In this monolog, Casey discusses a 2024 article about the increase in health and lifespan in mammals after IL-11 inhibition.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources: Inhibition of IL-11 signalling extends mammalian healthspan and lifespan | Nature (https://www.nature.com/articles/s41586-024-07701-9)

In this monolog, Vijay discusses the difference in immune system development in term and pre-term babies.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources: https://pubmed.ncbi.nlm.nih.gov/30142345/

In this monolog, Akshat ponders about the spatiotemporal underpinnings of cytokine concentrations in tissue niches...and how it all appears to function like a gossip network.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Collectivist Model: https://www.nature.com/articles/s43018-020-0038-2Rapid Switching Model: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562415/Competitive Model: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126146/Leaky Synapses: https://www.nature.com/articles/nri3242

In this episode, Akshat outlines the salient features of CAR or TCR-engineered T cells, and deigns to ponder: is one modality just objectively better than the other?Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)

In this Monolog, Casey discusses the unique case of a hyper-vaccinated individual in Germany with more than 200 COVID-19 vaccines and how his immunological profile looks like.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00134-8/fulltext

In this Monolog, Akshat discusses how the liver "speaks" both immunity and metabolism via bile to control hepatic tumors. Liver X Receptors also make an appearance.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:https://www.science.org/doi/10.1126/science.aan5931 (https://www.science.org/doi/10.1126/science.aan5931)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433546/ (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433546/)

In the 29th episode of our Immunology 101 series, Ash and Tanu start the new year 2024 with a discussion on Barrier Immunity with a focus on the gut.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In this monologue, Akshat talks about sterile inflammation, or leucocyte activation in the absence of inflammatory responses. These carefully regulated "internal affairs" of the immune system can be pathological or protective.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Send us your queries/questions/suggestions at antibuddies1@gmail.com.

In this monolog, Casey talks about a 2023 article from the National Institute of Biological Sciences (Beijing, China) about the role of cytokines and immune cells in sleep deprivation-induced mortality.Source: Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals - PubMed (nih.gov) (https://pubmed.ncbi.nlm.nih.gov/38016470/)Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Send us your queries/questions/suggestions at antibuddies1@gmail.com.

In this monolog, Vijay talks about a 2016 article from Rockefeller University about the complex crosstalk in the gut between the neurons and macrophages.Source: Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages - PubMed (nih.gov) (https://pubmed.ncbi.nlm.nih.gov/26777404/)Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Send us your queries/questions/suggestions at antibuddies1@gmail.com.

In the 28th episode of our Immunology 101 series, Ash and Jatin continue the discussion on cytotoxic T cells and transition into their functional cousins - the natural killer cells.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In the 27th episode of our Immunology 101 series, Ash and Jatin talk about how cytotoxic T cells deliver the kiss of death to their targets.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In the 26th episode of our Immunology 101 series, Ash and Jatin shift gears from humoral immunity to cellular immunity and discuss cytotoxic T cell activation.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In the 25th episode of our Immunology 101 series, Koshika and Jatin discuss Fc receptors and Antibody isotypes and relate them to specific effector functions.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In the 24th episode of our Immunology 101 series, Ash and Jatin discuss the various effector functions of AntibodiesCheck out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In the 23rd episode of our Immunology 101 series, Ash, Koshika, and Jatin discuss the events taking place inside the germinal center - class switching and somatic hypermutation.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In the 22nd episode of our Immunology 101 series, Ash, Koshika, and Jatin talk about the events of the germinal centers.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In the 21st episode of our Immunology 101 series, Ash and Jatin talk about the fate of the B cell after it encounters the antigen and how it travels through the various compartments of a secondary lymphoid organ.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Sources:Kuby Immunology

In this Buddisode, we sit down with Dr. Nataliya Prokhnevska to discuss her work on the fate and role of non-cytotoxic CD8+ T cells found in the tumor-draining lymph nodes of cancer patients.Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Check out our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw (https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw)Send us your queries/questions/suggestions at antibuddies1@gmail.com.Article of discussion: CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor - PubMed (nih.gov) (https://pubmed.ncbi.nlm.nih.gov/36580918/)

In this monolog, Vijay talks about a recent article from the University of Miami describing the communication between the vagus nerve and the pancreas.Source: https://www.sciencedirect.com/science/article/abs/pii/S0016508520353233?via%3DihubCheck out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).Website: Antibuddies – Science Communication & Immunology (https://antibuddies.org/) (Antibuddies.org)Send us your queries/questions/suggestions at antibuddies1@gmail.com.