In this episode Justin and Mark delve into the intricate relationship between depression and substance use. They explore the differences between major depressive disorder and temporary sadness, emphasizing the self-medication hypothesis where individuals turn to substances to alleviate emotional pain. The conversation highlights the vicious cycle created by substance use, leading to deeper feelings of depression. Mark shares his personal journey of recovery, illustrating the importance of making small, intentional changes in lifestyle to build a fulfilling life. The episode concludes with a focus on the significance of hope and resilience in the recovery process.