In this episode of Innovate and React  Anne Mayer, a PhD researcher at Goethe-Universität Frankfurt, explains how solid-state nuclear magnetic resonance (NMR) spectroscopy works and how she uses this analytical method for protein studies. We dive into the fascinating world of NMR—from the basics of nuclear spins and magnetic fields to the complex hardware challenges of solid-state NMR. Anne shares how she investigates membrane proteins and microbial rhodopsins, revealing how solid-state NMR provides insights into protein dynamics and optogenetics. We also discuss the importance of fundamental research, future developments in solid-state NMR, and the interdisciplinary collaboration behind cutting-edge chemical research.

In this episode of Innovate and React, Dr. Leonardo Santoni, a postdoctoral researcher at UCL and a science content creator, shares his insights into the fascinating world of metal-organic precursors for low-temperature metal deposition. He presents his PhD research on aluminum complexes for printed electronics, highlighting the challenges of precursor design, deposition techniques, and the potential of sustainable and user-friendly alternatives to pyrophoric materials. In the second part Leonardo gives his opinion on science communication how short form videos can make chemistry accessible for a broader audience.

In this episode of Innovate and React, Theresa Köffler from BEST – Bioenergy and Sustainable Technologies in Vienna is talking about how to turn waste into fuel. We explore the fascinating role of Fischer-Tropsch synthesis for producing sustainable fuels. From the development of demonstration plants to the integration of syngas from biogenic feedstocks, Theresa shares insights into the future of sustainable aviation fuel (SAF) and decentralized energy systems. The episode covers both the technical challenges and the broader implications for climate-friendly energy independence.

In this episode we discuss the critical role of methanol synthesis and hydrogen energy carriers in the energy transition. Florian, a scientific advisor at Fraunhofer ISE, explains his work in sustainable synthesis processes and the significance of hydrogen as a renewable energy source. We delve into the technical challenges of methanol synthesis using CO2 and hydrogen, the importance of dynamic operation and the purity of the syngas feedstock. Florian also highlights the strategic advantages of utilizing green methanol and advanced synthesis processes for industrial applications and future energy systems, as well as the potential for power-to-X technologies.

This episode is a dive into the dynamic world of hydrogen and its pivotal role in the future of clean energy. Key topics covered include the challenges of intermittent renewable energy sources, the mechanics and benefits of hydrogen as an energy carrier, the hurdles in hydrogen production and infrastructure, and the promise of converting hydrogen into transportable compounds like ammonia and methanol. The episode also explores the potential for hydrogen to revolutionize various industries and offer energy independence.

In this episode of Innovate and React we look at the interface between biology and chemistry. Alexandra, a biochemist studying mitochondrial biogenesis, shares her journey from moving to Germany, and ultimately diving into biochemistry. The conversation delves into the complex processes of mitochondrial function, including their role in energy production, calcium signaling, and apoptosis (programmed cell death). Alexandra discusses her current research on the ER SURF pathway and its implications for understanding protein transport, which could potentially lead to breakthroughs in treating diseases like cancer and Parkinson's. The episode emphasizes the interconnectedness of chemistry and biology and the importance of fundamental research in advancing scientific knowledge.

Are you thinking about pursuing a PhD in chemistry and have wondered if its with the struggle? In this episode of 'Innovate and React', we discuss the personal and professional journey of pursuing a PhD and share our motivations for studying chemistry. We discuss the challenges and surprises encountered during our PhD journey, and the important skills we developed through teaching and research. Every journey is different and depends on many different things. We give a glimpse into our experience with doing a PhD in chemistry and how it can be worth it.

In this episode of Innovate and React, I am talking with Justus Reitz, a chemist from TU Dortmund University, about the limitations of the HSAB (Hard and Soft Acids and Bases) concept in predicting reaction outcomes. We explore an alternative approach using the nucleophilicity scale developed by the Mayr group, which offers a more accurate prediction method. Justus shares insights from his PhD research on stabilizing highly reactive molecules, particularly the synthesis and stabilization of diazoalkenes. We discuss how the Mayr nucleophilicity scale can facilitate understanding and controlling chemical reactions, bridging the gap between theoretical concepts and practical applications. For more check out innovateandreact.com

How can we make pharmaceutical synthesis greener and more efficient? In this episode of Innovate and React, we dive into the world of organic chemistry with Dr. Nikolas Jankowski to explore an alternative to gold catalysis. While gold catalysts are known for their high selectivity and efficiency, their cost, environmental impact, and challenges in industrial applications call for new solutions. Nick shares his research on acid-promoted cyclization using hexafluoroisopropanol (HFIP) as a unique solvent, mimicking some of the effects of metal catalysts. We discuss the breakthroughs that led to a more efficient synthesis of oxazoles, molecules with promising pharmaceutical applications. Tune in as we uncover the intersection of fundamental research, reaction optimization, and the future of sustainable chemistry.

This Episode give a short introduction into the future content of the podcast. For more informations visit www.innovateandreact.com, where you will find all episode and additional content for each episode.