Digital Pathology Podcast

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Digital Pathology Podcast

Aleksandra Zuraw, DVM, PhD

169 episodes

21 hours ago

Send us a text Can one AI system learn from every organ — and teach us something new about all of them? In this edition of DigiPath Digest #31, I explore how artificial intelligence is transforming pathology across multiple organ systems, revealing connections that help us diagnose faster, more consistently, and more accurately than ever before. From glomerulonephritis to hepatocellular carcinoma, AI is no longer confined to a single specialty — it’s becoming the connective tissue between the...

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Natural Sciences

Health & Fitness,

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Send us a text Can one AI system learn from every organ — and teach us something new about all of them? In this edition of DigiPath Digest #31, I explore how artificial intelligence is transforming pathology across multiple organ systems, revealing connections that help us diagnose faster, more consistently, and more accurately than ever before. From glomerulonephritis to hepatocellular carcinoma, AI is no longer confined to a single specialty — it’s becoming the connective tissue between the...

Show more...

Natural Sciences

Health & Fitness,

Episodes (20/169)

Digital Pathology Podcast

169: AI Across Organ Systems: Kidney, Liver, Colon, Bladder, and Beyond

Send us a text Can one AI system learn from every organ — and teach us something new about all of them? In this edition of DigiPath Digest #31, I explore how artificial intelligence is transforming pathology across multiple organ systems, revealing connections that help us diagnose faster, more consistently, and more accurately than ever before. From glomerulonephritis to hepatocellular carcinoma, AI is no longer confined to a single specialty — it’s becoming the connective tissue between the...

1 day ago

37 minutes

Digital Pathology Podcast

168: Smarter Slides: How AI Is Reshaping Kidney, Thyroid & GI Pathology

Send us a text If artificial intelligence can match—or even surpass—our diagnostic accuracy, what happens to the role of the pathologist? That’s the question I explore in this episode of DigiPath Digest #30, where I break down three fascinating papers showing how AI is changing the way we diagnose, classify, and predict outcomes in renal transplant biopsies, thyroid cytology, and gastrointestinal cancers. These studies don’t just prove AI’s potential—they reveal what it means for us, the huma...

1 week ago

25 minutes

Digital Pathology Podcast

167: Why Accuracy Matters in Digital Pathology Podcast with Keith Wharton, Jr.

Send us a text Why do some pathologists still hesitate to trust digital slides—even after the FDA says “yes”? Because accuracy in digital pathology isn’t just about pixels—it’s about precision, validation, and confidence. In this episode, I talk with Dr. Keith Wharton, MD, PhD, Global Medical Director at Roche Diagnostics, about how the Roche Digital Pathology DX system earned its FDA clearance for primary diagnosis—and what that means for the field. We explore the science and strategy behind...

1 week ago

1 hour 36 minutes

Digital Pathology Podcast

166: Future of Pathology AI, Training & The Next Generation of Diagnostics

Send us a text Live from Pathology Visions 2025 in San Diego, I share highlights from Day 2 of the world’s leading digital pathology conference, where experts explored how AI, empathy, and training are shaping the next generation of pathologists. This episode captures the shift from technology as a tool to technology as a bridge — helping us connect with patients in more meaningful ways. What I Talk About 1️⃣ From Pixels to Patients We’ve built the infrastructure; now it’s about applying it....

3 weeks ago

28 minutes

Digital Pathology Podcast

165: How AI Is Changing Cancer Diagnosis Insights from PathVision 2025

Send us a text Live from Pathology Visions 2025 in beautiful San Diego, I sat down with Imogen Fitt from Signify Research to explore how AI, digital pathology, and interoperability are transforming the way we diagnose cancer and deliver patient care. The conference theme, “From Pixels to Patients,” perfectly captures this year’s shift — from theoretical discussions about AI to real-world implementation and measurable outcomes. We’re no longer just asking “what can AI do?” — we’re seeing how i...

3 weeks ago

22 minutes

Digital Pathology Podcast

164: What Happens to Human Expertise When AI Takes Over in Medicine

Send us a text Will AI make doctors and specialists less skilled—or even replace them? That’s the question I explore in this episode of DigiPath Digest #29. As someone working where AI meets digital pathology, I’m both excited and cautious about how automation shapes our skills and professional identity. In this episode, I discuss two studies that ask tough questions about AI, expertise, and the future of medicine. What I Talk About: 1️⃣ Endoscopist Deskilling After AI Exposure (Lancet, 202...

4 weeks ago

53 minutes

Digital Pathology Podcast

163: Digital Diagnostics Summit 2025 Innovation in Action - Conference Update

Send us a text What if climbing the digital pathology “mountain” isn’t about reaching the summit alone—but knowing where base camp is, and who you bring with you? In this episode, I take you inside the Digital Diagnostic Summit in Park City, hosted by Lumea, where fewer than 100 digital pathology leaders gathered to share their journeys, challenges, and solutions. From resilient metaphors of Everest climbs to practical strategies for workflow ownership, clinical trials, and AI-powered b...

1 month ago

30 minutes

Digital Pathology Podcast

162: How Color Impacts Every Diagnosis |Color Calibration in Digital Pathology w/ Tom Kimpe (Barco) and Monika Lamba Saini

Send us a text What if up to 35% of the diagnostic color data on your pathology slides never reaches your eyes—just because of your monitor? In this episode, sponsored by Barco, I sit down with Dr. Monika Lamba Saini (ADC Therapeutics) and Tom Kimpe (Barco) to uncover why color calibration in digital pathology isn’t optional anymore—it’s critical for diagnosis, efficiency, and AI readiness. Highlights: [00:03:42] Monika’s path from CROs to biopharma and why color consistency matters in clini...

1 month ago

1 hour 25 minutes

Digital Pathology Podcast

161: 7 Secrets to Smarter AI in Cancer Care | Lessons from NCCN Summit

Send us a text 7 Counterintuitive Secrets from NCCN’s 2025 AI in Cancer Care Summit When the National Comprehensive Cancer Network (NCCN) gathers healthcare leaders, people listen. I attended the 2025 Policy Summit on the evolving AI landscape in cancer care—and walked away with insights that were raw, practical, and surprisingly hopeful. Instead of hype or overpromising, cancer care leaders shared honest strategies for implementing AI responsibly and effectively. In this episode, I break dow...

1 month ago

35 minutes

Digital Pathology Podcast

160: AI in Medicine: Neuropathology, Renal Disease, Hematology & Cytology

Send us a text What if the way we quantify pathology is more guesswork than science? In this episode of DigiPath Digest, I take you through the latest research where AI is not just supporting but challenging traditional methods of image analysis in neuropathology, nephrology, hematology, and cytology. From Boston brain banks to Mayo Clinic kidney models, we look at how advanced AI compares to human vision—and where it already outperforms us. Episode Highlights: [00:02:49] Neuropathology image...

2 months ago

25 minutes

Digital Pathology Podcast

159: What If Your AI Tool Is Lying: Hidden Bias in Pathology Algorithms

Send us a text What if the AI tools we trust for cancer diagnosis are not always correct? This episode of DigiPath Digest takes on the uncomfortable but critical question: can AI “lie” to us—and how do we verify its performance before adopting it in clinical practice? Highlights: [00:02:00] Foundation models in action: Deployment of a fine-tuned pathology foundation model for EGFR biomarker detection in lung cancer—reducing the need for rapid molecular tests by 43%.[00:08:41] Bone marrow AI m...

2 months ago

27 minutes

Digital Pathology Podcast

158: Multimodal Magic AI’s Role in Lung & Prostate Cancer Predictions

Send us a text What if AI could predict cancer outcomes better than traditional methods—and at a fraction of the cost? In this episode, I explore how multimodal AI is reshaping lung and prostate cancer predictions and why integration challenges still stand in the way. Episode Highlights with Timestamps: [00:02:57] Agentic AI in toxicologic pathology – what it is and how it could orchestrate workflows.[00:05:40] Grandium desktop scanners – making histology studies more accessible and efficient...

2 months ago

28 minutes

Digital Pathology Podcast

157: How Academic Pathology Programs Can Prepare for AI | UPMC Podcast

Send us a text “AI in Pathology Isn’t Coming — It’s Already Here. Are You Ready?” From confusion to clarity — that’s what this episode is all about. I sat down with Drs. Liron Pantanowitz, Hooman Rashidi, and Matthew Hanna to dissect one of the most important and comprehensive AI-in-pathology resources ever created: the 7-part Modern Pathology series from UPMC’s Computational Pathology & AI Center of Excellence (CPAiCE). This isn’t just another opinion piece — it's your complete guide to ...

2 months ago

38 minutes

Digital Pathology Podcast

156: Digital Pathology and AI in Cancer Grading, T-Cell Imaging & Biomarkers

Send us a text Can AI Grade Cancer Better Than Us? The Truth About T-Cell Imaging, Biomarkers & Digital Pathology Disruption You think Saturday mornings are for coffee? Try diving into bone marrow morphology, organ donor kidney biopsies, and AI-driven metastasis detection at sunrise. That’s how I do it—and you’re invited to join. Welcome to another data-packed episode of DigiPath Digest, where we explore the latest frontier in digital pathology and AI. This time, I reviewed some of the m...

2 months ago

34 minutes

Digital Pathology Podcast

155: AI Pathology & Genomics_ A New Benchmark for Predicting Gene Mutations

Send us a text AI Pathology & Genomics: A New Benchmark for Predicting Gene Mutations If you still think visual quantification is “good enough” in pathology, think again. In this 27th episode of DigiPath Digest, I break down four transformative abstracts that show how AI is shifting our diagnostic landscape—from breast cancer segmentation to fibrosis assessment, and all the way to spatial immunology and the evolving immunoscore. If you’re still relying on manual scoring, static staging s...

2 months ago

23 minutes

Digital Pathology Podcast

154: AI in Pathology: Advances in Prostate, Bladder & Endocrine Cancer

Send us a text If our visual scoring is still based on gut feeling, how do we scale precision? In this week’s DigiPath Digest, I explored four new AI-focused papers that could reshape how we diagnose prostate, bladder, gastroesophageal, and endocrine cancers. From automated IHC scoring to predicting urethral recurrence post-cystectomy, these studies highlight the growing value—and responsibility—of integrating AI into our pathology workflows. And yes, I also reveal where to get my histology-...

2 months ago

20 minutes

Digital Pathology Podcast

153: Can GPT-4o Classify Tumors Better Than Us? AI-Powered Pathology Insights

Send us a text If we don’t learn to work with LLMs now, we might end up competing with them. 🧠 In this week’s DigiPath Digest, I return to our Journal Club to unpack the latest research on AI in tumor classification, focusing on GPT-4o, LLaMA, and other LLMs. Can these models really outperform traditional tools when analyzing pathology reports? Surprisingly—yes. But don’t panic. This episode is about understanding what LLMs actually bring to the table, how they’re being evaluated, and what w...

2 months ago

19 minutes

Digital Pathology Podcast

152: AI in Pathology, ML-Ops, and the Future of Diagnostics – 7-Part Livestream 7/7

Send us a text AI in Pathology: ML-Ops and the Future of Diagnostics What if the most advanced AI models we’re building today are doomed to die in the machine learning graveyard? 🤯 That’s the haunting question I tackled in the final episode of our 7-part series exploring the Modern Pathology AI publications. In this session, I explored machine learning operations (ML-Ops)—what they mean for digital pathology —and why even the most brilliant algorithm can fail without proper deployment strateg...

2 months ago

42 minutes

Digital Pathology Podcast

151: Ethics and Bias Considerations in AI – 7-Part Livestream 6/7

Send us a text Can We Ever Eliminate Bias in AI for Pathology? Every time we think we’ve trained a “neutral” algorithm, we discover our own fingerprints all over it. Our biases. Unconscious. Systemic. Data-driven. And if we ignore them, AI won’t just fail—it will fail patients. Welcome back, my digital pathology trailblazers! In this sixth episode of our 7-part AI in Pathology series, we tackle one of the most uncomfortable yet necessary conversations: Ethics and Bias in AI and Machine Learni...

2 months ago

42 minutes

Digital Pathology Podcast

150: AI in Pathology – Regulatory Aspects of AI – 7-Part Livestream 5/7

Send us a text The Most Overlooked Risk in AI for Pathology? It’s Not What You Think… Welcome, my trailblazing digital pathologists! In this episode, I dive headfirst into the regulatory maze of Artificial Intelligence (AI) in pathology, covering global frameworks, safety risks, ethics, and the future of software as a medical device. While regulation might not be the flashiest part of AI, ignoring it could cost us innovation—or worse, patient safety. We’re on Part 5 of our 7-part AI in Pathol...

2 months ago

42 minutes