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BIOACTIVE
Riley D. Kirk, Ph.D.
66 episodes
1 day ago
Dr. Riley Kirk is a cannabis research scientist and educator. She obtained her Ph.D. in pharmaceutical sciences, specializing in natural product chemistry, studying the traditional and contemporary uses of hundreds of medicinal plants. She is currently an assistant associate professor at the University of Rhode Island, has worked as an immunology scientist in the biotech industry, and works in the cannabis industry studying the chemical complexity of cannabis smoke. Riley is also the co-founder of the cannabis research and education non-profit organization called the Network of Applied Pharmacognosy (NAP). Through NAP and on her podcast, Riley uses science as advocacy to research and communicate findings that highlight the unique power of natural products. The goal of Riley’s work is to unite people in the Cannabis industry, academia, and consumers to further the reach of Cannabis education and reduce harm. Riley is passionate about making Cannabis science accessible through social media channels and alternative media which lead to Bioactive; an educational podcast which disseminates the chemistry and pharmacology of natural products. On this bi-weekly podcast, she covers current news and research surrounding cannabis, psychedelics, toxins, pharmaceuticals & other bioactive substances. Listen for special guests highlighting community stories.
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All content for BIOACTIVE is the property of Riley D. Kirk, Ph.D. and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Dr. Riley Kirk is a cannabis research scientist and educator. She obtained her Ph.D. in pharmaceutical sciences, specializing in natural product chemistry, studying the traditional and contemporary uses of hundreds of medicinal plants. She is currently an assistant associate professor at the University of Rhode Island, has worked as an immunology scientist in the biotech industry, and works in the cannabis industry studying the chemical complexity of cannabis smoke. Riley is also the co-founder of the cannabis research and education non-profit organization called the Network of Applied Pharmacognosy (NAP). Through NAP and on her podcast, Riley uses science as advocacy to research and communicate findings that highlight the unique power of natural products. The goal of Riley’s work is to unite people in the Cannabis industry, academia, and consumers to further the reach of Cannabis education and reduce harm. Riley is passionate about making Cannabis science accessible through social media channels and alternative media which lead to Bioactive; an educational podcast which disseminates the chemistry and pharmacology of natural products. On this bi-weekly podcast, she covers current news and research surrounding cannabis, psychedelics, toxins, pharmaceuticals & other bioactive substances. Listen for special guests highlighting community stories.
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Science
Episodes (20/66)
BIOACTIVE
What Happens When A Stoner Scientist Gets Pregnant... My Journey So Far
In this episode, Riley Kirk shares her personal journey through pregnancy, focusing on her experiences with cannabis use, tapering down her consumption, and the emotional and physical changes she faced. She discusses the importance of mental health during this time, the role of her supportive partner, and the diagnosis of intrahepatic cholestasis of pregnancy (ICP). The conversation also touches on the gender reveal process and the complexities of navigating a high-risk pregnancy. In this conversation, Riley Kirk shares her personal journey with Intrahepatic Cholestasis of Pregnancy (ICP), a rare liver condition that can occur during pregnancy. She discusses the emotional and physical challenges she faced, the medical treatments available, and the lifestyle changes she made to manage her symptoms. Riley emphasizes the importance of mental health support and community during this difficult time, and reflects on her experiences as a pregnant woman in the cannabis community. She also expresses gratitude for the support she received from friends and family, and looks forward to continuing the conversation about women's health and pregnancy in future episodes. THE MAIN TAKEAWAY OF THIS EPISODE IS TO BE YOUR OWN ADVOCATE DURING PREGNANCY. PHYSICIANS KNOW A LOT BUT YOU ARE THE EXPERT ON YOUR OWN BODY. (THERE'S ALSO A SECRET SEED GIVEAWAY IF YOU CLICK THE PATREON LINK) Chapters 00:00 Introduction to Pregnancy Journey and Cannabis Use 03:11 Discovering Pregnancy and Initial Reactions 05:55 Tapering Down Cannabis Consumption 08:48 Methods of Consumption and Personal Preferences 12:01 Managing Migraines and Mental Health During Pregnancy 15:11 The Role of Supportive Partners 18:00 Gender Reveal and Early Testing 20:51 High-Risk Pregnancy and ICP Diagnosis 27:14 Understanding Intrahepatic Cholestasis of Pregnancy (ICP) 30:00 The Emotional Toll of High-Risk Pregnancy 33:07 Treatment Options and Medical Anomalies 35:53 Lifestyle Changes and Natural Remedies 40:09 Mental Health and Support During Pregnancy 44:01 Reflections on Pregnancy and Community Support 49:00 Looking Ahead: Future Topics and Conversations Preorder my book Reefer Wellness! ⁠⁠⁠https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156⁠⁠⁠ ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠⁠⁠ www.Patreon.com/Cannabichem⁠⁠⁠ 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem ⁠⁠⁠https://www.appliedpharmacognosy.org/⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices
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6 days ago
55 minutes

BIOACTIVE
The Amazing Coevolution of Monarch Butterflies and Milkweed Plants with Dr. Anurag Agrawal
In this conversation, Host Dr. Riley Kirk and Dr. Anurag Agrawal discuss the intricate relationship between monarch butterflies and milkweed, exploring themes of coevolution, chemical ecology, and the ecological arms race. He explains how monarchs have adapted to survive the toxic compounds in milkweed, the challenges they face due to habitat destruction and pesticides, and the importance of conservation efforts. The discussion highlights the fascinating dynamics of species interactions and the need for community involvement in preserving biodiversity. Chapters 00:00 Introduction to Monarchs and Milkweed 06:32 The Co-evolutionary Dance 11:32 Monarchs vs. Milkweed: The Arms Race 20:14 The Role of Cardiac Glycosides 30:01 Sequestration and Survival Strategies 31:37 The Journey of Monarch Butterflies 37:30 Understanding Monarch Population Decline 46:49 Human Impact on Monarchs and Conservation Efforts 54:01 Exploring Other Fascinating Insects Follow Dr.Agrawal’s research: https://ecologyandevolution.cornell.edu/anurag-agrawal https://agrawal.eeb.cornell.edu/ Read or listen to Monarchs and Milkweed https://www.amazon.com/Monarchs-Milkweed-Migrating-Remarkable-Coevolution/dp/0691166358 Preorder my book Reefer Wellness! ⁠⁠https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156⁠⁠ ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠⁠ www.Patreon.com/Cannabichem⁠⁠ 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem ⁠⁠https://www.appliedpharmacognosy.org/⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices
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3 weeks ago
1 hour

BIOACTIVE
Figuring out how THC works in the brain with Dr. Allyn Howlett
In this episode of the Bioactive Podcast, Dr. Allyn Howlett—renowned neuroscientist and pioneer in cannabinoid research—shares her groundbreaking journey into the study of cannabis and the discovery of the CB1 receptor. Originally focused on neuronal hormones, Dr. Howlett recounts how her curiosity led to one of the most pivotal findings in medical cannabis science: the identification of the brain’s first cannabinoid receptor. She dives into the mechanisms of THC, the function of cannabinoid receptors in the brain and body, and the discovery of the endocannabinoid system. The conversation explores the historical development of cannabinoid research, the barriers posed by the pharmaceutical industry, and the evolving relationship between academia and drug development. Dr. Howlett also discusses the future of cannabinoid science—including targeted therapies, pain relief, and the medical potential of cannabis compounds. This episode offers an essential look at the scientific foundation behind cannabis medicine and its impact on legalization, healthcare, and public perception. 🔬 Keywords: CB1 receptor, endocannabinoid system, THC, cannabis research, Dr. Allyn Howlett, cannabinoid receptors, medical cannabis, neuroscience, cannabis and pain relief, cannabis legalization, targeted cannabinoid therapies. Follow Dr.Howlett's research: https://school.wakehealth.edu/faculty/h/allyn-howlett Preorder my book Reefer Wellness! ⁠https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156⁠ ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠ www.Patreon.com/Cannabichem⁠ 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem ⁠https://www.appliedpharmacognosy.org/⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices
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1 month ago
1 hour 4 minutes

BIOACTIVE
The Science Behind how CBD Works in the Brain with guest Dr. Josh Kaplan
In this conversation, Dr. Riley Kirk and Dr. Josh Kaplan delve into the complexities of cannabis research, particularly focusing on CBD and its therapeutic potential for conditions like epilepsy. Dr. Kaplan shares his journey into cannabis research, highlighting the significance of understanding CBD's mechanisms, the role of GPR55 in seizure management, and the challenges of dosing CBD effectively. They also discuss the entourage effect, the importance of personalized medicine, and the ongoing research into terpenes and their interactions with cannabinoids. The conversation emphasizes the need for further exploration in cannabis research to develop safe and effective therapies, especially for vulnerable populations like children. In this conversation, Josh Kaplan discusses the therapeutic potential of CBD, particularly in relation to traumatic brain injuries and neurodegenerative diseases. He emphasizes the safety of CBD compared to THC and explores its role in preventative treatments. The conversation also delves into ongoing clinical trials, particularly within the NFL, and the challenges faced in cannabis research, including dosing and the variability of individual responses to cannabinoids. Kaplan highlights the importance of understanding the entourage effect and the need for more personalized approaches in cannabis treatment. More about Dr. Kaplan: Dr. Kaplan is an Associate Professor in the Behavioral Neuroscience Program. His expertise is in neurophysiology, neuropharmacology, and animal behavior techniques, which his lab uses to study the therapeutic benefits and developmental consequences of cannabis in pre-clinical rodent models. His research seeks to optimize cannabinoid and terpene compositions to maximize benefit and minimize adverse consequences.  Dr. Kaplan has a strong passion for teaching and communicating science. His scientific writing specializes in the science of cannabis and its medicinal utility. He was included in High Times' 100 Most Influential People in Cannabis (2018) and Cannabis Newsletter's Top 100 (2021). Follow Dr.Kaplan’s research: https://wp.wwu.edu/kaplanlab/ Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 Seed Giveaway Thank you to Royal Queen Seeds and Last Green Valley Seeds for donating to this week's giveaway! To enter, fill out the form below, winners will be selected at random.  https://forms.gle/1vWtsBMGaux9x5Mf6 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Timestamps: 00:00 Introduction to Cannabis Research and Its Importance 03:04 The Journey into CBD and Epilepsy 06:00 Understanding CBD's Mechanism of Action 08:54 The Role of GPR55 in Seizure Management 12:00 Exploring the Entourage Effect 14:53 Challenges in Dosing CBD for Multiple Conditions 18:02 Personalized Medicine and Endocannabinoid System 21:01 Researching Terpenes and Their Effects 24:01 Future Directions in Cannabis Research 34:12 The Therapeutic Potential of CBD 36:34 Traumatic Brain Injury and CBD Research 39:34 Clinical Trials and NFL Studies 48:01 Challenges in Cannabis Research 54:27 Dosing and Efficacy of CBD 01:00:24 The Entourage Effect and Individual Variability Learn more about your ad choices. Visit megaphone.fm/adchoices
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1 month ago
1 hour 10 minutes

BIOACTIVE
The Science of the Dry and Cure Process with David Sandelman from Cannatrol
In this episode of the Bioactive Podcast, Dr. Riley Kirk interviews David Sandelman from Cannatrol, delving into the intricate processes of drying and curing cannabis. David shares his journey into the cannabis industry, emphasizing the importance of controlling environmental conditions to achieve optimal drying and curing results. The conversation explores the science behind water activity, the significance of terpene retention, and the implications of traditional drying methods like the 60-60 method. David highlights the impact of drying rates on the final product and discusses the potential for enzymatic processes to enhance the curing experience. The episode concludes with insights into the variability of different cannabis cultivars and the importance of post-harvest practices in maximizing quality. In this conversation, Riley Kirk and David from Cannatrol delve into the intricacies of drying and curing cannabis, emphasizing the importance of strain specificity and the role of technology in enhancing the quality of cannabis products. They discuss methods for rehydrating overly dry cannabis, adjusting water activity for different products, and effective storage techniques for harvested cannabis. The conversation also touches on the significance of terpenes, the potential for using Cannatrol for other herbs, and the encouragement of experimentation with the technology. David shares insights on achieving consistent drying and curing processes, and the conversation concludes with practical advice for growers. Timestamps  00:00 Introduction to Drying and Curing Cannabis 03:46 The Science Behind Drying and Curing 12:50 Understanding Water Activity in Cannabis 14:43 The Importance of Terpene Retention 21:43 The 60-60 Method: Origins and Implications 26:31 The Rate of Drying and Its Effects 31:05 The Role of Enzymatic Processes in Curing 34:26 Understanding Strain Specificity in Drying and Curing 36:04 Rehydrating Cannabis: Enhancing Quality and Experience 38:41 Adjusting Water Activity for Different Products 41:43 Home Drying and Curing Techniques 43:49 Storing and Managing Harvests Effectively 45:37 The Importance of Terpenes in Cannabis 46:50 Exploring Other Uses for Cannatrol 49:40 Encouraging Experimentation with Cannatrol 51:40 Achieving Consistent Drying and Curing 53:40 Final Thoughts on Drying and Curing Process Learn more from Cannatrol: Instagram @Cannatrol   Website: https://www.cannatrols.com/ Seed Giveaway Make sure to comment the magical words on Instagram to be eligible to win some seeds from OR comment the same thing on the FREE Patreon post. Winners will be notified by next week and the next giveaway will be in two weeks when the next episode of Bioactive drops!  Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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2 months ago
1 hour

BIOACTIVE
Homegrow Made Easy with Jordan River from Growcast
In this conversation, Jordan River shares his journey into the cannabis industry, emphasizing the importance of home growing and the concept of Overgrow, which advocates for more individuals to cultivate their own plants. He discusses the therapeutic benefits of cannabis, the connection to nature, and the role of caregivers in supporting patients who cannot grow for themselves.  The conversation highlights the value of homegrown cannabis compared to dispensary products and the need for community support in the cannabis culture. In this conversation, Jordan River and Riley Kirk delve into the complexities of cannabis cultivation, emphasizing the importance of understanding individual patient needs and the unique responses to different cannabis strains. They discuss the intricate chemistry of cannabis, the significance of focus in cultivation, and the accommodations necessary for growers with physical disabilities.  The conversation also highlights community support for disabled growers, the best practices for transplanting and pot sizes, and the differences between soil choices for outdoor and indoor growing. Finally, they demystify the topic of nutrients, addressing common misconceptions and providing clarity for new growers. In this conversation, Jordan River and Riley Kirk delve into the intricacies of cannabis cultivation, discussing the importance of nutrients, the identification of male plants, and the benefits of feminized seeds. They explore the significance of testing cannabis for cannabinoids and terpenes, as well as effective methods for drying and curing cannabis. The episode concludes with insights on joining the grow community and accessing valuable resources for both novice and experienced growers. Keep up with Jordan & Growcast!  Instagram @Growcast Listen to Growcast on all streaming platforms: Apple, Spotify & All Streaming Platforms Become a member of Growcast: Growcast.com/Membership  Free Growing Guide: Growcast.com/Guide  X: @GrowcastPodcast   Seed Giveaway Make sure to follow @GrowItFromHome and @BioactivePodcast on Instagram to be eligible to win some seeds from OR comment the same thing on the FREE Patreon post. Winners will be notified by next week and the next giveaway will be in two weeks when the next episode of Bioactive drops!  Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Timestamps: 00:00 Introduction and Personal Journey 04:47 The Concept of Overgrow 09:55 The Connection Between Cannabis and Nature 14:58 The Importance of Home Growing 19:57 The Role of Caregivers in the Cannabis Community 25:36 Understanding Cannabis Strains and Patient Needs 28:51 The Complexity of Cannabis and Individual Responses 30:56 Exploring the Unknowns of Cannabis Chemistry 33:55 The Importance of Focus in Cannabis Cultivation 34:22 Accommodating Growers with Physical Disabilities 38:00 Community Support for Disabled Growers 39:07 Transplanting and Pot Sizes for Optimal Growth 44:34 Soil Choices for Outdoor vs Indoor Growing 48:57 Demystifying Nutrients in Cannabis Cultivation 49:37 Understanding Nutrients in Plant Growth 55:49 Identifying Male Plants and Feminized Seeds 01:00:48 Learn more about your ad choices. Visit megaphone.fm/adchoices
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2 months ago
1 hour 12 minutes

BIOACTIVE
Choosing the Right Cannabis Seeds with Dan Nelson from Happy Valley Genetics
In this episode of the Bioactive Podcast, Dr. Riley Kirk and Dan Nelson from Happy Valley Genetics discuss the importance of home growing cannabis and the various types of seeds available. They delve into the differences between photoperiod and autoflower seeds, the benefits of feminized seeds, and what beginner growers should consider when selecting seeds.  The conversation also touches on the evolution of cannabis genetics and the significance of disease resistance in cannabis cultivation. In this conversation, Dan Nelson and Riley Kirk delve into the intricacies of cannabis breeding, focusing on the importance of stable genetics, the challenges of ensuring high-quality seeds, and the differences between commercial and home growing. They discuss the significance of THC percentages versus terpene profiles, the impact of consumer education on the market, and practical tips for seed storage. The episode concludes with an exciting seed giveaway from Happy Valley Genetics, encouraging listeners to engage and grow their own cannabis plants. Seed Giveaway Make sure to follow @Happy_Valley_Genetics and @BioactivePodcast on Instagram to be eligible to win some seeds from Happy Valley Genetics OR comment the same thing on the FREE Patreon post. Winners will be notified by next week and the next giveaway will be in two weeks when the next episode of Bioactive drops!  Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Didn’t win the giveaway but still want to buy seeds from Happy Valley Genetics or talk to Dan, head to https://happyvalleygenetics.com/ Chapters 00:00 Introduction to Home Growing and Seed Giveaway 07:28 Photoperiod vs. Autoflower: Key Differences 18:37 Feminized Seeds: What You Need to Know 25:06 Disease Resistance in Cannabis Genetics 39:10 Understanding High-Quality Genetics 46:13 Commercial vs. Home Growing: Seed Quality Learn more about your ad choices. Visit megaphone.fm/adchoices
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3 months ago
58 minutes

BIOACTIVE
Cannabis Medical Cards with Dr. June Chin from Leafwell
In this episode of the Bioactive Podcast, Dr. Riley Kirk speaks with Dr. June Chin, Chief Medical Officer at Leafwell, about the evolving landscape of medical cannabis.  They discuss the benefits of obtaining a medical card, the differences between medical and recreational cannabis, and the challenges faced by patients, including cost and accessibility. The conversation also delves into the sensitive topic of cannabis use and firearms, recent legal cases impacting this issue, and the importance of research in understanding the benefits of medical cannabis.  Dr. Chin shares insights on the process of obtaining a medical card and the implications for patients traveling with cannabis. In this conversation, Dr. June Chin and Riley Kirk discuss various aspects of medical cannabis, including legal considerations, impairment testing, education for medical professionals, the impact of federal prohibition, and personalized treatment plans.  They emphasize the importance of understanding cannabis strains, integrating cannabis with other medications, and clarifying regulations surrounding medical cards, particularly in Texas. The discussion highlights the need for education and awareness in the cannabis community. ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Keep up with Dr.June Chin and Leafwell: Follow Leafwell on Social media @leafwell_official  Follow Dr. June on IG at @DrJuneChin Head to Leafwell.com to learn more and check regulations in your state.  Head to my link on Leafwell for a discounted medical card:  https://leafwell.com/medical-card?utm_source=cannabichem  Learn more about your ad choices. Visit megaphone.fm/adchoices
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3 months ago
59 minutes

BIOACTIVE
How to Evaluate Quality Cannabis With Certified Ganjier Elizabeth Sage
In this episode of the Bioactive Podcast, host Dr. Riley Kirk sits down with Elizabeth Sage who is a certified Ganjier- which is essentially the weed equivalent to a sommelier in the wine world. In this conversation, Riley and Elizabeth delve into the intricate process of evaluating cannabis, discussing various aspects such as appearance, grinding techniques, flavor profiles, and the importance of set and setting in consumption. They share personal experiences with different strains and emphasize the significance of quality in cannabis products. The discussion also touches on the role of joint construction and the impact of paper types on the smoking experience, culminating in a reflection on their favorite cannabis experiences. In this conversation, Elizabeth Sage and Riley Kirk explore various aspects of cannabis, including best practices for storage, the evaluation of concentrates and edibles, the emerging market for cannabis beverages, pathways to becoming a Ganjier, and the importance of intentional consumption. They discuss the nuances of cannabis quality, the evolving landscape of cannabis products, and the significance of community and education in navigating the cannabis space. ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Keep up with Elizabeth Sage: Visit Elizabeth's Website to learn more at: https://www.elizabethsageadvice.com/ Or follow her on Instagram @TheSageGanjier Or on LinkedIn https://www.linkedin.com/in/elizabeth-sage-416875211/ Thanks for listening & Mad Love! Learn more about your ad choices. Visit megaphone.fm/adchoices
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3 months ago
1 hour 3 minutes

BIOACTIVE
Unlocking the Secrets of Hop Latent Viroid in Cannabis: Dr. Ali Bektaş
In this episode of the Bioactive Podcast, host Dr. Riley Kirk dives deep into groundbreaking cannabis science with world-renowned molecular biologist Dr. Ali Bektaş. Dr. Bektaş has an impressive background in plant biology, microbes, and agriculture, specializing in affordable and distributed systems for detecting nucleic acids in agricultural environments. He has worked extensively with cannabis nurseries and biotech companies as a consultant, staff scientist, and Chief Science Officer. Notably, Dr. Bektaş was one of the first scientists to publicly identify Hop Latent Viroid (HLVd) in cannabis populations, a discovery that reshaped the industry's approach to disease management. What is Hop Latent Viroid (HLVd)? HLVd is a serious plant disease that infects cannabis, hop plants, and other medicinal plants like stinging nettle. Infected cannabis plants can suffer a significant reduction in cannabinoids and terpenes, drastically lowering both their monetary and medicinal value. Dr. Kirk and Dr. Bektaş explore the origins of HLVd, how it spreads, what to look for in affected plants, prevention strategies, and how innovative genetics are helping cannabis plants overcome this disease. 🎙️ Key Topics Discussed: Why Hop Latent Viroid is a game-changer in the cannabis industry The science behind its spread and early warning signs Effective prevention and management strategies The role of genetics in combating HLVd ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Read Dr. Bektaş recent piece in Cannabis Business Times  https://www.cannabisbusinesstimes.com/disease/cannabis-plant-disease/news/15686586/hop-latent-viroid-a-guide-to-sampling-testing-and-lab-selection Contact Dr. Ali Bektaş for further questions at ali@onsightdx.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
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4 months ago
1 hour 6 minutes

BIOACTIVE
Cannabis Suppositories with Nurse Megan Mbengue
On this episode of Bioactive, Dr. Riley Kirk sits down with Megan Mbengue, RN, MS. Megan is the owner of the cannabis company The Trusted Cannabis Nurse. She formulates custom products for patient specific needs as well as selling whole plant formulations through her website.  The conversation discusses a recent study that Megan completed implementing the use of suppositories for pain relief during menstrual periods. Megan shares her study on the effectiveness of suppositories for period pain. The study involved 103 participants who completed two menstrual cycles, one without suppositories and one with suppositories. The results showed a significant decrease in pain scores, with an average drop of 55%. The suppositories were found to be most effective on days one and two of the menstrual cycle. Most participants used the suppositories during the day, and some also used them at night. Overall, the study demonstrated the potential of suppositories as a natural and effective option for managing period pain. The conversation covers the effectiveness of suppositories in reducing pain and improving quality of life. The data from the study shows that 94% of participants reported a reduction in pain and 85% reported an improvement in quality of life. Suppositories were found to be effective in relieving period cramps, nausea, headaches, migraines, and improving focus. The duration of the effects varied, with most participants reporting relief for 3-4 hours. The conversation also touches on the accessibility and legality issues surrounding suppositories and the need for more research on their use in conditions like cancer and pelvic pain. Nothing in this podcast is ever medical advice. Buy Megan’s products or learn more: https://www.trustedcannanurse.com/ Patreon members will have access to the entire study PDF including all figures and additional data. Join the patreon for as little as $1/month Patreon.com/Cannabichem  Read about cannabis and orgasms: https://pmc.ncbi.nlm.nih.gov/articles/PMC9854104/ Follow Megan on social media: @TrustedCannaNurse keywords suppositories, menstrual pain, pain relief, study, effectiveness, period cycle, pain scores, suppositories, pain relief, quality of life, period cramps, nausea, headaches, migraines, focus, duration, accessibility, legality, cancer, pelvic pain takeaways Suppositories can be an effective option for managing period pain. The study showed a significant decrease in pain scores, with an average drop of 55%. Learn more about your ad choices. Visit megaphone.fm/adchoices
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4 months ago
51 minutes

BIOACTIVE
Top Cannabis Research From 2024 & What's New for Bioactive in 2025!
🌱 In this episode of Bioactive, host Dr. Riley Kirk dives into her favorite cannabis research publications from 2024, sharing groundbreaking insights that advanced our understanding of this incredible plant. 📖 Exciting News! Dr. Kirk's upcoming book, Reefer Wellness: Understanding Cannabis as Medicine, is AVAILABLE FOR PRE-ORDER now! 👉 Order Here ✨ In this episode: Highlights of key cannabis research papers from 2024. Sneak peek at upcoming Bioactive Season 2025 guests. New Year's cannabis resolutions for 2025. Insight into Reefer Wellness, a must-read for anyone passionate about cannabis medicine. 📚 Read the research papers mentioned in the episode: Cannabis Study in PMC Advancements in ScienceDirect Research in PubMed ACS Journal Natural Products Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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5 months ago
27 minutes

BIOACTIVE
Smuggling Cannabis: Tales and Tribulations with Ken Behr
In this engaging conversation, Ken Behr shares his remarkable journey from a dyslexic child who struggled in school to a successful writer and former drug smuggler. He discusses the challenges he faced growing up, the influence of his family, and the cultural shifts he experienced moving to Florida during the rise of drug culture in the 1970s. Ken recounts his early experiences with cannabis, the transition to smuggling, and some of the wild stories from his past, including a dramatic plane smuggling incident that highlights the risks and adventures of that lifestyle. In this segment, Ken Behr shares his experiences in the world of drug smuggling, detailing the techniques and precautions taken during operations. He recounts high-stakes smuggling trips, the risks involved, and the consequences of getting caught, including a harrowing jail experience. The conversation shifts to the legal system, the role of lawyers, and the empathy he feels for those caught in the criminal justice system. Finally, Ken discusses his transition from smuggler to collaborator with the DEA, reflecting on the complexities of crime and punishment. In this conversation, Ken Behr shares his journey from being a drug smuggler to working with the DEA, highlighting the struggles he faced, the complexities of the justice system, and the evolution of cannabis understanding. He reflects on the modern cannabis industry, expressing his excitement about the changes and the importance of access to cannabis for all. The discussion also touches on the need for rehabilitation in the justice system and the impact of cannabis on society. Donate to Freedom Grow https://freedomgrow.org/ Purchase or listen to One Step Over the Line https://onestepovertheline.com/ Join the Bioactive Patreon:  Patreon.com/Cannabichem  Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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5 months ago
1 hour 13 minutes

BIOACTIVE
Lit and Legit: Breaking the Stigma Surrounding Women in Media and Cannabis Use
Host Riley Kirk interviews Sarah Burke, the founder of Women in Media Network and her new producer!  They explore the intersection of cannabis, science, media, and the evolving perception of cannabis in society, especially as it pertains to women. They question some of the advertising challenges that the cannabis industry and content creators within it face, while looking at accepted habits and attitudes towards alcohol. They talk about content creation in the cannabis industry and its inevitable difficulties with censorship. Dr. Kirk emphasizes the medicinal benefits of cannabis and the importance of community knowledge and research in truly understanding its effects. Find out more about Sarah Burke and the Women in Media Network: https://www.womeninmedia.network/ https://www.instagram.com/burketalks/ https://www.instagram.com/wimnetwork/  Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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6 months ago
55 minutes

BIOACTIVE
FIRST New York Cannabis Event & Research Updates #NAPTIME with Dr. Miyabe Shields
Dr. Miyabe Shields and Dr. Riley Kirk: Leaders in Cannabis and Natural Products Research Dr. Miyabe Shields and Dr. Riley Kirk, co-founders of the nonprofit organization The Network of Applied Pharmacognosy (NAP), are at the forefront of research and education in cannabis science and natural products. Through their work, NAP conducts national and international studies exploring diverse topics such as cannabis consumption patterns, consumer trends, emerging products, vape and lab testing, and data-driven insights into the natural products industry. Tune in as they share cutting-edge science, discuss critical challenges in the industry like solvent contamination and testing inconsistencies, and recount their experiences at global events like MJBizCon in Las Vegas. Learn how they tackle conference chaos, network with industry leaders, and navigate the ever-changing landscape of cannabis and natural product research. Get Involved with NAP's Research and Community Initiatives: Join the Kava/Kratom Study: Sign up here Learn more about Kava and Kratom or subscribe to NAP’s newsletter: Read the blog Participate in our Flower Mill Giveaway: Head to @BioactivePodcast on Instagram and comment something that rhymes with "MILL" on the post featuring the Flower Mill (live on 11/16/24). Stay informed, get involved, and discover the intersection of science, industry, and community with Dr. Shields, Dr. Kirk, and NAP. Learn more about your ad choices. Visit megaphone.fm/adchoices
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6 months ago
1 hour 13 minutes

BIOACTIVE
The Science and Magic of Sungrown Cannabis
🌱 The Science and Magic of Sungrown Cannabis | Bioactive Podcast 🌱 Join Dr. Riley Kirk and an inspiring panel of experts — Tina Gordon, Lindsay MaHarry, Colleen King, and Christina Wong — as they dive deep into the unique qualities of sungrown cannabis! Recorded after their 2024 Emerald Cup panel discussion, this episode explores the unparalleled benefits of cultivating cannabis in natural sunlight and the artistry behind it. 🌿 In This Episode: What Makes Sungrown Cannabis Unique: Discover the science and the magic that sunlight brings to cannabis cultivation and the experiences it creates. Quantifying the Sungrown Difference: Learn about the measurable (and immeasurable) qualities that set sungrown cannabis apart. Marketing and Educating Consumers: Strategies to effectively promote and distribute sungrown cannabis while educating consumers on its distinct qualities. Sungrown Cannabis Perspectives: Get insights from experts across various fields, including cultivation, distribution, journalism, cooking, and cannabis science. 🎉 Giveaway Alert! Congrats to @Ecologica_Projects for winning this week’s giveaway! Stay tuned for another chance to win next week. Check out the Full Panel Discussion at the Emerald Cup 2024: Watch Here ✨ Follow Us on Social Media: @MoonMadeFarms @_OysterGirl @FruitandFlower @ColleenColleen @BioactivePodcast @Cannabichem 📢 Support Cannabichem on Patreon for exclusive content: Patreon.com/Cannabichem 👉 Keywords: Sungrown cannabis, cannabis cultivation, Emerald Cup 2024, cannabis education, organic cannabis, cannabis science, sustainable cannabis, Bioactive Podcast Learn more about your ad choices. Visit megaphone.fm/adchoices
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7 months ago
1 hour 54 minutes

BIOACTIVE
The Expanded Entourage Effect: Curating your cannabis experience with your consumption method
How Consumption Methods Affect Cannabis Chemistry | Dr. Riley Kirk | Bioactive Podcast In this episode of the Bioactive Podcast, Dr. Riley Kirk breaks down how cannabis consumption methods—whether smoking, vaping, or edibles—can impact the chemistry and effects you experience. We often focus on strain-specific effects to curate our cannabis experience, but your method of consumption also plays a key role. Different methods produce unique combinations of compounds, changing how you experience the Entourage Effect. This theory, introduced by Dr. Ethan Russo, explains how the many compounds in cannabis work together synergistically—often making the whole experience greater than the sum of its parts. But did you know the entourage effect varies with each consumption method? Dr. Riley Kirk shares her personal insights into how smoking, vaping, and edibles produce different results. Learn how to tailor your cannabis experience by understanding the relationship between strains and consumption methods. Subscribe to the Bioactive Podcast for more insights into cannabis science and chemistry, and join our Patreon community for early access to episodes and bonus content. Visit www.Patreon.com/cannabichem or contact Riley at BioactivePodcast.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
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7 months ago
38 minutes

BIOACTIVE
Understanding Cannabinoid Hyperemesis Syndrome (CHS) with Dr. Codi Peterson, & Megan Mbengue
In this episode of the Bioactive Podcast, we dive deep into a lesser-known but serious condition known as Cannabinoid Hyperemesis Syndrome (CHS). Join host Dr. Riley Kirk and guests Dr. Codi Peterson and Megan Mbengue as they explore the paradox of CHS, where in some rare cases, regular cannabis use leads to severe nausea, vomiting, and abdominal pain, despite cannabis being commonly used for its anti-nausea properties. We discuss the symptoms, the prodrome phase, and the potential genetic components that may predispose individuals to CHS. The episode also highlights an ongoing study being conducted by Dr. Kirk, Dr. Peterson and Megan Mbengue with the University of California, Irvine, aimed at understanding CHS better and improving diagnosis and treatment options. Listeners will learn about the unique relief some patients find in hot showers and capsaicin cream, as well as the challenges healthcare professionals face in diagnosing this condition. We also touch on the importance of understanding the role of THC, CBD, and other cannabinoids in relation to CHS, and the implications for cannabis users. Whether you're a cannabis consumer, a healthcare professional, or just curious about CHS, this episode provides valuable insights and encourages participation in the ongoing research to better understand this complex syndrome. Links to the study and more resources are available in the show notes! Don't forget to like, subscribe, and share your thoughts in the comments below! Link to take part in the CHS Study: https://uci.questionpro.com/CHS-P1 Join the Bioactive Patreon: https://www.patreon.com/cannabichem Learn more about your ad choices. Visit megaphone.fm/adchoices
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8 months ago
1 hour 8 minutes

BIOACTIVE
How to avoid moldy weed with Jini Glaros, MS
In this video, Riley interviews Jini Glaros, the Chief Science Officer (CSO) at Modern Canna, about groundbreaking research on the relationship between water activity and moisture content in cannabis. Whether you're part of an MSO, a home grower, or just passionate about cannabis science, understanding how these factors influence product quality, shelf life, and data accuracy is essential. Watch as Jini shares key insights from her experiments and discusses how this information can help improve industry standards and reporting practices. Don’t miss out on these valuable takeaways that can elevate your knowledge and practices in cannabis cultivation and quality control. 🔍 Topics Covered: - The science of water activity vs. moisture content - Why this research is crucial for cannabis growers - How MSOs and home growers can apply these findings - Improving cannabis industry standards through better data Jini's Bio: Jini Glaros is the Chief Scientific Officer (CSO) at Modern Canna Labs in Lakeland, FL. She received her bachelor’s degree with honors in Biochemistry from the University of West Florida. In May of 2022, Jini earned a master’s degree in Medical Cannabis Science and Therapeutics from the University of Maryland, Baltimore. Before entering the cannabis industry, Jini gained valuable research experience at several well-respected institutes, including Emory University, the National Institute of Aging, and the University of Florida. She became the laboratory director of Modern Canna in January of 2018 and was promoted to CSO in August of 2022. Jini is extremely involved in the cannabis industry and currently serves on the Scientific Advisory Board for CannMed and CloudLIMS, is a member of the CASP Proficiency Testing Advisory Task Force with AOAC International, is a member of the Cannabis Working Group (D37) with ASTM International, and is a member of the Cannabis Working Group with the American Council of Independent Laboratories. Want to ask guests questions ahead of time and get exclusive content? Join the Bioactive Patreon: https://www.patreon.com/cannabichem Jini can be reached on LinkedIn at: https://www.linkedin.com/in/jini-glaros-m-s-3105b382/ and more research from Modern Canna can be found here: https://moderncanna.com/research/ delta8 impurity research: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608670/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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8 months ago
1 hour 8 minutes

BIOACTIVE
A Philosopher's Guide to the Cannabis Industry with Jason Wilson
Dr. Riley Kirk is joined by Jason Wilson, MS on this episode of Bioactive. The two share many interests in self-exploration of the brain with drugs, navigating their own paths in the cannabis industry, thoughts on open access science, and more. Jason is a neurodivergent scientist and excellent science communicator. He is the host of the podcast Isn’t Life Curious which is the new name after years of being the Curious about Cannabis Podcast. Jason is passionate about providing accessible educational material for consumers and medical patients. This is the longest episode of Bioactive so far, and is a great journey in self exploration and navigating challenges in life. We first start with Jason’s story of exploration then move into philosophy and the sciences. Both Jason and Riley note the books by Alexander Shulgin in this episode which we’re happy to report are now much more affordable and can be found on Amazon and other book stores for $20 or so. If you love this podcast drop a 5 star review wherever you listen to podcasts or consider joining the Bioactive Patreon for as little as $1/month. Learn more about Jason Wilson with his full bio: Jason Wilson is a biologist, educator, and artist with over ten years of professional experience in the cannabis industry and over fifteen years experience as a medical cannabis patient. Growing up in Mississippi, Jason got his early exposure to Cannabis science at the University of Mississippi's Cannabis Research and Development laboratory fixing lab equipment as an IT technician while studying philosophy and psychology. He went on to study science education and biology as a graduate student in Oregon where he worked as a botanist for the Bureau of Land Management studying and working to restore native plant populations across a wide array of ecoregions. Upon graduating he went on to help build one of the first accredited Cannabis testing and research laboratories in the state. After spending several years developing analytical methods, testing thousands of products, and performing research, Jason went on to run a research and development laboratory for a vertically integrated hemp cultivator and product manufacturer in southern Oregon where he conducted research projects on decarboxylation efficiency, sub and supercritical fluid extraction efficiency, ethanol extraction efficiency, filtration and refinement efficacy, homogeneity, product stability, and more. Currently, Jason conducts natural product research out of his lab, Natural Learning Laboratories, while serving as a laboratory operations specialist for a tech startup and instructional designer for Abstrax Tech. He is the author of Curious About Cannabis: A Scientific Introduction to a Controversial Plant, now in its third edition, and the host of the Isn't Life Curious? podcast. Each year, he leads the Curious About Cannabis Master Class, an intensive program focused on cannabis and cannabinoid science. He guest lectures and speaks at conferences on topics related to natural product quality, cannabis science, and psychedelics. In his free time, Jason enjoys creating music, painting, gardening, and exploring nature. OTHER RESOURCES Weird Brains Article https://www.greenstate.com/lifestyle/weird-brains/ Budtender crash course: https://learn.naturaledu.com/pages/budtenders Cbd extraction paper with spellman: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638139/ Curious about cannabis book: https://cacpodcast.com/book/ Bioactive Patreon Patreon.com/cannabichem Learn more about your ad choices. Visit megaphone.fm/adchoices
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9 months ago
1 hour 48 minutes

BIOACTIVE
Dr. Riley Kirk is a cannabis research scientist and educator. She obtained her Ph.D. in pharmaceutical sciences, specializing in natural product chemistry, studying the traditional and contemporary uses of hundreds of medicinal plants. She is currently an assistant associate professor at the University of Rhode Island, has worked as an immunology scientist in the biotech industry, and works in the cannabis industry studying the chemical complexity of cannabis smoke. Riley is also the co-founder of the cannabis research and education non-profit organization called the Network of Applied Pharmacognosy (NAP). Through NAP and on her podcast, Riley uses science as advocacy to research and communicate findings that highlight the unique power of natural products. The goal of Riley’s work is to unite people in the Cannabis industry, academia, and consumers to further the reach of Cannabis education and reduce harm. Riley is passionate about making Cannabis science accessible through social media channels and alternative media which lead to Bioactive; an educational podcast which disseminates the chemistry and pharmacology of natural products. On this bi-weekly podcast, she covers current news and research surrounding cannabis, psychedelics, toxins, pharmaceuticals & other bioactive substances. Listen for special guests highlighting community stories.