Recorded live at HFSA 2025, hosts explore the evolving landscape of heart failure endpoints, focusing on the significance of oral diuretic intensification in outpatient care.

In this episode of Don’t Miss a Beat, Javed Butler, MD, joins hosts Muthiah Vaduganthan, MD, MPH, and Steve Greene, MD, for a breakdown of the EMPACT-MI trial, including primary results, secondary findings, how data from DAPA-MI and EMPACT-MI complement each other, and what is next for the SGLT2 inhibitor class. Key Highlights: 00:00 - Intro 01:57 - Trial Design and Results 07:00 - Inclusion Criteria and Patient Characteristics 10:53 - Primary Results of EMPACT-MI 14:34 - Subgroup Analyses 15:27 - Implications for Post-MI Patient Population 19:53 - Takehome Messages for Care 23:39 - Kidney Outcomes in Post-MI Patient Population

In this episode of Don’t Miss a Beat, hosts sit down at ESC HFA to discuss key takeaways from the ACC's expert clinical decision pathway and preview HFpEF data scheduled to be presented during the meeting.