With former 49ers coach Jim Harbaugh and the Los Angeles Chargers visiting Levi's Stadium for Saturday's preseason finale, San Francisco's final roster decisions are becoming more clear. Matt Maiocco and Jennifer Lee Chan discuss what will play into the 49ers' roster choices, including injury updates, player suspensions and position-group competitions. Also, Matt and Jennifer review how the entire 2025 NFL Draft class has fared throughout training camp, and discuss Kyle Shanahan's update on veteran wide receiver Demarcus Robinson's suspension following his violation of the NFL's personal conduct policy last season.

The 49ers won their second preseason game in dramatic fashion over the Las Vegas Raiders on Saturday at Allegiant Stadium after kicker Jake Moody converted a career-long 59-yard field goal to seal San Francisco's 22-19 comeback victory. Matt Maiocco and Jennifer Lee Chan break down the 49ers' nail-biting performance and how they've grown since their Week 1 preseason loss to the Denver Broncos, including quarterback Brock Purdy and receiver Ricky Pearsall's burgeoning connection. Matt and Jennifer analyze this crucial relationship on offense, update on San Francisco's injuries and highlight other top 49ers performers from the win.

The 49ers began their second joint practice of the NFL preseason in Las Vegas much like their first week, undermanned. Undeterred, they fielded enough players against the Raiders to see some progress from last week. "49ers Talk" hosts Matt Maiocco and Jennifer Lee Chan break down which players were making the biggest impact in the second week of preseason and discuss two emerging rookies on both sides of the ball already making a case for regular-season minutes. Also, Matt and Jennifer update San Francisco's expansive injury room and share Kyle Shanahan's strategy for getting his starters some live reps throughout the rest of the preseason.

Matt Maiocco and Jennifer Lee Chan break down the vastly different approaches taken by the 49ers and Broncos in their preseason game on Saturday at Levi's Stadium, with Denver choosing to play many of its starters and San Francisco sitting its own. Maiocco and Chan discuss which 49ers players made the biggest impressions on the coaching staff, and others who still have work to do. Matt and Jennifer also provide 49ers injury updates and share what to look for entering Week 2 of the preseason against the Las Vegas Raiders.

A handful of familiar faces took the field in Santa Clara on Thursday as the 49ers hosted the Denver Broncos for a joint practice ahead of Saturday's preseason opener. "49ers Talk" co-hosts Matt Maiocco and Jennifer Lee Chan discuss how San Francisco's offense and defense fared against Denver, as well as an update on Mykel Williams after the rookie left Thursday's practice with a knee injury. Also, we'll hear from 49ers star QB Brock Purdy about San Francisco's resilience against the Broncos' stout defense.

Matt Maiocco and Jennifer Lee Chan check in after two weeks of 49ers training camp to break down which positions have the most competition and how Ricky Pearsall and Brock Purdy are continuing to develop their chemistry on the field.

Upton Stout joins "49ers Talk" to discuss his experience so far at training camp and who is helping mentor him during his rookie season. Matt Maiocco and Jennifer Lee Chan also break down the team's list of injuries and how stars Brock Purdy and Christian McCaffrey have looked.

The first full week of 49ers training camp might have brought more questions than answers, especially within San Francisco's wide receiver corps. Second-year wideout Ricky Pearsall made his return to the field Sunday following a nagging hamstring injury, while veteran receiver Jauan Jennings left early with a calf injury as Isaiah Neyor continued to impress. Matt Maiocco and Jennifer Lee Chan discuss how these recent developments will shape a receivers room primed for a player to emerge. Matt and Jennifer also review some of the 49ers' recent injuries following a scary practice incident, then check in on the kicking competition.

With all 49ers players slated to report to Santa Clara on Tuesday, training camp officially begins for an organization primed for a bounce-back season. "49ers Talk," hosts Matt Maiocco and Jennifer Lee Chan were in attendance for GM John Lynch and head coach Kyle Shanahan's opening press conference and a few question marks lingered. How will a wide receiver room marred by injury and contract disputes gel with quarterback Brock Purdy, did San Francisco do enough with their offensive and defensive lines and will the rookies emerge to play prominent roles on a team with aspirations for a title? Matt and Jennifer discuss how their questions will be answered. Also, Matt Maiocco makes a big announcement in regards to a new role with NBC Sports Bay Area.

Sportscaster Rich Eisen sits down with Matt Maiocco to weigh in on the 49ers' ability to bounce back this coming season. Eisen also reminisces on his humble broadcast television beginnings in Northern California, his rise to ESPN and hosting his own show. Eisen's familiarity with the Pacific Northwest and especially 49ers fans provide him the credibility and insight to label San Francisco as one of the NFL's most "underrated," fanatic franchises. Additionally, Jennifer Lee Chan joins Matt to break down wide receiver Jauan Jennings' contract extension request and how his value stacks up against other marquee receivers in the league.

Star 49ers fullback Kyle Juszczyk joins NBC Sports Bay Area's Matt Maiocco on "49ers Talk" during the American Century Championship in South Lake Tahoe to discuss his busy offseason. Juszczyk was briefly released and then re-signed with San Francisco earlier in the offseason, an experience he described as one of the 'worst' in his life. Now reunited and ramping up for 49ers training camp in a couple weeks, Juszczyk describes how thankful he is to stick with the organization that has helped define his storied career, which he and Matt also reflect on. Also, Jennifer Lee Chan joins Matt to provide health updates on wide receiver Brandon Aiyuk and safety Malik Mustapha while also sharing an important announcement from the McCaffrey family. Later, Matt talks with criminal defense attorney Todd Bequette to explain the potential league and legal ramifications of the 49ers' players' run-ins with the law.

Star 49ers tight end George Kittle sits down with Matt Maiocco during his first American Century Championship in Tahoe in the midst of a busy NFL offseason. From hosting his annual Tight End University summit and singing with Taylor Swift to training with his new neighbor Brock Purdy at the Barn in Tennessee, Kittle has made the most of his time off the gridiron. Kittle details how he manages all of his offseason commitments while still maintaining a training regimen, reveals a budding rivalry with first-round draft pick Mykel Williams and shares how he can help rookies get ready for the rigors of training camp. Also, Jennifer Lee Chan joins Matt to break down San Francisco's upcoming training camp dates and discuss an update in Demarcus Robinson's legal case.

Former NFL quarterbacks Ryan Fitzpatrick and Matt Ryan sat down with "49ers Talk" host Matt Maiocco to break down the San Francisco's chances of turning around their fortunes this season. First, Fitzpatrick, now an analyst for Amazon Prime, gives his take on the Week 5 rivalry game between the 49ers and Los Angeles Rams. He also shares his perspective on fellow Harvard alum Kyle Juszczyk, as well as the attributes Purdy honed in high school in Arizona that have served him well as a professional. Then, Ryan, now an analyst for CBS Sports, dives into what Kyle Shanahan looks for in a quarterback, having worked with the coach during the most successful part of his own professional career, and how Purdy can take his game to the next level under Shanahan's tutelage.

"49ers Talk" hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco’s veteran free agent additions this offseason before flashing back to a conversation with GM John Lynch about offseason acquisitions TE Luke Farrell, S Jason Pinnock and DB Tre Brown. Matt then sits down with Pinnock to discuss teaming up with his former coach Robert Saleh again and what new wrinkles in his game he’ll bring to the 49ers.

"49ers Talk" hosts Matt Maiocco and Jennifer Lee Chan debate if general manager John Lynch could make a big-name acquisition this offseason and discuss San Francisco’s defensive line and secondary depth. Jennifer then catches up with 49ers backup quarterbacks Mac Jones and Tanner Mordecai at George Kittle’s Tight End University to discuss the good vibes in the 49ers’ locker room during OTAs and minicamp, and what they have been learning from Brock Purdy.

"49ers Talk" co-host Jennifer Lee Chan visits the fifth annual Tight End University (TEU) in Nashville, Tenn., an event hosted by San Francisco tight end George Kittle, Kansas City Chiefs star Travis Kelce and NFL alum and FOX Sports analyst Greg Olsen. Jennifer and Matt Maiocco discuss the 49ers' tight position group and break down the numerous activities surrounding TEU. Jennifer then catches up with new 49ers tight end Luke Farrell, who is attending the event for the first time, and asks about how he has settled with his new teammates. Also, Kittle speaks with Jennifer about how the event has grown over the years and how excited he is for the upcoming season. Later, Matt and Jennifer address cornerback Deommodore Lenoir's arrest and release for obstruction of justice.

Second-year 49ers wide receiver Ricky Pearsall sits down with NBC Sports Bay Area's Matt Maiocco to reflect on his tumultuous rookie season in the NFL, a season that saw him traumatically shot in an attempted robbery before he worked his way into San Francisco's offense with some explosive performances. Pearsall opens up with Matt about how that moment has changed his life and how thankful he is to still be playing today. Also, Matt and Jennifer discuss Pearsall's harrowing rookie season experience and what to expect from him in his sophomore season.

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan review the the tumult surrounding the 49ers' 2024 offseason. Renewed and refreshed, San Francisco is poised to return in 2025 with a vengeance. Then, 49ers general manager/president of football operations John Lynch sits down with Matt to break down how San Francisco's offseason transformation can catapult the team from its recent substandard results.

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan report back from San Francisco's mandatory minicamp. The duo discusses injury updates on important players and how their recovery timelines will affect the 49ers' position groups. Also, Matt and Jennifer address the noticeable change in atmosphere around the organization after veteran offensive lineman Trent Williams described a team rejuvenated by rest and reflection.

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss their biggest takeaways from San Francisco's second week of its offseason program. Veteran defensive end Nick Bosa has embraced the role of mentor to the 49ers' young linemen, especially first-round draft pick Mykel Williams, who has looked every bit the part in practice. Also, Matt and Jennifer revisit backup quarterback Mac Jones' 2021 draft night and his journey to joining the 49ers, where he feels he can best develop.