Join us for a fascinating conversation with Dr. Chad Pozarycki, PhD in analytical chemistry and astrobiology, as we dive into the cutting-edge science behind searching for life beyond Earth. In this episode, we explore groundbreaking research on how biosignature molecules—such as amino acids and ATP—can accumulate and persist in extreme, hypersaline brine environments analogous to those found on Mars, Europa, and other planets.Dr. Pozarycki explains the unique analytical challenges of working with highly salty samples, discusses innovative techniques like capillary electrophoresis and high-resolution mass spectrometry, and offers key advice for scientists developing the next generation of space-ready instruments. If you’re curious about how planetary scientists actually analyze samples from Mars or icy moons, or are interested in the intersection of analytical chemistry, planetary exploration, and astrobiology, this episode is for you!🔬 Topics covered:- Analytical methods for detecting biomolecules in salt-rich planetary environments- Overcoming salt-interference in chromatography and mass spectrometry- Method validation in extreme conditions- Adapting scientific instruments for use on Mars rovers and Europa landers- Career and practical advice for aspiring analytical chemists and astrobiologistsDon’t miss Dr. Pozarycki’s insights on the next frontiers for miniaturized analytical instruments and what it takes to prepare for future space missions.Listen now to discover how planetary analog research on Earth paves the way for discovering life elsewhere in our solar system!#Astrobiology #AnalyticalChemistry #SpaceExploration #PlanetaryScience #Chromatography #MassSpectrometry #Biosignatures
🧪 Transform Your Understanding of Modern Chromatography & AI!
Join us for an eye-opening conversation with Professor Dwight Stoll from Gustavus Adolphus College as he reveals how his team is revolutionizing liquid chromatography through high-throughput data collection and machine learning. With over 43,000 retention measurements and groundbreaking research spanning three major publications, Prof. Stoll is pioneering the future of analytical chemistry.🔬 What You'll Learn:- How short columns (5mm vs 100mm) dramatically increase measurement throughput while maintaining accuracy- The evolution from HSM1 to HSM3 models and their predictive capabilities - Why selectivity ratios are more stable than absolute retention factors- The "Manhattan Project of Chromatography" - building massive retention databases- Key challenges: column drift, mobile phase standardization, and precision trade-offs- Career advice for researchers at the intersection of chromatography and data science📊 Key Highlights:- 43,329 total retention measurements across 13 stationary phases- Revolutionary "feed injection" method for high-throughput analysis- Improved isomer selectivity predictions - crucial for pharmaceutical analysis- The holy grail: predicting retention from molecular structures🎯 Perfect For:- Analytical chemists and chromatographers- Data scientists interested in chemistry applications- Graduate students and researchers- Pharmaceutical industry professionals- Anyone curious about AI applications in science🔗 Connect with Prof. Stoll:- Gustavus Adolphus College Chemistry Department- Research focused on liquid chromatography and 2D-LC#Chromatography #MachineLearning #AnalyticalChemistry #AI #DataScience #Research #HPLC #Pharmaceutical #Chemistry #ScienceThis interview showcases cutting-edge research that's transforming how we approach method development in liquid chromatography. Don't miss this glimpse into the future of analytical chemistry!
Join David Oliva on the Concentrating on Chromatography podcast as he interviews Edward Faden, Vice President and co-owner of MAC-MOD Analytical, a leading provider of chromatography solutions since 1986. In this insightful discussion, Edward shares the history and expertise of MAC-MOD, based in Chadds Ford, Pennsylvania, and dives deep into the critical challenges of analyzing PFAS (per- and polyfluoroalkyl substances), often called "forever chemicals."Key topics include:- The pervasive nature of PFAS contamination in both environmental and laboratory settings.- Surprising sources of PFAS contamination identified in standard lab setups, from gas line tubing to everyday consumables.- The essential role of the PFAS Delay Column in ensuring accurate analysis by minimizing background interference.- Best practices for labs starting PFAS analysis to reduce contamination risks from day one.- Exciting developments in rapid sample pre-screening methods to prevent cross-contamination.Edward also discusses why PFAS are so widespread—used in products like non-stick cookware and waterproof clothing since the 1940s—and the ongoing struggle to manage their environmental persistence. Whether you're a chemist, environmental scientist, or simply curious about the impact of forever chemicals, this conversation offers valuable insights into cutting-edge analytical solutions.Don't miss out on learning about MAC-MOD's innovative approaches and future plans for PFAS analysis. Subscribe for more expert interviews and chromatography content!#Chromatography #PFAS #ForeverChemicals #EnvironmentalScience #LabAnalysis
Join us for an in-depth conversation with Dr. Eamonn Clark, postdoctoral researcher at the University of Hawaii, Mānoa and the Water Resources Research Center, as he shares his journey in water research and laboratory innovation.In this episode:- Dr. Clark introduces his work on water treatment and disinfection byproducts, including research following the Red Hill fuel spill in Oahu.- A behind-the-scenes look at the development of a home-built nitrogen blowdown evaporator—why it was needed, how it was designed, and who can benefit from building their own lab equipment.- Discussion of workflows for PFAS analysis, the importance of accessible analytical tools, and the impact of DIY solutions in low-resource settings.- Insights into other homemade lab instruments, the role of 3D printing and PCB design, and the value of community science in water quality monitoring.- Reflections on the broader impact of water research, community engagement, and the importance of making science accessible to all.Key topics covered:- Water Resources Research Center and its mission- Analytical methods for PFAS and disinfection byproducts- Step-by-step overview of building a nitrogen evaporator- Who should consider DIY lab equipment- The future of homemade scientific tools and citizen science- Community outreach and the real-world impact of water researchWhether you’re a scientist, student, or simply curious about how research labs innovate on a budget, this episode offers practical advice and inspiration for building your own scientific equipment and making a difference in your community.Check out for links to Dr. Clark’s technical note and additional resources on DIY lab equipment and water research:- https://pubs.rsc.org/en/content/articlelanding/2025/ay/d4ay02118e/unauth- https://pubs.rsc.org/en/journals/articlecollectionlanding?sercode=ay&themeid=9bc2db53-354c-4a55-84eb-93fcae875044- https://blog.organomation.com/blog/inaugural-homemade-evaporator-contest-results-the-peak-of-ingenuity
Dr. Haleigh Boswell, Research Chemist at Chevron, joins the Concentrating on Chromatography podcast to discuss her fascinating career journey and cutting-edge analytical work in the energy industry. In this in-depth interview, Dr. Boswell shares:🔬 Technical Insights:- How two-dimensional gas chromatography (GCxGC) differs from traditional GC and why it's revolutionary for complex sample analysis- Applications of GCxGC in analyzing hydrocarbon and renewable matrices- Detector selection strategies (FID, SCD, NCD, TOF-MS) for different analytical challenges- Sample preparation considerations for complex energy industry matrices🎯 Industry Applications:- Real-world problem-solving in refinery operations and catalyst development- Non-targeted analysis for trace contaminants in renewable feedstocks- Process optimization and quality control in energy production- Safety considerations and instrument maintenance in industrial settings📈 Career Journey:- Transition from forensic science undergraduate studies to analytical chemistry- Moving from academia to industry: challenges and adaptations- The importance of networking in scientific careers- Advice for graduate students considering industry positions🏢 Behind the Scenes at Chevron:- Day-to-day responsibilities as a subject matter expert (SME)- Collaborative work across multiple R&D teams- Modernizing analytical instrumentation in a legacy company- Balancing innovation with business needs and safety requirementsThis episode provides valuable insights for analytical chemists, graduate students, and anyone interested in the practical applications of advanced chromatography techniques in industrial settings[#Chromatography #AnalyticalChemistry #EnergyIndustry #GCxGC #CareerAdvice #ChemistryPodcast
In this episode of Concentrating on Chromatography, host David Oliva interviews Dr. Petr Vozka, Assistant Professor at California State University, Los Angeles, about his journey establishing the Complex Chemical Composition Analysis Lab (C³AL).Dr. Vozka shares how he built his research facility during the pandemic, focusing on creating opportunities for first-generation and underrepresented undergraduate students. Learn about the groundbreaking LECO-C³AL partnership that provides students with hands-on experience using advanced comprehensive two-dimensional gas chromatography (GC×GC) instrumentation.The conversation explores:- Building a cutting-edge analytical chemistry lab during challenging circumstances- Creating research opportunities for underrepresented undergraduate students- The innovative fingerprint aging research in collaboration with the Hertzberg-Davis Forensic Science Center- How multidimensional chromatography enables detection of thousands of compounds in complex mixtures- The workflow for analyzing fingerprint samples using GC×GC-TOFMS- The advantages of nitrogen generators in laboratory settingsDr. Vozka also discusses the upcoming 17th Multidimensional Chromatography Workshop (MDCW), a FREE conference taking place January 13-15, 2026, in Williamsburg, VA, bringing together experts in multidimensional separation techniques.Visit Dr. Vozka's lab website: https://www.calstatela.edu/research/c3alLearn more about MDCW: https://www.multidimensionalchromatography.com/#Chromatography #GCGC #ForensicScience #AnalyticalChemistry #Fingerprints #MDCW #CalStateLA
Eugene Oga, a PhD student in Analytical Chemistry at the University of North Dakota, joins David Oliva to discuss his innovative research on silicone sealant degradation using evolved gas analysis and thermal desorption-pyrolysis gas chromatography. With his background in materials chemistry and current focus on analytical techniques, Eugene shares insights into how these advanced methods can characterize material breakdown over time, with significant implications for the construction industry and beyond.Eugene's Background and Research FocusEugene Oga is pursuing his PhD in Analytical Chemistry at the University of North Dakota, following his Bachelor's and Master's degrees from the University of Buea in Cameroon. His academic journey began with a focus on materials chemistry before transitioning to analytical chemistry, recognizing that material properties and performance depend heavily on proper characterization.His current research employs advanced analytical techniques like evolved gas analysis and pyrolysis gas chromatography to understand how materials break down over time and identify the specific fragments produced during degradation. This work aims to provide recommendations to manufacturers about potential improvements to their processes.Understanding Structural Sealant Glazing and Its ImportanceStructural Sealant Glazing (SSG) plays a critical role in modern construction, particularly in buildings that extensively use glass and metal. Eugene explains that sealants are thick liquids used to bind different construction materials together.These sealants serve multiple important functions, including preventing air infiltration, moisture penetration, and enhancing building stability. While studies have estimated how long sealants and buildings should last, they often don't explain the actual breakdown mechanisms. Eugene's research aims to fill this gap by identifying which components are lost over time and how this degradation occurs, ultimately enabling better prediction of failure and development of solutions.Different Failure Modes and Analytical ApproachesEugene identifies several categories of sealant failure that require different analytical approaches:1. Adhesive/cohesive failures: These occur when materials don't properly bind together, often due to surface preparation issues that can be addressed through proper cleaning.2. Chemical degradation: This includes processes like UV exposure, hydrolysis, and oxidation.3. Environmental factors: Temperature fluctuations, moisture, and pollutants can contribute to degradation.4. Physical degradation: Manifesting as cracking, fatigue, and creep.While mechanical analysis can identify physical changes like cracking and strength loss, it doesn't reveal which chemical components are being lost. For all these failure modes, gas chromatography and mass spectrometry prove essential.In all of these different failure modes and causes, gas chromatography and mass spectrometry would be very important to identify the volatile degradation products and the changes that are accompanying the backbone.Innovative Methodological ApproachEugene's research employs a two-step analytical approach that modifies standard GC-MS protocols to accommodate siloxane chemistry:1. Evolved Gas Analysis (EGA-MS): This serves as a rapid screening technique to identify temperature ranges where components evolve.2. Thermal Desorption-Pyrolysis GC-MS: This follows as a verification tool, focusing on the specific temperature zones identified by EGA to perform detailed analysis of components evolving at different temperatures.This sequential approach allows for more targeted analysis and better characterization of degradation products. The method is particularly valuable because it eliminates extensive sample preparation—samples can be analyzed as received, saving significant time and reducing potential preparation errors.
In this enlightening episode of Concentrating on Chromatography, host David Oliva engages in a comprehensive discussion with Lisa Jones, Director of Higher Education Relations at I.W. Tremont Co. and active NAOSMM volunteer, alongside Jim Averso, Co-President at I.W. Tremont and producer of the LabExact brand of laboratory consumables.
The conversation explores critical aspects of laboratory supply management, including best practices for procurement in academic settings, inventory challenges, and the advantages of American-made products. Lisa shares valuable insights from her 27 years of experience at the University of Alabama, highlighting how institutional policies affect purchasing decisions and the complexities of managing laboratory stockrooms. Jim discusses how I.W. Tremont develops products based on real laboratory workflows and responds to researcher feedback.
Key topics include:
The role of NAOSMM (National Association of Scientific Materials Managers) in connecting laboratory managers with quality suppliers
Challenges of cylinder-based nitrogen supply versus on-demand nitrogen generation
The importance of vendor selection criteria including quality certification, inventory availability, and customization capabilities
How academic procurement processes vary between institutions and departments
The value of American manufacturing and family-owned businesses in the scientific supply chain
Whether you're managing university laboratory resources, working in a research facility, or supplying the scientific community, this episode offers practical perspectives on streamlining your supply chain while maintaining research quality and addressing the unique challenges of laboratory operations.
#LabSupplies #AcademicResearch #LabManagement #NAOSMM #ScientificProcurement #ChemistryLab #LabExact
In this episode of Concentrating on Chromatography, host David Oliva interviews Jim Averso, Co-President of I.W. Tremont and manufacturer of the LabExact brand, celebrating their 45th year in business. Jim shares expert insights on the critical role of filtration in chromatography sample preparation.Discover:- Why proper filtration is essential for protecting your expensive HPLC columns- How to select the right membrane type (Nylon, PTFE, PVDF, or PES) based on your sample- Common mistakes researchers make with syringe filters and how to avoid them- The innovative TruPor membrane technology that increases loading capacity while improving flow rates- Tips for preventing membrane intrusion and back pressure issues- The new HandyPrep device that simplifies pre-filtration steps- Advanced techniques like filter stacking for improved sample preparationWhether you're working with HPLC, UHPLC, GC, or other chromatography methods, this conversation provides valuable insights to optimize your workflow and improve analytical results.Jim also discusses the Laboratory Products Association's student engagement committee, which is building bridges between academia and commercial science careers.#Chromatography #LabTechniques #SamplePreparation #HPLC #Filtration #LabExact #ScienceEducation
Join us on the Concentrating on Chromatography podcast as David Oliva interviews Katelynn Perrault Uptmor, PhD about her recent article, "Detangling the Complex Web of GC x GC Method Development to Support New Users." In this insightful conversation, Katelynn explains the basics of comprehensive two-dimensional gas chromatography (GC x GC), its advantages over traditional one-dimensional GC, and shares practical tips for overcoming common challenges faced by new users.Discover how GC x GC vastly increases separation capacity by combining two columns with different stationary phases, allowing for more efficient analysis of complex samples. Katelynn discusses the key steps in method development, including establishing a good one-dimensional separation, using chromatogram modelers to predict peak behavior, and fine-tuning modulator parameters for optimal peak shape and resolution.Learn about choosing the right column combinations for your specific application, understanding the importance of orthogonality between columns, and leveraging resources like literature and expert advice to optimize your setup. Explore real-world applications of GC x GC in fields like forensics, food analysis, environmental science, and petroleum analysis, where this technique is revolutionizing routine analysis.Whether you're a seasoned chromatographer or just starting out, this interview offers valuable insights into the power and accessibility of GC x GC. Katelynn also shares her recent recognition as an Emerging Leader in chromatography and highlights the exciting work of her undergraduate research group. Katelynn is currently Assistant Professor of Chemistry at William and Mary.
Dive into the world of cutting-edge catalysis research with Dr. Roberto Silva Villatoro in this captivating episode of Concentrating on Chromatography. Hosted by David Oliva, General Manager of Organomation, this interview explores how high-resolution mass spectrometry (HRMS) is revolutionizing our understanding of palladium-catalyzed reactions. Key highlights: - Discover how HRMS detects elusive organometallic intermediates - Learn about overcoming air-sensitivity challenges in sample preparation - Explore the implications of off-cycle species in catalytic processes - Gain insights into the future of C-X and C-C bond-forming reactions Whether you're a chemistry enthusiast, a seasoned researcher, or an industry professional, this interview offers valuable insights into the intricate world of catalytic mechanisms. Join us as we uncover the potential for cleaner, more efficient chemical processes and the power of interdisciplinary collaboration in advancing scientific discovery. Don't forget to like, subscribe, and hit the notification bell to stay updated on the latest in chromatography, mass spectrometry, and sample preparation! #Catalysis #MassSpectrometry #ChemistryResearch #Chromatography #ScientificDiscovery
Join us for an insightful interview with Dr. Isaiah Speight, Assistant Professor at William and Mary, as he discusses his groundbreaking work in sustainable chemistry and innovative chromatography techniques. In this engaging conversation, Prof. Speight shares: - His research focus on sustainable chemistry from synthesis, financial, and educational perspectives - The importance of NOBCChE (National Organization for the Professional Advancement of Black Chemists and Chemical Engineers) - How HPLC and flash chromatography enable synthetic chemistry - The advantages of automated flash chromatography systems - Method development processes for new compounds and reactions - Exciting ongoing projects, including 3D-printed mechanochemical reaction vessels and mercury-centered metal-organic frameworks Discover how Prof. Speight's lab is pushing the boundaries of sustainable chemistry while training the next generation of undergraduate researchers. This interview offers valuable insights for chemists, students, and anyone interested in the future of sustainable scientific practices. #SustainableChemistry #Chromatography #STEM #NOBCChE #ResearchInnovation
Dive into the world of environmental toxicology with Andrea Andress Huacachino, a PhD student at the University of Pennsylvania. In this fascinating interview, Andrea discusses her groundbreaking research on PFAS (per- and polyfluoroalkyl substances) and their impact on androgen regulation. Learn about: - The novel finding of PFOA's effect on pre-receptor androgen regulation - Innovative use of radio chromatography in hormone analysis - Challenges in developing HPLC methods for androgen separation - The broader implications of androgen dysregulation on human health Discover how environmental pollutants affect hormones in all humans and why this research matters for everyone. Perfect for science enthusiasts, students, and anyone interested in the intersection of chemistry and human health. #EnvironmentalToxicology #PFAS #Androgens #ChemistryResearch #ScienceInterview
Dr. Caitlin Cain discusses her groundbreaking research on potato taste defect (PTD) in coffee using comprehensive two-dimensional gas chromatography (GC×GC). Learn how this advanced technique revealed 359 class-distinguishing analytes related to PTD, providing unprecedented insights into this complex flavor issue. Key points covered: - Advantages of GC×GC over traditional one-dimensional GC for complex samples - Optimization of headspace solid-phase microextraction for coffee volatile analysis - Surprising findings from the comprehensive volatile profile of PTD-affected coffee - Implications for coffee farmers and the industry in combating PTD Discover how this research is advancing our understanding of coffee chemistry and potentially improving coffee quality worldwide. #CoffeeScience #Chromatography #AnalyticalChemistry #FoodChemistry
Dive into the cutting-edge world of natural product discovery with Jess Deng, a fourth-year PhD candidate at Queen's University. In this engaging interview, Jess discusses her groundbreaking research using ambient ionization mass spectrometry to streamline the discovery of novel fungal metabolites. Key highlights: - Learn about the liquid microjunction surface sampling probe (LMJ SSP) and its advantages - Discover how Jess is tackling the time and resource challenges in natural product research - Explore the effects of light conditions and environmental factors on fungal metabolism - Hear about Jess's exciting work at the Smithsonian Museum of Conservation From rapid screening techniques to machine learning algorithms, Jess shares insights that could reshape the future of pharmaceutical research and biofuel production. Don't miss this fascinating look into the intersection of mass spectrometry, fungal biology, and drug discovery! #MassSpectrometry #NaturalProductDiscovery #FungalMetabolites #PhDResearch #ASMS2024
In this insightful interview, Medicinal Chemist Schyler Odum discusses his work in antibiotic drug discovery and the critical role of Ultra-High Performance Liquid Chromatography (UPLC) in his research. Schyler, a fifth-year graduate student at UTHSC, shares his expertise on: The importance of antibiotic drug discovery in academic institutions How UPLC differs from HPLC and its benefits in chemical analysis Challenges in sample preparation and potential improvements The complexities of synthesizing large molecular weight antibiotics The need for increased support and funding in antibiotic research Schyler also highlights the Gordon Research Conferences as a platform for presenting antibiotic drug discovery work. This video offers valuable insights for chemistry students, researchers, and anyone interested in the future of antibiotic development. #AntibioticResearch #MedicinalChemistry #UPLC #DrugDiscovery #GraduateResearch
Dive into the world of sample preparation with industry expert Wade Hasenour as he shares invaluable insights on rotary evaporation, centrifugal evaporation, and freeze drying. Learn about the latest advancements, challenges, and future trends in sample prep techniques for chromatography. Discover how to choose the right method for your needs, optimize your workflow, and leverage automation for better results. Whether you're a seasoned chromatographer or just starting out, this video offers essential knowledge to enhance your sample preparation skills and achieve more reliable outcomes in your research. #Chromatography #SamplePreparation #LabTechniques #ScientificResearch #massspectrometry
Dive into the cutting-edge world of pharmaceutical analysis with Mark Dennis Retrato, a PhD candidate at Uppsala University. In this exclusive interview, Mark shares his groundbreaking research on developing a novel UPLC-MS method for analyzing phospholipids in total parenteral nutrition (TPN) products. Key highlights: • Innovative UPLC-MS method for phospholipid quantification • Importance of nitrogen evaporation in sample preparation • Unexpected findings in phosphatidylcholine species • Implications for quality control in pharmaceutical manufacturing • Potential impact on patient care and TPN product stability Learn how this research is pushing the boundaries of analytical chemistry and contributing to improved healthcare outcomes. Whether you're a scientist, healthcare professional, or simply curious about advancements in medical technology, this interview offers valuable insights into the future of parenteral nutrition analysis. Don't forget to like, subscribe, and hit the notification bell to stay updated on the latest developments in chromatography and mass spectrometry! #UPLCMS #ParenteralNutrition #PharmaceuticalAnalysis #Chromatography #MassSpectrometry #PhDResearch
Join Organomation's General Manager David Oliva as he interviews Bianca Costa, a PhD researcher from the University of Southern California, about her groundbreaking work on PFAS (per- and polyfluoroalkyl substances). In this in-depth discussion, Bianca shares her experiences and insights on: • The complexities of PFAS sampling and analysis in various environmental matrices • Challenges in method development for PFAS extraction and detection • The use of advanced analytical techniques like LC-MS for PFAS research • Emerging biotechnologies for PFAS remediation and the potential for microbial transformation • Community engagement efforts to assess PFAS exposure in Southern California Discover the latest advancements in PFAS research and the interdisciplinary approach needed to tackle this widespread environmental challenge. Whether you're a researcher, environmental professional, or simply interested in cutting-edge science, this interview offers valuable insights into the world of PFAS and environmental chemistry. #PFAS #EnvironmentalChemistry #WaterQuality #AnalyticalChemistry #Chromatography #Biotechnology #USC
Join us for an interesting interview with Taylor Bias, a leading researcher in the field of mitochondrial proteins, as she discusses her groundbreaking work on mitoNEET and its implications for diseases like Type 2 Diabetes, Parkinson's Disease, and Cancer. In this engaging conversation with Organomation General Manager David Oliva, Taylor shares the challenges she faced in developing analytical methods to study mitoNEET's enzymatic activities and the pivotal role of chromatography techniques like GC-MS and HPLC in her research. Discover how chromatography is evolving in the study of complex proteins and hear about some unexpected findings that have emerged from Taylor's research. For young researchers eager to dive into interdisciplinary studies, Taylor offers valuable advice on navigating this exciting field. Additionally, she addresses common misconceptions about mitoNEET and clarifies its significant role in disease mechanisms. Don't miss this opportunity to learn from an expert about the fascinating intersection of biochemistry, disease research, and advanced analytical techniques!
