Life Sciences 360

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Life Sciences 360

Harsh Thakkar

84 episodes

1 month ago

Why Most Healthcare Brands Fail (And How to Fix It) In this episode, Holley Miller, Founder and President of Grey Matter Marketing, reveals why most medtech and life sciences companies fail to connect with their audience—and how to fix that with brand clarity and strategic storytelling. You’ll learn how marketing in regulated industries is evolving, why flashy tactics often fall flat, and how brand equity is built through consistency, credibility, and emotional connection. Holley also share...

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Why Most Healthcare Brands Fail (And How to Fix It) In this episode, Holley Miller, Founder and President of Grey Matter Marketing, reveals why most medtech and life sciences companies fail to connect with their audience—and how to fix that with brand clarity and strategic storytelling. You’ll learn how marketing in regulated industries is evolving, why flashy tactics often fall flat, and how brand equity is built through consistency, credibility, and emotional connection. Holley also share...

Show more...

Episodes (20/84)

Life Sciences 360

Why Most Healthcare Brands Fail (And How to Fix It)

Why Most Healthcare Brands Fail (And How to Fix It) In this episode, Holley Miller, Founder and President of Grey Matter Marketing, reveals why most medtech and life sciences companies fail to connect with their audience—and how to fix that with brand clarity and strategic storytelling. You’ll learn how marketing in regulated industries is evolving, why flashy tactics often fall flat, and how brand equity is built through consistency, credibility, and emotional connection. Holley also share...

4 weeks ago

50 minutes

Life Sciences 360

4.5 Billion Molecules, One Mission: Cure the ‘Undruggable’ Diseases

Solving the “Undruggable” Disease Problem with Goldilocks Molecules In this episode, Christian Schafmeister, Founder and President of Third Law Molecular, reveals a new class of therapeutics designed to target what most consider “undruggable” diseases—conditions like Alzheimer’s, certain cancers, and rare genetic disorders. Christian explains the science behind spiroligomers—modular, mid-sized molecules that act like molecular LEGOs, offering the perfect balance between small molecules and ...

1 month ago

30 minutes

Life Sciences 360

What Separates Life Science Startup Winners from Losers?

Why Startups Fail (Hint: It’s Not the Innovation) In this episode, Carlo Odicino, CEO and Founder at One TEAM Partners, shares the real reasons why most early-stage life sciences companies struggle to survive—and it has nothing to do with bad science. Learn the hidden pitfalls of scaling too fast, confusing innovation with execution, and chasing too many priorities at once. Carlo offers practical strategies for building focus, setting boundaries, and creating a people-first culture that act...

1 month ago

38 minutes

Life Sciences 360

Pandora's Box of Secrets EXPOSED in Drug Pricing Transparency!

The Hidden Math Behind Drug Pricing: Why Patients Pay More Than They Should In this episode, Michael Grosberg, VP of Product Management at Model N, breaks down the complex drug pricing ecosystem—revealing how rebates, PBMs, and outdated pricing models shape what patients actually pay. You’ll learn how Pharmacy Benefit Managers (PBMs) really operate, why list prices are misleading, and how pricing negotiations impact patient access. Michael also unpacks the mechanics behind patient assistanc...

2 months ago

30 minutes

Life Sciences 360

A CCO’s Brutally Honest Advice if You Want to Succeed in Pharma Commercialization

Early Commercialization Strategies That Actually Work (Especially for Startups!) In this episode, John Harlow, Chief Commercial Officer at Melinta Therapeutics, shares real-world strategies for how lean pharma startups can win the commercialization game—without Big Pharma budgets. Discover how small companies can pivot fast, creatively optimize distribution, and make strategic decisions without endless red tape. John breaks down the critical mindset shift from R&D to commercial readiness...

2 months ago

31 minutes

Life Sciences 360

Digital Health Expert: THIS is the No.1 Roadblock to Healthcare AI Adoption

Healthcare AI adoption is transforming the way we address risk, confidentiality, and patient care. In this episode, RJ Kedziora, co-founder of Estenda Solutions talks about the practical steps to safely integrate AI in clinical workflows. Learn how to manage data privacy, mitigate algorithmic bias, and keep a human in the loop to prevent misdiagnoses. Discover real-world strategies for using AI ethically, from ambient listening to second-opinion checks, and why it’s irresponsible not to har...

2 months ago

35 minutes

Life Sciences 360

Tired of Supply Chain Errors? Here’s the Fix: Drug Serialization for DSCSA Compliance

Drug serialization is at the heart of modern pharmaceutical supply chain security. In this episode Michael Rowe, Senior Director of DSCSA and Serialization Services at TwoLabs, talks about the critical role of drug serialization and DSCSA compliance in safeguarding the pharmaceutical supply chain. Michael explains how unique serial numbers, standardized data, and digital traceability are revolutionizing how drugs are tracked from manufacturer to pharmacy. Discover real-world challen...

3 months ago

39 minutes

Life Sciences 360

Why Equitable Healthcare is the KEY to Better Health

Equitable healthcare is the key to bridging health gaps and creating better patient outcomes. In this episode, Amy West, Principal, Advisory Services at HitLab, share her insights on how technology, digital health, and data can reshape access to care—especially for underserved communities. Learn how addressing social determinants, using remote patient monitoring, and integrating wearables can empower patients and reduce disparities. From real-world examples to actionable insights, Amy sha...

3 months ago

22 minutes

Life Sciences 360

Can AI Help Doctors Find Cancer Faster?

Have you ever wondered if AI could help doctors find cancer faster and more accurately? In this episode, we explore OmniScreen, an AI-powered biomarker tool that is revolutionizing cancer diagnostics. Joe Oakley, a pathologist and expert in digital pathology, explains how OmniScreen was trained on 3 million digital slides to detect cancer biomarkers with higher precision and speed. He shares how AI is reducing testing time, preserving tissue samples, and improving early cancer detection. We a...

3 months ago

36 minutes

Life Sciences 360

Why Science Marketing Will Make Your Company EXPLODE in 2025?

Have you ever wondered why marketing in the life sciences industry is so different from traditional marketing? In this episode, we dive deep into the power of science marketing, the impact of brand storytelling, and how companies can successfully position their products in a competitive market. From publishing content to collaboration with industry, we'll show you how to harness the power of science marketing for success. Why do some breakthrough innovations never reach their full potential,...

3 months ago

44 minutes

Life Sciences 360

Why Most New Drugs Don't Launch: The Hidden Challenges in Pharma

Have you ever wondered why so many new drugs fail even after years of research and billions in investment? In this episode, we dive deep into the challenges of drug commercialization, the role of AI in pharma, and the biggest mistakes companies make before going to market. Our guest, Dan Cummings, is a leading expert in go-to-market strategy, having worked with top health tech, medtech, and biotech startups. He shares insider insights on why even successful clinical trials don’t guarantee a p...

4 months ago

37 minutes

Life Sciences 360

Why 55% of Clinical Trials Fail – The Truth About Drug Development

Have you ever wondered why so many clinical trials fail before reaching the market? In this episode, we dive deep into the hidden challenges of clinical trials with Rob Freishtat, President and Co-Founder of Uncommon Cures and a professor at George Washington University School of Medicine and Health Sciences. Rob shares insider knowledge on why over 55% of clinical trials fail, the high costs of drug development, and how misaligned priorities between researchers, regulators, and sponsors can ...

4 months ago

43 minutes

Life Sciences 360

How to Get Quick Access to GLP-1 Medications without Health Insurance ft. Dr. Jonathan Kaplan

In this episode of Life Sciences 360, we dive deep into the world of GLP-1 medications with Dr. Jonathan Kaplan. We discuss weight management, how these medications work, their impact beyond weight loss, and the ethical considerations surrounding their use. Dr. Kaplan shares his insights on the healthcare industry's evolving landscape, the economic implications, and why these medications are changing everything from cosmetic surgery to chronic disease management.Chapters:00:00 Introduction &n...

7 months ago

41 minutes

Life Sciences 360

Astellas Pharma’s Approach to Cell and Gene Therapy

In this episode of LifeSciences 360, we dive into the fascinating world of cell and gene therapy manufacturing with Carlos Yuraszeck. With over 16 years of experience, Carlos shares his deep insights into the unique challenges, opportunities, and innovations in the field, offering a detailed look into what it takes to bring life-saving therapies to patients. We cover everything from the design of manufacturing facilities to the complexities of quality systems, patient-centric innovations, and...

7 months ago

36 minutes

Life Sciences 360

ISPE’s Role in Shaping the Future of mRNA and Personalized Medicine

In this episode of Life Sciences 360, we dive into the evolution of pharmaceutical and biotech manufacturing with our guest, Scott, a seasoned expert with nearly 30 years of experience working with industry giants like Novartis, Biogen, Thermo Fisher, and Merck. Scott shares insights on cell culture technology, mRNA vaccines, and the challenges and innovations in scaling biotech facilities. Discover the impact of collaboration and how organizations like the International Society for Pharmaceu...

7 months ago

34 minutes

Life Sciences 360

Balancing Leadership Roles in a High-Stakes Industry with Taggart McGurrin

Welcome to another episode of Life Sciences 360! Today, we're diving into the intricate world of life sciences leadership with a special guest who's worn nearly every hat in the industry—Taggart McGurrin. Starting in finance, transitioning to law, and tackling leadership roles across strategy, operations, and regulatory affairs, Taggart McGurrin brings a unique perspective on how to navigate the high-stakes environment of life sciences.In this episode, we cover:The Complexities of Life Scienc...

7 months ago

30 minutes

Life Sciences 360

Why Antimicrobial Resistance Is the Biggest Challenge in Public Health

In this episode of Life Sciences 360, host Harsh Thakkar sits down with Marc Sheetz, Associate Dean of Research at Midwestern University's College of Pharmacy, to discuss the growing concern of antimicrobial resistance and the field of pharmacometrics. Marc sheds light on how pharmacometrics is shaping the future of medicine by using predictive models to personalize dosing, making drug treatments more effective while reducing toxicity. This episode dives deep into the intersection of pha...

8 months ago

41 minutes

Life Sciences 360

The Secret to Better Medications: Standardizing Pharmacogenomics (PGx) Testing

Imagine knowing how your body will respond to a medication before you even take it! In this episode, Harsh Thakkar interviews Sarah Rogers, co-founder and president of the American Society of Pharmacovigilance (ASP) and an Assistant Professor at Texas A&M. Together, they dive deep into the fascinating world of pharmacogenomics—how your genetic makeup affects your response to medications. They discuss the challenges of pharmacogenomic testing, real-world examples of adverse drug reactions,...

8 months ago

29 minutes

Life Sciences 360

Life Sciences Marketing Agency CEO on How to Combine Storytelling and Science for Impact

In this episode, Harsh Thakkar welcomes David Ormesher, CEO of CG Life, a leading marketing agency in the life sciences and pharmaceutical sectors. David shares over 30 years of experience in life science marketing and storytelling. From startups to large enterprises, CG Life helps companies blend complex science with compelling stories to resonate with patients, healthcare professionals, and investors.David discusses his entrepreneurial journey, how CG Life specializes in biopharmaceutical m...

8 months ago

36 minutes

Life Sciences 360

Could Worms REALLY Be the Key to Curing Autoimmune Diseases?

In this episode, we dive deep into a fascinating topic worm-derived therapeutics with our special guest Andrea, the founder and CEO of Holoclara. Did you know that autoimmune and allergic diseases were rare before the 1900s? What changed? Andrea shares groundbreaking insights into how worms, which have lived inside humans for millions of years, secrete molecules that could balance our immune system and help us tackle these diseases.From her early research days at Caltech to founding Holoclara...

8 months ago

29 minutes