
This episode reviews the Endocrine Society’s 2025 guideline updates on managing primary aldosteronism after initial screening.
• When suppression testing is indicated or unnecessary
• Cortisol cosecretion in adrenal adenomas and surgical planning
• Role of adrenal vein sampling (AVS) in determining laterality, with rare exceptions
• Treatment strategies for unilateral vs bilateral disease
• MRA therapy, titration approach, and importance of renin response