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Choosing Science: Stories of Perseverance, Humanity, and Success
Ana-Maria Zamfirescu
12 episodes
3 months ago
Send us a text Fruit flies, scientifically known as Drosophila melanogaster, may appear as common pests, but they have been indispensable to biological research for over a century. These small insects have significantly advanced our understanding of genetics, development, and disease. This discussion explores why Drosophila is a key model organism, highlights its contributions to science, and examines the creative gene names that reflect the ingenuity of researchers. First, let’s clarify: wha...
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Society & Culture,
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Send us a text Fruit flies, scientifically known as Drosophila melanogaster, may appear as common pests, but they have been indispensable to biological research for over a century. These small insects have significantly advanced our understanding of genetics, development, and disease. This discussion explores why Drosophila is a key model organism, highlights its contributions to science, and examines the creative gene names that reflect the ingenuity of researchers. First, let’s clarify: wha...
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Science
Society & Culture,
Documentary
Episodes (12/12)
Choosing Science: Stories of Perseverance, Humanity, and Success
Tiny flies, but big discoveries! How the fruitfly changed humanity's course
Send us a text Fruit flies, scientifically known as Drosophila melanogaster, may appear as common pests, but they have been indispensable to biological research for over a century. These small insects have significantly advanced our understanding of genetics, development, and disease. This discussion explores why Drosophila is a key model organism, highlights its contributions to science, and examines the creative gene names that reflect the ingenuity of researchers. First, let’s clarify: wha...
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3 months ago
17 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Prof. Dr. Mario Capecchi or how to go from being a homeless child to Nobel Prize winner
Send us a text Mario Capecchi was one of the 3 scientists who were awarded the Nobel prize in Physiology or Medicine in 2007 “for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells”. However, him winning the most prestigious prize in science was not the most impressive thing he did in his life. For reference in terms of level of difficulty, it is somewhere above winning a Nobel prize and below surviving academic politics. He ...
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3 months ago
20 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Mice as discovery driver or how to be small, but help achieve great things
Send us a text Mice (17th century- current) Some find them cute, some find them repulsive, and science finds them useful. Mice have been a model organism for a bit over a century and is by far the most used nowadays. Let’s find out what these little creatures did for scientific discoveries and learn cool facts about them at the same time. Resources: https://www.nature.com/articles/s41593-021-00849-x https://www.labome.com/method/Laboratory-Mice-and-Rats.html https://www.sciencedirect....
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1 year ago
19 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Prof. Rita Levi-Montalcini or how to create a completely new science field in one's bedroom
Send us a text Professor Rita Levi-Montalcini (1909-2012) A developmental biologist who left an indelible mark on the field of neuroscience through her groundbreaking discoveries and unwavering dedication to scientific inquiry, despite being forced at one point to conduct her research from the confinements of her bedroom in Turin. From her pioneering research on nerve growth factor (NGF) (which was found to also be involved memory and learning, physical and mental illnesses, and led to antib...
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1 year ago
32 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Williamina Paton Fleming or how to go from being a maid to changing astronomy forever
Send us a text Fleming, Williamina Paton (1857–1911) A single mum, deserted by her husband in a time when women were second class citizens and weren’t allowed to get a higher education, Williamina Paton Fleming rose from the humble position of maid to one of the most famous astronomers in history. She supervised the cataloging of hundreds of thousands of stars, refined the star hunting method and changed the face of astronomy forever. This is the story of an immigrant woman that beat h...
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2 years ago
28 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Prof. Dr. Frits Zernike or how the Nazis did something good by mistake
Send us a text Frits Zernike Although he spent his whole life from birth to retirement in the cities of Amsterdam and then Groningen, his life was far from ordinary. Incredibly intelligent and gifted, having the rare combination of simultaneously being a fine theoretician and skilled experimentalist, Frits Zernike started his scientific journey in astronomy and then applied his findings in microscopy. Before his discovery was recognised and awarded a Nobel prize, the Nazis were the fir...
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2 years ago
30 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Prof. Dr. Lynn Margulis or how to be so good you get to use swearwords in your scientific titles
Send us a text Although now Lynn Margulis is as the historian Jan Sapp has said "as synonymous with symbiosis as Charles Darwin's is with evolution", she faced intense criticism in her lifetime. At the beginning her ideas elicited responses such as, "Your research is crap. Don't ever bother to apply again" and has been intitally rejected by 15 journals, in the end her passion and stubbornness prevailed. Strong in her opinions and unbothered by other people's vitriolic attitudes, she was also ...
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2 years ago
46 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Dr. Walle Nauta or how to stick it to the Nazis while revolutionising neuroscience
Send us a text Dr. Walle Nauta was not only a brilliant neuroanatomist and scientist of the 20th century, but also a selfless, brave soul. He revolutionised research tools in neuroscience, making it possible to better understand one of the biggest mysteries of humankind, our brain. Exigent, but kind, intuitive, but rigorous, and most of all, humble, he lived a life to remember. List of interesting people: John Boren, Joseph Brady, Boyd Campbell, Sven Ebbesson, Ford Ebner, Michael ...
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3 years ago
20 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Dr. Hilde Mangold or how to live your life on fast forward
Send us a text The short but fruitful life of Hilde Mangold produced one of the few doctoral dissertation that has ever been directly linked to a Nobel prize. Hilde performed transplantations of cells from one darker newt embryo (type of amphibian) into a receiver lighter embryo in order to see if the transplanted cells will trigger the formation of parallel body axis that can be distinguished between them by colour. After hundreds of such delicate and complex transplantations, she man...
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3 years ago
27 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Dr. George Washington Carver or how to have God as your lab assistant
Send us a text Born just as slavery was abolished, Dr. George Washington Carver has managed to change the agricultural landscape of America through pure empiricism and perseverance and was one of the first African-American pioneers and inventors who rose all by himself to popularity and international recognition. Take a listen to te biography of a man that has touched many lives only by being his humble but eccentric self and through his geniune admiration of all God's creation.&n...
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3 years ago
31 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Dr. Eng. Eliza Leonida-Zamfirescu (or how to crush your oposition with an ungodly amount of patience and work)
Send us a text Have you ever asked yourself who were the first women that had the courage to go against society's expectations and pursue "unfeminine" careers such as engineering? (the only answer accepted here is "yes", sorry). Then you might be interested in finding out more about one of the first womn engineer, Eliza Leonida-Zamfirescu, a courageous woman who chose science in a time when following such interests were unheard of and frowned upon. She wasn't only gifted with a sharp m...
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3 years ago
17 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Sir John Bertrand Gurdon (or how to succeed at proving people wrong)
Send us a text For the pilot episode of Choosing Science, we are going to learn about a Nobel Prize winner in Medicine who by all accounts of his school teachers shouldn't have even be able to pass a science test. He is a great example of inspiring rebellion and wholesome self acceptance, combined with pure curiosity and scientific passion. I recommend watching the full interview given by Sir Gurdon at the Nobel Prize ceremony: https://www.nobelprize.org/prizes/medicine/2012/gurdon/interview...
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4 years ago
36 minutes

Choosing Science: Stories of Perseverance, Humanity, and Success
Send us a text Fruit flies, scientifically known as Drosophila melanogaster, may appear as common pests, but they have been indispensable to biological research for over a century. These small insects have significantly advanced our understanding of genetics, development, and disease. This discussion explores why Drosophila is a key model organism, highlights its contributions to science, and examines the creative gene names that reflect the ingenuity of researchers. First, let’s clarify: wha...