Between synthetic dyes, air pollution, and environmental toxins, kids have a lot of obstacles in the way of their health. I’m reviewing some top offenders (like synthetic dyes and added sugars) and discussing how to empower our kids to make informed choices.  Study Links:  Synthetic Dyes in Food & Beverages HEPA Filters in LA Schools US Kids Face Deadlier Odds Peanut Allergies & Air Pollution Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters:  00:00 - Introduction  02:20 - Synthetic Dyes + Added Sugars   14:20 - Teaching Kids About Nutrition  20:21 - Toxins, Food Allergies, & Air Quality  22:42 - Kids Health Protocol  24:24 - Screen Time, Social Media & Mental Health  26:22 - U.S. Kids Are Dying at Higher Rates 29:44 - Societal Changes for Better Health 34:41 - Empowering Kids to Make Healthy Choices 

My team and I looked into the biological effects of eating a*s and choking during sex - here’s what we found. I’m also sharing why I monitor my erections - and why this metric is critical for good health and longevity.  Study Links:  Choking During Sex  Overnight Erections Female Erection Cycles  Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters:  00:00 - Introduction  01:15 - Taboos Around Sex  04:50 - Sex is Good For You  08:33 - Choking During Sex  15:06 - Anilingus (Rimming)  22:20 - Sexual Preferences + Microbiome  25:25 - Erection Cycles: Male and Female  34:38 - We Need More Conversations About Sex

Had I protected my body and brain, I’d be wealthier and more successful today. Culture is lying to you — you do not need to martyr yourself to be successful. Here’s how you can avoid making the same mistake I did. Study Links:  Burnout + Heart Attack Risk  Hours Worked + Heart Disease Sleep Deprivation in CEOs Sleep Deprivation in Judges Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters:  00:00 - Introduction  03:11 - Martyring Yourself for Success  15:50 - Study: ‘Overwork Will Kill You’  20:04 - Sleep + Decision Making (Studies)  25:54 - Physical Fitness + Diet (Studies)  28:24 - Treating Health Like Religion 33:30 - Tips for Balancing Work and Health  43:58 - Resting Heart Rate Before Bed  47:06 - Protecting Your Agency 

Society is bathing us in chemicals. From wildfires to 4th of July fireworks, toxins feel inescapable. Here’s what I’m doing to limit exposure and reduce my levels. Show Links:   Blueprint Food Guide: https://blueprint.bryanjohnson.com/pages/blueprint-protocol#food-guide Further Listening:  “How Sauna Detoxified My Body” - Bryan Johnson Podcast  “We Need to Talk About Microplastics” - Bryan Johnson Podcast  Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters:  00:00 - Introduction  01:20 - Fireworks + Toxic Celebrations  12:27 - LA Wildfire Toxins  16:57 - Truth About Air Quality 21:23 - PFAS  31:49 - Reducing Toxins/PFAS 46:11 - Sauna, HBOT & Diet  50:13 - Don’t Freak Out 

International travel is brutal on your mind, body, and sleep. We discuss the recent data and I share my current jet lag protocol (still evolving) to help minimize the damage after long flights. Study Links:  Olympic Athletes + Jet Lag: https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.998484/full Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters:  00:00 - Introduction 01:08 - Where’s Kate?  02:00 - Bryan’s Travel Experiment   03:44 - Debunking the ‘CEO Lifestyle’  06:28 - Why Jet Lag Happens   08:00 - Jet Lag Recovery  14:00 - Improving Sleep  17:07 - Is Fighting Jet Lag Possible?  21:44 - Olympic Athlete Study  24:42 - Travel Rule of Thumb   33:55 - Shifting Your Mindset   35:10 - Setting Limits for Travel   44:25 - Jet Lag Protocol   50:41 - Stimulants During Travel 52:04 - Cryotherapy/Cold Therapy  53:00 - Episode Takeaways

Microplastics are everywhere — even in glass bottles. Should you be worried? Kate, Mike, and I interpret the data to understand the risk. I’ll share how I reduced my own levels by 93% so you can too.   Study Links:  Glass Bottle Study: https://www.sciencedirect.com/science/article/pii/S0889157525005344 Impact on Children: https://www.nejm.org/doi/abs/10.1056/NEJMms2409092 Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ CHAPTERS  00:00 - Introduction 01:27 - No Cause for Alarm (Yet)  02:05 - Microplastics Nuance  04:04 - What Are Microplastics?  05:24 - Science Is Still Emerging  07:39 - Microplastics in Our Bodies  09:51 - Study: Microplastics in Glass Bottles  11:42 - What Can We Trust?  12:53 - Building a ‘Don’t Die’ Society 14:23 - Microplastics in IV Drips 17:11 - Impact on Kids  18:47 - Microplastics in Washing Machines 19:31 - What is ‘Don’t Die’ 21:05 - Bryan’s Microplastics Measurements 22:36 - Total Plasma Exchange / Blood Donation  24:28 - The Water Bottle Dilemma  27:50 - Water Systems / Reverse Osmosis  28:36 - Reducing Microplastic Intake  32:05 - An 80/20 Approach  33:10 - Sauna and Microplastics  35:38 - A Challenge for Humanity  36:15 - Testing Microplastics at Home   37:54 - Bryan’s Upcoming Microplastics Tests  39:03 - Don’t Die Party  39:31 -  Teaching Congress to Sleep

Quality sleep is the highest-return investment I’ve ever made. In this episode we walk you through my exact protocol, so you can cherry-pick what works, experiment, and track gains for yourself.  Study Links:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3902870/ Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 00:00 – What Ruins Your Sleep Most? 01:50 – Sleep in Vegas: A Cautionary Tale 03:45 – How Important Is Sleep? 05:30 – Sleep Deprivation 07:20 – Kernel Willpower Study 09:20 – The 80/20 Of Sleep 10:10 – Being a Professional Sleeper 13:00 – Resting Heart Rate 19:00 – Psychology of Tracking Sleep 22:30 – Heart Rate (Before vs. During Sleep) 25:00 – Wearables 30:00 – Food as the #1 Sleep Killer 33:40 – 10 Rules for Perfect Sleep 44:30 – Bonus Tips 49:00 – Sleep Alone? 51:20 – Sleep + Mental Health 52:40 – Bryan’s Final Plea: Learn to Sleep

At last, we tested sauna for longevity. I’m dropping my sauna protocol and explaining why they are definitely worth the hype. Plus, hear about my first time ever stepping into one, and why it was one of the most difficult — but rewarding — protocols I’ve ever done. Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 00:00 – First Impressions of Sauna 01:30 – Assessing the Sweat Response in Kate and Bryan 03:00 – Why Sauna? The Science Behind the Heat 05:20 – How Sauna Mimics Exercise 08:30 – Early Biomarker Changes with Sauna 12:00 – Protocol Design & Measurement Strategy 15:30 – Bryan’s Difficulties Starting the Sauna Protocol  18:00 – Why Bryan Ices His Testicles in the Sauna 21:00 – Electrolyte Loss & Cramping 24:30 – Dry vs. Wet Sauna 27:00 – Practical Home Sauna Protocol 30:00 – Groups Who Shouldn’t Use Sauna 33:00 – Unexpected Effects of Sauna and Areas to Explore 38:00 – Skin Exposure & Sauna Material Safety 42:30 – Sauna Hygiene & Post-Sweat Protocol 45:00 – Measuring Sweat Toxins 47:30 – Kate and Bryan’s Personal Sauna Habits 49:00 – Sun Damage and Skin Aging with Teens 54:00 – Protocol as Part of a Broader Mission

Dr. Mike Israetel is back. We’re talking about deep work, sharing a brain with AI, strategies for creativity, and how money and fame changed our lives, for better and worse. About Dr. Mike:  Dr. Mike Israetel is an expert in the field of fitness and performance. He’s served as a professor at Lehman College, Temple University, and the University of Central Missouri, teaching exercise science courses focusing on nutrition, strength, and hypertrophy. Learn more at: http://rpstrength.com/mike Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00:00 - Deep Work 0:01:22 - Why Bryan Quit Flying 0:03:36 - Flow States 0:06:03 - ChatGPT & Edibles 0:08:49 - Dr. Mike’s Creative Process 0:14:36 - Everyone’s Creative Triggers  0:20:09 - Messaging Overload 0:25:28 - Fame & Money 0:34:00 - Does Money Make You Happier? 0:39:01 - Fame vs Fortune 0:50:23 - Cancel Culture 0:57:02 - Gratitude, & Identity 1:03:02 - Friendship & Fame

I’ve become the worlds healthiest human. Today I’m sharing more on my longevity protocols and biomarker testing and why that’s an essential piece of the Don’t Die movement. We’re also getting into sperm health and why it’s important to keep your testicles cool.  Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00:00 - Today's Topics 0:04:45 - 1: The Decline of Global Sperm Health 0:08:45 - 2: Bryan’s Metrics and Above-Average Results 0:15:00 - 3: Sperm Health Reveals What?!? 0:19:20 - 4: Sauna, Ice, and Testicle Cooling  0:24:15 - 5: How to Improve Sperm Health 0:30:10 - 6: What Bryan’s Markers Actually Prove 0:35:30 - 7: A Deep Dive into Bryan’s Full Biomarker Testing 0:41:00 - 8: Oral Health, Attachment Loss, and Gum Therapy 0:47:00 - 9: What does 'Most Measured Human' mean? 0:53:30 - 10: Aging Speed, Inflammation, Testosterone 1:07:00 - 11: Where Bryan’s Protocol Needs Improvement 1:12:40 - 12: Viewer Feedback, & The Future of the Podcast

If you’re worried about “dad bod,” listen up. We’re discussing a new study among mice. We review the new data behind dad bod and how you can prevent it. We also dive into bone health and why you should care, and the healthiest way to get your protein.    Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00 - What Is Dad Bod & Why It Matters 0:56 - Fat Cells, Testosterone & Evolution 4:44 - Culture & Aging 9:01 - Sleep, Exercise & Diet Insights 10:01 - Bone Density & Biomarkers 15:01 - Bone Health 101 18:01 - How to Rebuild Bone  23:21 - Weight-Bearing Exercise 26:00 - Nutrients That Support Bone Health 31:02 - Creatine & Calcium 35:45 - Protein Deep Dive 47:00 - Why Bryan Doesn’t Eat Meat (And Why That Triggers People)

Is it better to work out at night or in the morning? A new WHOOP study covers new data on evening exercise. Kate, Mike and I also share why lowering your resting heart rate (RHR) may be one of the most powerful strategies for longevity and overall health.  WHOOP Study: https://www.nature.com/articles/s41467-025-58271-x Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00 - Intro 0:58 - New Whoop Study 13:30 - Exercise vs Sleep 16:04 - Is Resting Heart Rate The Most Important Biomarker? 28:50 - How To Lower Resting Heart Rate? 40:36 - Building A Wind-Down Routine 45:44 - What’s A Good Resting Heart Rate?

There’s a new treatment for longevity — one you probably haven’t heard of before. I review my experiments with hyperbaric oxygen therapy (HBOT) and how it dramatically transformed my biomarkers. We’ll also cover the ways air pollution shows up in your body, something I experienced firsthand while traveling in India.   Links and Studies  Analyzing India’s Air Quality: https://x.com/bryan_johnson/status/1863474991142236217 https://x.com/bryan_johnson/status/1864091348179222955 Bryan’s HBOT protocol + results:  https://x.com/bryan_johnson/status/1861085751024484459 https://x.com/bryan_johnson/status/1902044120807567436 Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00 - Intro 1:02 - Hyperbaric Oxygen Therapy (Bryan's Results) 15:37 - India's Air Pollution 23:58 - Air Quality Protocol 29:49 - Have A Plan

What’s the truth when it comes to creatine? And which sleep tracker gets you the best results? Blueprint co-founder Kate Tolo and Blueprint Chief Medical Officer Dr. Mike Mallin join me to discuss the science behind some of the hottest wellness topics to find out which ones are actually worth your time.   UNSW Creatine study: https://www.unsw.edu.au/newsroom/news/2025/03/sports-supplement-creatine-makes-no-difference-to-muscle-gains-trial-finds Andrej Karpathy’s sleep tracker study: https://karpathy.bearblog.dev/finding-the-best-sleep-tracker/ Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00 - Intro 0:41 - 1: Welcome to the Don't Die podcast 2:52 - 2: Dr. Mike’s experience as an ER physician 7:32 - 3: Difference between America and New Zealand ER 9:38 - 4: Dr. Mike on using ChatGPT  13:00 - 5: New study on creatine effectiveness 18:40 - 6: How much creatine to take per day 24:33 - 7: Body awareness 29:33 - 8: Blueprint protocol’s limit in slowing aging 30:57 - 9: Andrej Karpathy’s sleep monitor study 36:10 - Conclusion  

Just how bad is Trevor Wallace’s comedy career for his body? Comedian and host of the podcast “Stiff Socks” talks about his life on the road. I offer Trevor some practical tips to help him look and feel his best.  Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_' Chapters 0:00 - Intro 1:01 - 1: Trevor's Leftover Pasta Breakfasts 4:34 - 2: The Convenience Trap 7:23 - 3: My Practical Health Advice 10:45 - 4: Sleep, Stimulants & Recovery Protocols 14:24 - 5: How to Build a Wind-Down Ritual 19:56 - 6: Plasma Transfusions & Family Experiments 21:00 - 7: Trevor’s 'Biological Age' Test Results

Fitness expert Dr. Mike Israetel shares his take on artificial intelligence, what to consider before trying steroids, and his experience dealing with haters. Dr. Mike Israetel is an expert in the field of fitness and performance. He’s served as a professor at Lehman College, Temple University, and the University of Central Missouri, teaching exercise science courses focusing on nutrition, strength, and hypertrophy. Learn more about Dr. Mike: http://rpstrength.com/mike Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00 - Intro 0:58 - 1: How Mike deals with online fame 8:38 - 2: The future of fitness 18:24 - 3: Why Mike started bodybuilding 21:33 - 4: Mike and his wife’s love story 23:42 - 5: Steroids & side-effects 31:33 - 6: Advice to young people who want to try steroids 40:18 - 7: How “Don’t Die” works 49:38 - 8: AI is getting smarter than us 56:49 - 9: How to plan for the future 59:56 - 10: Mike’s 'biological age' results 1:09:51 - 11: Feedback from Mike 1:18:30 - 12: First meeting 1:25:39 - 13: Should we arm wrestle? 1:36:16 - 14: How Bryan handled his depression 1:40:39 - Conclusion

The Bryan Johnson Podcast is ushering in a new era of being human. In this podcast I am joined by longevity physician Dr. Mike Mallin, my co-founder Kate Tolo, and the occasional guest. We discuss the science-based protocol to help you become your best self. Join us on this journey. New episodes releasing weekly.