In this episode, we break down recommendations 41 to 44 from the 2025 American Thyroid Association guidelines on differentiated thyroid cancer management. Key topics include:

• Patient counseling on the small risk of second primary malignancy after RAI

• Baseline labs: complete blood count and kidney function before RAI therapy

• Reproductive considerations: pregnancy precautions, nursing patient guidance, and fertility counseling

• Adjuvant external beam radiotherapy (EBRT) for high risk cases, balancing locoregional control with potential toxicity