Career Transplant Hepatologist Survey: Compensation, Burnout, and Job Satisfaction
https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep4.1666
Feedback? Want to suggest a topic or a guest? E-mail us @ liverfellownetwork@gmail.com or tweet tweet us @LiverFellow.
National Early Career Transplant Hepatologist Survey: Compensation, Burnout, and Job Satisfaction
https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep4.1666
Hosts:
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel
Music Credits:
“Tropkicks”, Broke for Free
“Something Elated”, Broke for Free
“Take Me Higher”, Jahzzar
“RSPN,” Blank & Kytt
All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com/
COI: Alex does occasional paid consulting work for Centaur Labs, but today’s shout out of the company is unpaid and mostly to support his wife