BioTalk Unzipped

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BioTalk Unzipped

38 episodes

2 weeks ago

Gregory Austin and Dr. Chad Briscoe unzip, unlock, and uncover, the Stories Behind Medical Progress by sharing the latest and greatest advances in biopharmaceuticals and medical technologies in a fun, entertaining, and enlightening interview format. We bring on innovative leaders across the life sciences. The format is like a conversation you might overhear at the bar or at dinner after a day of great life science talks at a conference, engaging and accessible.

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Episodes (20/38)

BioTalk Unzipped

Fail Fast, Learn Faster: Drug Development in Rare Disease with Dr. Binodh DeSilva

2 weeks ago

31 minutes 28 seconds

BioTalk Unzipped

Unlocking Antibody Development with AI with Dr. Pin-Kuang Lai

1 month ago

17 minutes 52 seconds

BioTalk Unzipped

The Science and Hope of Brain Cancer with Dr. Robert Thorne, Denali Therapeutics

4 months ago

22 minutes 17 seconds

BioTalk Unzipped

Inside AAPS NBC with AAPS President Dr. Russ Weiner

5 months ago

28 minutes 24 seconds

BioTalk Unzipped

Building Successful Life Science Companies with Katrina Rogers

6 months ago

59 minutes 53 seconds

BioTalk Unzipped

Navigating Challenges in Drug Discovery with Dr. Alfred Botchway

7 months ago

51 minutes 52 seconds

BioTalk Unzipped

2024 Year In Review: BioTalk Unzipped

In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe reflect on their journey over the past year, discussing key themes and insights gained from their guests. They explore the humanistic approach to healthcare, the impact of AI in drug development, common threads among successful individuals, personal growth through conversations, and the importance of leadership and mentorship in the industry. The episode concludes with exciting plans for future series focused on drug development and global healthcare innovations.

Thanks to CREO Consulting for hosting this episode!

https://creoconsulting.com/

Dr. Chad Briscoe

https://www.linkedin.com/in/chadbriscoe/

Celerion - https://www.celerion.com/

Gregory Austin

https://www.linkedin.com/in/gregoryaustin1/

Celerion - https://www.celerion.com/

Takeaways

Every sample is a person, a patient, a loved one.
Embrace the fear, take more risks.
The importance of human connection in drug development.
AI is becoming integral in drug discovery and development.
Successful individuals often wish they had taken more risks.
Leadership in the industry is about raising others up.
Mentorship plays a crucial role in professional growth.
Personal growth can come from listening and engaging with others.
Innovative approaches are essential in addressing industry challenges.

Keywords

BioTalk, drug development, AI, mentorship, leadership, podcast, healthcare, innovation, personal growth, industry insights

7 months ago

41 minutes 57 seconds

BioTalk Unzipped

Women in Pharmaceutical Sciences and their Allies with Dr. Ines Santos and Dr. Julie Sable

8 months ago

1 hour 11 minutes 1 second

BioTalk Unzipped

Are AI Doctors coming soon? A Discussion about AI in Medical Devices. - with Dr. Alex Friedman

9 months ago

1 hour 10 minutes 29 seconds

BioTalk Unzipped

Collaborating for Innovation: Biopharma Success with Dr. Nathan Teuscher

9 months ago

31 minutes 39 seconds

BioTalk Unzipped

The Future of Pharmacometrics with Dr. Nathan Teuscher

10 months ago

33 minutes 15 seconds

BioTalk Unzipped

Insights from AAPS PharmSci 360 Live with Dr. Mark Arnold

In this episode of BioTalk Unzipped, host Gregory Austin and co-host Chad Briscoe engage with Dr. Mark Arnold, a distinguished bioanalytical thought leader. They discuss the impact of recent FDA regulations on drug development, the importance of community support through the Samaritan Purse charity, especially on recent hurricane victims, and the exciting advancements in RNA editing technologies. The conversation highlights the collaborative nature of the pharmaceutical industry and the drive behind bioanalytical work, emphasizing the ultimate goal of delivering effective therapies to patients.

Chapters

00:00 Introduction to BioTalk Unzipped at AAPS PharmSci 360

03:45 Samaritan's Purse Charity and Community Impact

05:16 Most impactful talk at AAPS?

11:50 Comparative Analysis of FDA and EU Regulations

17:37 The Drive Behind Bioanalytical Work

22:24 NEW NEWS! - Innovations in RNA Editing and Bioanalysis

Takeaways

The FDA's new rules on lab-developed tests could delay biomarker utilization in clinical trials.
Community support through charities like Samaritan's Purse is crucial during crises.
The importance of collaboration in advancing drug development and bioanalytical methods.
Innovations in RNA editing present new bioanalytical challenges.
The drive to help patients is a key motivator for professionals in the field.

Sound Bites

"I worked on that drug and there's a clear benefit."
"It's getting that new therapy to a patient."
"This is going to change and potentially delay biomarkers."

New News Story:

Wave sees RNA editing validation in early trial results

◦https://www.biopharmadive.com/news/wave-rna-editing-aatd-first-trial-data/729981/

How to reach us:

Please donate to: Samaritan’s Purse

https://www.samaritanspurse.org/

Mark Arnold

https://www.linkedin.com/in/markearnoldphd/

Blog - https://bioanalysisandbiomarkers.blogspot.com/

Dr. Chad Briscoe

https://www.linkedin.com/in/chadbriscoe/

Celerion - https://www.celerion.com/

Gregory Austin

https://www.linkedin.com/in/gregoryaustin1/

ECI - https://eci-rx.com /

Image Credits

AAPS

10 months ago

29 minutes 49 seconds

BioTalk Unzipped

Digital Twins: The Future of Drug Discovery with Dr. Tomáš Helikar

BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe engage with Dr. Tomas Helikar in an exciting discussion on the future of AI, digital twins, and personalized medicine. From mathematical models and immune system simulations to groundbreaking collaborations with the Department of Defense, this episode uncovers how digital twins have the potential to transform drug discovery and clinical trials. Don’t miss insights on the ethical challenges of data privacy, the promise of animal digital twins, and the latest AI breakthroughs like MIT’s Sparrow algorithm!

Chapters

01:00 How the mathematical models work. Normalization and Scaling in Computational Biology

07:55 Focus on the Immune System and Organ Models

09:05 Collaboration with the Department of Defense

11:03 Drug Discovery and Digital Twins

13:43 NEW NEWS! - AI in Drug Discovery: The MIT Sparrow Algorithm

17:51 Future of Digital Twins in Clinical Trials

18:59 Personalized Medicine and Individualized Treatments

23:33 The Potential of Animal Digital Twins

24:59 Building a Research Infrastructure for Digital Twins

26:03 Privacy and Ownership of Digital Twin Data

30:14 Encouraging Publication and Literature Engagement