In the season four premiere of 'Big Blonde and Beautiful,' host Karolina Howie shares personal updates, including her health struggles, and introduces the episode's focus on the musical 'Chicago.' She discusses the Broadway history of the show, its adaptations, and the significance of diversity in casting, particularly with Ashley Graham's recent announcement as Roxie. The conversation delves into the representation of fat characters in musicals, highlighting Queen Latifah's portrayal of Matron Mama Morton and the complexities of such roles.