It’s truly an exciting time. The information and science surrounding the microbiome is exploding. It seems that a day doesn’t pass without some new, interesting insight emerges on microbiome questions, providing us with unprecedented insights and strategies to get better control over health, weight management, aging, etc. Look at what we are accomplishing, for example, with our cultivation of L. reuteri and L. crispatus. But it also means that misinformation, misinterpretation, an...

When the first Wheat Belly book was released in 2011, it quickly leapt to centerstage, gaining a huge worldwide following. Millions of copies of the book were sold in 37 countries, the conversation was featured in major media from network news to Dr. Oz to . I don’t believe that this was due to my personal charm or charisma, but because it worked: people experienced unexpected and substantial health and weight loss benefits even if such things had eluded them for years. Well, over those...

While CT heart scans are becoming increasingly popular to generate a coronary calcium score as a gauge of coronary atherosclerotic plaque and thereby risk for heart attack, there is actually a treasure trove of other useful information provided by the scan—but often not reported to you. In this episode of the Defiant Health podcast, I therefore help make you aware of the wealth of information provided by a CT heart scan that can empower you further in maintaining health and preventing h...

Inulin is a common fiber, the fiber found in root vegetables like onions, garlic, shallots, asparagus, jicama and many other foods. Humans lack the digestive enzymes, however, for metabolizing inulin, but microbes living in your gastrointestinal track are able to metabolize it. When beneficial microbes metabolize inulin, they convert it to fatty acids with numerous beneficial effects on gastrointestinal, brain, and metabolic health. But, when undesirable microbes metabolize inulin, bad things...

Here are what I call "The Guardrails of Diet,' i.e.., metabolic markers that tell you whether your diet is genuinely healthy or not. Too many people put too much stock in either a single marker like blood glucose, or the wrong marker like LDL cholesterol that takes you down the path of health disruptions: weight gain, visceral fat expansion, protein glycation, insulin resistance, formation of VLDL particles, cause you to rely on unhealthy foods, even increased risk for heart disease and other...

Conventional healthcare and dietary advice are, unfortunately, virtually useless in providing effective strategies on how to manage blood pressure naturally and nutritionally. They have, for instance, the DASH diet that can reduce systolic and diastolic blood pressure by a few millimeters but not more. They provide bland advice like lose weight or move more. Yet there are effective strategies that you can adopt that powerfully reduce and typically normalize blood pressure. Such strategies may...

Small intestinal bacterial overgrowth, or SIBO, is now rampant, a virtual nationwide epidemic, a condition now carried by around 50% of the population. If you have food intolerances, fibromyalgia, restless leg syndrome, are overweight or obese, have irritable bowel syndrome, an autoimmune condition, atrial fibrillation or numerous other common conditions, it is highly likely that SIBO is either the original cause or at least an exacerbating factor. You can take all the antiinflammatory drugs,...

Bakers, breadlovers, even purported health information authorities such as the Mayo Clinic all spread the claim that all the problems associated with consumption of foods made of wheat are eliminated or significantly reduced by sourdough fermentation. Is this true? In this episode of the Defiant Health podcast, Let’s take each of those claims made, one by one, and examine the evidence to see if there is any truth behind them. _____________________________________________________________...

We’ve been urged to include plenty of dietary fiber in our daily routines, fibers that come from vegetables, legumes, grains and other plant sources. But there is an animal-sourced fiber that has nearly disappeared from the modern human diet: hyaluronic acid. Hyluronic acid has nearly disappeared from the diet because it is primarily sourced from animal products, especially organ meats like brain, skin, and tongue. But hyaluronic acid is a fiber crucial for the health of many human orga...

LDL cholesterol, apoprotein B, saturated fat, TMAO, statin cholesterol drugs: Over the last 40 years, we have been inundated with misguided advice on how to reduce your risk for coronary heart disease, i.e., risk for such things as heart attack, need for heart procedures such as stent implantation or bypass surgery, or sudden cardiac death, serious and often life-threatening events. Has it worked? 80 million Americans now take statin drugs to reduce cholesterol yet there has been no meaningfu...

Go to any supermarket and you will see the impressive variety of products in the dairy aisle labeled "yogurt." You have a mindboggling collection of choices: non-fat, low-fat, full-fat, flavored, unflavored. Single-serve cartons, quart containers, squeezable tubes, jars. Will consuming any of these products change your life in any significant way? Will you be heathier, have better bowel health, skin health, metabolic health, mental health? Let’s discuss why, no, you will not experience ...

The practice of immersing your body in ice water is growing in popularity based on claims of improved mood and well-being, muscle recovery after exercise, even longevity. But this ignores the well-established fact that sudden cardiac death is a real risk due to coronary spasm, causing heart attack, and unstable heart rhythms due to a situation called autonomic conflict. There are a growing number of lawsuits that have been filed for the many sudden cardiac deaths that have occurred. So let’s ...

Over 50% of Americans are, at any one time, trying to lose weight. So it’s understandable that the GLP-1 agonist drugs like Ozempic and Mounjaro have become so popular, given their spectacular upfront results. Others have used reduced calorie diets in their various forms: counting points, assigning foods red, yellow, or green lights, meal replacement products, etc. Or bariatric procedures like lap-band, jejunoileal bypass, or gastric bypass. But there is a lot that people are not told about t...

I first met Dr. Eric Westman at a low-carbohydrate meeting a number of years ago where he discussed an extremely important and insightful human clinical trial he had conducted in which he counseled participants with type 2 diabetes to follow a very low-carbohydrate, essentially ketogenic, diet. He was almost prohibited from conducted the study because some colleagues felt it was too dangerous. Nonetheless, the study was completed and demonstrated that type 2 diabetic participants no longer ne...

We all recognize that American healthcare is a badly broken system. Wildly overpriced, exploitative, with a focus on pharmaceuticals and medical procedures to the exclusion of basic issues such as nutrition, the role of nutrients, and the microbiome. Can we expect doctors, healthcare executives, pharma or medical device executives to find better solutions? I highly doubt it. One of the problems plaguing conventional delivery of healthcare is that doctors lack the time, knowledge, and fr...

Over the past decade, most of us have converted our home lighting to light-emitting diode (LED) bulbs, as they save a significant amount of energy, requiring 75-90% less energy than older incandescent lights. Personally, I converted the 50 or lightbulbs in my house to nearly all LEDs.Most current LEDs emit, of course, visible light. But they also emit a significant amount of blue light and very little red and infrared (IR), in contrast to old-fashioned incandescent bulbs that emit some blue a...

I’ve touched on the topic of endotoxemia in past episodes of the Defiant Health podcast. In this episode, let’s dive deeper into this topic that is absolutely crucial to understanding and managing SO many aspects of health, from subduing anxiety and panic, to depressive, to joint pain and skin rashes, to gastrointestinal conditions, even weight management. What is endotoxemia? Fecal microbes, so-called Gram-negative species because of the way these microbes take up stain for examination...

I’ve been showing thousands of people how to restore this microbe lost by the majority of modern people, Lactobacillus reuteri. But, of all the spectacular improvements in health we can gain by managing our microbiomes, such as an increase in empathy and generosity, reduction in anxiety and depression, deeper sleep, increased libido, restored youthful musculature and strength, the females in my audience have repeatedly said something like, “Well, that’s all well and good, but I’m mostly inter...

I’ve spent some time reflecting back on all my years practicing in hospitals, often not sleeping for extended periods, sometimes days, covering hospitals floors and ICUs, resuscitating people who experienced cardiac arrests, taking them to the cath lab to open arteries, but also witnessing people with all sorts of other health conditions: cancers, wound infections, sepsis, delirium, the various stages of dementia, and hundreds of other debilitating disease. I now recognize that, looking...

Those of you who follow my discussions that started with the Wheat Belly series of books already know that there is a long list of reasons why humans made an enormous blunder when we first resorted to the consumption of the seeds of grasses, meaning wheat and related grains. We know this from the anthropological record of human disease, we know this from modern science that has exposed the many problems that arise with their consumption from tooth decay to arthritis. But in my many conversa...