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Beyond Biotech - the podcast from Labiotech
Labiotech
161 episodes
1 day ago
RNAi has changed the way that rare diseases are treated - is it about to do the same for more common conditions? Alnylam was the very first company to translate RNAi from Nobel Prize winning science into a commercially scalable platform. Founded in 2002, the company today has five different RNAi therapies on the market and a pipeline that continues to expand. While their early focus was on rare disease, today they are expanding into more common conditions, partnering with top pharma companies...
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All content for Beyond Biotech - the podcast from Labiotech is the property of Labiotech and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
RNAi has changed the way that rare diseases are treated - is it about to do the same for more common conditions? Alnylam was the very first company to translate RNAi from Nobel Prize winning science into a commercially scalable platform. Founded in 2002, the company today has five different RNAi therapies on the market and a pipeline that continues to expand. While their early focus was on rare disease, today they are expanding into more common conditions, partnering with top pharma companies...
Show more...
Tech News
News
Episodes (20/161)
Beyond Biotech - the podcast from Labiotech
How RNAi is expanding from a therapy of choice for rare disease into treating common conditions
RNAi has changed the way that rare diseases are treated - is it about to do the same for more common conditions? Alnylam was the very first company to translate RNAi from Nobel Prize winning science into a commercially scalable platform. Founded in 2002, the company today has five different RNAi therapies on the market and a pipeline that continues to expand. While their early focus was on rare disease, today they are expanding into more common conditions, partnering with top pharma companies...
Show more...
1 day ago
48 minutes

Beyond Biotech - the podcast from Labiotech
Are next-generation psychedelics the way forward for addressing treatment resistant depression?
Nearly 1 billion people around the world suffer from mental health disorders, with the global economic cost of those disorders expected to reach $6 trillion by 2030. One of the most common of those mental health disorders is depressive disorder, commonly called depression, with some 280 million people suffering from either mild, moderate or severe depression. Conventional treatments for depression such as selective serotonin reuptake inhibitors, or SSRIs, can work for many people but fo...
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1 week ago
49 minutes

Beyond Biotech - the podcast from Labiotech
Day One DNA: How and why the UK is betting on whole genome sequencing for every newborn
The UK is preparing to change the game for healthcare - but why, how, and what will it cost? Recently the UK government announced plans to sequence the DNA of every baby born in that country. A part of the country’s 10 Year Health Plan, the program aims to identify rare genetic diseases early, prevent harms from delayed treatment and reduce future healthcare costs for the NHS. Yet along with those potential upsides come a range of ethical and practical questions, too: who guards the sequenced...
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2 weeks ago
49 minutes

Beyond Biotech - the podcast from Labiotech
Meatly's innovative cultivated meat is already delighting pets, are humans next?
Is cultivated meat the future of pet food? And is there a place for cultivated meat on human dinner tables, too? Traditional agricultural methods are slow, require large tracts of land, significant energy and environmental inputs, and – somewhat obviously – the slaughter of hundreds of millions of animals every year. Cultivated meat – that is meat that is grown in a lab – requires little land, less energy, and in the case of Meatly, nothing more than a single cell from a single chicken egg, o...
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3 weeks ago
38 minutes

Beyond Biotech - the podcast from Labiotech
Cryoport Systems on the state of the ATMP market and the importance of supply chain resilience
With supply chain management and optimization, risk management, and the capacity to address global markets efficiently and effectively top of mind for all growing biotechs, I'm excited to be joined by Alison Pritchard, Vice President, Business Development at Cryoport Systems, to learn more about how they support life science innovators worldwide. Cryoport Systems evolved alongside the life science industry and expanded its capabilities into full-scale supply chain management solutions t...
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4 weeks ago
48 minutes

Beyond Biotech - the podcast from Labiotech
Taking the fight to inflammatory disease: InflaRx’s first-in-class C5a/C5aR signaling pathway strategy
Inflammatory diseases involve excessive or ongoing inflammation that damages tissues and affects many different human systems, including digestion, immunity, circulation, breathing, and the nervous system. The demand for anti-inflammatory treatments is growing quickly and is tipped to top a quarter of a trillion dollars within the decade as cases increase and new approaches to address inflammation emerge. This week, I had the chance to talk to Niels Riedemann, CEO and Founder of InflaRx, abou...
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1 month ago
39 minutes

Beyond Biotech - the podcast from Labiotech
How OMass Therapeutics is tackling congenital adrenal hyperplasia, a rare genetic disorder
Ros Deegan is an industry leader and the CEO of OMass Therapeutics, an Oxford-based biotechnology company discovering medicines against highly-validated target ecosystems, such as membrane proteins or intracellular complexes. OMass’s MC2 program targeting Congenital Adrenal Hyperplasia, or CAH, is set to enter the clinic this year and in our interview today she walks me through how the company is preparing for their trials, how their approach differs to existing treatment options, and ...
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1 month ago
34 minutes

Beyond Biotech - the podcast from Labiotech
Persica Pharmaceuticals is treating the cause of chronic lower back pain, not just the symptoms
The World Health Organization reports that more than 600 million people suffer from lower back pain globally, making it the leading cause of disability worldwide. Chronic lower back pain – where the pain persists for more than 3 months – develops in between 5 and 10% of all lower back pain cases, with life-altering impacts for patients. And that’s where today’s guest, Steve Ruston, of Persica Pharmaceuticals comes in. Persica is developing a groundbreaking and transformative treatment f...
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1 month ago
38 minutes

Beyond Biotech - the podcast from Labiotech
Humacyte: Saving lives with lab-grown blood vessels in conflict zones
Trauma surgeons in Ukraine operating theaters saved lives and limbs thanks to the innovative lab-grown blood vessels from US biotech, Humacyte. Humacyte is pioneering a platform that enables the investigation, development, and manufacture of bioengineered human tissues and organs that are designed to be universally implantable, off-the-shelf, and regenerative, with the goal of treating a wide variety of diseases, injuries, and chronic conditions. This week I had the chance to speak to Humacyt...
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1 month ago
36 minutes

Beyond Biotech - the podcast from Labiotech
Special Episode: The 2025 BIO International Convention
Much of the attention of the biotech industry has been focused on the city of Boston this week as the annual BIO International Convention hit town. BIO is the world’s largest partnering conference for the biopharma industry and thousands of innovators, out-licensors, venture capitalists, top pharma dealmakers, thought leaders and more than a few politicians gathered for three days of meetings, presentations, and networking. In this week’s episode we meet three innovators on the floor in...
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2 months ago
38 minutes

Beyond Biotech - the podcast from Labiotech
Alex Telford on AI, drug discovery, digital twins, and the most interesting questions in biotech
What are the most interesting questions in biotech, and is it even possible to find answers to those questions? Alex Telford is the co-founder of Convoke and a biotech blogger from the San Francisco Bay Area. His blog post, 'Some questions about biotech that I find interesting' provoked conversations online as readers engaged with questions about topics as diverse as the impacts of regulation, the role of serendipity in drug discovery, clinical trial failure rates, and the best structure for ...
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2 months ago
46 minutes

Beyond Biotech - the podcast from Labiotech
Corporate venture capital and biotechnology in 2025: challenges, opportunities, and threats
When biotechs start fundraising they regularly turn to the venture capital market seeking investment. The pool of VC money can be large, and part of that pool is corporate venture capital. Backed by firms keen to identify the next big thing in biotechnology, corporate VC money can be an attractive way for biotechs to raise funds privately while benefiting from the support and expertise of corporate supporters. This week I talked with Paolo Di Giorgio and Regina Hodits of Angelini Ventures, th...
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2 months ago
42 minutes

Beyond Biotech - the podcast from Labiotech
The state of biotech finance and fundraising in Q2 2025 with Baker McKenzie
Biotechnology has always been a dynamic domain, but the world of finance that provides the fuel for the fire is just as vibrant. Trying to predict where the market for biotech investment is heading is always risky but for experts like Baker McKenzie’s Roel Meers, understanding where the market is moving is where he eats. I spoke to Roel this week to unpack just where biotech funding stands in Q2 2025, to get a feel for the sorts of M&As, IPOs, and licensing deals we should be looking for ...
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2 months ago
39 minutes

Beyond Biotech - the podcast from Labiotech
How generative AI and 'Photoshop for proteins' are transforming biopharma R&D
Generative artificial intelligence (GenAI) is already changing how people research, communicate, and interact, but its biggest impacts on biotech are still to come. Cradle is a Dutch-Swiss biotech startup founded in 2021 that has developed a web-based software platform leveraging GenAI to accelerate protein design and optimization, aiding scientists in biotechnology R&D. Cradle’s technology integrates AI with wet lab experimentation, doubling the speed of most projects compared to industr...
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3 months ago
35 minutes

Beyond Biotech - the podcast from Labiotech
Fighting mucopolysaccharidosis type I, a rare disease, by reprogramming B-cells
There are cell therapies, gene therapies, and biologics – and then there is Immusoft. Immusoft sits at the nexus point of some of the most innovative approaches in biopharma, and their Immune System Programming platform is unique in its capacity to address the rare disease, MPS I. This week we talk with Immusoft CEO Sean Ainsworth to learn more about his journey in biotechnology, the work that Immusoft is doing in B-cell reprogramming and unpack some of the positive results that t...
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3 months ago
33 minutes

Beyond Biotech - the podcast from Labiotech
Inside Flagship Pioneering's strategy: How this VC turns ideas into biotech giants
Flagship Pioneering doesn't go out to find the next big thing in biotech when investing their billions in fund capital - instead, they take a different route. Flagship Pioneering has founded more than 100 companies in the life sciences worth in total an estimated $75 billion. With a proven model for biotech startup success and a culture designed to surface new and interesting ideas, Flagship offers a different approach to biotech funding that is paying off time and again. In this episode I ta...
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3 months ago
44 minutes

Beyond Biotech - the podcast from Labiotech
TCR-NK: A novel cell therapy transforming cancer treatment
Are TCR-NK treatments the next big thing in cell therapies for cancer patients? As biotechs and pharma companies continue to innovate to address patient needs in oncology, T-cell receptor therapies, or TCR-Ts, are attracting significant interest and investment. There are already some promising results for TCR-Ts tackling solid tumors – but one Norwegian biotech is taking a slightly different track. This week, we sit down with Namir Hassan, CEO of Zelluna, a company with a mission to eliminate...
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3 months ago
34 minutes

Beyond Biotech - the podcast from Labiotech
AI in biotech today, and how it will impact the industry tomorrow
AI is driving innovation across industries, including biotech, but where is its influence felt most and what opportunities for future impact are emerging? David del Bourgo is the co-founder and CEO of WhiteLab Genomics, an innovative biotech that is leveraging the power of AI to accelerate drug discovery and development from its Paris, Boston, and Montreal bases. In this episode he explains how WhiteLab uses AI technologies to identify targets and engineer vectors, but also offers a wider vie...
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4 months ago
39 minutes

Beyond Biotech - the podcast from Labiotech
How nanobodies will revolutionize immunotherapy
From llamas and camels to humans worldwide. Nanobodies are enjoying success in the clinic and experts are hailing these camelid-derived biologics as one of the next big things in immunotherapy. Kristian Reich is co-founder and CSO of MoonLake Immunotherapeutics. After a long and distinguished career as a clinician and researcher, Kristian helped to launch MoonLake in 2021 and quickly helped move their lead candidate to the clinic. Now, on the verge of Phase III trials, he joins 'Beyond Biotec...
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4 months ago
41 minutes

Beyond Biotech - the podcast from Labiotech
Meeting the global demand for cell therapies: scaling with smart manufacturing
Cell therapies are at the cutting edge of personalized medicine but as demand for these therapies grows, how will the industry scale manufacturing to meet patient needs? Fabian Gerlinghaus is co-founder and CEO of Cellares. He and his team have developed the Cell Shuttle, an advanced cell manufacturing technology that is already demonstrating the potential to 10x cell yields while halving costs for pharmaceuticals companies and innovators. Is this the future for smart cell manufacturing? 0:52...
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4 months ago
39 minutes

Beyond Biotech - the podcast from Labiotech
RNAi has changed the way that rare diseases are treated - is it about to do the same for more common conditions? Alnylam was the very first company to translate RNAi from Nobel Prize winning science into a commercially scalable platform. Founded in 2002, the company today has five different RNAi therapies on the market and a pipeline that continues to expand. While their early focus was on rare disease, today they are expanding into more common conditions, partnering with top pharma companies...