Join Dr. Emily Cooper, Andrea Taylor, and Mark Wright on Fat Science as they unpack the complexities of dosing GLP-1 medications for metabolic health and weight management. Dr. Cooper emphasizes the importance of an individualized approach, debunking the myth that higher doses or faster titration always lead to better outcomes.
The team addresses listener questions about how and when to increase doses, highlight the risks of rapid escalation, and discuss the nuanced ways these drugs impact metabolic health beyond just weight loss. Real-life experiences and thoughtful, science-backed guidance will help you navigate your own journey with metabolic dysfunction and medication.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.com.
Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
Join Dr. Emily Cooper, Andrea Taylor, and Mark Wright on Fat Science for a special mailbag episode answering listener questions about metabolic health. Dr. Cooper explains the difference between mindful and mechanical (timed) eating, especially for those using medications like Zepbound.
The team also addresses emotional challenges tied to frequent eating, societal fat shaming, and the complexities of medication side effects for those on GLP-1 agonists and antipsychotics. Real experiences and practical advice help shed light on fueling your body, breaking free from diet culture guilt, and navigating complex emotions on the journey to better health.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.com.
Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright tackle the urgent issue of deep funding cuts to scientific research in the United States. Dr. Cooper shares firsthand insight on how these changes are affecting patient care and scientific integrity, highlighting the pressures researchers face—including censorship and loss of resources at institutions like the NIH.
The conversation sheds light on how misinformation, government interference, and reduced diversity in studies threaten the future of metabolic, cancer and public health research. Listeners will better understand why research matters for everyday health, and what’s at stake when critical projects lose funding.
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Current Medical Reporting
Nutrition Information
Nutrition for Mortals Podcast with Dietitians: Matt and Jen
Infectious Diseases, Immunizations
Kevin Hall Research
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, send an email to dr.c@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us atinfo@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright dive into the world of blood fats—unpacking what cholesterol numbers really mean for your health. They break down HDL (the “good” cholesterol), LDL (the “bad” cholesterol), triglycerides, and spotlight the often-overlooked lipoprotein(a), a genetic risk marker with significant consequences for heart health. The team dispels myths about fats in our diet, covers the impact of lifestyle and genetics, and explores how advanced testing can reveal hidden risks. You’ll come away understanding which fats matter most, why particle size counts, and what actions can help manage your numbers and protect your heart.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, send an email to dr.c@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
Diabetes Wake-Up Call: The Silent Epidemic
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright take on a troubling statistic—half of American adults are either diabetic or prediabetic, and for those with prediabetes, 8 in 10 don’t know it. Think about your own family. The odds are one in two of your loved ones are at risk.
The good news is diagnosing diabetes is easy, and in many cases it’s reversible. Dr. Cooper breaks down the tests you should get, the numbers to look for and the top treatments. Taking control of your diabetes risk just could save your life.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, send an email to dr.c@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright continue exploring the top ten positive things you can do for your metabolism, focusing on steps five through one. With an honest and approachable discussion, this episode sheds light on essential topics like endocrine disruptors, nutrition, sleep, body image, and why the focus should be on health, not weight. Get practical advice for positive changes you can implement in your daily life.
Key Takeaways:
Endocrine Disruptors – Learn about EDCs and MDCs, their widespread presence, and steps to minimize exposure for better metabolic health.
Nutrition for Health, Not Weight Loss – Shift your focus to fueling your body and maintaining a positive relationship with food, emphasizing nutrition over diet restrictions.
Sleep and Sleep Apnea – Understand the critical role of sleep in metabolism, and consider sleep apnea testing to improve metabolic function and overall well-being.
Body Image – Address the influence of societal pressures and focus on positive self-image to support metabolic health, being mindful of language around children.
Focus on Health, Not Weight – Highlight the importance of prioritizing health metrics over weight, and recognize the limitations of using BMI as a sole indicator of health.
Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, send an email to dr.c@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
n this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright break down their top ten lifestyle strategies to enhance your metabolic health. They critically discuss powerful yet straightforward approaches that can significantly improve metabolism. The focus is on easy-to-implement, applicable tips, from knowing key health numbers to managing stress effectively.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, send an email to dr.c@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the human connections in metabolic medicine. With special guest Alisha, a nurse practitioner at the Cooper Center for Metabolism, the episode delves into how patient-provider relationships have a profound impact on metabolic health outcomes.
If you're interested in how the world of metabolic medicine is evolving and want a human-centered perspective, this episode is a must-listen. You’ll walk away with a better understanding of how interconnected our body’s health systems are and why personalized care matters.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, send an email to emily@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
On this episode of Fat Science, it’s time to hear from some of you, our listeners. Dr. Emily Cooper, Andrea Taylor and Mark Wright are joined by two loyal listeners, Scott and Heidi. The episode explores personal anecdotes and transformative moments thanks to a deeper understanding of metabolic health and its broader implications. It also shows you don’t have to have Metabolic Syndrome to benefit from understanding the science connected to it.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, send an email to emily@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright delve deeper into the topic of compounded metabolic drugs.
Dr. Cooper addresses criticisms from listeners about the previous discussion and provides insights into the economic reasons driving people towards compounded drugs. She also dissects the ethics and economics of the diet industry transforming into a subscription medicine model and the role of insurance in accessibility to metabolic treatments.
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Important Update: Changes in GLP-1 Medication Availability and Compounding Regulations
This episode was recorded before recent regulatory developments regarding GLP-1 medications. As of our current information:
The FDA has determined that shortages have been resolved for all formulations of tirzepatide (marketed as Mounjaro and Zepbound) and semaglutide (marketed as Rybelsus, Ozempic, and Wegovy). Consequently, compounding these medications is no longer legally permitted under FDA regulations.
Additionally, Novo Nordisk has expanded its patient assistance program by implementing enhanced coupon discounts across all Wegovy dosage strengths to improve affordability and access to match Lilly's efforts for Mounjaro and Zepbound access.
Please note that regulatory policies and manufacturer programs regarding these medications continue to evolve. For the most up-to-date information, we recommend consulting current FDA announcements and manufacturer websites.
Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright open the mailbag and answer questions from listeners all over the world.
Dr. Cooper provides expert insights into complex questions about metabolic health, covering topics including metabolic dysfunction, the effects of chemotherapy on metabolism, a discussion of GLP-1s and those trying to get pregnant and the role of iodine in the diet.
Engaging and informative, this episode also arms you with the vocabulary and understanding needed to discuss metabolism with your healthcare provider.
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the intricate metabolic ties to Polycystic Ovarian Syndrome (PCOS). Dr. Cooper provides expert insight into how understanding these links can transform what seems like a permanent condition into a reversible one.
“ I feel like there's so much despair around PCOS when it actually doesn't have to be a long-term condition,” says Dr. Cooper. “I know some of that desperation comes from the infertility piece of it… so it's really important to calm down the (metabolic) dysfunction to be successful in fertility.”
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
On this episode of Fat Science, it’s time to let go of the old paradigm “calories in, calories out.” Join hosts Dr. Emily Cooper, Andrea Taylor and Mark Wright as they kick CICO to the curb.
The idea that a person’s weight is determined only by the ratio of calories consumed and calories burned is an over-simplification and often not true, especially for people with metabolic dysfunction.
Dr. Cooper reveals the real key to weight management is not calorie counting but understanding metabolic function influenced by the neuroendocrine system. Through personal stories and insights, they explore why diets don’t work and how acknowledging the complexity of metabolism can lead to better health.
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Personal Stories & Practical Advice:
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Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the world of compounded drugs. These are medications prepared by pharmacists to meet specific needs of patients when commercially-available products are not an option. Changes in dose, accommodating patients with allergies or sensitivities and drug shortages are some of the reasons the FDA allows compounded drugs to be made and sold.
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Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
n this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore cravings and the role they play in metabolic dysfunction.
If you watch some drug company commercials these days, you’d think cravings are the culprit for obesity. In reality, they are just a symptom of a deeper metabolic problem.
This episode of Fat Science uncovers why this oversimplification is not just misleading but harmful to those struggling with metabolic dysfunction.
Join us as we explore the science behind cravings, debunk common myths and highlight the importance of understanding your metabolic health.
Key Takeaways:
Not Just an Overeating Problem: Learn why targeting cravings alone is not the answer to managing weight and metabolic health.
Metabolic Dysfunction Explained: Discover how metabolic dysfunction manifests in various forms, such as irregular appetite signals, and why addressing the root cause is crucial for effective treatment.
The Role of Medications: Dr. Cooper breaks down commonly-prescribed medications like Contrave, Qsymia, and Saxenda—explaining their true function in strengthening metabolic pathways rather than merely suppressing cravings.
Misleading Advertising: Understand the detrimental effects of current advertising campaigns that focus on willpower and cravings and how they perpetuate weight stigma and misinformation.
Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore one of the most contentious topics in the world of health and fitness: the definition and measurement of fat.
BMI (Body Mass Index) has long been the standard, but recent studies have called its efficacy into question.
Dr. Cooper reveals why BMI can be a flawed indicator of health, exploring alternate measurements like waist circumference and body composition while discussing their limitations and potential misuses.
This episode highlights the real issue: identifying and treating metabolic dysfunction and achieving true health beyond just numbers on a scale or tape measure.
Key Takeaways:
BMI: A Flawed Metric? Dr. Cooper reveals the limitations of BMI. She shares intriguing insights into how factors like muscle mass and gender-specific body composition can skew BMI readings and recounts fascinating stories from her career, including a case where an Olympic athlete was classified as obese purely based on BMI.
The Lancet's Insight. The team discusses a recent paper by the esteemed Lancet Commission, which argues for de-emphasizing BMI in favor of other health indicators. They dive into the importance of looking at the complete clinical picture, including blood sugar swings, energy levels, and more.
Anecdotes and Real-life Experiences. Andrea Taylor shares her journey of struggling with various diets until discovering metabolic dysfunction as the root problem.
Insurance and Medical Ethics. Discover the ethical dilemmas of using BMI for decisions on insurance coverage and medical treatments. Mark brings attention to startling cases where statistically healthy individuals were denied life insurance based on high BMI.
Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore five New Year’s resolutions you can make (and not break) for a healthier 2025.
The conversation shifts away from unattainable goals and toward practical steps for enhancing overall well-being in the new year.
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Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright field questions from listeners. Throughout the show, our hosts highlight the importance of compassionate, science-based medical care and underscore the significance of finding healthcare providers who address metabolic issues as medical, not lifestyle, concerns.
Among the topics addressed:
Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright take a comprehensive look at the current FDA-approved medications designed to treat metabolic dysfunction and what may be approved next.
Dr. Cooper discusses the range of factors that determine whether these essential drugs are available for those who need them. Government approval, drug company strategies and insurance company policies all play a role.
Key Takeaways:
Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright reveal how metabolic lab tests are crucial in diagnosing, understanding and treating metabolic dysfunction.
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Resources:
Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.
If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.
Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/
